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新工科背景下地方高校“专创双培”实践教学体系建设的研究——以内蒙古民族大学为例

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呼伦贝尔学院学报 2024年第3期32卷 137-141页

作者：赵琳娜王海珍内蒙古民族大学内蒙古通辽028043

快速发展的产业变革亟需高校培养创新型工程人才与之对接。本文以内蒙古民族大学为例,针对地方高校创新人才培养过程中存在的建设资源不足、专业培养与创新培养脱节、校企合作助力不足等问题,提出了深化校企合作,构建“专创双培”实践... 详细信息

快速发展的产业变革亟需高校培养创新型工程人才与之对接。本文以内蒙古民族大学为例,针对地方高校创新人才培养过程中存在的建设资源不足、专业培养与创新培养脱节、校企合作助力不足等问题,提出了深化校企合作,构建“专创双培”实践教学体系,建立“线下+线上”创新创业实践建设模式,从实践教学和实践资源建设两方面提升创新创业人才培养质量,为提高地方院校创新型工程人才培养提供了参考思路。

关键词：新工科地方高校创新能力实践教学专创双培

BMA probability quantitative precipitation forecasting of land-falling typhoons in south-east China

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Frontiers of Earth Science 2019年第4期13卷 758-777页

作者： linna zhao Xuemei BAI Dan QI Cheng XING Chinese Academy of Meteorological Sciences Beijing 100081China Heilongjiang Meteorological Observatory Harbin 150001China National Meteorological Centre Beijing 100081China Heilongjiang Mulan County Meteorological Observatory Mulan 151900China

The probability of quantitative precipitation forecast(PQPF)of three Bayesian Model Averaging(BMA)models based on three raw super ensemble prediction schemes(i.e.,A,B,and C)are established,which through calibration of their parameters using 1-3 day precipitation ensemble prediction systems(EPSs)from the China Meteorological Administration(CMA),the European Centre for Medium-Range Weather Forecasts(ECMWF)and the National Centers for Environmental Prediction(NCEP)and observation during land-falling of three typhoons in south-east China in *** comparison of PQPF shows that the performance is better in the BMA than that in raw ensemble *** average,the mean absolute error(MAE)of 1 day lead time forecast is reduced by 12.4%,and its continuous ranked probability score(CRPS)of 1-3 day lead time forecast is reduced by 26.2%,*** the amount of precipitation prediction by the BMA tends to be underestimated,but in view of the perspective of probability prediction,the probability of covering the observed precipitation by the effective forecast ranges of the BMA are increased,which is of great significance for the early warning of torrential rain and secondary disasters induced by it.

关键词： Bayesian model averaging probabilistic quantitative precipitation forecasting ensemble prediction typhoon precipitation

The foxtail millet Si69 gene is a Wali7 (wheat aluminum-induced protein 7) homologue and may function in aluminum tolerance

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Chinese Science Bulletin 2009年第10期54卷 1697-1706页

作者： zhao linna zhao Qian AO GuangMing YU JingJuan State Key Laboratory for Agro-Biotechnology College of Biological Sciences China Agricultural University Beijing 100193 China

We isolated a clone, named Si69, from a foxtail millet immature seed cDNA library. The protein encoded by Si69 contains a conserved Wali7 (wheat aluminum induced protein 7) domain and shares high-level homology with aluminum-induced proteins from other species including rice and Arabidopsis. The Si69 gene presents as a single locus in foxtail millet genome and is globally expressed in all tissues examined. Its expression is up-regulated by aluminum. The sequence feature and expression pattern suggest that the Si69 gene is involved in aluminum tolerance or detoxification. To confirm its biological functions, Si69 controlled by the CaMV35S promoter was introduced into Arabidopsis. Transgenic plants did not show any visible morphological changes compared to wild-type plants under normal growth conditions. However, when treated with 20 or 50 μmol/L Aluminum (Al), the root apices of wild-type plants were heavily stained by hematoxylin, whereas those of Si69 transgenic plants were not stained when treated with 20 μmol/L Al and slightly stained when treated with 50 μmol/L Al. Scanning electron microscopy (SEM) results further demonstrated that the damage of the root apices was se- verer in wild-type plants than in transgenic plants. Inhibition of root growth and accumulation of malondialdehyde (MDA), an indicator of lipid peroxidation, were lower in transgenic plants than in wild-type plants. The results show that overexpression of Si69 may increase Al tolerance in transgenic plants, indicating that a series of Wali7-containing genes may play similar roles in Al tolerance/detoxification.

