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Particuology 2020年第2期18卷 95-104页

作者： liping wei Guodong Jiang Haipeng Teng Jun Hu Jianbo Zhu School of Chemical Engineering Northwest UniversityChemical Engineering Research Center of the Ministry of Education for Advanced Use Technology of Shanbei Energyand Shaanxi Research Center of Engineering Technology for Clean Coal ConversionXi'an 710069ShaanxiChina

A particle-particle(p-p)drag model is extended to cohesive particle flow by introducing solid surface energy to characterize cohesive collision energy *** effects of the proportion of cohesive particles on the mixing of binary particles were numerically investigated with the use of a Eulerian multiphase flow model incorporating the p-p drag *** bed expansion,mixing,and segregation of Geldart-A and C particles were simulated with varying superficial velocities and Geldart-C particle proportions,from which we found that the p-p drag model can reasonably predict bed expansion of binary *** segregation types of jetsam-mixture-flotsam and mixture-flotsam processes were observed during the fluidization processes for the Geldart-A and C binary particle *** mixing processes of the binary particle system can be divided into three scales:macro-scale mixing,meso-scale mixing,and micro-scale *** a constant superficial velocity the optimal mixing was observed for a certain cohesive particle proportion.

关键词： Fluidization Cohesive particle Particle-particle drag model Mixing index Binary particles

Benthic microbial biogeography along the continental shelf shaped by substrates from the Changjiang River plume

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Acta Oceanologica Sinica 2022年第1期41卷 118-131页

作者： Yongjun wei Shan Jiang Lingmin Tian liping wei Jie Jin Juan Severino Pino Ibanhez Yan Chang Xiaodao wei Ying Wu Key Laboratory of Advanced Drug Preparation Technologies of Ministry of Education School of Pharmaceutical SciencesZhengzhou UniversityZhengzhou 450001China State Key Laboratory of Estuarine and Coastal Research East China Normal UniversityShanghai 200241China Department of Food Science and Engineering Jinan UniversityGuangzhou 510632China Key Laboratory of Vegetation Restoration and Management of Degraded Ecosystems South China Botanical GardenChinese Academy of SciencesGuangzhou 510650China School of Natural Sciences Trinity College DublinDublin 2Ireland Instituto de Investigacions Marinas Consejo Superior de Investigaciones CientificasVigo 36208Spain Institute of Eco-Chongming East China Normal UniversityShanghai 202162China

Coastal zones are active reactors of continental material including that transported by rivers via a series of microbiota-mediated reactions. Nevertheless, current knowledge of the ecology and functioning of the microbiota in coastal areas affected by large riverine inputs remains insufficient on a global scale. Here, an investigation on sediment microbial composition, including taxonomy and metabolic network, as well as their relationship with major benthic reaction substrates, namely carbon, nitrogen, sulphur and phosphorus, was conducted in the continental shelf affected by the spread of the Changjiang River plume. Surface sediment samples(48 samples)were collected during March 2018, obtaining a mean Operational Taxonomic Units(OTUs) number of 3 ***, Acidobacteria and Actinobacteria were abundant phyla in the studied sediments. Bray-Curtis distance analysis classified the 48 samples into 4 clusters(MG1 to MG4) at the phylum-level. MG1 and MG2 are found near the river mouth, receiving substantial land-derived particles from the Changjiang River ***-attached microbes may be settled in these regions and influenced the observed sediment microbial diversity and biomass, e.g., increased Crenarchaeota relative abundance. The relative enrichment of these two groups in heterotrophic microbes further suggests a reliance of benthic microbiota on substrates with terrestrial origin, particularly specialized on processing sulphur-rich substrates. Regions MG3 and MG4 are located in the outer margin of the area affected by the Changjiang River plume, mainly fed by settling pelagic particles from phytoplankton. Compared to MG1 and MG2, a significant increase in the abundance of Thaumarcheota(phylumlevel) and Nitrosopumilus(genus-level) was found in MG3, suggesting nitrogen-related transformations as the key reactions to sustain microbial metabolism in this region. Coupled with the identified variations in the taxonomic composition, significant differenc

关键词： benthic microbiota biogeography benthic substrate Changjiang River plume East China Sea Yellow Sea

Numerical simulation of water-slag elbow erosion-inhibiting by regulating the slag injection position with a novel preceding rotating sheet structure

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Particuology 2024年第7期90卷 323-339页

