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供应链整合对食品企业创新绩效的影响研究——基于开放式创新的中介作用

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北京交通大学学报（社会科学版） 2024年第2期23卷 89-100页

作者：徐孝民刘孟凯郝丽君黄胜忠中国矿业大学(北京)管理学院北京100083 防灾科技学院应急管理学院河北廊坊065201

以京津冀地区211家食品企业为研究对象,采用问卷调查方式获取数据,探讨供应链整合对食品企业创新绩效的影响以及开放式创新的中介作用。其中,供应链整合包括供应商整合、客户整合与内部整合三种方式,开放式创新包含探索式创新与利用式... 详细信息

以京津冀地区211家食品企业为研究对象,采用问卷调查方式获取数据,探讨供应链整合对食品企业创新绩效的影响以及开放式创新的中介作用。其中,供应链整合包括供应商整合、客户整合与内部整合三种方式,开放式创新包含探索式创新与利用式创新两种模式。研究结果表明:供应商整合对食品企业创新绩效的直接影响显著,内部整合、客户整合的直接影响不显著;探索式创新在供应商整合、内部整合提升食品企业创新绩效的中介作用显著,利用式创新的中介作用不显著。因此,食品企业应重视供应商整合、注重内部整合、加强客户整合,且总体上应强调由内而外的探索式创新,从而促进创新绩效的提升。

关键词：供应链整合开放式创新结构方程模型竞争模型创新绩效

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Vav1 promotes inflammation and neuronal apoptosis in cerebral ischemia/reperfusion injury by upregulating microglial and NLRP3 inflammasome activation

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Neural Regeneration Research 2023年第11期18卷 2436-2442页

作者： Jing Qiu jun Guo Liang liu Xin liu Xianhui Sun Huisheng Chen Department of Neurology General Hospital of Northern Theater CommandShenyangLiaoning ProvinceChina Department of Neurology Tangdu HospitalAir Force Medical UniversityXi’anShaanxi ProvinceChina

Microglia,which are the resident macrophages of the central nervous system,are an important part of the inflammatory response that occurs after cerebral *** guanine nucleotide exchange factor 1(Vav1) is a guanine nucleotide exchange factor that is related to microglial ***,how Vav1 participates in the inflammato ry response after cerebral ischemia/reperfusion inj ury remains unclea *** this study,we subjected rats to occlusion and repe rfusion of the middle cerebral artery and subjected the BV-2 mic roglia cell line to oxygen-glucose deprivatio n/reoxygenation to mimic cerebral ischemia/repe rfusion in vivo and in vitro,*** found that Vav1 levels were increased in the brain tissue of rats subjected to occlusion and reperfusion of the middle cerebral arte ry and in BV-2 cells subjected to oxygen-glucose deprivation/*** Vav1 reduced the cerebral infarct volume and brain water content,inhibited neuronal loss and apoptosis in the ischemic penumbra,and im p roved neurological function in rats subjected to occlusion and repe rfusion of the middle cerebral *** analysis showed that Vav1 was almost exclusively localized to microglia and that Vav1 downregulation inhibited microglial activation and the NOD-like receptor pyrin 3(NLRP3) inflammasome in the ischemic penumbra,as well as the expression of inflammato ry facto *** addition,Vov1 knoc kdown decreased the inflammatory response exhibited by BV-2 cells after oxygen-glucose deprivation/reoxyge *** together,these findings show that silencing Vav1 attenuates inflammation and neuronal apoptosis in rats subjected to cerebral ischemia/repe rfusion through inhibiting the activation of mic roglia and NLRP3 inflammasome.

关键词： apoptosis cerebral ischemia/reperfusion inflammatory cytokines microglia microglial activation middle cerebral artery occlusion neuroprotection NLRP3 inflammasome oxygen-glucose deprivation/reoxygenation Vav1

仿真数据驱动的起重机钢丝绳断丝定量识别方法

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机电工程 2024年第1期41卷 43-51页

作者：王晓昆井陆阳白晓瑞战卫侠刘云成王彦松青岛理工大学机械与汽车工程学院山东青岛266520 海军工程大学兵器工程学院湖北武汉430032 软控股份有限公司山东青岛266000

针对工程应用中起重机钢丝绳损伤检测由于故障样本不足导致检测效果较差的问题,提出了一种仿真数据驱动的、基于卷积神经网络(CNN)模型的钢丝绳断丝定量识别方法。首先,使用有限元软件COMSOL对直径24 mm的6×37结构钢丝绳不同损伤类型... 详细信息