关键词： Si69 诱导蛋白耐铝性基因组同源性谷子小麦转基因植物

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银屑病合并代谢综合征的机制

中国皮肤性病学杂志 2024年第4期38卷 466-472页

作者：丁海宁赵琳娜朱琪宋静娜张琴王红梅天津中医药大学研究生院天津301617 天津中医药大学第一附属医院国家中医针灸临床医学研究中心天津300381 天津市中医药研究院附属医院皮肤科天津300120

银屑病(psoriasis)是一种免疫介导的慢性复发性炎症性皮肤病,临床上常伴发多种并发症,加大了治疗的难度和风险。近年来多项研究证实,银屑病与代谢综合征的临床指征密切相关,银屑病患者是代谢综合征的高风险人群,代谢综合征又增加了银屑... 详细信息

银屑病(psoriasis)是一种免疫介导的慢性复发性炎症性皮肤病,临床上常伴发多种并发症,加大了治疗的难度和风险。近年来多项研究证实,银屑病与代谢综合征的临床指征密切相关,银屑病患者是代谢综合征的高风险人群,代谢综合征又增加了银屑病的复发几率和严重程度。银屑病合并代谢综合征的发病机制涉及遗传学、胰岛素抵抗、氧化应激、内质网应激、炎性因子、脂肪因子、肠道菌群等多种因素,这些因素导致银屑病合并代谢综合征的治疗需区别于常规治疗方案,否则将加剧疾病的发展。本文对银屑病合并代谢综合征的机制进行总结,旨在为相关临床研究和动物实验提供参考。

关键词：银屑病代谢综合征银屑病合并代谢综合征机制

Separation of cortical arteries and veins in optical neurovascular imaging

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Journal of Innovative Optical Health Sciences 2014年第3期7卷 22-30页

作者： linna zhao Yao Li Hongyang Lu Lu Yuan Shanbao Tong Med-X Research Institute Shanghai Jiao Tong University1954 Huashan Rd.Shanghai 200030P.R.China School of Biomedical Engineering Shanghai Jiao Tong University800 Dongchuan Rd. Shanghai 200240P.R.China School of Life Science and TechnologyHuazhong University of Science and Technology 1037 Luoyu Rd. Wuhan 430074P.R.China

Separation of arteries and veins in the cerebral cortex is of significant importance in the studies of cortical hemodynamics,such as the changes of cerebral blood flow,perfusion or oxygen con-centration in arteries and veins under different pathological and physiological *** the cerebral vessel segmentation and vessel-type separation are challenging due to the complexity of cortical vessel characteristics and low spatial signal-to-noise *** this work,we presented an effective full-field method to differentiate arteries and veins in cerebral cortex using dual-modal optical imaging technology including laser speckle imaging(LSI)and optical intrinsic signals(OIS)*** raw contrast images were acquired by LSI and processed with enhanced laser speckle contrast analysis(eLASCA),*** vascular pattern was extracted and seg-mented using region growing algorithm from the eLASCA-based ***,OIS imageswere acquired altermatively with 630 and 870 nm to obtain an oxy hemoglobin concentration mapover cerebral *** the separation of arteries and veins was accomplished by Otsuthreshold segmentation algorithm based on the OIS information and segmentation of ***,the segmentation and separation performances were assessed using area overlap measure(AOM).The segmentation and separation of cerebral vessels in cortical optical imaging have great potential applications in full-field cerebral hemodynamics monitoring and pathological study of cerebral vascular diseases,as well as in clinical intraoperative monitoring.

