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Preparation of Micro-Iron Ore Tailings by Wet-Grinding and Its Application in Sulphoaluminate Cement

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Journal of Renewable Materials 2022年第4期10卷 1007-1023页

作者： Yingchun Yang liqing chen Xingdong Sun Yuguang Mao College of Engineering Anhui Agricultural UniversityHefei230036China College of Civil Engineering Hunan UniversityChangsha410082China

Herein,micro iron ore tailings(micro-IOTs)were prepared by wet-grinding and applied to improve sulphoaluminate cement(SAC)performance.The physicochemical properties of micro-IOTs were investigated by particle size analysis,XRD,and XPS.The hydrates trait and the hydration mechanism of micro-IOTs-SAC composite were studied by XRD,TGA,MIP,and SEM.The results demonstrated that micro-IOTs with an average grain diameter of 517 nm could be obtained by wet-grinding.The setting time of SAC gradually decreased with increasing micro-IOTs content.By adding 2%micro-IOTs,the compressive strengths of SAC pastes were enhanced about 22%and 10%at 4 h and 28 d,respectively.Moreover,the addition of micro-IOTs accelerated ettringite precipitation and changed its morphology,resulting in early strength improvement of the binary system.And increased later strength by micro-IOTs was closely related to the high content of AH_(3),fine pore structure,and high hydration degree of SAC.The findings suggested one new approach to utilize iron ore tailings in cementbased materials.

关键词： Micro iron ore tailings sulphoaluminate cement ettringite compressive strength hydration process

Memory-assisted quantum accelerometer with multi-bandwidth

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Photonics Research 2022年第4期10卷 1022-1030页

作者： Zhifei Yu Bo Fang liqing chen Keye Zhang Chun-Hua Yuan Weiping Zhang State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200062China Shanghai Research Center for Quantum Sciences Shanghai 201315China School of Physics and Astronomy Shanghai Jiao Tong Universityand Tsung-Dao Lee InstituteShanghai 200240China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China

The accelerometer plays a crucial role in inertial navigation.The performance of conventional accelerometers such as lasers is usually limited by the sensing elements and shot noise limitation(SNL).Here,we propose an advanced development of an accelerometer based on atom–light quantum correlation,which is composed of a cold atomic ensemble,light beams,and an atomic vapor cell.The cold atomic ensemble,prepared in a magneto-optical trap and free-falling in a vacuum chamber,interacts with light beams to generate atom–light quantum correlation.The atomic vapor cell is used as both a memory element storing the correlated photons emitted from cold atoms and a bandwidth controller through the control of free evolution time.Instead of using a conventional sensing element,the proposed accelerometer employs interference between quantum-correlated atoms and light to measure acceleration.Sensitivity below SNL can be achieved due to atom–light quantum correlation,even in the presence of optical loss and atomic decoherence.Sensitivity can be achieved at the ng∕√Hz level,based on evaluation via practical experimental conditions.The present design has a number of significant advantages over conventional accelerometers such as SNL-broken sensitivity,broad bandwidth from a few hundred Hz to near MHz,and avoidance of the technical restrictions of conventional sensing elements.

关键词： quantum accelerometer atomic

2022 International Paper Technical Conference: A Preview

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Paper And Biomaterials 2022年第4期7卷 20-27页

作者： Yan Yang Zhenhua Liu liqing chen China National Pulp and Paper Research Institute Co. Ltd.Beijing100102China

This is a preview pertaining to the upcoming event of the 2022 International Paper Technical Conference.Herein we provide the condensation of twelve presentations which will be given by our honorable speakers.Conference themes comprise of status quo of supply of raw material,the newest dynamic trend of papermaking industry both in China and Brazil,eucalyptus pulp as a shining role in molded pulp,high-value utilization of biomass,the most concerned hotspot—carbon reduction,and existing problems challenging the application of paper-based materials in packaging market.From the source to the end product,we offer you the full view of paper industry in expound.

关键词： papermaking industry molded pulp biomass eucalyptus

Construction of a transposase accessible chromatin landscape reveals chromatin state of repeat elements and potential causal variant for complex traits in pigs

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Journal of Animal Science and Biotechnology 2023年第2期14卷 529-545页

作者： Tao Jiang Ziqi Ling Zhimin Zhou Xiaoyun chen liqing chen Sha Liu Yingchun Sun Jiawen Yang Bin Yang Jianzhen Huang Lusheng Huang State Key Laboratory of Pig Genetic Improvement and Production Technology Jiangxi Agricultural UniversityNanchang 330045China

