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An acupuncture meta-analysis for optic atrophy Seven randomized,controlled trials

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Neural Regeneration Research 2009年第12期4卷 994-1001页

作者： mailan liu Lei Lan Yong Tang Fang Zeng Haiyan Yin Mei Huang Fanrong Liang Acupuncture and Tuina School Chengdu University of Traditional Chinese Medicine Chengdu 610075 Sichuan Province China

OBJECTIVE： To evaluate the efficacy and safety of acupuncture for optic atrophy. DATA SOURCES： A computer-based online search was conducted in Medline （1966-2008）, Embase （1986-2008）, the Cochrane Library （up to 2008）, Chinese Biomedical Literature Database （1975-2008）, China National Knowledge Infrastructure （1994-2008）, VIP Database （1989-2008）, Wanfang Database （1980-2008） and the National Research Register for ongoing trials. DATA SELECTION： Randomized, controlled trials addressing acupuncture treatment for patients with optic atrophy were included in this review. Inclusion criteria evaluated all forms of acupuncture therapy, such as filiform needle, electro-acupuncture, laser-acupuncture, acupressure, and auricular-acupuncture. Comparisons between acupuncture therapy and no treatment （blank） or placebo or Chinese medicine or Western medicine, as well as between acupuncture as an adjuvant and other treatments, were included. Exclusion criteria included studies comparing different forms of acupuncture therapy, different manipulations of acupuncture, and different acupuncture prescriptions, as well as non-randomized, controlled trials and animal studies. The domain-based evaluation criteria recommended by the guidelines in Chapter 8 of the Cochrane Handbook for Systematic Reviews of Interventions 5.0.1 was used to assess quality of the included studies. According to the type of outcome index, measurement data as assessed by weighted mean difference or standardized mean difference and 95% confidence interval; numeration data was estimated by relative risk and 95% confidence interval. Heterogeneity was analyzed by Meta-analysis using RevMan 5.0 software. MAIN OUTCOME MEASURES： Improved visual acuity and visual field was sought between treatment and control groups in the included articles. RESULTS： Seven randomized, controlled trials were included after screening and application of inclusion and exclusion criteria. However, the studies were of low methodological qual

关键词： acupuncture therapy optic atrophy effectiveness Meta-analysis

A central analgesic mechanism of acupuncture for migraine An ongoing functional MRI study

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Neural Regeneration Research 2013年第28期8卷 2649-2655页

作者： Lei Lan Yujie Gao Fang Zeng Wei Qin Mingkai Dong mailan liu Taipin Guo Fanrong Liang School of Acupuncture and Tuina Chengdu University of Traditional Chinese Medicine School of Traditional Chinese Medicine Ningxia Medical University Life Science Research Center School of Life Sciences and TechnologyXidian University

Shaoyang acupoints are the most frequently used in migraine treatment. However, the central anal- gesic mechanism remains poorly understood. Studies have demonstrated that single stimulus of the verum acupuncture in healthy subjects can induce significant connectivity or activity changes in pain- related central networks compared with sham acupuncture. However, these findings are not indicative of the central analgesic mechanism of acupuncture at Shaoyang acupoints. Thus, we recruited 100 migraine sufferers and randomly assigned them into five groups： Shaoyang uncommon acupoint, Shaoyang common acupoint, Yangming uncommon acupoint, non-acupoint control, and blank control groups. Subjects were subjected to evaluation of curative effects and functional MRI prior to and after 10 and 20 acupuncture treatments. All subjects were diagnosed by physicians and enrolled following clinical physical examination. Subjects were observed during 1-4 weeks after inclusion. At the fifth week, the first clinical evaluation and resting functional MRI were conducted. The Shaoyang uncom- mon acupoint, Shaoyang common acupoint, Yangming uncommon acupoint, and non-acupoint control grousp then were treated with acupuncture, five times per week, 20 times in total over 4 weeks. The second and third clinical evaluations and resting functional MRI screenings were conducted following 10 and 20 acupuncture treatments. The blank control group was observed during the 5 to 8 week pe- riod, followed by clinical evaluation and resting functional MRI. The aim of this study was to examine changes in brain functional activity and central networks in subjects with migraine undergoing acu- puncture at Shaoyang uncommon acupoints. This study provides a further explanation of the central analgesic mechanism by which acupuncture at Shaoyang acupoints treats migraine,

关键词： neural regeneration acupuncture and moxibustion migraine acupuncture analgesia central re-sponse functional MRI sessions of acupuncture continuous central activity study design grants-supported paper neuroregeneration