关键词： Vessel segmentation laser speckle imaging optical intrinsic signals imaging regiongrowing algorithm artery-vein separation.

Precipitation data and their uncertainty as input for rainfallinduced shallow landslide models

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Frontiers of Earth Science 2019年第4期13卷 695-704页

作者： Yueli CHEN linna zhao Ying WANG Qingu JIANG Dan QI State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China China Institute of Water Resources and Hydropower Research Beijing 100038China National Meteorological Center Beijing 100081China

Physical models used toforecast the temporal occurrence of rainfall-induced shallow landslides are based on deterministic *** to the existing measuring technology and our knowledge of the physical laws controlling landslide initiation,model uncertainties are due to an inability to accurately quantify the model input parameters and rainfall forcing *** uncertainty analysis of slope instability prediction provides a rationale for refining the geotechnical *** Transient Rainfall Infiltration and Grid-based Regional Slope Stability-Probabilistic(TRIGRS-P)model adopts a probabilistic approach to compute the changes in the Factor of Safety(FS)due to rainfall *** Infiltration Distributed Equilibrium(SLIDE)is a simplified physical model for landslide *** new code(SLIDE-P)is also modified by adopting the same probabilistic approach to allow values of the SLIDE model input parameters to be sampled *** study examines the relative importance of rainfall variability and the uncertainty in the other variables that determine slope *** precipitation data from weather stations,China Meteorological Administration Land Assimilation System 2.0(CLDAS2.0),China Meteorological Forcing Data set precipitation(CMFD),and China geological hazard bulletin are used to drive TRIGRS,SLIDE,TRIGRS-P and SLIDE-P *** TRIGRS-P and SLIDE-P models are used to generate the input samples and to calculate the values of *** outputs of several model runs with varied input parameters and rainfall forcings are analyzed statistically.A comparison suggests that there are significant differences in the simulations of the TRIGRS-P and SLIDE-P *** different precipitation data sets are used,the simulation results of TRIGRS-P are more *** study can inform the potential use of numerical models toforecast the spatial and temporal occurrence of regional rainfall-induced shallow landslides.

关键词： rainfall-induced landslide SLIDE TRIGRS FS

Degradation and breakdown behaviors of SGTs under repetitive unclamped inductive switching avalanche stress

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Chinese Physics B 2022年第9期31卷 482-487页

作者： Chenkai Zhu linna zhao Zhuo Yang Xiaofeng Gu Engineering Research Center ofIoT Technology Applications(Ministry of Education) Department of Electronic EngineeringJiangnan UniversityWuxi 214122China Wuxi NCE Power Company Ltd.Wuxi 214028China

The repetitive unclamped inductive switching(UIS)avalanche stress is conducted to investigate the degradation and breakdown behaviors of conventional shield gate trench MOSFET(C-SGT)and P-ring SGT MOSFETs(P-SGT).It is found that the static and dynamic parameters of both devices show different degrees of *** experimental and simulation results,the hot holes trapped into the Si/SiO_(2) interface and the increase of crystal lattice temperature should be responsible for the degradation and breakdown ***,under repetitive UIS avalanche stress,the reliability of P-SGT overcomes that of C-SGT,benefitting from the decreasing of the impact ionization rate at bottom of field oxide caused by the existence of P-ring.

