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Multi-Objective Optimization Algorithm for Grouping Decision Variables Based on Extreme Point Pareto Frontier

Computers, Materials & Continua 2024年第4期79卷 1281-1299页

作者： JunWang linxi zhang Hao zhang Funan Peng Mohammed A.El-Meligy Mohamed Sharaf Qiang Fu College of Computer Science and Technology Shenyang University of Chemical TechnologyShenyang110142China Key Laboratory of Intelligent Technology for Chemical Process Industry of Liaoning Province Shenyang University of Chemical TechnologyShenyang110142China Industrial Engineering Department College of EngineeringKing Saud UniversityP.O.Box 800Riyadh11421Saudi Arabia

The existing algorithms for solving multi-objective optimization problems fall into three main categories:Decomposition-based,dominance-based,and *** multi-objective optimization problemsmainly focus on objectives,treating decision variables as a total variable to solve the problem without consideringthe critical role of decision variables in objective *** seen,a variety of decision variable groupingalgorithms have been ***,these algorithms are relatively broad for the changes of most decisionvariables in the evolution process and are time-consuming in the process of finding the Pareto *** solvethese problems,a multi-objective optimization algorithm for grouping decision variables based on extreme pointPareto frontier(MOEA-DV/EPF)is *** algorithm adopts a preprocessing rule to solve the Paretooptimal solution set of extreme points generated by simultaneous evolution in various target directions,obtainsthe basic Pareto front surface to determine the convergence effect,and analyzes the convergence and distributioneffects of decision *** the later stages of algorithm optimization,different mutation strategies are adoptedaccording to the nature of the decision variables to speed up the rate of evolution to obtain excellent individuals,thusenhancing the performance of the *** validation of the test functions shows that this algorithmcan solve the multi-objective optimization problem more efficiently.

关键词： Multi-objective evolutionary optimization algorithm decision variables grouping extreme point pareto frontier

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《流民图》里里寄忠情:廉吏郑侠的别样人生

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文史知识 2024年第8期 41-47页

作者：陈玺张琳嬉西北政法大学法治学院

纵观中国历史,没有哪一个朝代像宋代这样蕴含着尖锐的矛盾和普遍的冲突。陈寅恪先生在《邓广铭宋史职官志考证序》中指出:“华夏民族之文化,历数千载之演进,造极于赵宋之世。”在娘变与危机并存的时代背景下,诞生了十一世纪中国最为重... 详细信息

纵观中国历史,没有哪一个朝代像宋代这样蕴含着尖锐的矛盾和普遍的冲突。陈寅恪先生在《邓广铭宋史职官志考证序》中指出:“华夏民族之文化,历数千载之演进,造极于赵宋之世。”在娘变与危机并存的时代背景下,诞生了十一世纪中国最为重要的系统性社会变革——熙宁变法。熙宁变法作为这一时期关键性时间节点,围绕着“新法”与“更化”的政治斗争从未停息。在整个熙宁变法的改革过程中,曾因郑侠进献《流民图》抨击新法,改变了此次改革的历史走向,并成为熙宁年间诸多政策调整和人事变动之关节所在。

关键词：熙宁变法人事变动职官志邓广铭郑侠《流民图》陈寅恪先生时间节点

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文本类型理论视角下的中成药说明书英译探究——以加味逍遥丸为例

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科教文汇 2024年第12期 185-188页

作者：陕茜张林熹湖北中医药大学外国语学院湖北武汉430065

随着全球化发展和“一带一路”建设的推进,中医药也在逐步走向世界。准确恰当地英译中成药说明书,使国外消费者了解药品功效,有助于海外中药市场的开拓和中医药文化的传播。在文本类型理论的视角下,以加味逍遥丸的说明书为例,从药名、... 详细信息

随着全球化发展和“一带一路”建设的推进,中医药也在逐步走向世界。准确恰当地英译中成药说明书,使国外消费者了解药品功效,有助于海外中药市场的开拓和中医药文化的传播。在文本类型理论的视角下,以加味逍遥丸的说明书为例,从药名、主治功能、注意事项的英译,探索更适合中成药说明书英译的理论和方法。即英译时,既需要关注说明书中信息的准确性,又应以目的语读者期待的方式产生感召效果,促进药品消费,推动中医药产品销售。

关键词：文本类型理论中成药说明书中医英译

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Metal-organic-framework-derived copper-based catalyst for multicomponent C-S coupling reaction

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Chinese Journal of Chemical Engineering 2024年第6期70卷 1-8页

作者： Lixin Chen Hui zhang linxi Hou Xin Ge Key Laboratory of Synthetic and Biological Colloids Ministry of EducationSchool of Chemical and Material EngineeringJiangnan UniversityWuxi 214122China Department of Materials-Oriented Chemical Engineering School of Chemical EngineeringFuzhou UniversityFuzhou 350116China Qingyuan Innovation Laboratory Quanzhou 362801China

Copper-based metal-organic frameworks(Cu-MOFs)are a promising multiphase catalyst for catalyzing C-S coupling reactions by virtue of their diverse structures and ***,the unpleasant odor and instability of the organosulfur,as well as the mass-transfer resistance that exists in multiphase catalysis,have often limited the catalytic application of Cu-MOFs in C-S coupling *** this paper,a Cu-MOFs catalyst modified by cetyltrimethylammonium bromide(CTAB)was designed to enhance mass transfer by increasing the adsorption of organic substrates using the long alkanes of ***,elemental sulfur was used to replace organosulfur to achieve a highly efficient and atom-economical multicomponent C-S coupling reaction.