中医药文化融入针灸的英文教学在涉外卓越班的实践探索

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中国当代医药 2024年第8期31卷 132-136页

作者：于隽刘余田浩梅王超刘密刘迈兰阳晶晶刘金芝湖南中医药大学针灸推拿与康复学院湖南长沙410208

为了推动中医针灸在全球医学领域和国际社会的普及与传承,培育既精通专业技能又熟练掌握英语,并深植中医文化自信的高素质复合型人才变得至关重要。本文探讨了涉外针灸教学中文化元素关注不足的问题,并论述了中医药文化融入涉外针灸的... 详细信息

为了推动中医针灸在全球医学领域和国际社会的普及与传承,培育既精通专业技能又熟练掌握英语,并深植中医文化自信的高素质复合型人才变得至关重要。本文探讨了涉外针灸教学中文化元素关注不足的问题,并论述了中医药文化融入涉外针灸的英文教学的深远意义;笔者将中医药文化与英语的听、说、读、写及翻译五大能力相结合,形成了一种“五位一体”的综合教学模式,并将其应用于涉外针灸的研究生班和八年制卓越班,旨在全方位提高学生在针灸英语领域的专业能力和文化自信度,为涉外针灸人才的培养策略提供了有益的参考。

关键词：涉外针灸英文教学文化自信中医文化

基于BOPPPS教学模型的经络腧穴学在线参与式教学实践

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中国中医药现代远程教育 2024年第9期22卷 13-15页

作者：唐雨兰刘迈兰杨茜芸郁洁慕容志苗湖南中医药大学针灸推拿与康复学院湖南长沙410208

2022年因疫情反复,线上教学虽然已经相对完善,但是为了实现线上信息素养课程的有效教学,教师以有效教学理论为指导,以智慧树为教学平台,构建了基于BOPPPS教学模型的经络腧穴学线上课程的有效教学模式。文章通过教学实践,验证该模式的教... 详细信息

2022年因疫情反复,线上教学虽然已经相对完善,但是为了实现线上信息素养课程的有效教学,教师以有效教学理论为指导,以智慧树为教学平台,构建了基于BOPPPS教学模型的经络腧穴学线上课程的有效教学模式。文章通过教学实践,验证该模式的教学效果,并对教学进行反思,以期为高校线上平台教学提供参考。

关键词：在线教学参与式教学 BOPPPS教学模型教学实践

Cerebral fractional amplitude of low-frequency fluctuations may predict headache intensity improvement following acupuncture treatment in migraine patients

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Journal of Traditional Chinese Medicine 2020年第6期40卷 1041-1051页

作者： Li Zhengjie Zhou Jun Cheng Shirui Lan Lei Sun Ruirui liu mailan Yang Jie Gao Yujie Guo Taipin Gong Qiyong Zeng Fang Liang Fanrong Acupuncture&Tuina School/The Third Teaching Hospital Chengdu University of Traditional Chinese MedicineChengdu 610000China Acupuncture&Tuina School Hunan University of Chinese MedicineChangsha 410000China Huaxi Magnetic Resonance Research Center West China Hospital of Sichuan UniversityChengdu 610000China

OBJECTIVE:To explore how baseline resting-state cerebral function predicts clinical outcomes of acupuncture treatment for ***:One hundred migraine patients and 46 healthy subjects were *** were randomized into the acupuncture,sham acupuncture,and waiting list ***-state functional magnetic resonance imaging data were collected at baseline and after 1 month of longitudinal acupuncture *** amplitude of low-frequency fluctuations(f ALFF)calculations were applied to explore the associations between baseline f ALFF and changes in clinical variables in the acupuncture treatment group and the waiting list ***:Compared with healthy subjects,migraine patients had lower f ALFF in the left rostral ventromedial medulla,right thalamus,left amygdala,and right angular *** analyses revealed that baseline f ALFF values in the left middle frontal gyrus,left superior temporal gyrus,and middle temporal gyrus were positively associated with headache intensity changes in the acupuncture treatment group,while baseline f ALFF values in the bilateral lingual gyrus and cuneus were negatively associated with headache intensity changes in this ***:The baseline f ALFF values of brain regions associated with cognitive pain modulation,but not migraine severity,may predict future headache intensity improvement levels in migraine patients receiving acupuncture treatment.

