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超高层单元体吊装技术及安装施工方法研究

棕点石斑鱼(♀)×清水石斑鱼(♂)杂交子代与亲本表型比较及遗传特征分析

建筑与装饰 2024年第1期 48-50页

作者：刘小春浙江亚厦幕墙有限公司浙江杭州 310008

超高层建筑幕墙单元体是一种非常普遍的建筑结构形式,被广泛地应用于目前的高档建筑工程中.本文以某商务办公楼超高层单元体吊装施工为例,采用框架式幕墙设计结构,计算超高层单元体吊装动力参数,按照超高层单元体的吊装技术要求,对超高... 详细信息

超高层建筑幕墙单元体是一种非常普遍的建筑结构形式,被广泛地应用于目前的高档建筑工程中.本文以某商务办公楼超高层单元体吊装施工为例,采用框架式幕墙设计结构,计算超高层单元体吊装动力参数,按照超高层单元体的吊装技术要求,对超高层单元体进行了吊装安装.实验结果表明,所提方法的超高层单元体吊装时间较短,能够有效提高实际施工效率.

关键词：超高层单元体吊装技术安装施工

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水生生物学报 2024年第3期48卷 444-453页

作者：王同方明宇杨扬宋乐玲蔡春有蒙子宁刘晓春中山大学生命科学学院有害生物控制与资源利用国家重点实验室广东省水生经济动物良种繁育重点实验室广州510006 海南晨海水产有限公司三亚572000 南方海洋科学与工程广东省实验室(珠海) 珠海519080

以棕点石斑鱼(Epinephelus fuscoguttatus)为母本、清水石斑鱼(***)为父本,开展了杂交育种试验,成功获得杂交子一代。由于棕点石斑鱼与清水石斑鱼外型相似,其杂交子代也与亲本难以区分,为探究双亲本与杂交子代表型差异和遗传差异,研究... 详细信息

以棕点石斑鱼(Epinephelus fuscoguttatus)为母本、清水石斑鱼(***)为父本,开展了杂交育种试验,成功获得杂交子一代。由于棕点石斑鱼与清水石斑鱼外型相似,其杂交子代也与亲本难以区分,为探究双亲本与杂交子代表型差异和遗传差异,研究利用外部形态数据及外型框架参数进行比较分析,同时使用微卫星标记对双亲本及杂交子代的遗传特征进行分析。在外部形态结构的探究中,杂交子代可量性状及外形框架更偏向于母本棕点石斑鱼。在遗传特征的分析中,采用ddRAD-seq技术在棕点石斑鱼上获得6266个微卫星标记,筛选出7对可以在双亲本及杂交子代中稳定扩增且遗传多样性较高的微卫星引物,其中,6对引物可以在部分群体中扩增出特异性条带以区分3个群体。通过分析,7个微卫星标记位点在杂交子代群体中的平均观测杂合度(H_(o))为0.891,平均期望杂合度(H_(e))为0.768,平均多态信息含量(PIC)为0.717,三者均高于双亲本,表明杂交子代在遗传信息的多样性方面有一定的提高。研究结果可为棕点石斑鱼、清水石斑鱼及两者杂交子代的鉴别提供方法,并为杂交石斑鱼的培育提供一定的理论基础。

关键词：杂交育种表型微卫星标记棕点石斑鱼清水石斑鱼

子宫动脉栓塞术联合超声引导下清宫术治疗子宫瘢痕妊娠的临床分析

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局解手术学杂志 2024年第8期33卷 689-692页

作者：王文珍魏凌云温亚玲刘小春山西白求恩医院(山西医学科学院)/同济山西医院/山西医科大学第三医院妇产科山西太原030032

目的探讨子宫动脉栓塞术(UAE)联合超声引导下清宫术治疗Ⅱ型、Ⅲ型子宫瘢痕妊娠(CSP)的临床效果。方法回顾性分析我院收治的90例CSP患者的临床资料,根据术前阴道彩超表现将患者分为Ⅱ型组和Ⅲ型组。2组患者均行UAE联合超声引导下清宫术... 详细信息

