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Advances in Atmospheric Sciences 2023年第12期40卷 2169-2182页

作者： Wei TAO linlin zheng Ying HAO Gaoping LIU Anhui Meteorology Observatory Hefei 230031China

Arctic changes influence not only temperature and precipitation in the midlatitudes but also contribute to severe *** study investigates an extreme gale event that occurred on 30 April 2021 in East China and was forced by an Arctic potential vorticity(PV)anomaly *** advection steered by storms contributed to the equatorward propagation of Arctic high PV,forming the Northeast China cold vortex(NCCV).At the upper levels,a PV southward intrusion guided the combination of the polar jet and the subtropical jet,providing strong vertical wind shear and downward momentum transportation to the *** PV anomaly cooled the upper troposphere and the northern part of East China,whereas the lower levels over southern East China were dominated by local warm air,thus establishing strong instability and *** addition,the entrainment of Arctic dry air strengthened the surface pressure gradient by evaporation *** the above mechanism has the potential to improve convective weather forecasts under climate *** study suggests that the more frequent NCCV-induced gale events in recent years are partly due to high-latitude waviness and storm activities,and this hypothesis needs to be investigated using more cases.

关键词： PV anomaly Arctic storm Northeast China cold vortex convection extreme gale

Can Ecological Product Win Consumers in China？ A Study on the Effect of Product Attributes and Consumers＇ Face Consciousness on Ecological Product Preference

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Frontiers of Business Research in China 2014年第2期8卷 182-205页

作者： Zhuomin Shi linlin Wen Wanyi zheng School of Business Sun Yat-Sen University Guangzhou 510275 China

This research explores what product attributes consumers value and how consumer face consciousness influences ecological product preference. Study I shows that environmental attribute enhances product preference to a greater extent when consumers value gentleness-related attributes more than strength-related attributes. However, when the strength-related attributes are valued, the benefit of environmental attribute is attenuated, and sometimes even leads to greater preference for non-ecological products. Study lI reveals that Chinese consumers with high face consciousness show a significant difference between explicit and implicit preferences for ecological products. In other words, these consumers believe in only their own preference for ecological products. In contrast, Chinese consumers with low face consciousness show no difference between explicit and implicit preferences, i.e., they believe that other people prefer ecological products as much as they do.

关键词： ecological product product attributes face consciousness product preference

Improvement of plasma uniformity and mechanical properties of Cr ﬁlms deposited on the inner surface of a tube by an auxiliary anode near the tube tail

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Plasma Science and Technology 2022年第5期24卷 64-74页

作者： Houpu WU Xiubo TIAN linlin zheng Chunzhi GONG Peng LUO State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin150001People’s Republic of China

In order to improve the length of plasma in a whole tube and mechanical properties of Cr films deposited on the inner surface of the tube, a high-power impulse magnetron sputtering coating method with a planar cathode target and auxiliary anode was proposed. The auxiliary anode was placed near the tube tail to attract plasma into the inner part of the tube. Cr films were deposited on the inner wall of a 20# carbon steel tube with a diameter of 40 mm and length of 120 mm. The influence of auxiliary anode voltage on the discharge characteristics of the Cr target, and the structure and mechanical properties of Cr films deposited on the inner surface of the tube were explored. With higher auxiliary anode voltage, an increase in substrate current was observed, especially in the tube tail. The thickness uniformity, compactness, hardness and H/E ratios of the Cr films deposited on the inner surface of the tube increased with the increase in auxiliary anode voltage. The Cr films deposited with auxiliary anode voltage of 60 V exhibited the highest hardness of 9.6 GPa and the lowest friction coefficient of 0.68.