关键词： Acupuncture Migraine disorders Treatment outcome Magnetic resonance imaging

隔药饼灸对动脉粥样硬化兔血清Ox-LDL、IFN-γ表达的影响

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湖南中医药大学学报 2024年第9期44卷 1614-1619页

作者：易洪芬陈昕羽彭涵肖孟霞欧阳里知刘红华刘迈兰湖南中医药大学针灸推拿学院湖南长沙410208 湖南中医药大学护理学院湖南长沙410208

目的观察隔药饼灸对动脉粥样硬化(atherosclerosis,AS)兔血清氧化低密度脂蛋白(oxidized low-density lipoprotein,Ox-LDL)、干扰素(interferon-γ,IFN-γ)的影响,探讨隔药饼灸抗AS的作用机制。方法将18只新西兰兔随机分为正常组、模... 详细信息

目的观察隔药饼灸对动脉粥样硬化(atherosclerosis,AS)兔血清氧化低密度脂蛋白(oxidized low-density lipoprotein,Ox-LDL)、干扰素(interferon-γ,IFN-γ)的影响,探讨隔药饼灸抗AS的作用机制。方法将18只新西兰兔随机分为正常组、模型组、隔药饼灸组,每组6只。正常组给予普通饲料喂养,其余2组给予高脂饲料喂养,其中隔药饼灸组边造模边干预:2组穴位(巨阙、天枢、丰隆;心俞、肝俞、脾俞)交替行隔药饼灸干预,每穴灸4壮,每日1次,干预12周。HE染色观察主动脉组织病理变化,比色法检测总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、低密度脂蛋白胆固醇(low density liporotein cholesterol,LDL-C)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)含量,ELISA法检测Ox-LDL、IFN-γ含量。结果与正常组比,模型组主动脉内皮明显增厚,平滑肌排列絮乱,泡沫细胞大量聚集,血清TC、TG、LDL-C、Ox-LDL、IFN-γ含量均显著升高(P<0.05,P<0.001),HDL-C含量显著下降(P<0.001)。与模型组比,隔药饼灸组主动脉内皮结构完整,平滑肌排列整齐,少见泡沫细胞,血清TC、TG、LDL-C、ox-LDL、IFN-γ含量均显著下降(P<0.05,P<0.01,P<0.001),HDL-C含量明显升高(P<0.05)。结论隔药饼灸可能通过降低AS兔血清Ox-LDL、IFN-γ含量,减少巨噬细胞脂质摄取,抑制泡沫细胞形成,发挥抗AS的作用。

关键词：动脉粥样硬化隔药饼灸氧化低密度脂蛋白干扰素-γ 泡沫细胞脂质

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基于CiteSpace探讨穴位埋线治疗单纯性肥胖的研究热点和趋势

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医学综述 2024年第15期30卷 1907-1914页

作者：陈昕羽易洪芬罗桃红李芊彭涵薛庆隆庄俭张浩琳刘迈兰湖南中医药大学针灸推拿与康复学院长沙410208 永州市零陵区中医医院针灸科湖南永州425100 北京化工大学北京100294 北京大学第三医院中医科北京100191

目的通过CiteSpace分析穴位埋线治疗单纯性肥胖的研究现状、热点与发展趋势。方法以中国知网数据库建库至2022年7月发表的穴位埋线治疗单纯性肥胖文献作为资料来源,将文献数据导入CiteSpace 5.8R3,对发文量、论文作者、研究机构、关键... 详细信息

目的通过CiteSpace分析穴位埋线治疗单纯性肥胖的研究现状、热点与发展趋势。方法以中国知网数据库建库至2022年7月发表的穴位埋线治疗单纯性肥胖文献作为资料来源,将文献数据导入CiteSpace 5.8R3,对发文量、论文作者、研究机构、关键词等进行可视化、关键词聚类和共现等分析,获得穴位埋线治疗单纯性肥胖的发展现状、研究热点与未来趋势。结果共纳入324篇文献,统计时间跨度为2004—2022年。穴位埋线治疗单纯性肥胖领域发文量呈现波动性上升,作者发文量偏少,各机构之间缺乏合作,主要机构为广西中医药大学、成都中医药大学及南京中医药大学第二临床医学院,其中广西中医药大学以发文量5篇位列榜首。关键词分析显示形成9个关键词聚类模块,可大致分为疾病证型、干预措施、疾病影响因素以及研究类型4个方面,提示热点疾病证型为脾虚湿阻型肥胖;主要干预措施为穴位埋线及其他中医疗法的联合干预,同时对于穴位埋线取穴规律的研究也较为重视;肥胖影响因素主要关注血脂和瘦素;研究类型主要是综述和临床研究。结论穴位埋线治疗单纯性肥胖的研究前景良好,研究的重点在于加强研究者及机构之间的合作,开展多中心、高质量的大型临床试验,进而探索最佳的埋线联合疗法以及取穴方案,探索穴位埋线对不同证型单纯性肥胖的疗效。