作者： Fopeng Wen Liuyun Xu Yixiang Chen Zhaofu Deng Shen Zhang Wenming Song Yuge Li liping wei School of Chemical Engineering Northwest UniversityXi’an710069China School of Chemistry and Chemical Engineering Yan'an UniversityYan'an716000China Machinery Industry Shanghai Lanya Petrochemical Equipment Inspection Institute Co. Ltd.Shanghai201518China The Research Center of Chemical Engineering Applying Technology for Resource of Shaanxi Xi’an710069China

The elbow erosion seriously jeopardizes the safe and stable operation of water–slag discharge pipeline of the coal gasification *** work simulated water–slag elbow characteristics with various slag injection positions by simulating five simplified and representative erosion categories,including A-type horizontal-vertical elbow with an upstream flow,B-type horizontal-vertical elbow with a downstream flow,C-type vertical-horizontal elbow with an upstream flow,D-type vertical-horizontal elbow with a downstream flow and E-type horizontal-horizontal *** with the C/D-type elbow,where particles were injected uniformly,the A-type elbow and E-type elbow were found to increase erosion rate,while the B-type elbow decreases erosion *** interesting discovery is that the elbow erosion rate is relatively low for small particles when particles are injected from the middle and bottom positions of the inlet section of the *** on the observation,a novel preceding rotating sheet structure was developed to regulate the particle injection *** shows an excellent anti-erosion performance by reducing the maximum erosion rate of particles with diameters of 50,100,and 200μm by 23%,35%,and 43%,respectively.

关键词： Erosion Slag-water Uneven particles Elbow pipe Erosion inhibition Preceding rotating sheet structure

Candidate Mycobacterium tuberculosis genes targeted by human microRNAs

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Protein & Cell 2010年第5期1卷 419-421页

作者： weiRui Guo Jiong-Tang Li Xiao Pan liping wei Jane Y.Wu Institute of Biophysics Chinese Academy of Sciences15 Datun RoadBeijing 100101China Center for Bioinformatics National Laboratory of Protein Engineering and Plant Genetic EngineeringCollege of Life SciencesPeking UniversityBeijing 100871China Department of Neurology Center for Genetic MedicineLurie Comprehensive Cancer CenterNorthwestern University Feinberg School of Medicine303 E.SuperiorChicagoIL 60611USA Graduate University of Chinese Academy of Sciences 19A Yuquan RoadBeijing 100039China

Tuberculosis(TB)remains a major health issue,causing approximately three million deaths every year(Pelicic et al.,1998).Identified by Robert Koch in 1882,Mycobacterium tuberculosis(***),the causative agent for tuberculosis,remains one of the most enigmatic *** interactions between *** and its environment have been extensively ***,our knowledge about potential ***-host interaction at the RNA level is still very *** we present our preliminary finding that suggests possible interactions of human miRNAs with *** transcripts and speculate possible roles of human miRNAs in regulating *** interactions.

关键词： tuberculosis al. targeted

MosaicBase:A Knowledgebase of Postzygotic Mosaic Variants in Noncancer Disease-related and Healthy Human Individuals

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Genomics, Proteomics & Bioinformatics 2020年第2期18卷 140-149页

作者： Xiaoxu Yang Changhong Yang Xianing Zheng Luoxing Xiong Yutian Tao Meng Wang Adam Yongxin Ye Qixi Wu Yanmei Dou Junyu Luo liping wei August Yue Huang Center for Bioinformatics State Key Laboratory of Protein and Plant Gene ResearchSchool of Life SciencesPeking UniversityBeijing 100871China Department of Bioinformatics Chongqing Medical UniversityChongqing 400016China College of Life Sciences Beijing Normal UniversityBeijing 100875China National Institute of Biological Sciences Beijing 102206China Peking-Tsinghua Center for Life Sciences(CLS) Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100730China School of Life Sciences Peking UniversityBeijing 100871China

Mosaic variants resulting from postzygotic mutations are prevalent in the human genome and play important roles in human ***,except for cancer-related variants,there is no collection of postzygotic mosaic variants in noncancer disease-related and healthy ***,we present MosaicBase,a comprehensive database that includes 6698 mosaic variants related to 266 noncancer diseases and 27,991 mosaic variants identified in 422 healthy *** and phenotypic information of each variant was manually extracted and curated from 383 *** supports the query of variants with Online Mendelian Inheritance in Man(OMIM)entries,genomic coordinates,gene symbols,or Entrez *** also provide an integrated genome browser for users to easily access mosaic variants and their related annotations for any genomic *** analyzing the variants collected in MosaicBase,we find that mosaic variants that directly contribute to disease phenotype show features distinct from those of variants in individuals with mild or no phenotypes,in terms of their genomic distribution,mutation signatures,and fraction of mutant *** will not only assist clinicians in genetic counseling and diagnosis but also provide a useful resource to understand the genomic baseline of postzygotic mutations in the general human *** is publicly available at http://***/or http://49.***.21.8:8000.

