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Chinese Journal of Structural Chemistry 2006年第10期25卷 1238-1242页

作者： SHI Jing-Min ZHANG Feng-Xia ZHANG Xia XU Hai-Yan liu lian-Dong MA jian-Ping Department of Chemistry Shandong Normal University Jinan 250014 China

Two Cd（Ⅱ） coordination polymers have been synthesized with pyrazine-1,4-dioxide （L1）, 2-methylpyrazine-1,4-dioxide （L2）, and thiocyanate anion as mixed bridge ligands. Crystal data for complex 1 [Cd（μ1,3-SCN^-）2（L1）]n： monoclinic system, space group P21/n with a = 6.8342（11）, b = 14.349（2）, c = 10.5443（16）°A,β = 98.534（2）°, V = 1022.5（3）°A^3 Z = 4, C6H4CdN4O2S2, Mr = 340.65, Dc = 2.213 g/cm^3, F（000） = 656 and u = 2.527 mm^-1; and those for 2： triclinic system, space group P/ with a = 7.877（3）, b = 8.693（3）, c = 8.754（3） °A, α= 102.297（6）,β= 102.464（6）, γ= 98.480（6）°, V= 560.0（3） °A^3, Z = 2, CTH6CdN4O2S2, Mr = 354.68, Dc = 2.103 g/cm^3, F（000） = 344 and μ= 2.311 mm^-1. 1 shows a three-dimensional network structure, and along the c direction a one-dimensional chain is constructed by the coordination of Cd（Ⅱ） ions with μ1,3-SCN^- ligands, and the L1 bridging ligands made the chains connect each other leading to the formation of a three-dimensional structure. For 2, the one-dimensional chains along the b axis are generated by the coordination of L2 bridging ligands with Cd（Ⅱ） ions, and the chains are further joined by μ1,3-SCN^- bridging ligands forming a two-dimensional sheet structure on the （10 -1 ） plane. Both complexes 1 and 2 exhibit strong fluorescence emission.

关键词： .bridging ligands one-dimensional II Coordination Chinese Struct Chem dioxide and Thiocyanate SCN bridging Fluorescence of Cadmium Mixed Bridge Ligands dioxide Methylpyrazine thiocyanate anion

Endoscopy-assisted vitrectomy for severe ocular penetrating trauma with corneal opacity

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International Journal of Ophthalmology(English edition) 2024年第12期17卷 2256-2264页

作者： Yong-Zhen Yu liu-lian jian Wen-Xiao Chen liang-Hong Peng Yu-Ping Zou Long Pang Xiu-Lan Zou Department of Ophthalmology General Hospital of Southern Theatre CommandGuangzhou 510010Guangdong ProvinceChina University of Traditional Chinese Medicine Guangzhou 510405Guangdong ProvinceChina Naval Medical University Shanghai 200433China Department of Ophthalmology Guangdong Provincial Hospital of Traditional Chinese MedicineGuangzhou 510120Guangdong ProvinceChina

AIM:To assess the utility and efficiency of endoscopyassisted vitrectomy(EAV)for the treatment of corneal opacity in severe ocular ***:Patients who underwent fundus examination using a preoperative slit lamp and intraoperative endoscopy,followed by EAV and additional surgery were retrospectively *** oil removal and penetrating keratoplasty were used in selected eyes at postoperative *** measurements included the best corrected visual acuity(BCVA),intraocular pressure(IOP),findings of endoscopic fundus examination,and postoperative ***:Twenty-one eyes with severe ocular trauma and corneal opacity were followed up for *** detachment(RD)and vitreous haemorrhage(VH)were identified in 16 eyes(76.2%),RD only in four eyes(19.0%),and VH combined with intraocular foreign body in one eye(4.8%).All eyes underwent at least three ***-Ⅰ surgeries involved wound closure(100%),lens extraction(76.2%),and anterior vitrectomy(14.3%).Stage-Ⅱ surgeries involved scleral buckling(28.6%),membrane peeling(47.6%),retinal laser photocoagulation(100%)and silicone oil tamponade(100%)using ***-Ⅲ surgeries were conducted using endoscopy including silicone oil removal(52.4%),retinal laser photocoagulation(52.4%)and penetrating keratoplasty(28.6%).Nearly all eyes showed improvements in BCVA and *** there were no severe complications,glaucoma was noted in one eye,chronic hypotony in another eye,and band keratopathy in three ***:EAV is an effective adjunct for restoring ocular anatomical structures and visual function in the case of corneal opacity after severe ocular trauma.

