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Training load characteristics and injury and illness risk identification in elite youth ski racing:A prospective study

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Journal of Sport and Health Science 2021年第2期10卷 230-236页

作者： Carolin Hildebrandt Renate Oberhoffer Christian Raschner Erich Muller Christian Fink lisa Steidl-Muller Department of Sport Science University of InnsbruckInnsbruck 6020Austria Department of Sport and Health Science Preventative PediatricsTechnical University of MunichMunich 80992Germany Department of Sport Science and Kinesiology University of SalzburgSalzburg 5400Austria GelenkpunktSports and Joint Surgery Innsbruck 6020Austria

Purpose:The study aimed to investigate the role of training load characteristics and injury and illness risk in youth ski ***:The training load characteristics as well as traumatic injuries,overuse injuries,and illnesses of 91 elite youth ski racers(age=12.1±1.3 years,mean±SD)were prospectively recorded over a period of 1 season by using a sport-specific online *** linear regression analyses were performed to monitor the influence of training load on injuries and *** in mean training load characteristics between preseason,in-season,and post-season were calculated using multivariate analyses of ***:Differences were discovered in the number of weekly training sessions(p=0.005)between pre-season(4.97±1.57)and post-season(3.24±0.71),in the mean training volume(p=0.022)between in-season(865.8±197.8 min)and post-season(497.0±225.5 min)and in the mean weekly training intensity(Index)(p=0.012)between in-season(11.7±1.8)and post-season(8.9±1.7).A total of 185 medical problems were reported(41 traumatic injuries,12 overuse injuries,and 132 illnesses).The weekly training volume and training intensity was not a significant risk factor for injuries(p>0.05).Training intensity was found to be a significant risk factor for illnesses in the same week(β=0.348;p=0.044;R^(2)=0.121)and training volume represents a risk factor for illnesses in the following week(β=0.397;p=0.027;R^(2)=0.157).Conclusion:A higher training intensity and volume were associated with increased illnesses,but not with a higher risk of *** training and ensuring appropriate progression of training load between weeks may decrease incidents of illness in-season.

关键词： Health problems Injury and illness prevention Training load Youth ski racing

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happiness is 500 ways to be the moment

happiness is 500 ways to be the moment

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作者： lisa Swerling & Ralph Lazar.

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Focal mechanism study of north Potwar deformed zone, Pakistan

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Acta Seismologica Sinica(English Edition) 2004年第3期17卷 255-261页

作者： Mona lisa Shahid A Khan Azam A Khwaja Department of Earth Sciences Quaid-I-Azam University Islamabad 45320 Pakistan Microseismic Studies Program MSSP Nilore 45650 Pakistan Department of Earth Sciences Quaid-I-Azam University Islamabad 45320 Pakistan

Northern Potwar Deformed Zone (NPDZ) is a part of the foreland zone of NW Himalayan folds and thrust belt. Seismicity map has been prepared for this region, which appears to be less active as compared with adjacent re-gions with apparently no distinct pattern or relationship with surface structures. Focal mechanism solutions of 4 events, for which required parameters are available, indicate left-lateral strike- slip faulting for 3 events and thrust-ing for one event. P-axes orientations are in NW-SE and NE-SW. Basement is most likely involved in the ongoing deformation.

关键词： focal mechanism seismicity northern Pakistan

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Antithrombotic therapy in patients with COVID-19:indications,pharmacotherapy and controversy

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Stroke & Vascular Neurology 2023年第4期8卷 263-265页

作者： David Wang Christopher Leo Liping Liu Li Huang lisa Huang Yun Lu Department of Neurology Petznick Stroke CenterBarrow Neurological InstitutePhoenixArizonaUSA Department of Medicine/Division of General Internal Medicine/Hospital Medicine Duke UniversityDurhamNorth CarolinaUSA Neurosurgical Intensive Care Unit(NICU) Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases BeijingChina Doctors Medical Center ModestoCaliforniaUSA Chesapeake Regional Medical Center ChesapeakeVirginiaUSA Hennepin Healthcare System and the University of Minnesota MinneapolisMinnesotaUSA

Hypercoagulability associated with COVID-19 infection increases risks for either venous or arterial thrombotic events(ATEs)or both.1 For hospitalised patients with COVID-19,the incidence of venous thromboembolism(VTE)was 4.5%2;the rate among patients with crit-ical illness was 27.9%as compared with those not critically ill(7.1%).The exact mechanism of COVID-19-related thrombotic events is ***,it may partially be related to Virchow triad:alternation of blood flow(stasis),vascular endothelial injury by SARS-CoV 2 virus and alteration of the constituents of the blood including inherited or acquired hypercoagulable ***,it is a challenge to evaluate the thromboembolic risk,select an appropriate antithrombotic agent and decide on the doses and duration of therapy in these *** international and American societies have published clinical guidelines that reviewed evaluation of coagulation abnormalities in patients with COVID-19.3-6 To balance the risk of bleeding and preventing or treating thromboembolic events,a simplified practical summarisation is needed.

