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Atmospheric correction for HY-1C CZI images using neural network in western Pacific region

Geo-Spatial Information Science 2022年第3期25卷 476-488页

作者： Jilin Men Jianqiang Liu Guangping Xia Tong Yue Ruqing Tong Liqiao Tian Kohei Arai linyu Wang State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan UniversityWuhanChina Ministry of Natural Resource of the People’s Republic of China National Satellite Ocean Application ServiceBeijingChina School of Remote Sensing and Information Engineering Wuhan UniversityWuhanChina Department of Information Science Saga UniversitySagaJapan Department of Urban Development Wuhan Land Containment and Reserve CenterWuhanChina

With a spatial resolution of 50 m,a revisit time of three days,and a swath of 950 km,the coastal zone imager(CZI)offers great potential in monitoring coastal zone *** atmo-spheric correction(AC)is needed to exploit the potential of quantitative ocean color ***,due to the band setting of CZI,the AC over coastal waters in the western Pacific region with complex optical properties cannot be realized *** research introduces a novel neural network(NN)AC algorithm for CZI data over coastal *** 100,000 match-ups of HY-1 C CZI-observed reflectance at the top-of-atmosphere and Operational Land Imager(OLI)-retrieved high-quality remote sensing reflectance(Rrs)at the CZI bands are built to train the NN *** reflectance data are obtained from the standard AC algorithm in the *** indicate that the distributions of the CZI retrieved Rrs were consistent with the quasi-synchronous OLI data,but the spatial information from the CZI is more ***,the accuracy of the CZI data for AC is evaluated using the multi-source in-situ *** further show that the NN-AC can successfully retrieve Rrs for CZI and the coefficients of determination in the blue,green,red,and near-infrared bands were 0.70,0.77,0.76,and 0.67,*** NN algorithm does not depend on shortwave-infrared bands and runs very fast once properly trained.

关键词： Haiyang-1C coastal zone imager(HY-1C CZI) atmospheric correction neural network coastal water remote sensing

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Progesterone treatment before experimental hypoxia-ischemia enhances the expression of glucose transporter proteins GLUT1 and GLUT3 in neonatal rats

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Neuroscience Bulletin 2013年第3期29卷 287-294页

作者： Xinjuan Li Hua Han Ruanling Hou linyu Wei Guohong Wang Chaokun Li Dongliang Li Department of Physiology and Neurobiology Xinxiang Medical University Department of Ultrasonic Diagnosis Central Hospital of Xinxiang City Henan Key Lab of Biological Psychiatry

Progesterone is an efficient candidate for treating stroke and traumatic brain damage. The current study was designed to investigate the effects of pro gesterone on glucose transporter proteins （GLUT1 and GLUT3） during hypoxicischemic injury in a neo natal rat model. We demonstrated strong staining for GLUT1 in the walls of blood vessels and GLUT3 im munoreactivity in hippocampal neurons after hypoxia ischemia. Hypoxiaischemia elevated GLUT1 and GLUT3 at both the mRNA and protein levels in the hippocampus, and pretreatment with progesterone （8 mg/kg） further enhanced their accumulation until 24 h after hypoxicischemic injury. These results showed that progesterone treatment induced the accumula tion of both GLUT1 and GLUT3 transporters, and an energycompensation mechanism may be involved in the neuroprotective effect of progesterone during hy poxicischemic injury after cerebral ischemic attacks.

关键词： hypoxic-ischemic injury progesterone GLUT1 GLUT3 stroke

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Simulation Study of the Control Strategy of a DC Inverter Heat Pump Using a DC Distribution Network

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Energy Engineering 2023年第6期120卷 1421-1444页

作者： Siwei Han Xianglong Li Wei Zhao linyu Wang Anqi Liang Shuang Zeng State Grid(Suzhou)City and Energy Research Institute SuzhouChina Electric Power Research Institute of State Grid Beijing Electric Power Company BeijingChina

Photovoltaics,energy storage,direct current and flexibility(PEDF)are important pillars of achievement on the path to manufacturing nearly zero energy buildings(NZEBs).HVAC systems,which are an important part of public buildings,play a key role in adapting to PDEF *** research studied the basic principles and operational control strategies of a DC inverter heat pump using a DC distribution network with the aim of contributing to the development and application of small DC distribution *** with the characteristics of a DC distribution network and different operating conditions,a DC inverter heat pump has the ability to adapt to changes in the DC bus voltage and adds flexibility to the *** models of the DC inverter heat pump integrated with an ice storage unit were *** control strategies of the DC inverter heat pump system considered the influence of both room temperature and varied bus voltage.A simulation study was conducted using MATLAB&Simulink software with simulation results validated by experimental *** results showed that:(1)The bus fluctuation under the rated working voltage had little effect on the operation of the unit;(2)When the bus voltage was fluctuating from 80%-90%or 105%-107%,the heat pump could still operate normally by reducing the frequency;(3)When the bus voltage was less than 80%or more than 107%,the unit needed to be shut down for the sake of equipment safety,so that the energy storage device could adjust to the sharp decrease or rise of voltage.