关键词： Postzygotic Mosaicism Noncancer Mutation MosaicBase

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西藏不同种源光核桃仁脂肪酸组成分析

食品科学 2016年第22期37卷 107-111页

作者：王伟魏丽萍西藏农牧学院资源与环境学院西藏林芝860000

采用溶剂回流法及气相色谱法,分析全西藏范围内9个种源的光核桃仁出油率、油脂种类及相对含量特征。结果表明,9个种源的光核桃仁出油率差异显著,均值为44.96%;光核桃油中不饱和脂肪酸相对含量极高,均值为90.901%,主要由油酸和亚油酸组成... 详细信息

采用溶剂回流法及气相色谱法,分析全西藏范围内9个种源的光核桃仁出油率、油脂种类及相对含量特征。结果表明,9个种源的光核桃仁出油率差异显著,均值为44.96%;光核桃油中不饱和脂肪酸相对含量极高,均值为90.901%,主要由油酸和亚油酸组成,油酸相对含量的变化范围为45.280%-71.360%,最高值为芒康县的光核桃;亚油酸相对含量的变化范围为18.010%-44.340%,最高值为亚东县光核桃;饱和脂肪酸相对含量均值为9.099%,主要成分为棕榈酸和硬脂酸,棕榈酸相对含量的变化范围为5.829%-7.354%,最高值为亚东县光核桃;硬脂酸相对含量的变化范围为1.600%-3.034%,最高值为察隅县光核桃。基于11种脂肪酸相对含量特征的聚类分析表明,米林县、左贡县、波密县、八宿县光核桃仁油脂相对含量特征相近,芒康县则与其他种源光核桃油脂特征差异较大。

关键词：西藏光核桃仁出油率脂肪酸组成

Secure SSL/TLS Communication System Based on Quantum Keys

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ZTE Communications 2024年第3期22卷 106-115页

作者： WANG Jigang LU Yuqian wei liping JIANG Xinzao ZHANG Han State Key Laboratory of Mobile Network and Mobile Multimedia Shenzhen 518055China Department of Cyberspace Security ZTE CorporationShenzhen 518057China School of Cyber Science and Engineering Southeast UniversityNanjing 211102China

Secure Sockets Layer(SSL)and Transport Layer Security(TLS)protocols facilitates a secure framework for identity authentication,data encryption,and message integrity ***,with the recent development in quantum computing technology,the security of conventional key-based SSL/TLS protocols faces *** this paper,we propose a scheme by integrating the quantum key into the SSL/TLS ***,the application of post-quantum algorithms is used to enhance and complement the existing encryption *** results show that the proposed SSL/TLS communication system based on quantum keys exhibits high performance in latency and ***,the proposed system showcases good resilience against quantum attacks.

关键词： SSL/TLS protocols quantum key post-quantum cryptography

Endovascular therapy for Acute ischemic Stroke Trial (EAST): study protocol for a prospective, multicentre control trial in China

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Stroke & Vascular Neurology 2016年第2期1卷 44-51页

作者： Zhongrong Miao Xiaochuan Huo Feng Gao Xiaoling Liao Chunjuan Wang Ya Peng Yibin Cao Shengli Chen Meng Zhang Changchun Jiang Xiaoxiang Peng Cunfeng Song liping wei Qiyi Zhu Zaiyu Guo Li Liu Hang Lin Hua Yang wei Wu Hui Liang Anding Xu Kangning Chen Xingquan Zhao Yuesong Pan Hao Li liping Liu Yilong Wang Yongjun Wang EAST investigators Department of Interventional Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases BeijingChina Vascular Neurology Department of NeurologyBeijing Tiantan HospitalCapital Medical UniversityBeijingChina Department of Neurology Tiantan Clinical Trial and Research Center for StrokeBeijing Tiantan HospitalCapital Medical UniversityBeijingChina Center of Stroke Beijing Institute for Brain DisordersBeijingChina Department of Neurosurgery Changzhou No 1 People’s HospitalChangzhouChina Department of Neurology Tangshan Gongren HospitalTangshanChina Department of Neurology Chongqing Sanxia Central HospitalChongqingChina Department of Neurology Daping HospitalChongqingChina Department of Neurology Baotou Central HospitalBaotouChina Department of Neurology Hubei Zhongshan HospitalWuhanChina Department of Neurology Liaocheng Third People’s HospitalLiaochengChina Department of Neurology Luoyang Central Hospital affiliated to Zhengzhou UniversityChina Department of Neurology People’s Hospital of Linyi CityChina Department of Neurology Tianjin TEDA HospitalChina Department of Neurology Chifeng Municipal HospitalChina Department of Neurology Fuzhou PLA General HospitalChina Department of Neurology Affiliated Hospital of Guiyang Medical CollegeChina Department of Neurology Qilu Hospital of Shandong UniversityChina Department of Neurology Yantai Hill HospitalChina Department of Neurology The First Affiliated Hospital of Jinan UniversityChina Department of Neurology Xinan HospitalChina Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease BeijingChina Neuro-intensive Care Unit Department of NeurologyBeijing Tiantan HospitalCapital Medical UniversityBeijingChina 不详