关键词： Design Copper-based metal-organic frameworks (Cu-MOFs) Adsorption C-S coupling reaction Multiphase reaction

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饲料学课程思政教学探索

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畜牧兽医杂志 2024年第1期43卷 71-73页

作者：东丽丽孙伟武江小帆杨礼马君军张林溪甘肃农业大学应用技术学院甘肃临洮730050

课程思政是我国目前高等教育改革的新举措,习近平总书记强调,以课堂教学为主渠道,将各类课程与思政课程有机融合,使专业知识和立德树人并肩同行。《饲料学》作为动物科学专业的核心课程,在培养专业技术人才方面有着不可替代的作用。本... 详细信息

课程思政是我国目前高等教育改革的新举措,习近平总书记强调,以课堂教学为主渠道,将各类课程与思政课程有机融合,使专业知识和立德树人并肩同行。《饲料学》作为动物科学专业的核心课程,在培养专业技术人才方面有着不可替代的作用。本文在探索《饲料学》课程特色和优势的基础上,加强对课程所蕴藏思想政治元素和价值观的探索和提炼,并在本课程的设计、讲授、考核和评价等各个环节中嵌入课程思政元素,将专业知识的传授和价值观的培育有机结合,以期在有效提高《饲料学》课程教学效果的同时激发学生的爱国情怀和民族自豪感,引导学生以科学的态度去探索真理,并为同专业其他课程的改革提供参考。

关键词：饲料学课程思政教学探索

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High-precision RCS measurement of aircraft's weak scattering source

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Chinese Journal of Aeronautics 2016年第3期29卷 772-778页

作者： Hu Chufeng Li Nanjing Chen Weijun zhang linxi Science and Technology on UAV Laboratory Northwestern Polytechnical University

The radar cross section （RCS） of weak scattering source on the surface of an aircraft is usually less than -40 dBsm. How to accurately measure the RCS characteristics of weak scattering source is a technical challenge for the aircraft＇s RCS measurement. This paper proposes separating and extracting the two-dimensional （2D） reflectivity distribution of the weak scattering source with the microwave imaging algorithm and spectral transform so as to enhance its measurement preci- sion. Firstly, we performed the 2D microwave imaging of the target and then used the 2D gating function to separate and extract the reflectivity distribution of the weak scattering source. Secondly, we carried out the spectral transform of the reflectivity distribution and eventually obtained the RCS of the weak scattering source through calibration. The prototype experimental results and their analysis show that the measurement method is effective. The experiments on an aircraft＇s low-scattering conformal antenna verify that the measurement method can eliminate the clutter on the surface of aircraft. The precision of measuring a -40 dBsm target is 3 5 dB better than the existing RCS measurement methods. The measurement method can more accurately obtain the weak scattering source＇s RCS characteristics.

关键词： Microwave imaging RCS measurement Reftectivity distributionSpectral transform Weak scattering source

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Ordered quasi-two-dimensional structure of nanoparticles in semiflexible ring polymer brushes under compression

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Frontiers of physics 2017年第3期12卷 149-156页

作者： Yunfeng Hua Zhenyu Deng Yangwei Jiang linxi zhang Department of Physics Zhejiang_University Hangzhou 310027 China

Molecular dynamics simulations of a coarse-grained bead-spring model of ring polymer brushes un- der compression are presented. Flexible polymer brushes are always disordered during compression, whereas semiflexible polymer brushes tend to be ordered under sufficiently strong compression. Fur- ther, the polymer monomer density of the semiflexible polymer brush is very high near the brush surface, inducing a peak value of the free energy near the surface. Therefore~ when nanoparticles are compressed in semifiexible ring polymer brushes, they tend to exhibit a closely packed single-layer structure between the brush surface and the impenetrable wall, and a quasi-two-dimensional ordered structure near the brush surface is formed under strong compression. These findings provide a new approach to designing responsive applications.

