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四季草莓新品种京滇红的选育

果树学报 2022年第5期39卷 902-904页

作者：董静钟传飞王桂霞常琳琳隗永青孙健孙瑞张宏力高用顺万红许利平陈杉艳张运涛北京市农林科学院林业果树研究所·北京市草莓工程技术研究中心·农业农村部华北地区园艺作物生物学与种质创制重点实验室北京100093 云南省农业科学院园艺作物研究所昆明650205 承德市农林科学院河北承德067060 昆明市农业科学研究院昆明650221

京滇红是由四季草莓Charlotte实生种子选出的四季草莓新品种。果实圆锥形,纵横径比1.02,果个中等,大小比较整齐,果面较平整,种子稀,平于果面。果实红色、有光泽,果肉橙黄,髓心橙黄,空洞中等大小,有特殊香味,酸多甜少。夏季平均单果质量1... 详细信息

京滇红是由四季草莓Charlotte实生种子选出的四季草莓新品种。果实圆锥形,纵横径比1.02,果个中等,大小比较整齐,果面较平整,种子稀,平于果面。果实红色、有光泽,果肉橙黄,髓心橙黄,空洞中等大小,有特殊香味,酸多甜少。夏季平均单果质量15.0 g,果实可溶性固形物含量(w,后同)8.3%,硬度0.40 kg·cm^(-2)。京滇红抗性强,具有四季开花结果特性,夏季连续结果能力强。采用春栽方式时,6月份进入采收期,有保温条件的可持续到12月份。适合在云南等夏季冷凉地区冷棚避雨栽培。

关键词：四季草莓新品种京滇红

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瞬时受体电位通道与心肌肥大研究进展

生命的化学 2021年第3期41卷 558-564页

作者：连婷谈远佳徐盼袁伟朱美萍常林林张世忠三峡大学医学院宜昌443002

瞬时受体电位(transient receptor potential,TRP)通道家族是一类广泛分布于人体各组织和器官的阳离子通道。近年来研究发现,部分表达于心肌细胞的TRP通道亚家族成员在病理性心肌肥大中发挥重要作用,目前关于TRP通道与心肌肥大研究的大... 详细信息

瞬时受体电位(transient receptor potential,TRP)通道家族是一类广泛分布于人体各组织和器官的阳离子通道。近年来研究发现,部分表达于心肌细胞的TRP通道亚家族成员在病理性心肌肥大中发挥重要作用,目前关于TRP通道与心肌肥大研究的大量实验结果提示,TRP通道有可能成为干预病理性心肌肥大的重要靶点,TRP通道在病理性心肌肥大中的作用和机制成为一个研究热点。本文主要对参与病理性心肌肥大的TRP通道及其可能机制的最新进展进行综述。

关键词： TRP通道心肌细胞心肌肥大药理靶点

Carbon dots modified nanoflower petals with super enhanced nitrogen electro-reduction efficiency

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Chinese Chemical Letters 2023年第6期34卷 406-411页

作者： Yang Zhou Xuanzhao Lu Yu-chung chang Yanwen Ma linlin Wang Jianrong Zhang Junjie Zhu State Key Laboratory for Organic Electronics and Information Displays&Institute of Advanced Materials IAM Nanjing University of Posts&TelecommunicationsNanjing 210023China State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China School of Mechanical and Materials Engineering Washington State UniversityPullmanWA 99164United States

Nitrogen electro-reduction reaction(NERR)is a promising alternative method for ammonia production to the Haber-Bosch approach due to mild reaction conditions and free harmful by-product emission.A formidable challenge in bringing NERR closer to the practical application is developing an electrocatalyst which can simultaneously improve the Faraday efficiency and reduce the reaction ***,we fabricated a catalyst of nitrogen-doped carbon dots modified copper-phosphate nanoflower petals(Cu Po-NCDs NF)via a self-assembly *** flower structure endowed the Cu Po-NCDs NF with large specific surface area,and thus enabled more active sites to be *** particular,we demonstrated that the NCDs modified Cu Po petals with flower-like structure can accelerate the interfacial proton-electron transfer,suppressing the competing hydrogen evolution reaction and promoting the desired NERR ***,for the CuPo-NCDs NF catalyzed NERR,the FE_(NH_(3))and the reaction potential both were boosted,the resultant energy efficiency of NERR reached a record-breaking value of 56.5%,and the NH_(3)yield rate increased by 7 times compared to *** study provides a novel catalyst with a new pathway to boost the NERR.