关键词： high-power impulse magnetron sputtering auxiliary anode inner surface Cr films

Polymorphism in the Hsa-miR-4274 seed region influences the expression of PEX5 and enhances radiotherapy resistance in colorectal cancer

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Frontiers of Medicine 2024年第5期18卷 921-937页

作者： Qixuan Lu Ningxin Ren Hongxia Chen Shaosen Zhang Ruoqing Yan Mengjie Li linlin zheng Wen Tan Dongxin Lin State Key Laboratory of Molecular Oncology Department of Etiology and CarcinogenesisBeijing Key Laboratory for Carcinogenesis and Cancer PreventionNational Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaGuangzhou 510060China

Identifying biomarkers for predicting radiotherapy efficacy is crucial for optimizing personalized *** previously reported that rs1553867776 in the miR-4274 seed region can predict survival in patients with rectal cancer receiving postoperative chemoradiation ***,to investigate the molecular mechanism of the genetic variation and its impact on the radiosensitivity of colorectal cancer(CRC),in this study,bioinformatics analysis is combined with functional experiments to confirm peroxisomal biogenesis factor 5(PEX5)as a direct target of *** miR-4274 rs1553867776 variant influences the binding of miR-4274 and PEX5 mRNA,which subsequently regulates PEX5 protein *** interaction between PEX5 and Ku70 was verified by co-immunoprecipitation and immunofluorescence.A xenograft tumor model was established to validate the effects of miR-4274 and PEX5 on CRC progression and radiosensitivity in *** overexpression of PEX5 enhances radiosensitivity by preventing Ku70 from entering the nucleus and reducing the repair of ionizing radiation(IR)-induced DNA damage by the Ku70/Ku80 complex in the *** addition,the enhanced expression of PEX5 is associated with increased IR-induced ***,targeting this mechanism might effectively increase the radiosensitivity of *** findings offer novel insights into the mechanism of cancer radioresistance and have important implications for clinical radiotherapy.

关键词： colorectal cancer polymorphism miR-4274 PEX5 radiotherapy resistance

Confinement fluorescence effect of an aggregation-induced emission luminogen in crystalline polymer

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Aggregate

Aggregate 2023年第5期4卷 112-119页

作者： Lan Zhou linlin zheng Xiaoxiao Yu Mengyue Gao Chengjian Xu Yifan Ge Tianxiang Bai Jin Wen Yanhua Cheng Meifang Zhu State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringDonghua UniversityShanghaiChina

Despite the impressive progress of stimuli-responsive fluorescent materials,little is known about the influence of confinement created by crystalline polymer over the fluorescence properties of fluorescent *** effects of confinement on the fluorescence of an aggregation-induced emission luminogen(AIEgen)are investigated using computational simulations,which reveal that the confined space induces the AIEgens to take a more planar conformation,resulting in a red-shifted emission *** this property,the study is extended to explore the confinement generated by various polymer crystalline forms,and it is shown that different fluorescence colors are *** confinement fluorescence effect is attributed to the different spatial dimensions of the polymer amorphous layer between lamellar crystals where the AIEgens are *** results indicate the immediate association between crystalline structure and fluorescence signals,activating unprecedented photophysical properties of luminescent materials,and also providing the possibility for crystalline structure visualization,it is important for the many polymer crystallization processes occurring in the materials processing.

关键词： aggregation-induced emission confinement fluorescence effect polymer crystalline structure

Interface construction of NiCo LDH/NiCoS based on the 2D ultrathin nanosheet towards oxygen evolution reaction

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Nano Research 2022年第6期15卷 4986-4995页

作者： Jiahui Li Lili Wang Haojia He Yiquan Chen Zirui Gao Na Ma Bing Wang linlin zheng Rulin Li Yujia Wei Junqing Xu Yao Xu Bowen Cheng Zhen Yin Ding Ma State Key Laboratory of Separation Membranes and Membrane Processes School of ChemistryTiangong UniversityTianjin 300387China School of Chemical Engineering and Technology Tiangong UniversityTianjin 300387China Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular Engineering and College of Engineeringand BIC-ESATPeking UniversityBeijing 100871China College of Chemical Engineering and Materials Science Tianjin University of Science and TechnologyTianjin 300457China China Tianchen Engineering Corporation Tianjin 300400China