关键词： patients thrombotic doses

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Multigene phylogeny and taxonomy of the genus Melanconiella(Diaporthales)

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Fungal Diversity 2012年第6期57卷 1-44页

作者： Hermann Voglmayr Amy Y.Rossman lisa A.Castlebury Walter M.Jaklitsch Department of Systematic and Evolutionary Botany Faculty Centre of BiodiversityUniversity of ViennaRennweg 141030WienAustria Systematic Mycology&Microbiology Laboratory USDAAgricultural Research ServiceB010A10300 Baltimore AveBeltsvilleMD 20705USA

Molecular phylogenetic analyses of LSU rDNA demonstrate monophyly of the genus Melanconiella,and its status as a genus distinct from Melanconis is *** of macro-and microscopic morphology,pure cultures and phylogenetic analyses of partial SSU-ITS-LSU rDNA,tef1 and rpb2 sequences revealed 13 distinct species of Melanconiella,six of which are described as new(***,***,***,***,***,***).Melanconiella hyperopta *** is described as a new *** carpinicola,***,***,*** and *** are formally combined into *** name Melanconiella chrysostroma is excluded from Melanconiella,as it is an obligate synonym of Wuestneia *** type of Melanconiella is confirmed as *** species are lecto-and/or epitypified.A key to all treated species ofMelanconiella is provided,and the circumscriptions of the genera Melanconis and Melanconiella are *** Melanconiella species revealed by molecular phylogenetic analyses can be well characterised by a suite of morphological traits including ascospore shape,length and width,colour,absence/presence and shape of appendages and the ***-teleomorph connections were confirmed by pure culture and DNA data,revealing the presence of a single melanconium-or discosporina-like anamorph for each *** growth was found to be characteristic of the respective *** is shown to be confined to the host family Betulaceae,and all species are found to be highly host-specific,mostly confined to a single host *** biodiversity ofMelanconiella was determined to be centred on the genus Carpinus with nine species,five of which have been confirmed on *** appears to be the geographic centre of Melanconiella biodiversity.

关键词： High diversity Host specificity Melanconidaceae Molecular phylogeny New species Pathogen Systematics

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Conducting health policy analysis in primary care research: turning clinical ideas into action

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Family Medicine and Community Health 2019年第2期7卷 53-59页

作者： Alina Engelman Ben Case lisa Meeks Michael D Fetters Health Sciences California State UniversityEast BayHaywardCaliforniaUSA Department of Family Medicine University of MichiganAnn ArborMichiganUSA Family Medicine University of MichiganAnn ArborMichiganUSA

Healthcare guidelines play a prominent role in the daytoday practice of primary care providers,and health policy research leads to the formation of these *** policy research is the multidisciplinary approach to public policy explaining the interaction between health institutions,special interests and theoretical *** this article,we demonstrate how primary care providers can conduct high-impact health policy research using Eugene Bardach’s eightfold policy analysis framework in a primary care *** a medical case,a woman with a history of total hysterectomy had scheduled a visit for a Papanicolaou(Pap)smear screening test as part of a well-woman health check-up with a family medicine *** recommendations on Pap smear screening after total hysterectomy sparked an investigation using the US Preventive Services Task Force criteria for conducting a health policy *** illustrate broadly how clinical care dilemmas can be examined by using Bardach’s broadly applicable health policy framework in order to inform meaningful policy ***’s framework includes(1)defining the problem,(2)assembling evidence,(3)constructing alternatives,(4)selecting criteria,(5)projecting outcomes,(6)confronting trade-offs,(7)decision-making and(8)sharing the results of the *** policy analysis demonstrated insufficient evidence to recommend Pap test screening after hysterectomy and the findings contributed to national *** following Bardach’s steps,primary care researchers have a feasible and powerful tool for conducting meaningful health policy research and analysis that can influence clinical practice.

关键词： policy meaningful conducting

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Efficacy and safety of tofacitinib for treatment of rheumatoid arthritis

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World Journal of Orthopedics 2014年第4期5卷 504-511页

作者： lisa M Lundquist Sabrina W Cole Martha L Sikes College of Health Professions Mercer University Atlanta GA 30341 United States School of Pharmacy Wingate University Wingate NC 28174 United States

Tofacitinib is the first in a new class of nonbiologic disease-modifying antirheumatic drugs(DMARDs), a targeted, synthetic DMARD, approved for the treatment of rheumatoid arthritis(RA) as monotherapy or in combination with methotrexate or other non-biologic DMARD. Tofacitinib, an orally administered Janus kinase(JAK) inhibitor, decreases T-cell activation, pro-inflammatory cytokine production, and cytokine signaling by inhibiting binding of type Ⅰcytokine receptors family and γ-chain cytokines to paired JAK1/JAK3 receptors. The net effect of tofacitinb's mechanism of action is decreased synovial inflammation and structural joint damage in RA patients. To date, six phase 3 trials have been conducted to evaluate the safety and efficacy of tofacitinib under the oral rheumatoid arthritis triaL s(ORAL) series. This review describes the pharmacology of the novel agent, tofacitinib, and details the safety and efficacy data of the ORAL trials.