针对工程应用中起重机钢丝绳损伤检测由于故障样本不足导致检测效果较差的问题,提出了一种仿真数据驱动的、基于卷积神经网络(CNN)模型的钢丝绳断丝定量识别方法。首先,使用有限元软件COMSOL对直径24 mm的6×37结构钢丝绳不同损伤类型进行了建模与仿真,并将提离值为5 mm处仿真漏磁场减去背景磁场,得到了仿真损伤信号;其次,搭建了钢丝绳漏磁检测试验台,采集了与仿真参数一致的钢丝绳断丝实测信号,并进行了小波去噪处理,解决了实测信号中由于存在噪声干扰导致与仿真信号不匹配的问题;最后,建立了卷积神经网络模型,采用仿真数据辅助模型训练,并使用早停法抑制了模型对训练集中仿真数据的过拟合问题。以仿真数据作为训练集和仿真数据辅助小样本实测数据作为训练集,进行了实验验证。研究结果表明:仿真数据驱动、小波去噪能够较大幅度地提高断丝识别率;早停法能够较好地抑制实验中的过拟合问题;该方法在两种实验形式下的准确率分别达到了84.5%和97.5%,证明该方法能够有效识别钢丝绳损伤,具有一定的理论研究价值和工程应用前景。

关键词：起重机械电磁检测模式识别方法卷积神经网络小波变换小样本数据 COMSOL

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模糊认知图学习算法及应用综述

自动化学报 2024年第3期50卷 450-474页

作者：刘晓倩张英俊秦家虎李卓凡梁伟玲李宗溪北京交通大学计算机科学与技术学院北京100044 交通数据分析与挖掘北京市重点实验室北京100044 智慧高铁系统前沿科学中心北京100044 中国科学技术大学自动化系合肥230027

模糊认知图(Fuzzy cognitive map, FCM)是建立在认知图和模糊集理论上的一类代表性的软计算理论,兼具神经网络和模糊决策两者的优势,已成功地应用于复杂系统建模和时间序列分析等众多领域.学习权重矩阵是基于模糊认知图建模的首要任务,... 详细信息

模糊认知图(Fuzzy cognitive map, FCM)是建立在认知图和模糊集理论上的一类代表性的软计算理论,兼具神经网络和模糊决策两者的优势,已成功地应用于复杂系统建模和时间序列分析等众多领域.学习权重矩阵是基于模糊认知图建模的首要任务,是模糊认知图研究领域的焦点.针对这一核心问题,首先,全面综述模糊认知图的基本理论框架,系统地总结近年来模糊认知图的拓展模型.其次,归纳、总结和分析模糊认知图学习算法的最新研究进展,对学习算法进行重新定义和划分,深度阐述各类学习算法的时间复杂度和优缺点.然后,对比分析各类学习算法在不同科学领域的应用特点以及现有的模糊认知图建模软件工具.最后,讨论学习算法未来潜在的研究方向和发展趋势.

关键词：模糊认知图学习范式因果推理软计算复杂系统建模

Transforming growth factor-beta 1 enhances discharge activity of cortical neurons

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Neural Regeneration Research 2025年第2期20卷 548-556页

作者： Zhihui Ren Tian Li Xueer liu Zelin zhang Xiaoxuan Chen Weiqiang Chen Kangsheng Li Jiangtao Sheng Department of Microbiology and Immunology Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular ImmunopathologyShantou University Medical CollegeShantouGuangdong ProvinceChina Department of Neurosurgery First Affiliated Hospital of Shantou University Medical CollegeShantouGuangdong ProvinceChina

Transforming growth factor-beta 1(TGF-β1)has been extensively studied for its pleiotropic effects on central nervous system *** neuroprotective or neurotoxic effects of TGF-β1 in specific brain areas may depend on the pathological process and cell types ***-gated sodium channels(VGSCs)are essential ion channels for the generation of action potentials in neurons,and are involved in various neuroexcitation-related ***,the effects of TGF-β1 on the functional properties of VGSCs and firing properties in cortical neurons remain *** this study,we investigated the effects of TGF-β1 on VGSC function and firing properties in primary cortical neurons from *** found that TGF-β1 increased VGSC current density in a dose-and time-dependent manner,which was attributable to the upregulation of Nav1.3 *** VGSC current density and Nav1.3 expression were significantly abolished by preincubation with inhibitors of mitogen-activated protein kinase kinase(PD98059),p38 mitogen-activated protein kinase(SB203580),and jun NH2-terminal kinase 1/2 inhibitor(SP600125).Interestingly,TGF-β1 significantly increased the firing threshold of action potentials but did not change their firing rate in cortical *** findings suggest that TGF-β1 can increase Nav1.3 expression through activation of the ERK1/2-JNK-MAPK pathway,which leads to a decrease in the firing threshold of action potentials in cortical neurons under pathological ***,this contributes to the occurrence and progression of neuroexcitatory-related diseases of the central nervous system.