关键词： molecular dynamics simulation semiflexible ring polymer brushes nanoparticle,compression ordered structure

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Repurposing diacerein to suppress colorectal cancer growth by inhibiting the DCLK1/STAT3 signaling pathway

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Chinese Journal of Natural Medicines 2024年第4期22卷 318-328页

作者： YE Qiaobei ZHU Yu SHI Meng LV linxi GONG Yuyan zhang Luyao YANG Lehe ZHAO Haiyang ZHAO Chengguang XU Huanhai Affiliated Yueqing Hospital Wenzhou Medical UniversityWenzhou 325600China The Institute of Life Sciences Biomedical Collaborative Innovation Center of Zhejiang ProvinceWenzhou UniversityWenzhou 325035China School of Pharmaceutical Sciences Wenzhou Medical UniversityWenzhou 325035China

Double cortin-like kinase 1(DCLK1)exhibits high expression levels across various cancers,notably in human colorectal cancer(CRC).Diacerein,a clinically approved interleukin(IL)-1βinhibitor for osteoarthritis treatment,was evaluated for its impact on CRC proliferation and migration,alongside its underlying mechanisms,through both in vitro and in vivo *** study employed MTT assay,colony formation,wound healing,transwell assays,flow cytometry,and Hoechst 33342 staining to assess cell proliferation,migration,and ***,proteome microarray assay and western blotting analyses were conducted to elucidate diacerein’s specific mechanism of *** findings indicate that diacerein significantly inhibits DCLK1-dependent CRC growth in vitro and in *** high-throughput proteomics microarray and molecular docking studies,we identified that diacerein directly interacts with ***,the suppression of p-STAT3 expression following DCLK1 inhibition by diacerein or specific DCLK1 siRNA was ***,diacerein effectively disrupted the DCLK1/STAT3 signaling pathway and its downstream targets,including MCL-1,VEGF,and survivin,thereby inhibiting CRC progression in a mouse model,thereby inhibiting CRC progression in a mouse model.

关键词： DCLK1 Diacerein Rhein STAT3 Colorectal cancer

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Average fidelity estimation of twirled noisy quantum channel using unitary 2t-design

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Chinese Physics B 2019年第1期28卷 223-231页

作者：张林曦朱畅华裴昌幸 State Key Laboratory of Integrated Services Networks Xidian UniversityXi’an 710071China Science and Technology on Communication Networks Laboratory Shijiazhuang 050081China

We propose a method to estimate the average fidelity using the unitary 2t-design of a twirled noisy channel, which is suitable for large-scale quantum circuits. Compared with the unitary 2-design in randomized benchmarking, the unitary2t-design for the twirling of noisy channels is more flexible in construction and can provide more information. In addition,we prove that the proposed method provides an efficient and reliable estimation of the average fidelity in benchmarking multistage quantum gates and estimating the weakly gate-and time-dependent noise. For time-dependent noise, we provide a scheme of moment superoperator to analyze the noise in different experiments. In particular, we give a lower bound on the average fidelity of a channel with imperfect implementation of benchmarking and state preparation and measurement errors(SPAM).

关键词： quantum channel average fidelity unitary 2t-design

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3'-Sialyllactose regulates glucose and lipid metabolic disorders via the gut–liver axis in mice fed a high-fat die

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Food Science and Human Wellness 2024年

作者： Wei zhang Meizhen Zhu Kelsang Dekyi linxi Zheng Yichen zhang Youping Lv Dongbei Guo Xiaoxuan Chen Lili Pan Xinyue Wang Hongwei Li State Key Laboratory of Vaccines for Infectious Diseases Xiang An Biomedicine Laboratory School of Public Health Xiamen University State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics National Innovation Platform for Industry-Education Integration in Vaccine Research Xiamen University Department of Nutrition Zhongshan Hospital (Xiamen) Fudan University Xiamen Clinical Research Center for Cancer Therapy

Recent research has indicated that sialic acid， such as free sialic acid (N-acetylneuraminic acid， Neu5Ac) and bound sialic acid (3'-sialyllactose， 3'-SL)， can ameliorate disorders associated with glycolipid metabolism， although the underlying mechanisms have yet to be determined. We examined the effects of 3'-SL on glycolipid metabolism in mice fed a high-fat diet. Male C57BL/6J mice were divided into six groups: two model control groups (normal and high-fat diets) and four intervention groups [Neu5Ac， and low-，moderate-， and high-dose 3'-SL]. After 8 weeks of continuous gavage intervention， mice in the 3'-SL intervention groups had lower body weight and total fat content; reduced fasting blood glucose， triglycerides， low-density lipoproteins and oxidized-low-density lipoproteins; and increased high-density lipoproteins，but no dosage-dependent of 3'-SL intervention was found， 3’-SL＿M intervention as optimal for further exploration. 3'-SL intervention could increase respiratory exchange ratio， energy expenditure， and amount of exercise performed. 3'-SL increased the colonic abundances of Akkermansia， Lactobacillus， and Bacteroides， and reduced those of Erysipelatoclostridium， Faecalibaculum， and Aldercreutzia. Changes were also observed in colonic metabolites， and liver gene transcript and metabolites， which were mainly enriched in bile secretion， taurine and hypotaurine metabolism， and insulin resistance. Additionally， 3'-SL was observed to regulate genes associated with physiological rhythms， including clock， per2， cry1， and bhihe41. Collectively， our findings indicate that 3'-SL can contribute to the prevention and control of disorders associated with glucose and lipid metabolism caused by high-fat diets. Compared with Neu5Ac， 3'-SL intervention can ameliorate intestinal flora disorders， enhance bile acid circulation， increase tissue energy expenditure， and reduce lipid synthesis， thereby promoting lipid-lowering effects mediated via the liver–gut axis， and can a

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