Background:A comprehensive landscape of chromatin states for multiple mammalian tissues is essential for elucidating the molecular mechanism underlying regulatory variants on complex traits.However,the genome-wide chromatin accessibility has been only reported in limited tissue types in pigs.Results:Here we report a genome-wide landscape of chromatin accessibility of 20 tissues in two female pigs at ages of 6 months using ATAC-seq,and identified 557,273 merged peaks,which greatly expanded the pig regulatory ele-ment repository.We revealed tissue-specific regulatory elements which were associated with tissue-relevant biologi-cal functions.We identified both positive and negative significant correlations between the regulatory elements and gene transcripts,which showed distinct distributions in terms of their strength and distances from corresponding genes.We investigated the presence of transposable elements(TEs)in open chromatin regions across all tissues,these included identifications of porcine endogenous retroviruses(PERVs)exhibiting high accessibility in liver and homology of porcine specific virus sequences to universally accessible transposable elements.Furthermore,we prior-itized a potential causal variant for polyunsaturated fatty acid in the muscle.Conclusions:Our data provides a novel multi-tissues accessible chromatin landscape that serve as an important resource for interpreting regulatory sequences in tissue-specific and conserved biological functions,as well as regula-tory variants of loci associated with complex traits in pigs.

关键词： Chromatin accessibility Pig Tissue specific Transcriptome Transposable elements

Genetic dissection and genomic prediction for pork cuts and carcass morphology traits in pig

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Journal of Animal Science and Biotechnology 2023年第6期14卷 2345-2362页

作者： Lei Xie Jiangtao Qin Lin Rao Dengshuai Cui Xi Tang liqing chen Shijun Xiao Zhiyan Zhang Lusheng Huang State Key Laboratory for Pig Genetic Improvement and Production Technology Jiangxi Agricultural UniversityNanchang 330045China

Background As pre-cut and pre-packaged chilled meat becomes increasingly popular,integrating the carcasscutting process into the pig industry chain has become a trend.Identifying quantitative trait loci(QTLs)of pork cuts would facilitate the selection of pigs with a higher overall value.However,previous studies solely focused on evaluating the phenotypic and genetic parameters of pork cuts,neglecting the investigation of QTLs influencing these traits.This study involved 17 pork cuts and 12 morphology traits from 2,012 pigs across four populations genotyped using CC1 PorcineSNP50 BeadChips.Our aim was to identify QTLs and evaluate the accuracy of genomic estimated breed values(GEBVs)for pork cuts.Results We identified 14 QTLs and 112 QTLs for 17 pork cuts by GWAS using haplotype and imputation genotypes,respectively.Specifically,we found that HMGA1,VRTN and BMP2 were associated with body length and weight.Subsequent analysis revealed that HMGA1 primarily affects the size of fore leg bones,VRTN primarily affects the number of vertebrates,and BMP2 primarily affects the length of vertebrae and the size of hind leg bones.The prediction accuracy was defined as the correlation between the adjusted phenotype and GEBVs in the validation population,divided by the square root of the trait’s heritability.The prediction accuracy of GEBVs for pork cuts varied from 0.342 to 0.693.Notably,ribs,boneless picnic shoulder,tenderloin,hind leg bones,and scapula bones exhibited prediction accuracies exceeding 0.600.Employing better models,increasing marker density through genotype imputation,and pre-selecting markers significantly improved the prediction accuracy of GEBVs.Conclusions We performed the first study to dissect the genetic mechanism of pork cuts and identified a large number of significant QTLs and potential candidate genes.These findings carry significant implications for the breeding of pork cuts through marker-assisted and genomic selection.Additionally,we have constructed the first reference populations for genomic sele

关键词： Carcass morphology traits Genomic selection Genotype imputation GWAS Pork cuts

Optimizing Raman quantum memory with dynamic phase

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Science China(Information Sciences) 2023年第8期66卷 61-71页

作者： Sheng MING Jinxian GUO Yuan WU Guzhi BAO Shuhe WU Minwei SHI liqing chen Weiping ZHANG School of Physics and Astronomy and Tsung-Dao Lee Institute Shanghai Jiao Tong University Shanghai Research Center for Quantum Sciences State Key Laboratory of Precision Spectroscopy Quantum Institute of Atom and Light Department of PhysicsEast China Normal University Collaborative Innovation Center of Extreme Optics Shanxi University Shanghai Branch Hefei National Laboratory

Optical quantum memory is a key component of emerging quantum technologies and applications. One of the most promising protocols, far-off-resonant Raman memory, is still beset by its efficiency.Until now, the only effective method for enhancing its efficiency in experiments has been the intensity modulation method on the control field, while the experimental demonstrations still fail to meet the theoretical expectation. In this study, we experimentally demonstrate how to optimize the Raman quantum memory process using a new method called phase modulation; 52.7% total memory efficiency is realized by applying a phase modulation on the control field with a near-square intensity waveform of the control field, thereby resulting in an increase in efficiency of 13.3% compared to the best case of no phase modulation. Additionally, a hybrid method, combining the phase and intensity modulations, is demonstrated with 87.3% memory efficiency. Such high-efficiency results in 99.0% unconditional fidelity even at near single photon level. The unconditional fidelity is always higher than that of the intensity method as the input photon number of the signal increases and can still beat the nonclone limit, even at 128.1 photons/pulse. Our phase modulation method has great potential applications in quantum information processing due to the advantages of low experimental requirements but an additional degree of freedom and high performance, especially for the high speed and high photon number state manipulation.

