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TRH microinjection into DVC enhances motility of rabbits gallbladder via vagus nerve

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World Journal of Gastroenterology 1998年第2期4卷 70-72页

作者： liu, CY liu, jz Zhou, JH Wang, HR Li, ZY Li, AJ liu, KJ Shandong Univ Dept Physiol Jinan 250012 Shandong Peoples R China

AIM To investigate the effects of TRH in DVC on motility of the gallbladder in rabbits. METHODS After fasted for 15h - 18h , rabbits were anesthetized with urethane (1 0g/kg) . Gallbladder pressure (GP) was measured by a frog bladder perfused with normal saline. RESULTS After microinjection of TRH (8 8nmol, 1μl ) into DVC, GP was raised and the frequency of phasic contraction of gallbladder (FPCGB) increased. All the doses of TRH (0 13, 0 25, 0 50, 0 80, 1 30nmol , 1μl ) injected into DVC could excite the motility of gallblader. As the dose of TRH was enlarged, the amplitude and duration of the reaction increased. Effects of TRH in DVC on motility of the gallbladder could be completely abolished by atropine ( 0 2mg/g , i.v.) or vagotomy, but could not be inhibited by phentolamine iv (1 5mg/g) or propranolol iv (1.5mg/g) or by transecting the spinal cord. CONCLUSION Thyrotropin releasing hormone in DVC can excite motility of gallbladder. This effect was mediated by vagus nerves and peripheral M receptor. Its physiological significance may be related to maintaining the phasic contraction of gallbladder in interdigestive period.

关键词： gallbladder vagus nerve dorsal vagal complex thyrotropin releasing hormone cholinergic M receptors rabbits

Preliminary study on light hydrocarbons in ore-forming fluids of gold and antimony deposits in southwestern Guizhou, China

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Chinese Science Bulletin 1997年第20期42卷 1708-1711页

作者： Zhuang, HP Lu, JL Fu, JM liu, jz Shi, JX Chinese Acad Sci Guangzhou Inst Geochem Guangzhou 510640 Peoples R China

METAL minerals precipitate generally from ore-forming fluid. It is suggested that organic mat-ter in ore-forming fluid is one of the best media which show the role of organic matter in oregenesis. Because mineralizing temperatures of many ore deposits exceeded the stable rangesof liquid hydrocarbons, only light hydrocarbons were preserved well in inclusions. Thus,

关键词： southwestern Guizhou gold and antimony deposits light hydrocarbon.

Insights into spinal muscular atrophy from molecular biomarkers

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Neural Regeneration Research 2025年第7期20卷 1849-1863页

作者： Xiaodong Xing Xinzhu liu Xiandeng Li Mi Li Xian Wu Xiaohui Huang Ajing Xu Yan liu Jian Zhang Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina College of Pharmacy Chongqing Medical UniversityChongqingChina

Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle *** is one of the most common genetic causes of mortality among infants aged less than 2 *** research is currently receiving more attention,and new candidate biomarkers are constantly being *** review initially discusses the evaluation methods commonly used in clinical practice while briefly outlining their respective pros and *** also describe recent advancements in research and the clinical significance of molecular biomarkers for spinal muscular atrophy,which are classified as either specific or non-specific *** review provides new insights into the pathogenesis of spinal muscular atrophy,the mechanism of biomarkers in response to drug-modified therapies,the selection of biomarker candidates,and would promote the development of future ***,the successful utilization of biomarkers may facilitate the implementation of gene-targeting treatments for patients with spinal muscular atrophy.

关键词： biomarkers disease progression gene-targeting therapy neurofilaments Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

QNQL processes-- (H, Q)-processes and their applications

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Chinese Science Bulletin 1997年第11期42卷 881-886页

作者： Hou, ZT liu, ZM Zou, jz Research Department Changsha Railway University Changsha China

As we know,many scholars have been involved in the study of stochastic processes,whichhave a wide range of applications,such as the Markov *** the study of Markov pro-cesses,minimal Markov chain(*** minimal homogeneou... 详细信息

关键词： QNQL process (H Q)-process the backward equation the forward equation.