Background and purpose:5 recent trials have shown the benefit of endovascular treatment for acute ischaemic stroke(AIS)due to large vessel occlusion of the anterior *** study aims to evaluate the safety and efficacy of Solitaire thrombectomy in patients with moderate-to-severe stroke in the Chinese population,which has a high prevalence of intracranial *** and analysis:This multicentre prospective control study will involve 17 stroke centres in China,and plans to recruit 150 patients in the intervention group,and 150 patients in the medical group,in which patients meet enrolment criteria but refuse *** with AIS due to large vessel occlusion indicated for treatment with Solitaire stent retriever within 12 hours of symptom onset,and who meet the inclusion and exclusion criteria,will be enrolled in this *** primary efficacy endpoint is functional independence as defined by a modified Rankin Scale(mRS)score≤2 at 90 days or by functional improvement as defined by mRS,using shift *** procedural efficacy endpoint is arterial recanalisation of the occluded target vessel measured by a modified Thrombolysis in Cerebral Infarction(mTICI)score equal or superior to 2b right following the use of the study *** primary safety endpoint is symptomatic intracranial haemorrhage(sICH)within 24±3 hours *** and dissemination:The protocol was approved by the Ethics Committee at the coordinating centre and by the local Institutional Review Board of each participating *** registration number:NCT02350283.

关键词： prospective centre occlusion

文种简化和规范化新思路——依据“宏观职能”确定文件制发主体的文种使用范围

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档案 2004年第5期 9-11页

作者：魏丽平四川大学公共管理学院

一文种,即为概括表明文书的特性与使用范围而赋予每种文书的统一、规范的名称.正确规范地选用文种对公文处理工作具有十分重要的意义.只有正确选用文种,公文写作才能实现规范化,文件才能得到及时妥善的处理,公文的严肃性、权威性和有效... 详细信息

一文种,即为概括表明文书的特性与使用范围而赋予每种文书的统一、规范的名称.正确规范地选用文种对公文处理工作具有十分重要的意义.只有正确选用文种,公文写作才能实现规范化,文件才能得到及时妥善的处理,公文的严肃性、权威性和有效性才能得到维护.目前,在实际工作中,文种的使用还存在不同程度的混乱.针对这一现象,不少学者提出了很多具有理论指导和实践意义的建议和设想,笔者认为其中最具代表性的观点主要有以下两种:

关键词：公文文种使用规范化宏观职能新思路使用范围《国家行政机关公文处理办法》档案价值档案学通讯社会组织处理条例

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双主体税制是我国税制的最优选择

厦门大学学报（哲学社会科学版） 1998年第4期48卷 92-95,111页

作者：魏立萍厦门大学财金系

税收制度，按照主体税种的不同，可以分为三种，一是以所得税为主体的税制，二是以流转税为主体的税制，三是以流转税和所得税为双主体的税制。我国税制模式的改革取向应是以流转税和所得税为双主体的税制。首先，双主体税制能保证国家... 详细信息

税收制度，按照主体税种的不同，可以分为三种，一是以所得税为主体的税制，二是以流转税为主体的税制，三是以流转税和所得税为双主体的税制。我国税制模式的改革取向应是以流转税和所得税为双主体的税制。首先，双主体税制能保证国家的财政收入，有利于政府职能的实现。第二，我国社会主义市场经济还不完善，必须加强流转税和所得税的双重调控功能。第三，双主体税制既实现了效率，又体现了公平；既发展了生产力，又缩小了收入差距。第四，西方发达国家的税制经历了从以流转税为主体到以所得税为主体，然后向二者融合的过程，这一过程启示了我国税制改革的方向。

关键词：税收制度主体税种所得税流转税双主体税收制