关键词： quantum information quantum optics quantum communication quantum memory Raman scattering

Research advances in peptide-drug conjugates

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药学学报:英文版 2023年第9期13卷 3659-3677页

作者： Liming Gong Heming Zhao Yanhong Liu Hao Wu Chao Liu Shuangyan Chang liqing chen Mingji Jin Qiming Wang Zhonggao Gao Wei Huang State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050China Beijing Key Laboratory of Drug Delivery Technology and Novel Formulations Department of PharmaceuticsInstitute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050China Department of Pharmacy Yanbian UniversityYanji 133000China

Peptide-drug conjugates(PDCs)are drug delivery systems consisting of a drug covalently coupled to a multifunctional peptide via a cleavable linker.As an emerging prodrug strategy,PDCs not only preserve the function and bioactivity of the peptides but also release the drugs responsively with the cleavable property of the linkers.Given the ability to significantly improve the circulation stability and targeting of drugs in vivo and reduce the toxic side effects of drugs,PDCs have already been extensively applied in drug delivery.Herein,we review the types and mechanisms of peptides,linkers and drugs used to construct PDCs,and summarize the clinical applications and challenges of PDC drugs.

关键词： Peptide-drug conjugates Peptides Linkers Drug delivery systems Prodrug strategy

Microstructure and abrasive wear resistance of an alloyed ductile iron subjected to deep cryogenic and austempering treatments

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Journal of Materials Science & Technology 2017年第12期33卷 1549-1554页

作者： Junjun Cui liqing chen State Key Laboratory of Rolling and Automation Northeastern University College of Mechanical and Vehicle Engineering Shenyang Institute of Technology

To further improve the mechanical performance of a new alloyed austempered ductile iron（ADI）, deep cryogenic treatment（DCT） has been adopted to investigate the effect of DCT time on the microstructure and mechanical behaviors of the alloyed ADI Fe-3.55 C-1.97 Si-3.79 Ni-0.71 Cu-0.92 Mo-0.64 Cr-0.36 Mn-0.30 V（in wt.%）. With increasing the DCT time, more austenite transformed to martensite and very fine carbides precipitated in martensite in the extended period of DCT. The amount of austenite decreased in alloyed ductile irons, while that of martensite and carbide precipitation increased. The alloyed ADI after DCT for 6 h had the highest hardness and compressive strength, which can be attributed to the formation of more plate-like martensite and the finely precipitated carbides. There was a gradual decrease in hardness and compressive strength with increasing the DCT time to 12 h because of the dissolution of M3 C carbide. After tempering, there was a decrease in mechanical properties compared to the direct DCT sample, which was caused by the occurrence of Ostwald ripening of precipitated carbides. The optimum wear resistance was achieved for the alloyed ADI after DCT for 6 h. The wear mechanism of the alloyed ADI in associating with DCT is mainly consisted of micro-cutting wear and some plastic deformation wear.

关键词： Alloyed ductile iron Austempering Deep cryogenic treatment （DCT） Microstructure Mechanical properties

Processing,Microstructures,and Mechanical Properties of Magnesium Matrix Composites:A Review

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Acta Metallurgica Sinica(English Letters) 2014年第5期27卷 762-774页

作者： liqing chen Yantao Yao State Key Laboratory of Rolling and Automation Northeastern University

In the last two decades, light-weight magnesium matrix composites have been the hot issue of material field due to their excellent mechanical and physical properties, e.g., high-specific strength and modulus, good wear resistance, and damping capacity. As compared with aluminum matrix composites, magnesium matrix composites have merit in their specific weight and have wide applications in aerospace and aeronautical fields. Generally, the processing techniques for magnesium matrix composites can be categorized as conventional and special processing routes. In recent years, as a special processing route, metal melt infiltration into porous ceramic preform featured by its low cost and availability of high-volume fraction of reinforced ceramics have been receiving much attention. Thus, in this review, one emphasis was put on the description of this processing technique in association with the means to obtain good wettability, the prerequisite for this kind of processing method. Based on the recognized fact that there exist clean interface and bonding ability between ceramics and matrix metal, in-situ reaction synthesis is usually utilized to fabricate magnesium matrix composites. Therefore, the interfacial feature was also reviewed for the in-situ reaction synthesis. Characterizations of microstructures and various mechanical-physical properties were finally summarized for magnesium matrix composites including tensile response, wear resistance, creep behavior, and damping capacity.

关键词： Magnesium matrix composites Processing Microstructure Mechanical properties Wettability Interface