Carbon-free hydrogen as a promising clean energy source can be produced with electrocatalysts via water *** evolution reaction(OER)as anodic reaction determines the overall efficiency of water electrolysis due to sluggish OER ***,it’s much desirable to explore the efficient and earth-abundant transition-metal-based OER electrocatalysts with high current density and superior stability for industrial alkaline ***,we demonstrate a significant enhancement of OER kinetics with the hybrid electrocatalyst arrays in alkaline via judiciously combining earth-abundant and ultrathin NiCo-based layered double hydroxide(NiCo LDH)nanosheets with nickel cobalt sulfides(NiCoS)with a facile metal-organic framework(MOF)-template-involved surface sulfidation *** obtained NiCo LDH/NiCoS hybrid arrays exhibits an extremely low OER overpotential of 308 mV at 100 mA·cm^(−2),378 mV at 200 mA·cm^(−2)and 472 mV at 400 mA·cm^(−2)in 1 M KOH solution,respectively.A much low Tafel slope of 48 mV·dec^(−1)can be ***,with the current density from 50 to 250 mA·cm^(−2),the NiCo-LDH/NiCoS hybrid arrays can run for 25 h without any *** results demonstrate that the construction of hybrid arrays with abundant interfaces of NiCo LDH/NiCoS can facilitate OER kinetics via possible modulation of binding energy of O-containing intermediates in alkaline *** present work would pave the way for the development of lowcost and efficient OER catalysts and industrial application of water alkaline electrolyzers.

关键词： oxygen evolution reaction hybrid structure ultrathin nanosheet layered double hydroxide surface sulfidation interface of NiCo LDH/NiCoS

Construction of 3D hollow NiCo-layered double hydroxide nanostructures for high-performance industrial overall seawater electrolysis

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Nano Research 2024年第11期17卷 9472-9482页

作者： Lili Wang Di Wang linlin zheng Xiaorong Song Ya Yan Jiahui Li Shuheng Tian Maolin Wang Mi Peng Zhaohui Yin Hong Wang Junqing Xu Bowen Cheng Zhen Yin Ding Ma State Key Laboratory of Separation Membranes and Membrane Processes School of Chemistry Tiangong University Tianjin 300387 China Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular Engineering and College of Engineering and BIC-ESAT Peking University Beijing 100871 China College of Chemical Engineering and Materials Science Tianjin University of Science and Technology Tianjin 300457 China State Key Laboratory of Biobased Fiber Manufacturing Technology Tianjin University of Science and Technology Tianjin 300457 China School of Materials Science and Engineering Tiangong University Tianjin 300387 China China Tianchen Engineering Corporation Tianjin 300400 China

Green hydrogen production via seawater electrolysis holds a great promise for carbon-neutral energy production. However, the development of efficient and low-cost bifunctional electrocatalysts for seawater electrolysis at an industrial level remains a significant challenge. Herein, we report a facile approach based on one-dimensional (1D) cobalt carbonate hydroxide (CCH) nanoneedles (NNs) as skeleton and zeolitic imidazolate framework-67 (ZIF-67) as a sacrificial template to construct a self-supported NiCo layered double hydroxide (NiCo LDH) heterostructure nanocage (CCH@NiCo LDH) anchoring on the carbon felt (CF). The NiCo LDHs have hollow features, consisting of ultrathin layered hydroxide nanosheets. Benefiting from the structural advantages, unique carbon substrate and desirable composition, three-dimensional (3D) NiCo LDH nanocages exhibit superior performance as a bifunctional catalyst for overall seawater splitting at an industrial level and good corrosion resistance in alkaline media. In the alkaline seawater (1 M KOH + 0.5 M NaCl), it exhibits low overpotentials of 356 mV for hydrogen evolution reaction (HER) and 433 mV for oxygen evolution reaction (OER) at 400 mA·cm^(−2), much better than most of reported non-noble metal catalysts. Consequently, the obtained CF electrode loading of CCH@NiCo LDH exhibits outstanding performance as anodes and cathodes for overall alkaline seawater splitting, with remarkably low cell voltages of 1.56 and 1.89 V at current densities of 10 and 400 mA·cm^(−2), respectively. Moreover, the robust stability of 100 h is also demonstrated at above 200 mA·cm^(−2) in alkaline seawater. Our present work demonstrates significant potential for constructing effective cost-efficient and non-noble-metal bifunctional electrocatalyst and electrode for industrial seawater splitting.