关键词： Nitrogen-doped carbon dots Nano-flower Self-assembly Interfacial proton-electron transfer Nitrogen electro-reduction

Aligned Ion Conduction Pathway of Polyrotaxane‑Based Electrolyte with Dispersed Hydrophobic Chains for Solid‑State Lithium–Oxygen Batteries

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Nano-Micro Letters 2025年第2期17卷 169-186页

作者： Bitgaram Kim Myeong‑chang Sung Gwang‑Hee Lee Byoungjoon Hwang Sojung Seo Ji‑Hun Seo Dong‑Wan Kim Department of Materials Science and Engineering Korea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea School of Civil Environmental and Architectural EngineeringKorea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea Materials Science and Chemical Engineering Center Institute for Advanced Engineering(IAE)Yongin 17180Republic of Korea

A critical challenge hindering the practical application of lithium–oxygen batteries(LOBs)is the inevitable problems associated with liquid electrolytes,such as evaporation and safety *** study addresses these problems by proposing a modified polyrotaxane(mPR)-based solid polymer electrolyte(SPE)design that simultaneously mitigates solvent-related problems and improves ***-SPE exhibits high ion conductivity(2.8×10^(−3)S cm^(−1)at 25℃)through aligned ion conduction pathways and provides electrode protection ability through hydrophobic chain *** this mPR-SPE into solid-state LOBs resulted in stable potentials over 300 *** situ Raman spectroscopy reveals the presence of an LiO_(2)intermediate alongside Li_(2)O_(2)during oxygen *** situ X-ray diffraction confirm the ability of the SPE to hinder the permeation of oxygen and moisture,as demonstrated by the air permeability *** present study suggests that maintaining a low residual solvent while achieving high ionic conductivity is crucial for restricting the sub-reactions of solid-state LOBs.

关键词： Solid polymer electrolyte Lithium-oxygen batteries Polyrotaxane ion conductivity Hydrophobic chain

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan Zhao Yidan Zhang Xin Liu Jian Zhang Ya Gao Shuyue Li Cui chang Xiang Liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

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玫瑰豆乳冰淇淋的研制

现代食品 2018年第5期3卷 141-144页

作者：徐珊袁志浩窦玉萍常琳琳张松林马姝雯西北民族大学生命科学与工程学院甘肃兰州730124

利用豆乳为主料,配以玫瑰制成具有特殊玫瑰风味且具有保健功能的冰淇淋,并对影响冰淇淋感官及膨胀率的因素进行了探索,通过正交试验确定出玫瑰豆乳冰淇淋的最佳配方。结果表明:以豆乳65%、玫瑰浸提物6%、脂肪2%、甜味剂12%(砂糖∶果葡糖... 详细信息

利用豆乳为主料,配以玫瑰制成具有特殊玫瑰风味且具有保健功能的冰淇淋,并对影响冰淇淋感官及膨胀率的因素进行了探索,通过正交试验确定出玫瑰豆乳冰淇淋的最佳配方。结果表明:以豆乳65%、玫瑰浸提物6%、脂肪2%、甜味剂12%(砂糖∶果葡糖浆=2∶1)、复配乳化稳定剂4%(为CMC-Na∶蛋黄粉∶单甘酯=1:1:1)制作出的冰淇淋色泽自然,是一种风味独特且具保健性的冰淇淋。豆乳中含有大量蛋白质等多种营养物质,以豆乳代替牛乳加以其他辅料制作冰淇淋不仅可以满足人们的正常营养需求还可以增加风味减少脂肪摄入,符合我国人民健康低脂的要求。

关键词：玫瑰豆乳低脂

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草莓果实香气形成及调控机制研究进展

中国蔬菜 2024年第6期 24-30页

作者：赵凤佳王桂霞孙健常琳琳钟传飞李双桃董静隗永青张宏力张运涛吴瑞刚孙瑞河北工程大学园林与生态工程学院河北邯郸056038 北京市农林科学院林业果树研究所北京100093 北京市草莓工程技术研究中心北京100093

草莓是一种受欢迎的高经济价值水果,其独特的果香与其所含的挥发性有机化合物(VOCs)密切相关。果实香气品质对评估草莓食用价值和商品价值起到了至关重要的作用,成为近年草莓产业领域的研究热点。本文综述了草莓果实香气物质的组分,影... 详细信息

草莓是一种受欢迎的高经济价值水果,其独特的果香与其所含的挥发性有机化合物(VOCs)密切相关。果实香气品质对评估草莓食用价值和商品价值起到了至关重要的作用,成为近年草莓产业领域的研究热点。本文综述了草莓果实香气物质的组分,影响果实香气的因素(品种、果实成熟度、栽培方式),贮藏、加工过程中香气物质的变化以及草莓香气形成的分子调控机制等方面的研究进展,以期为草莓香气育种提供参考。