关键词： Tofacitinib Rheumatoid arthritis Janus kinase inhibitor

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Trends in maternal body mass index in Northern Ireland:a cross-sectional and longitudinal study

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Family Medicine and Community Health 2021年第4期9卷 20-30,I0003-I0012页

作者： lisa Kent Christopher Cardwell Ian Young Kelly-Ann Eastwood Administrative Data Research Centre Northern Ireland Centre for Public HealthQueen's University BelfastBelfastUK Institute of Clinical Science Block BCentre for Public HealthQueen's University BelfastBelfastUK Fetal Medicine Unit University Hospitals Bristol and Weston NHS Foundation TrustBristolUK

Objectives Explore(1)associations between maternal body mass index(BMI),demographic and clinical characteristics,(2)longitudinal trends in BMI,(3)geographical distributions in prevalence of maternal overweight and *** Retrospective population-based *** Linked,anonymised,routinely collected healthcare data and official statistics from Northern *** All pregnancies in Northern Ireland(2011-2017)with BMI measured at≤16 weeks *** Analysis of variance andχ^(2)tests were used to explore *** linear regression was used to explore longitudinal trends and spatial visualisation illustrated geographical *** outcomes are prevalence of overweight(BMI≥25 kg/m^(2))and obesity(BMI≥30 kg/m^(2)).Results 152961 singleton and 2362 multiple pregnancies were included.A high prevalence of maternal overweight and obesity in Northern Ireland is apparent(singleton:52.4%;multiple:48.3%)and is *** was positively associated with older age,larger numbers of previous pregnancies and unplanned pregnancy(p25 kg/m^(2)is increasing over time in Northern *** are entering pregnancy with additional comorbidities likely to impact their life course beyond *** highlights the need for prioritisation of preconception and inter-pregnancy support for management of weight and

关键词： routine index category

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Lip rejuvenation and filler complications in the perioral region

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Plastic and Aesthetic Research 2022年第1期9卷 413-419页

作者： Elizabeth H.Wick Erin Ostby lisa D.Grunebaum Department of Otolaryngology-Head and Neck Surgery University of MiamiMiamiFL 33136USA Department of Surgery Division of Otolaryngology-Head and Neck SurgeryUniversity of VermontBurlingtonVT 05401USA

Lip and perioral augmentation procedures have become increasingly popular over the last two decades due to cultural trends,emphasizing youth and *** understanding of lip anatomy and aesthetics has traditionally formed the basis for successful ***,as new technology becomes available,patient standards have increased,requiring an intricate understanding of filler properties and the advantages of different technical *** chapter touches on pertinent anatomy and aesthetics of perioral *** also provides an overview of the properties of the fillers currently available in the United States marketplace for perioral *** technique and materials currently favored by the senior author are described in greater ***,the chapter will overview potential complications and recommended management.

关键词： Hyaluronic acid filler lip augmentation perioral augmentation rheology

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Capacities in Facing Natural Hazards: A Small Island Perspective

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International Journal of Disaster Risk Science 2014年第4期5卷 247-264页

作者： Mercy M.F.Rampengan Agni Klintuni Boedhihartono lisa Law J.C.Gaillard Jeffrey Sayer School of Earth and Environmental Sciences James Cook UniversityQueensland 4870Australia School of Environment The University of AucklandAuckland 1142New Zealand

Isolated communities on small islands are often characterized as vulnerable and marginalized. We studied the recent history of Laingpatehi, a village on Ruang Island off the north coast of Sulawesi, Indonesia to show that the marginalization-vulnerability nexus can be offset by capacity and social cohesion to enable sustainable livelihoods. The island has been impacted by volcanic eruptions,earthquakes, and competition for marine resources from mainland-based fishermen. The community has shown a remarkable ability to cope and prosper in the face of a series of external hazards. We used a sustainable livelihoods approach to identify the assets that enabled the villagers to cope. Strong social cohesion was central to the ability to organize the community and confront hazards. A diversified livelihood strategy drawing on the small island environment and its coastal and marine resources, income generating activities in a distant satellite village, and significant remittances from employment in other parts of Indonesia underpinned people’s capacities to face *** assistance played a supporting role. The case of Laingpatehi demonstrates how remoteness, rather than being a source of vulnerability, can provide access to existing resources and facilitate innovation. Disaster risk reduction strategies should focus more on reinforcing these existing capacities to deal with hazards and less on physical protection and postdisaster responses.

关键词： Human and social resources Indonesia Livelihood diversity Natural hazards Remote marginal communities Small islands

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