关键词： corneal opacity endoscopy-assisted vitrectomy penetrating keratoplasty severe ocular trauma retinal detachment

Observation of topological charge transformations in acoustic vortex using passive periodic systems

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 140-147页

作者： Di-Chao Chen Xie liu Changqing Xu Da-jian Wu Ying Cheng Xiao-Jun liu School of Physics and Technology Nanjing Normal University Key Laboratory of Modern Acoustics School of Physics Nanjing University

Vortex transmutation utilizes a periodic system, which not only enables the alteration of the topological charge(TC) of unstable input vortices but also facilitates their transformation into stable structures. This approach is crucial for investigating the characteristics of vortices in various wave systems. Here, we achieve acoustic vortex TC transmutation by employing a welldesigned dual-structured plate external system(DPES). The interactions between the acoustic vortex and the finite-order discrete rotational symmetry lead to the transformation of its topological charge when complete rotational symmetry is broken to Nthorder discrete symmetry. Our results experimentally demonstrate the acoustic vortex TC transmutation based on passive artificial structures, enabling numerous applications in particle manipulation and information multiplexing as well as advancing our understanding and control over free-space acoustic vortices.

关键词： acoustic vortex topological charge transformation artificial structure

Prolonged Alzheimer-like Tau Hyperphosphorylation Induced by Simultaneous Inhibition of Phosphoinositol-3 Kinase and Protein Kinase C in N2a cells

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Acta Biochimica et Biophysica Sinica 2005年第5期37卷 349-354页

作者： Guo-Gang XU Yan-Qiu DENG Shi-Jie liu Hong-lian LI jian-Zhi WANG Department of Pothophysiology,Institute of Neuroscience,Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China DepartmentofPathophysiology InstituteofNeuroscienceTongjiMedicalCollegeHuazhongUniversityofScienceandTechnol

Co-injection of wortmannin（inhibitor of phosphatidylinositol-3 kinase,PI3K）and GF109203X（inhibitor of protein kinase C,PKC）into the rat brain was found to induce spatial memory deficiency andenhance tau hyperphosphorylation in the hippocampus of rat *** establish a cell model with durativeAlzheimer-like tau hyperphosphorylation in this study,we treated N2a neuroblastoma cells with wortmanninand GF109203X separately and simultaneously,and measured the glycogen synthase kinase 3（GSK-3）activity by γ-（32）P-labeling and the level of tau phosphorylation by Western *** was found that theapplication of wortmannin alone only transitorily increased the activity of GSK-3（about 1 h）and the level oftau hyperphosphorylation at Ser396/Ser404 and Ser199/Ser202 sites（no longer than 3 h）;however,a prolongedand intense activation of GSK-3（over 12 h）and enhanced tan hyperphosphorylation（about 24 h）wereobserved when these two selective kinase inhibitors were applied *** conclude that the simultaneousinhibition of PI3K and PKC can induce GSK-3 overactivation,and further strengthen and prolong the Alzheimer-like tau hyperphosphorylation in N2a cells,suggesting the establishment of a cell model with early pathologicalevents of Alzheimer’s disease.

关键词： Alzheimer’s disease(AD) tau glycogen synthase kinase 3(GSK-3) protein kinase C(PKC) phosphatidylinositol-3 kinase(PI3K) N2a cells

Mutual-structure weighted guided image filtering for depth map restoration

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Optoelectronics Letters 2025年第1期21卷 51-56页

作者： liu Zijian SONG jian CHEN Quanmin XU jiangtao Tianjin Key Laboratory of Imaging and Sensing Microelectronic Technology School of Microelectronics Tianjin University Spikesee Technology Co. Ltd.

Although guided image filtering(GIF) is known for preserving edges and fast computation, it may produce inaccurate outputs in depth map restoration. In this paper, a novel confidence-weighted GIF called mutual-structure weighted GIF(MSWGIF) is proposed, which replaces the mean filtering strategy in GIF during handling overlapping windows. The confidence value is composed of a depth term and a mutual-structure term, where the depth term is utilized to protect the edges of the output, and the mutual-structure term helps to select accurate windows during the structure characteristics of the guidance image are transferred to the output. Experimental results show that MSWGIF reduces the root mean square error(RMSE) by an average of 12.37%, and the average growth rate of correlation(CORR) is 0.07% on average. Additionally, the average growth rate of structure similarity index measure(SSIM) is 0.34%.

关键词： Wiener filtering

Preparation and Performance of Ternary Early Strength Agent and Quercetin Composite Cement Sealing Material

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 130-140页

作者： liu jian CHEN Meiting JI Xiaoli XU Chao WANG Chunmei Department of Safety Science and Engineering Anhui University of Science and TechnologyHuainan 232001China Key Laboratory of Mine Safety and High Efficient Mining Jointly Built by Province and Education Ministry Anhui University of Science and TechnologyHuainan 232001China Department of Chemical Engineering and Explosives Anhui University of Science and TechnologyHuainan 232001China