关键词： seawater splitting bifunctional electrocatalyst NiCo layered double hydroxide(NiCo LDH) hollow nanocages carbon felt

Effects of augmenting the migratory ability of mouse BMDC on immunotherapy

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Journal of Nanjing Medical University 2006年第3期20卷 133-140页

作者： Xun Zhu linlin Zhen Wei zheng Xuanyi Wang zhengyan Wu Department of General Surgery First Affiliated Hospital of Nanjing Medical University Nanjing 210029 China

Objective： Being antigen-presenting cells, dendritic cells （DCs） transport captured antigen from peripheral tissues to T cell zone of lymph nodes via lymphatic vessels. This migration is essential for the presentation of antigen that leads to priming of effector T cell responses. In this study, we tried to promote the migratory ability of mouse bone marrow-derived dendritic cells （BMDCs） loaded with antigen of breast cancer, and its immunological effect in vivo. Methods： After being loaded with breast carcinoma antigen, BMDCs were cultured with medium containing PGE2, LTC4, or Bryo-1 respectively. Phenotypic changes, CCR7 expression, chemotaxis assay, mixed lymphocyte response, specific T lymphocyte cytotoxicity assay and anti-tumor immune efficacy of BMDCs were observed. Results ： PGF2 and LTC4 promoted maturation, CCR7 expression and migratory ability of BMDCs compared with control group in vitro. In vivo PGE2 and LTC4 group vaccines were more efficient on suppressing growth of mouse breast cancer than other groups. However Bryo-1 only enhanced BMDCs maturation. Conclusion： Because the effect of specific CTL in vitro had no difference, we suggested that migration of dendritic cells to lymph nodes maybe answered for the better anti-tumor immunological response induced by PGE2 or LTC4 in vivo.

关键词： dendritic cells breast carcinoma chemokines immunological therapy

原始性创新人格形成的影响因素实证研究——基于BP神经网络训练与DEMATEL测算的方法

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科技进步与对策 2016年第18期33卷 140-145页

作者：郑琳琳福州大学经济与管理学院福建福州350116

在阅读大量国内外文献的基础上,对原始性创新人格影响因素进行了总结和补充,通过建立和训练BP神经网络确定了影响因素综合权值,结合DEMATEL算法,对1901-2012年诺贝尔物理学奖获得者原始性创新人格形成影响因素进行了重要性分析。按照中... 详细信息

在阅读大量国内外文献的基础上,对原始性创新人格影响因素进行了总结和补充,通过建立和训练BP神经网络确定了影响因素综合权值,结合DEMATEL算法,对1901-2012年诺贝尔物理学奖获得者原始性创新人格形成影响因素进行了重要性分析。按照中心度计算结果,对原始性创新人格形成影响因素进行了排序,根据原因度结果,判定哪些属于原因类影响因素,探寻诺贝尔物理学奖获得者原始性创新人格形成规律。最后,提出了有益于塑造原始性创新人格的对策。

关键词： BP神经网络 DEMATEL算法原始性创新原始性创新人格影响因素

三大技术创新主体科技成果与经济增长关系研究——基于国家创新体系与VAR模型的实证分析

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科技进步与对策 2016年第2期33卷 32-39页

作者：郑琳琳福州大学经济与管理学院福建福州350108

在探讨技术创新主体构成、主体不同研究性质及对应经济效益的基础上,对产学研合作背景下的三大技术创新主体与经济增长关系进行了梳理。基于中国1986-2011年的时间序列数据,采用VAR模型,综合运用格兰杰因果检验、脉冲响应函数和方差分解... 详细信息

在探讨技术创新主体构成、主体不同研究性质及对应经济效益的基础上,对产学研合作背景下的三大技术创新主体与经济增长关系进行了梳理。基于中国1986-2011年的时间序列数据,采用VAR模型,综合运用格兰杰因果检验、脉冲响应函数和方差分解,对中国不同技术创新主体的科技成果与经济增长进行了动态分析。研究表明,企业科技成果对经济发展成效较好,其次是高校,而科研机构科技成果对经济增长的促进作用比企业和高校小得多。结合中国不同技术创新主体的科技成果产出效应进行实证分析,为不同技术创新主体协同实现科技成果对经济增长的正向影响提出了对策建议。

关键词：国家创新体系技术创新主体科技成果经济增长