关键词：草莓香气物质影响因素分子调控

High‑Entropy Electrode Materials:Synthesis,Properties and Outlook

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Nano-Micro Letters 2025年第1期17卷 472-506页

作者： Dongxiao Li chang Liu Shusheng Tao Jieming Cai Biao Zhong Jie Li Wentao Deng Hongshuai Hou Guoqiang Zou Xiaobo Ji College of Chemistry and Chemical Engineering Central South UniversityChangsha 410083People’s Republic of China School of Chemistry and Chemical Engineering Hunan Institute of EngineeringXiangtan 411104People’s Republic of China

High-entropy materials represent a new category of high-performance materials,first proposed in 2004 and extensively investigated by researchers over the past two *** definition of high-entropy materials has continuously *** the last ten years,the discovery of an increasing number of high-entropy materials has led to significant advancements in their utilization in energy storage,electrocatalysis,and related domains,accompanied by a rise in techniques for fabricating high-entropy electrode ***,the research emphasis has shifted from solely improving the performance of high-entropy materials toward exploring their reaction mechanisms and adopting cleaner preparation ***,the current definition of high-entropy materials remains relatively vague,and the preparation method of high-entropy materials is based on the preparation method of single metal/low-or medium-entropy *** should be noted that not all methods applicable to single metal/low-or medium-entropy materials can be directly applied to high-entropy *** this review,the definition and development of high-entropy materials are briefly ***,the classification of high-entropy electrode materials is presented,followed by a discussion of their applications in energy storage and catalysis from the perspective of synthesis ***,an evaluation of the advantages and disadvantages of various synthesis methods in the production process of different high-entropy materials is provided,along with a proposal for potential future development directions for high-entropy materials.

关键词： High-entropy Energy storage Electrode materials

Deciphering the molecular mechanisms of Simiaowan in the treatment of hyperuricemia: in vivo and in silico approaches

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Traditional Medicine Research 2025年第2期10卷 37-54页

作者： Yong-chang Zeng Jun-Hong Wu Dan-Dan Xu Kang He chang-Qing Liu Li-Fei Song Zheng-Zhi Wu Qian-Qian Jiang Shao-Yu Liang Department of Neurology The First Affiliated Hospital of Shenzhen UniversityShenzhen 518020China Pharmaceutical Department The Affiliated TCM Hospital of Guangzhou Medical UniversityGuangzhou 510000China School of Pharmacy Guizhou University of Traditional Chinese MedicineGuiyang 550025China Guangzhou Zeli Medical Technology Co. Ltd.Guangzhou 510700China

Background:Simiaowan(SMW),a well-known traditional Chinese medicine,has been employed to treat hyperuricemia(HUA)and gout for ***,the bioactive components and underlying mechanisms have not been *** objective of this study was to identify the active components and potential mechanisms of SMW by integrating pharmacological experimentation,serum pharmacochemistry,network pharmacology and molecular ***:HUA rats modelling by high-fat/high-sugar diet and potassium oxonate/adenine oral administration were used to evaluate the pharmacodynamic effects of ***-Q-Exactive-MS/MS was employed to detect the bioactive components present in SMW-containing *** pharmacology and molecular docking were utilized to elucidate the potential targets and underlying ***:SMW effectively ameliorated HUA rats via the inhibition of uric acid(UA)production,promotion of UA excretion,improvement of lipid and glucose metabolic abnormalities,antioxidant,anti-inflammatory and anti-insulin resistance effects.A total of 73 compounds detected in SMW-containing serum were identified as potential active components,with alkaloids,flavonoids,organic acids,and terpenoids emerging as the primary active *** 203 corresponding targets were obtained as SMW anti-HUA/gout targets,which mainly participated in apoptosis,insulin resistance,TNF,PI3K-Akt,HIF-1,NF-κB,MAPK,IL-17 and TLR signaling *** docking indicated that active compounds(***,phellodendrine,quercetin,formononetin,ferulic acid)had superior binding abilities to the key targets(*** carrier family 22 member 12(URAT1),solute carrier family 22 member 6(OAT1),ATP-binding cassette sub-family G member 2(ABCG2),solute carrier family 2,facilitated glucose transporter member 9(GLUT9),xanthine dehydrogenase/oxidase(XDH),transcription factor p65(RELA),toll-like receptor 4(TLR4),prostaglandin G/H synthase 2(PTGS2),caspase-3(CASP3),insulin(INS)).Conclusion:S

关键词： hyperuricemia network pharmacology serum pharmacochemistry Simiaowan UPLC-Q-Exactive-MS/MS