目的探讨子宫动脉栓塞术(UAE)联合超声引导下清宫术治疗Ⅱ型、Ⅲ型子宫瘢痕妊娠(CSP)的临床效果。方法回顾性分析我院收治的90例CSP患者的临床资料,根据术前阴道彩超表现将患者分为Ⅱ型组和Ⅲ型组。2组患者均行UAE联合超声引导下清宫术治疗。比较分析2组患者术中及术后情况。结果Ⅱ型组的治愈率(92.5%)高于Ⅲ型组(65.2%),Ⅱ型组患者术中阴道出血量、术后血清β-hCG转阴时间、术后病灶消退时间均少/短于Ⅲ型组,差异有统计学意义(P0.05)。结论对于孕周8~10周的Ⅱ型CSP患者,UAE联合超声引导下清宫术的治疗效果理想,可作为推荐的治疗方案。但对于Ⅲ型CSP患者,UAE联合超声引导下清宫术的治愈率较低,应考虑患者具体情况及当地医疗水平等综合选择。

关键词：子宫瘢痕妊娠子宫动脉栓塞术超声引导下清宫术经阴道超声

植物类胡萝卜素的代谢调控及储存转运研究进展

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亚热带植物科学 2024年第1期53卷 80-88页

作者：于银凤刘青青刘晓春张大生崔丽洁上海市植物种质资源工程技术研究中心/上海师范大学生命科学学院上海200234 上海辰山植物园/中国科学院分子植物科学卓越创新中心辰山科学研究中心上海201602 东台市新街镇综合服务中心江苏东台224234

类胡萝卜素是植物体内广泛存在的一类天然色素,一般由8个异戊二烯单元首尾相连而成的C40萜类化合物及其衍生物组成。在植物中,类胡萝卜素除了赋予植物器官呈色以外,在体内还执行着多项重要的生物学功能。近年来,虽然类胡萝卜素生物合成... 详细信息

类胡萝卜素是植物体内广泛存在的一类天然色素,一般由8个异戊二烯单元首尾相连而成的C40萜类化合物及其衍生物组成。在植物中,类胡萝卜素除了赋予植物器官呈色以外,在体内还执行着多项重要的生物学功能。近年来,虽然类胡萝卜素生物合成途径较为清晰,但是类胡萝卜素的代谢调控以及在体内的储存和转运机制还不明确。本文简要概述了类胡萝卜素的生物合成、代谢调控、储存定位和萜类物质转运蛋白等方面的研究进展,总结了介导类胡萝卜素转运的分子及鉴定转运体的方法,以期为研究类胡萝卜素的合成和转运提供参考。

关键词：类胡萝卜素代谢调控转运体

Serum 25-Hydroxyvitamin D Level Might Be a Useful Indicator of Disease Severity in Obese Children With Atopic Dermatitis:A Case-Control Study

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International Journal of Dermatology and Venereology 2024年第1期7卷 6-11页

作者： Jing-Jing Chen xiao-Kai Fang Xiu-Mei liu xiao-chun liu Xu Yao Department of Allergy and Rheumatology Hospital for Skin Diseases(Institute of Dermatology)Chinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210042China

Objective:To assess the relationship between the severity of atopic dermatitis(AD)in children of varying weight categories and their serum 25-hydroxyvitamin D[25(OH)D]***:The study population comprised 899 patients with AD and 854 age-and sex-matched *** Mann-Whitney U test and Kruskal-Wallis H tests were used to assess differences between groups,and Spearman correlation analysis was used to test ***:The 25(OH)D level in the AD group was M(Q_(25),Q_(75)),24.0(19.7,28.4)ng/mL,which was significantly lower than the control group(26.4[23.6,29.9]ng/mL;Z=-3.34,P=0.001).25(OH)D levels in children with AD were negatively correlated with body mass index(r=-0.30,P<0.001),Severity scoring of Atopic Dermatitis(SCORAD;r=-0.14,P<0.001),total immunoglobulin E(r=-0.13,P<0.001),and eosinophil(r=-0.08,P=0.017).There were statistically significant differences in 25(OH)D(H=18.46,P<0.001),total immunoglobulin E(H=9.13,P=0.010),eosinophil(H=67.17,P<0.001),and SCORAD(H=10.49,P=0.005)among groups with different body mass index *** 25(OH)D levels were 22.3(17.5,27.1)ng/mL in the overweight AD group and 22.3(17.6,25.7)ng/mL in the obese AD group,which were significantly lower than those in the normal-weight AD group(24.7[20.4,25.5]ng/mL;P=0.003,P=0.004).25(OH)D levels were negatively correlated with SCORAD in obese AD patients(r=-0.25,P=0.010).Conclusion:Vitamin D insufficient or deficient is obvious in children AD *** 25(OH)D levels in the overweight/obese AD group are significantly lower than those in the normal-weight AD *** D level is negatively correlated with SCORAD in obese children with AD.