关键词： Photovoltaics energy storage direct current and flexibility DC inverter heat pump MATLAB&Simulink control strategy

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Mix-infections with different genotypes of HCV and with HCV plus other hepatitis viruses in patients with hepatitis C in China

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World Journal of Gastroenterology 2003年第5期9卷 984-992页

作者： Yuan-DingChen Ming-YingLiu Wen-linyu Jia-QiLi QinDai Zhen-QuanZhou SergioG.Tisminetzky KeyLaboratory InstituteofMedicalBiologyChineseAcademyofMedicalSciences&PekingUnionMedicalCollegeKunming650118YunnanProvinceChina KunmingHospitalforInfectiousDiseases Kunming650041YunnanProvinceChina Tisminetzky InternationalCentreforGeneticEngineeringandBiotechnologyTrieste34012Italy

AIM: Clinical therapy and prognosis in HCV infections are not good, and mix-infections with different HCV genotypes or quasispecies and mix-infections with HCV plus other hepatitis viruses are important concerns worldwide. The present report describes the sequence diversity and genotying of the 5'NCR of HCV isolates from hepatitis patients mix-infected with different HCV genotypes or variants, and the conditions of mix-infections with HCV plus other hepatitis viruses, providing important diagnostic and prognostic information for more effective treatment of HCV ***: The 5' non-coding region (5'NCR) of HCV was isolated from the patients sera and sequenced, and sequence variability and genotypes of HCV were defined by nucleotide sequence alignment and phylogenetic analysis, and the patients mix-infected with HCV plus other hepatitis viruses were analyzed. The conditions and clinical significance of mix-infections with HCV plus other hepatitis viruses were further ***: Twenty-four out of 43 patients with chronic hepatitis C were defined as mix-infected with different genotypes of HCV. Among these 24 patients, 9 were mixinfected with genotype 1 and 3, 7 with different variants of genotype 1, 2 with different variants of genotype 2, 6with different variants of genotype 3. No patients were found mix-infected with genotype 1 and 2 or with genotype 2 and 3. The clinical virological analysis of 60 patients mixinfected with HCV plus other hepatitis viruses showed that 45.0 % of the patients were mix-infected with HCV plus HAV, 61.7 % with HCV plus HBV, 6.7 % with HCV plus HDV/HBV, 8.4 % with HCV plus HEV, 3.3 % with HCV plus HGV. Infections with HCV plus other hepatitis viruses may exacerbate the pathological lesion of the ***: The findings in the present study imply that mix-infections with different HCV genotypes and mixinfections with HCV plus other hepatitis viruses were relatively high in Yunnan, China, providing important diagnosti

关键词：丙型肝炎病毒重叠感染丙型肝炎基因型中国流行病学

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Differences in endoscopic classification of early colorectal carcinoma between China and Japan: A comparative study

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World Journal of Gastroenterology 2003年第9期9卷 1985-1989页

作者： Ren-MinZhu Fang-YuWang IchiroHirata Ken-IchiKatsu Shu-DongXiao Zhong-linyu Zhi-HongZhang Zhao-MinXu DepartmentofGastroenterology.JinlingHospital Naming210002JiangsuProvincce.China TheSecondDepartmentof-IntemalMedicine OsakaMedicalCollegeTakatsuki569-8686.OsakaJapan ShanghaiInsti-tuteofDigestiveDiseases Shanghai200001China DepartmentofGastroenterology.CaoitalMedicalUniversity Beijing100050.China DepartmentofGastroenterology GulouHosiptalNanjing210008China