关键词：单纯性肥胖穴位埋线 CiteSpace 可视化

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针灸治疗高脂血症实验研究文献计量学分析

中医杂志 2015年第11期56卷 972-977页

作者：刘迈兰张佳丽赵钊刘密常小荣湖南中医药大学针灸推拿学院湖南省长沙市含浦科教园区410208

目的分析针灸治疗高脂血症实验研究的文献特征及研究现状。方法纳入中国知网、维普数据库、万方数据库和Pubmed数据库1993年1月至2013年12月期间针灸治疗高脂血症的实验研究文献,采用文献计量学方法,对其文献特征(论文发表年份、发表期... 详细信息

目的分析针灸治疗高脂血症实验研究的文献特征及研究现状。方法纳入中国知网、维普数据库、万方数据库和Pubmed数据库1993年1月至2013年12月期间针灸治疗高脂血症的实验研究文献,采用文献计量学方法,对其文献特征(论文发表年份、发表期刊、作者单位、基金资助)及实验特征(实验动物、造模方法、动物取材、观察指标、刺灸方法与选用穴位)进行统计分析。结果共纳入76篇中文期刊文献。发表年份以2011年为最多,共17篇;发表期刊中医类59篇(78%),针灸类17篇(22%);第一作者主要分布于中医药大学及其附属医院(71篇,93%);文献有市级基金资助5篇(7%),省部级基金资助30篇(39%),国家级基金资助21篇(28%)。高脂血症的实验动物以大鼠为主,共55篇,占72%;造模方法以高脂饲料喂养为主,共62篇,占82%,其次为腹腔注射75%蛋黄乳液7篇(9%);实验动物取材为血液64篇(84%),肝组织11篇(14%);血液的主要观察指标为总胆固醇51篇、甘油三酯51篇、高密度脂蛋白胆固醇46篇、低密度脂蛋白胆固醇46篇,肝组织的主要观察指标为ATP结合盒转运蛋白A1(5篇)、过氧化物酶体增殖物激活受体(3篇);穴位使用频次最高为丰隆穴23次,占总频次30%,其次为足三里(后三里)穴20次(26%),再次为神阙穴14次(18%);实验所用刺灸方法以针刺为主,共计52篇,占68%,其次艾灸21篇(28%)、针药结合3篇(4%)、穴位注射1篇(1%)。结论针灸治疗高脂血症实验研究近年呈现一定的增长及相对集中趋势;针灸治疗高脂血症穴位选择应全面考虑高脂血症虚、痰、湿、瘀的病机特点,关注针灸调脂效应对靶器官的保护作用。

关键词：高脂血症针灸疗法实验研究文献计量学

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针灸治疗高脂血症的选穴用经特点与规律分析

中国针灸 2015年第5期35卷 512-516页

作者：刘迈兰胡薇谢慎张佳丽赵钊刘密常小荣湖南中医药大学针灸推拿学院长沙410007

提炼并分析针灸治疗高脂血症选穴用经的特点和规律。通过检索主要中英文数据库,纳入有明确选穴的针灸治疗高脂血症的临床研究文献,分析针灸治疗高脂血症选穴用经的特点和规律。发现高脂血症针灸处方的选穴以特定穴为主,选穴频次居于前5... 详细信息

提炼并分析针灸治疗高脂血症选穴用经的特点和规律。通过检索主要中英文数据库,纳入有明确选穴的针灸治疗高脂血症的临床研究文献,分析针灸治疗高脂血症选穴用经的特点和规律。发现高脂血症针灸处方的选穴以特定穴为主,选穴频次居于前5位的依次为丰隆、足三里、三阴交、内关和天枢;高脂血症针灸处方的用经包括10条经脉,选用经脉频次较高的为胃经、脾经、任脉、膀胱经和心包经;高脂血症的针灸处方以胃经、脾经、任脉、膀胱经和心包经的特定穴为主。高脂血症的针灸处方体现了"从脾论治、循脾胃经取穴、远近结合""调整脏腑虚实、辨证取穴、前后结合"和"辨症取穴"的选穴特点。

关键词：高脂血症针灸选穴特点