关键词： atopic dermatitis vitamin D disease severity index immunoglobulin E body mass index eosinophil children overweight/obese

Effect of solute Ce,Mn,and Si on mechanical properties of silicon steel:insights from DFT calculations

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Journal of Iron and Steel Research(International) 2024年第3期31卷 700-709页

作者： Xiang-jun liu Ji-chun Yang Hui-ping Ren xiao-bin Jia Ming-yi Zhang Chang-qiao Yang School of Materials and Metallurgy Inner Mongolia University of Science and TechnologyBaotou 014010Inner MongoliaChina Key Laboratory of Integrated Exploitation of Bayan Obo Multi-Metal Resource Inner Mongolia University of Science and TechnologyBaotou 014010Inner MongoliaChina Inner Mongolia North Heavy Industries Group Co. Ltd.Baotou 014010Inner MongoliaChina Inner Mongolia Metal Material Research Institute Baotou 014010Inner MongoliaChina

The influence of solute Ce,Mn,and Si on the mechanical properties of silicon steel was investigated by first-principles ***,Mn,and Si can all be solubilized in Fe *** significantly reduces the incompressibility and rigidity of the system but also significantly improves the toughness and *** effect of Mn on mechanical properties of the system is not *** has a significant effect on the improvement in incompressibility and rigidity but a limited effect on the improvement in toughness and *** metallic bond strength of Fe-Ce,Fe-Mn,and Fe-Si doped systems is weaker than that of the pure Fe system,which can be used to explain the reduction in the incompressibility and rigidity of these doped *** relatively high electron cloud density in the doped system may be responsible for the increase in toughness.

关键词： Silicon steel Rare earth First-principles calculation Elastic modulus Electronic structure

Pb induced dislocation defects of PtCo systems: Strain-triggered oxygen reduction reaction for PEMFC

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Nano Research 2024年第4期17卷 2462-2472页

作者： chun Jin Qiheng Wang Jingjun liu Beijing Key Laboratory of Electrochemical Process and Technology for Materials Beijing 100029China Beijing University of Chemical Technology Beijing 100029China

Design and development of advanced electrocatalysts with high performance and low Pt consumption are crucial for reducing the kinetic energy barrier of the cathode oxygen reduction reaction(ORR)and improving the efficiency of proton exchange membrane fuel cells(PEMFC).In this study,we demonstrate a Pb-modulated PtCo system for efficient ORR,in which the inclusion of Pb in ternary alloys induces dislocation defects due to the significant difference in atomic ***-PtCoPb was confirmed to exhibit significantly higher ORR activity and stability in acidic *** practical PEMFC applications,it outperforms the corresponding commercial Pt/C with a mass activity of 0.58 A·mgPt^(-1),making it a promising alternative to state-of-the-art Pt-based *** combination of experimental results and density functional theory(DFT)calculations offers valuable atomic-level insights into the dislocation *** with a larger atomic radius is located in the lattice stretching region below the dislocation slip plane,forming a structure similar to a Cottrell atmosphere,which reduces the dislocation energy and puts the system in a lower energy *** Cottrell atmosphere pins the dislocation structure and stabilizes the ternary *** adjusting the amount of added Pb,a moderate level of dislocation density induces a tuned strain effect,thereby enhancing the electrocatalytic mechanism by optimizing the electronic structure of the alloy surface and the adsorption and desorption of oxygen *** work provides valuable insights into the design and development of lattice dislocation defect structures to trigger strain effects for improving ORR performance.