Climatic instability record during the Penultimate Glaciation: Evidence from Huining loess

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Chinese Science Bulletin 1997年第20期42卷 1720-1723页

作者： Ren, jz Ding, ZL liu, DS Quan, H China Japan Friendship Ctr Environm Protect Open Lab Beijing 100029 Peoples R China

THE investigations of past global changes reveal strong climatic instability during the lastglaciation. Most terrestrial palaeoclimate records have not given climatic conditionclues in the Penultimate Glaciation. It is very necessary for us to know whether the climaticinstability picture is a particular phenomenon occurring only in the last glacial period. In

关键词： China Loess Penultimate Glaciation climatic instability.

Fractals in Steel-Aluminum Solid to Liquid Bonding

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Journal of Materials Science & Technology 1999年第5期15卷 486-488页

作者： Zhang, P Du, YH Ren, XP Ba, LM liu, HW Cui, jz Univ Sci & Technol Beijing Sch Mat Sci & Engn Beijing 100083 Peoples R China Anshan Automobile Fittings Factory Anshan 114014 Peoples R China Northeastern Univ Met Forming Dept Shenyang 110006 Peoples R China

This paper studied the fractal characteristic of the interfacial shear surface of steel-Al solid to liquid bonding plate, and determined the relationship between fractal dimension and interfacial shear strength. The research results showed that the relationship between fractal dimension and interfacial shear strength could be described as y=26.2x+4.2 (where y was interfacial shear strength, x was fractal dimension) and when 08Al steel plate was coarsened by steel wire wheel which was made up with steel wires whose diameter were 1.4 similar to 1.6 mm, the optimum coarsening pattern of the steel plate surface could be got, the corresponding maximum interfacial shear surface fractal dimension of the bonding plate was 2.33, and the maximum interfacial shear strength of the bonding plate was 65.3 MPa.

关键词： Nature MPa

Measurement and Calculation of Quenching Rate Constants for PCl(b)

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Chinese Chemical Letters 1996年第12期7卷 1125-1126页

作者： Zou, SL liu, CP Guo, jz Gu, YS Chu, YN Cao, DZ SHANDONG UNIV DEPT CHEMJINAN 250100PEOPLES R CHINA ACAD SINICA ANHUI INST OPT & FINE MECHLASER SPECT LABHEFEI 230031PEOPLES R CHINA

Using the Ar(P-3(0.2)) +PCl3 reaction as a source of PCl(b(1) Sigma(+)). We have measured the quenching rate constants of PCl(b) for 23 reagents. The E -V model is used to calculate the rate constants. The comparison ... 详细信息

关键词： Measurement and Calculation of Quenching Rate Constants for PCl

Cloning and sequence analysis of human genomic DNA of augmenter of liver regeneration

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World Journal of Gastroenterology 2000年第2期6卷 275-277页

作者： Cheng J Zhong YW liu Y Dong J Yang jz Chen JM 302 Hosp PLA Gene Therapy Res Ctr Inst Infect Dis Beijing 100039 Peoples R China

INTRODUCTIONThe liver is one of the organs,which have potentialregenerative capability in mammalian *** study of the canine model indicated that theliver could regenerate to original size after 70%hepatectomy in only ... 详细信息

关键词： augmenter liver regeneration cloning genomic DNA intron exon

SYNTHESIS OF MESOPOROUS CHROMIUM SILICATE

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Chinese Chemical Letters 1995年第12期6卷 1091-1094页

作者： Yuan, ZY Chen, TH Wang, jz Li, HX liu, SQ Nankai Univ Dept Chem Catalysis Lab Tianjin 300071 Peoples R China Nankai Univ Catalyst Plant Tianjin 300071 Peoples R China

A mesoporous chromium silicate molecular sieve with MCM-41 structure has beers prepared by direct hydrothermal synthesis; XRD; framework IR, ESR and DR-UV spectroscopies provided evidence of the presence of framework ...

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