关键词： shield gate trench MOSFET repetitive unclamped inductive switching stress degradation static and dynamic parameters

甘露醇氯化钠琼脂培养基成分对鉴定金黄色葡萄球菌的影响

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中国食品卫生杂志 2024年第4期36卷 369-376页

作者：马嘉琦李艳艳刘小燕白继超刘峰崔生辉赵琳娜杨保伟西北农林科技大学食品科学与工程学院陕西杨凌712100 北京奥博星生物科技有限公司北京100193 中国食品药品检定研究院北京100050

目的探究甘露醇氯化钠琼脂培养基成分中氯化钠和胰酪胨对甘露醇氯化钠琼脂培养基质量的影响,同时考察市售5个国产品牌和1个进口品牌的甘露醇氯化钠琼脂培养基的产品质量。方法采用不同品牌不同浓度的氯化钠和胰酪胨配制成甘露醇氯化... 详细信息

目的探究甘露醇氯化钠琼脂培养基成分中氯化钠和胰酪胨对甘露醇氯化钠琼脂培养基质量的影响,同时考察市售5个国产品牌和1个进口品牌的甘露醇氯化钠琼脂培养基的产品质量。方法采用不同品牌不同浓度的氯化钠和胰酪胨配制成甘露醇氯化钠琼脂培养基,应用平板涂布计数、半定量划线法探究氯化钠和胰酪胨对甘露醇氯化钠琼脂培养基质量的影响;对不同种金黄色葡萄球菌和大肠杆菌在5个国产品牌和1个进口品牌的甘露醇氯化钠琼脂培养基上的生长情况进行定量测定。参照GB 4789.28-2013比较不同品牌培养基对不同菌株的生长率、生长指数和菌落大小的影响,对培养基质量进行评价。结果实验菌株在使用不同种类、不同浓度的氯化钠或胰酪胨配制的甘露醇氯化钠琼脂培养基上的生长率、生长指数存在较大差异;不同品牌的甘露醇氯化钠琼脂培养基非目标菌生长指数均合格,但目标菌的生长率和菌落生长大小存在显著差异。结论氯化钠和胰酪胨对于甘露醇氯化钠琼脂培养基质量影响较大,会直接决定培养基的质量是否合格,市售的国内外不同品牌甘露醇氯化钠琼脂培养基质量存在较大差异,国产甘露醇氯化钠琼脂培养基的质量优于进口培养基。

关键词：金黄色葡萄球菌大肠杆菌甘露醇氯化钠培养基氯化钠胰酪胨质量控制

Adaptive Optimal Output Regulation of Interconnected Singularly Perturbed Systems With Application to Power Systems

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IEEE/CAA Journal of Automatica Sinica 2024年第3期11卷 595-607页

作者： Jianguo zhao Chunyu Yang Weinan Gao linna Zhou Xiaomin Liu the Engineering Research Center of Intelligent Control for Underground Space Ministry of EducationChina University of Mining and TechnologyXuzhou 221116 the School of Information and Control Engineering China University of Mining and TechnologyXuzhou 221116 IEEE the State Key Laboratory of Synthetical Automation for Process Industries Northeastern UniversityShenyang 110819China

This article studies the adaptive optimal output regulation problem for a class of interconnected singularly perturbed systems(SPSs) with unknown dynamics based on reinforcement learning(RL).Taking into account the slow and fast characteristics among system states,the interconnected SPS is decomposed into the slow time-scale dynamics and the fast timescale dynamics through singular perturbation *** the fast time-scale dynamics with interconnections,we devise a decentralized optimal control strategy by selecting appropriate weight matrices in the cost *** the slow time-scale dynamics with unknown system parameters,an off-policy RL algorithm with convergence guarantee is given to learn the optimal control strategy in terms of measurement *** combining the slow and fast controllers,we establish the composite decentralized adaptive optimal output regulator,and rigorously analyze the stability and optimality of the closed-loop *** proposed decomposition design not only bypasses the numerical stiffness but also alleviates the *** efficacy of the proposed methodology is validated by a load-frequency control application of a two-area power system.

关键词： Adaptive optimal control decentralized control output regulation reinforcement learning(RL) singularly perturbed systems(SPSs)