关键词： dislocation defect strain effect Pb-modulated oxygen reduction reaction

Hydrodynamic characteristics and particle tracking of 90° lateral intakes at an inclined river slope

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Water Science and Engineering 2024年第2期17卷 197-208页

作者： Wei He Si-yuan Feng Jian Zhang Hong-wu Tang Yang xiao Sheng Chen chun-sheng liu College of Water Conservancy and Hydropower Engineering Hohai UniversityNanjing 210098China State Key Laboratory of Hydrology Water Resources and Hydraulic Engineering Hohai UniversityNanjing 210098China Collaborative Innovation Center on Water Safety and Water Science Hohai UniversityNanjing 210098China

Lateral intakes are common in *** pump effciency and sediment deposition are determined by the local hydrodynamic characteristics and mainstream division *** hydraulic characteristics of lateral withdrawal from inclined river slopes at different intake elevations should be ***,the division width exhibits significant vertical non-uniformity at an inclined river slope,which should be ***,a three-dimensional(3-D)hydrodynamic and particle-tracking model was developed with the Open Source Field Operation and Manipulation(Open FOAM),and the model was validated with physical model tests for 90°lateral withdrawal from an inclined side *** flow fields,withdrawal sources,and division widths were investigated with different intake bottom elevations,withdrawal discharges,and main channel *** study showed that under inclined side bank conditions,water entered the intake at an oblique angle,causing significant 3-D spiral flows in the intake rather than two-dimensional closed recirculation.A lower withdrawal discharge,a lower bottom elevation of the intake,or a higher main channel velocity could further strengthen this *** average division width and turbulent kinetic energy were smaller under inclined side bank conditions than under vertical bank *** a low intake bottom elevation,a low withdrawal discharge,or a high main channel velocity,the sources of lateral withdrawal were in similar ranges near the local inclined bank in the vertical *** inclined slope conditions,sediment deposition near the intake entrance could be reduced,compared to that under vertical slope *** results provide hydrodynamic and sediment references for engineering designs for natural rivers with inclined terrains.

关键词： Lateral withdrawal Hydrodynamic characteristics Particle tracking Inclined river slope Bottom elevation of intake OpenFOAM

Analysis of the impact of immunotherapy efficacy and safety in patients with gastric cancer and liver metastasis

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 700-709页

作者： Kai liu chun-xiao Wu Hui Liang Tao Wang Ji-Yuan Zhang xiao-Tao Wang Department of Radiation and Oncology Traditional Chinese Hospital of Lu’an affiliated to Anhui University of Traditional Chinese MedicineLu’an 237000Anhui ProvinceChina Department of Gastroenterology Ehu branch of Xishan People’s Hospital of Wuxi CityWuxi 214116Jiangsu ProvinceChina Department of Gastrointestinal Surgery The First Affiliated Hospital of Guangzhou University of Traditional Chinese MedicineGuangzhou 510400Guangdong ProvinceChina Department of Gastrointestinal Surgery Hunan Provincial People’s HospitalChangsha 410002Hunan ProvinceChina Department of Traditional Chinese medicine Ehu branch of Xishan People’s Hospital of Wuxi CityWuxi 214116Jiangsu ProvinceChina

BACKGROUND Gastric cancer(GC)is the fifth most common type of cancer and has the fourth highest death rate among all *** is a lack of studies examining the impact of liver metastases on the effectiveness of immunotherapy in individuals diagnosed with *** To investigate the influence of liver metastases on the effectiveness and safety of immunotherapy in patients with advanced *** This retrospective investigation collected clinical data of patients with advanced stomach cancer who had immunotherapy at our hospital from February 2021 to January *** baseline attributes were compared using either the Chi-square test or the Fisher exact probability *** chi-square test and Kaplan-Meier survival analysis were employed to assess the therapeutic efficacy and survival duration in GC patients with and without liver *** The analysis comprised 48 patients diagnosed with advanced GC,who were categorized into two groups:A liver metastasis cohort(n=20)and a non-liver metastatic cohort(n=28).Patients with liver metastasis exhibited a more deteriorated physical condition compared to those without liver *** objective response rates in the cohort with metastasis and the cohort without metastasis were 15.0%and 35.7%(P>0.05),***,the disease control rates in these two cohorts were 65.0%and 82.1%(P>0.05),*** median progression-free survival was 5.0 months in one group and 11.2 months in the other group,with a hazard ratio of 0.40 and a significance level(P)less than *** median overall survival was 12.0 months in one group and 19.0 months in the other group,with a significance level(P)greater than *** Immunotherapy is less effective in GC patients with liver metastases compared to those without liver metastasis.

关键词： Gastric cancer Spread of cancer to the liver Treatment with immunotherapy Effectiveness of treatment