关键词： central nervous system cortical neurons ERK firing properties JNK Nav1.3 p38 transforming growth factor-beta 1 traumatic brain injury voltage-gated sodium currents

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康青12号青稞的选育及栽培技术要点

陕西农业科学 2024年第8期70卷 10-12页

作者：詹瑞玲江谧谢世刚张英杨开俊涂洋朱华忠刘军刘廷辉甘孜藏族自治州农业科学研究所四川康定626000 四川省农业科学院作物研究所四川成都610066

青稞在高原地区是第一大粮食作物,因其耐瘠、耐旱、耐寒、适应性强等特点成为高原地区的主要粮食作物。康青12号青稞是甘孜藏族自治州农业科学研究所以康青6号为父本,以藏青690为母本进行杂交选育而来的高产、优质春性品种。该品种生育... 详细信息

青稞在高原地区是第一大粮食作物,因其耐瘠、耐旱、耐寒、适应性强等特点成为高原地区的主要粮食作物。康青12号青稞是甘孜藏族自治州农业科学研究所以康青6号为父本,以藏青690为母本进行杂交选育而来的高产、优质春性品种。该品种生育期约为115 d,平均穗长10 cm,单株穗数2个,每穗结实50粒,单株粒重4.2 g,千粒重42 g;籽粒蛋白质含量为11.60%,淀粉63.93%,赖氨酸0.4%,β-葡聚糖3.76%;5点次试验得出康青12号平均籽粒产量为第1生长周期249.08 kg/667m^(2);第2生长周期241.83 kg/667m^(2)。

关键词：康青12号选育高产优质栽培技术

Simulated-sunlight-activated photocatalysis of Methylene Blue using cerium-doped SiO_2/TiO_2 nanostructured fibers

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Journal of Environmental Sciences 2012年第10期24卷 1867-1875页

作者： Yu liu Hongbing Yu Zhenning Lv Sihui zhan Jiangyao Yang Xinhong Peng Yixuan Ren Xiaoyan Wu College of Environmental Science and Engineering Nankai UniversityT'wnjin 300071China

Cerium-doped SiO2/TiO2 nanostructured fibers were fabricated by electrospinning technology. The prepared fibers were characterized by thermogravimetric analysis （TGA）, scanning electron microscopy （SEM）, X-ray diffraction （XRD） and Fourier transform infrared spectroscopy （FT-IR）. Using the fibers as catalysts, photoeatalytic degradation of Methylene Blue （MB） aqueous solution was carded out under simulated sunlight. The 0.2% Ce doping proved to be the optimal concentration for the doping of TiO2/SiO2, compared to other Ce-doped molar concentrations. The 0.2% Ce-doped SiOdTiO2 fibers exhibited higher photocatalytic activity than industrial Degussa P25 and the samples doped with only Ce or SIO2. The reasons for improving the photocatalytic activity were also discussed. Several operational parameters were studied, which showed that the photocatalytic efficiency of MB was influenced by parameters such as the initial dye concentration, the initial pH, inorganic anions, and so on. In addition, the influences of an electron acceptor and a radical scavenger suggested that OH was the dominant photooxidant during the photocatalytic process. The reuse evaluation of the fibers indicated that their photocatalytic activity had good stability.

关键词： photocatalysis SiO2/TiO2 cerium nanostructured fibers Methylene Blue

胃腔内注入生理盐水辅助超声引导下经皮胃造瘘

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中国介入影像与治疗学 2024年第3期21卷 185-186页

作者：刘扬何俊峰熊睿石包圣李志远王军内蒙古科技大学包头医学院第一附属医院超声科内蒙古包头014010

肠内营养支持是维持长期无法经口进食患者有效营养的重要手段,不仅能提供代谢能量来源,还可防止肠道菌群移位^([1])。经皮胃造瘘操作简单、创伤小,已成为实施肠内营养支持的重要方法^([2]),但难以用于无法经口于内镜下行造瘘或病情较重... 详细信息

肠内营养支持是维持长期无法经口进食患者有效营养的重要手段,不仅能提供代谢能量来源,还可防止肠道菌群移位^([1])。经皮胃造瘘操作简单、创伤小,已成为实施肠内营养支持的重要方法^([2]),但难以用于无法经口于内镜下行造瘘或病情较重不便于移动者。本研究观察胃腔内注入生理盐水用于辅助超声引导下经皮穿刺胃造瘘的效果。

关键词：胃造口术超声检查介入性

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Data quality issues for synchrophasor applications Part Ⅱ:problem formulation and potential solutions

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Journal of Modern Power Systems and Clean Energy 2016年第3期4卷 353-361页

作者： Can HUANG Fangxing LI Lingwei zhan Yao XU Qinran HU Dao ZHOU Yilu liu Department of Electrical Engineering and Computer Science The University of TennesseeKnoxvilleTN 37996USA

This work investigates the data quality issue for synchrophasor applications, and pays particular attention to synchronization signal loss and synchrophasor data loss events. First, the historical synchronization signal loss events are analyzed and the potential reasons and solutions are discussed. Then, the scenario of a small amount of synchrophasor data loss is studied and a Lagrange interpolating polynomial method is used to adaptively estimate the incomplete and missing data. The performance of proposed method is demonstrated with simulation ***, the proposed method considers the trade-off between the estimation accuracy and the hardware cost,and could be efficiently employed in reality.

关键词： GPS loss Synchronization signal loss Synchrophasor data loss Estimation Forecasting