AIM: To compare the differences in the endoscopic classification of early colorectal carcinoma (CRC) betweenJapan and ***: Ten cases of early CRC were included in the study. After reviewing the color pictures of these cases, 5Japanese endoscopists and 5 Chinese endoscopists made their classificatory diagnosis individually using the current Japanese classification, and indicated their findings on which the diagnosis was ***: Some lesions diagnosed by the Japanese endoscopists as Ⅱa or Ⅱa plus Ⅱc, were classified as Is or Isp by the Chinese endoscopists. For superficial lesions consisting of elevation plus central depression, Ⅱa plus depression, Ⅱa plus Ⅱc or Ⅱc plus Ⅱa were classified according to the ratio of elevated area/depressed ***, international as well as interobserver difference still existed in the classification of such lesions. In addition,most Chinese endoscopists overlooked slightly depressed part on the top of a protruded lesion. Laterally spreading tumor, a special type of Ⅱa, was identified as LST by some Japanese ***: Discrepancies on macroscopic classification for early CRC do exist between Japanese and Chinese endoscopists, which are found not only in terminology but also in recognition of some lesions. In order to develop a universal classification, it needs for international communication and cooperation.

关键词：内窥镜结肠直肠癌中国日本对比分析

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Design of a new type of mine rescue relay cabin

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International Journal of Mining Science and Technology 2017年第4期27卷 711-715页

作者： Gao Na Chen Ruoyu Shen Jie Jin Longzhe Liu Jianguo Zhang Hao Wang Weixiang Fan linyu School of Civil and Resource Engineering University of Science and Technology Beijing Beijing 100083 China

This paper presents the design of an innovative mine emergency rescue relay cabin, and investigates a detailed comparison of existing shelter facilities, their function, service object, structures, size, and system components with the newly designed mine emergency rescue relay cabin. Air-tightness test indicated a test chamber relief rate of 26 Pa/min, which meets the design requirements. Furthermore,respirator replacement test showed an average time of 73.7 s to replace a respirator. The air cover air supply test indicated an air supply rate of 220 L/min, which is sufficient for the staff replacing the respirator in the emergency rescue relay cabin. The total air supply volume is 9680 L, which can be supplied via two compressed air cylinders of 40 L, pressurized to15 MPa.

关键词： Relay cabin site selection System and structure Air tightness Air cover air supply

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Energy scaling and extended tunability of a ring cavity terahertz parametric oscillator based on KTiOPO_(4) crystal

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Chinese Physics B 2018年第11期27卷 512-516页

作者： Yuye Wang Yuchen Ren Degang Xu Longhuang yang Yixin He Ci Song linyu Chen Changzhao Li Chao Yan Jianquan Yao Institute of Laser and Optoelectronics School of Precision Instruments and Optoelectronic EngineeringTianjin UniversityTianjin 300072China Key Laboratory of Optoelectronic Information Science and Technology(Ministry of Education) Tianjin UniversityTianjin 300072China College of Computer and Information Engineering Tianjin Agricultural UniversityTianjin 300384China

A wide terahertz tuning range from 0.96 THz to 7.01 THz has been demonstrated based on ring-cavity THz wave parametric oscillator with a KTiOPO_(4)(KTP)*** tuning range was observed intermittently from 0.96 THz to 1.87 THz,from 3.04 THz to 3.33 THz,from 4.17 THz to 4.48 THz,from 4.78 THz to 4.97 THz,from 5.125 THz to 5.168 THz,from5.44 THz to 5.97 THz,and from 6.74 THz to 7.01 *** dual-Stokes wavelengths resonance phenomena were observed in some certain tuning angle *** the theoretical analysis of the dispersion curve of the KTP crystal,the intermittent THz wave tuning range and dual-wavelength Stokes waves operation during angle tuning process were *** theoretical analysis was in good agreement with the experiment *** maximum THz output voltage detected by Golay cell was 1.7 V at 5.7 THz under the pump energy of 210 mJ,corresponding to the THz wave output energy of5.47μJ and conversion efficiency of 2.6×10^(-5).

关键词： terahertz parametric oscillator KTiOPO_(4)crystal extended tunability energy scaling

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Programmable deaminase-free base editors for G-to-Y conversion by engineered glycosylase

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National Science Review 2023年第8期10卷 78-87页

作者： Huawei Tong Nana Liu Yinghui Wei Yingsi Zhou Yun Li Danni Wu Ming Jin Shuna Cui Hengbin Li Guoling Li Jingxing Zhou Yuan Yuan Hainan Zhang linyu Shi Xuan Yao Hui yang HuidaGene Therapeutics Co. Ltd. Department of Neurology and Institute of Neurology of First Affiliated Hospital Institute of Neuroscience and Fujian Key Laboratory of Molecular Neurology Fujian Medical University Institute of Neuroscience Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of Sciences Shanghai Center for Brain Science and Brain-Inspired Intelligence