A ternary early-strengthening agent consisting of calcium formate+triethanolamine+lithium sulfate was compounded with quercetin to shorten the setting time of cementitious materials while ensuring their early *** optimum ratio of the three early-strengthening agents was determined as 0.5%calcium formate+0.04%triethanolamine+0.4%lithium sulfate by response surface *** effects of the ternary early-strengthening agent composed of calcium formate+triethanolamine(TEA)+lithium sulfate on cementitious pore sealing materials under the synergistic effect of quercetin were studied by means of the performance tests of compressive strength,fluidity,and setting time,and the microstructural characterizations of X-ray powder diffractometer(XRD),thermogravimetry(TG-DSC)and scanning electron microscopy(SEM).The study shows that the synergistic effect of ternary early-strengthening agent and quercetin forms a multi-performance composite admixture for cementitious *** best performance was obtained with the compounding scheme of 0.5%calcium formate+0.04%triethanolamine+0.4%lithium sulfate ternary early-strengthening agent and 0.05%*** compressive strength of 1,3,7,and 28 d are 94.8%,39.8%,42%,and 28%higher than those of the blank group,*** initial time and final setting time are 41 and 57 minutes,*** to the microscopic analysis,the network and fibrous C-S-H gels generated by ternary early-strengthening agents are attached to the surface promoted by quercetin,which forms skeleton support while thickening and solidifying the cement slurry,which enhances the early compressive strength of the cement-based materials.

关键词： sealing material ternary early-strengthening agent quercetin synergetic effect response surface methodology

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车载自组网中基于车辆密度的多跳广播协议

通信学报 2016年第12期37卷 32-41页

作者：黄家玮钟少华刘联海王建新中南大学信息科学与工程学院湖南长沙410083

在车载自组网中,介质访问控制协议(MAC)的转发效率直接影响了数据消息的多跳广播传输性能。现有方法通常在每跳覆盖范围内选择最远节点来承担转发任务,通过降低转发次数实现快速多跳广播覆盖。然而,通过仿真实验和模型分析,当车辆密度... 详细信息

在车载自组网中,介质访问控制协议(MAC)的转发效率直接影响了数据消息的多跳广播传输性能。现有方法通常在每跳覆盖范围内选择最远节点来承担转发任务,通过降低转发次数实现快速多跳广播覆盖。然而,通过仿真实验和模型分析,当车辆密度变大时,现有方法导致信道竞争的接入延时剧增。因此,提出了一种基于IEEE802.11p协议的多跳广播协议VDF,根据车辆密度自适应地选择转发节点。事故预警和在线游戏2种典型应用仿真实验结果表明VDF降低了全网广播消息的覆盖延时,同时取得了信道冲突程度和多跳覆盖速度的合理折中。

关键词：无线车载自组织网络介质访问控制协议广播 IEEE 802.11p

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan Zhao Yidan Zhang Xin liu jian Zhang Ya Gao Shuyue Li Cui Chang Xiang liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

Insights into spinal muscular atrophy from molecular biomarkers

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Neural Regeneration Research 2025年第7期20卷 1849-1863页

作者： Xiaodong Xing Xinzhu liu Xiandeng Li Mi Li Xian Wu Xiaohui Huang Ajing Xu Yan liu jian Zhang Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina College of Pharmacy Chongqing Medical UniversityChongqingChina

Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle *** is one of the most common genetic causes of mortality among infants aged less than 2 *** research is currently receiving more attention,and new candidate biomarkers are constantly being *** review initially discusses the evaluation methods commonly used in clinical practice while briefly outlining their respective pros and *** also describe recent advancements in research and the clinical significance of molecular biomarkers for spinal muscular atrophy,which are classified as either specific or non-specific *** review provides new insights into the pathogenesis of spinal muscular atrophy,the mechanism of biomarkers in response to drug-modified therapies,the selection of biomarker candidates,and would promote the development of future ***,the successful utilization of biomarkers may facilitate the implementation of gene-targeting treatments for patients with spinal muscular atrophy.

关键词： biomarkers disease progression gene-targeting therapy neurofilaments Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

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云服务支持下远程计算机网络系统开发分析

数字技术与应用 2019年第1期37卷 189-189,191页

作者：刘建连益阳职业技术学院湖南益阳413049

随着时代的不断发展,我国的信息技术也得到了迅速的发展。现阶段远程计算机网络系统连接方式也可以通过多种方式进行连接。主要包含了现阶段云服务技术,这项技术可以通过计算机远程控制,形成新的模式。这项技术应用了当前Windows的RAS技... 详细信息

随着时代的不断发展,我国的信息技术也得到了迅速的发展。现阶段远程计算机网络系统连接方式也可以通过多种方式进行连接。主要包含了现阶段云服务技术,这项技术可以通过计算机远程控制,形成新的模式。这项技术应用了当前Windows的RAS技术,进行计算机的远程连接工作。本文主要研究了远程计算机网络的构建模式以及相关的配置,进行系统开发方向上的研究,分析系统如何实现自动连接和数据访问等有效功能。

关键词：云服务远程计算机网络系统 RAS