Current DNA base editors contain nuclease and DNA deaminase that enables deamination of cytosine(C)or adenine(A), but no method for guanine(G) or thymine(T) editing is available at present. Here we developed a deaminase-free glycosylase-based guanine base editor(gGBE) with G editing ability, by fusing Cas9 nickase with engineered N-methylpurine DNA glycosylase protein(MPG). By several rounds of MPG mutagenesis via unbiased and rational screening using an intron-split EGFP reporter, we demonstrated that gGBE with engineered MPG could increase G editing efficiency by more than 1500 ***, this gGBE exhibited high base editing efficiency(up to 81.2%) and high G-to-T or G-to-C(i.e. G-to-Y) conversion ratio(up to 0.95) in both cultured human cells and mouse embryos. Thus, we have provided a proof-of-concept of a new base editing approach by endowing the engineered DNA glycosylase the capability to selectively excise a new type of substrate.

关键词： glycosylase base excision repair base editor depurination deaminase-free transversion

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The“two-pronged”nanosystem to precisely improve lipid metabolism and inflammatory microenvironment for atherosclerotic plaque stabilization

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Nano Research 2023年第2期16卷 2706-2718页

作者： Huijuan Zhang linyu Gao Mingli Sui Jingjing Wang Yaping Wang Xiangyang Xuan Zhenzhong Zhang Ling Zhu Lin Hou School of Pharmaceutical Sciences Zhengzhou UniversityZhengzhou 450001China Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases Zhengzhou 450001China Collaborative Innovation Center of New Drug Research and Safety Evaluation Zhengzhou 450001China

The rupture of atherosclerosis(AS)vulnerable plaque is the major cause of fatal arterial thrombosis related *** lipid dysbolism and pro-inflammatory microenvironment are considered two main driving factors for plaque ***,a“two-pronged”nanosystem LCS-Se/Res was designed to efficiently stabilize AS plaques,by precisely regulating lipid metabolism and inflammatory ***-Se/Res was constructed with the core of resveratrol(Res)loaded selenium(Se)nanoparticles(NPs),and the shell(LCS)of targeting peptide(LSIPPKA)modified chitosan(CS).This system was stable in blood *** it arrived at the plaque site,LCS-Se/Res could actively recognize the highly expressed lectin-like oxidized low-density lipoprotein receptor 1(LOX-1)receptor and accumulate ***,Res was released from LCS-Se nanocarriers in situ by responding to acidic plaque *** the one hand,Res increased autophagy flux in damaged endothelial cells by activating cAMP-PKA-AMPK-SIRT1 signaling pathway to promote lipid ***,LCS-Se also promoted cholesterol efflux to improve lipid *** the other hand,fixed-point separated Res and LCS-Se synergistically improved plaque inflammatory microenvironment by reversing macrophage phenotype(M1 to M2)and alleviating plaque oxidative *** result proved that the plaque vulnerability index(VI)decreased from 1.39±0.282 to 0.108±0.02 after LCS-Se/Res *** short,this study provided a new therapeutic strategy for the atherosclerosis through the two-pronged approach.

关键词： atherosclerotic plaque stabilization autophagy lipid metabolism inflammatory infiltration selenium nanoparticles resveratrol

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基于福建50年滑坡灾情数据的滑坡时序特征分析

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山西建筑 2025年第2期51卷 93-96,103页

作者：王琳彧邓钟肖陈偲石璇林圆欣闽江学院地理与海洋学院福建福州350108 自然资源部东南生态脆弱区监测修复工程技术创新中心福建福州350108

福建省山地多,年降雨量较丰富,降雨引起滑坡灾害多发。收集了福建省1969年—2018年近50年的已发滑坡灾情数据,提取已发滑坡时间和空间位置信息,建立时间序列模型,分析福建省近50年已发滑坡的时间特征。结果表明:采样福建省已发灾害数据... 详细信息

福建省山地多,年降雨量较丰富,降雨引起滑坡灾害多发。收集了福建省1969年—2018年近50年的已发滑坡灾情数据,提取已发滑坡时间和空间位置信息,建立时间序列模型,分析福建省近50年已发滑坡的时间特征。结果表明:采样福建省已发灾害数据模拟构建的ARIMA(1,2,1)时间序列模型,以4年为一个周期,可以有效地预测福建省崩塌滑坡年度发生的频次,经实际检验误差在±10次之内。

关键词：滑坡灾情数据时序特征数据序列

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