检索结果-南通市图书馆

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

锰氧化物在水系电池中的研究进展与挑战

硅酸盐学报 2024年第1期52卷 273-291页

作者：杜玲玉毕嵩山牛志强烟台大学环境与材料工程学院山东烟台264005 南开大学化学学院天津300071

水系二次电池因其安全性高、成本低以及对环境友好等特点,在大规模储能领域展现出广阔的应用前景。电极材料作为电池的关键组成部分,其性质直接影响电池电化学性能。锰氧化物具有晶体结构丰富、理论比容量高、氧化还原电位高、成本低等... 详细信息

水系二次电池因其安全性高、成本低以及对环境友好等特点,在大规模储能领域展现出广阔的应用前景。电极材料作为电池的关键组成部分,其性质直接影响电池电化学性能。锰氧化物具有晶体结构丰富、理论比容量高、氧化还原电位高、成本低等优势,被认为是最具发展潜力的正极材料之一。然而,锰氧化物存在导电性差、结构不稳定、锰溶解等问题,使电池面临倍率和循环性能差的严峻挑战,限制了其实际应用。此外,锰氧化物的反应机制较为复杂。针对上述问题,本文通过调研有关锰氧化物的文献,首先分析了其晶体结构类型和特点,进一步按照电解液酸度梳理归纳了锰氧化物在(弱)酸性和碱性条件下的反应机制,简要阐述了其在水系碱金属离子、多价金属离子以及非金属离子二次电池体系的研究进展,最后对未来高性能锰氧化物正极的发展方向进行了展望。

关键词：水系电池锰氧化物晶体结构反应机制

流体剪切力调控血脑屏障的力学生物学机制研究

在线全文

学校读者我要写书评

暂无评论

四川大学学报（医学版） 2024年第1期55卷 74-80页

作者：杜聆语许博闻程琳岳红燕张怀奕沈阳四川大学华西基础医学与法医学院生物医学工程研究室成都610041

目的血脑屏障(blood-brain barrier,BBB)主要由脑微血管内皮细胞组成。本研究以大鼠脑微血管内皮细胞(rat brain microvascular endothelial cells,rBMECs)为模式细胞,探索正常生理、缺血低灌注和术后高灌注条件下的流体剪切力(flow she... 详细信息

目的血脑屏障(blood-brain barrier,BBB)主要由脑微血管内皮细胞组成。本研究以大鼠脑微血管内皮细胞(rat brain microvascular endothelial cells,rBMECs)为模式细胞,探索正常生理、缺血低灌注和术后高灌注条件下的流体剪切力(flow shear force,FSF)对BBB结构功能的保护、损伤和破坏的力学生物学机制。方法以1×10^(5)细胞/cm^(2)的密度接种rBMECs培养48 h,对rBMECs分别施加0.5、2和20 dyn/cm2的FSF,模拟脑血管狭窄的低灌注、正常生理和搭桥术后高剪切力作用下BBB结构的受力情况;同时设置静态培养组rBMECs作为对照(不施加力)。光学显微镜、扫描电子显微镜(SEM)以及激光共聚焦显微镜(LSCM)观察细胞形态和骨架的变化。透射电子显微镜(TEM)观察细胞紧密连接,免疫荧光染色检测紧密连接相关蛋白(claudin-5、occludin、ZO-1)、黏着连接相关蛋白(VE-cadherin、PECAM-1)分布的变化。Western blot检测不同强度FSF下紧密连接相关蛋白(claudin-5、ZO-1、JAM4),黏着连接相关蛋白(VE-cadherin)和Rho GTPases信号关键蛋白(Rac1、Cdc42、RhoA)的表达。结果镜下观察发现:静态培养和低剪切作用(0.5 dyn/cm2)下细胞骨架排列紊乱,取向无规律;正常生理剪切作用(2 dyn/cm^(2))下,细胞骨架顺应FSF方向重排,胞间观察到有效的紧密连接结构;高剪切作用(20 dyn/cm^(2))下,细胞间间隙增大,未观察到有效的紧密连接结构。免疫荧光染色发现低剪切作用时,细胞间距减小,但胞间连接处紧密连接相关蛋白和黏着连接相关蛋白分布较少;正常生理条件下细胞连接紧密,大部分紧密连接相关蛋白的分布集中在胞间连接处;高剪切作用时,胞间距离显著增大,连接紧密和黏着连接的结构被破坏。Western blot结果发现:低剪切作用下,claudin-5、ZO-1和VE-cadherin与对照组相比均上调(P<0.05);正常生理剪切作用下,claudin-5、ZO-1、JAM4以及VE-cadherin与对照组相比均呈现高表达(P<0.05);高剪切作用下,claudin-5、ZO-1、JAM4以及VEcadherin的表达与正常生理剪切作用组比较下调(P<0.05);生理条件下胞内的Rho GTPases(Rac1、Cdc42、RhoA)表达上调,高于其他实验组(P<0.05),而低剪切和高剪切作用下的Rho GTPases表达均较正常生理剪切作用组下调(P<0.05)。结论正常生理条件下的FSF有助于维持BBB结构的完整性,而低剪切或高剪切均会损伤或破坏血脑屏障的结构,FSF对BBB的调控与紧密连接相关蛋白和黏着连接相关蛋白的表达和分布密切相关。

关键词：血脑屏障流体剪切力大鼠脑微血管内皮细胞紧密连接相关蛋白黏着连接相关蛋白

Algebraic encoding scheme for aperture 3 hexagonal discrete global grid system

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2018年第2期61卷 215-227页

作者： BEN Jin LI YaLu ZHOU ChengHu WANG Rui du lingyu Institute of Surveying and Mapping Information Engineering University State Key Laboratory of Resources and Environmental Information System Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of Sciences College of Earth Science and Surveying Engineering China University of Mining and Technology (Beijing)

Discrete Global Grid Systems(DGGSs) are spatial references that use a hierarchical tessellation of cells to partition and address the entire globe. They provide an organizational structure that permits fast integration between multiple sources of large and variable geospatial data sufficient for visualization and analysis. Despite a significant body of research supporting hexagonal DGGSs as the superior choice, the application thereof has been hindered owing in part to the lack of a rational hierarchy with an efficient addressing system. This paper presents an algebraic model of encoding scheme for the Aperture 3 Hexagonal(A3H) DGGS. Firstly, the definition of a grid cell, which is composed of vertices, edges, and a center, is introduced to describe fundamental elements of grids. Secondly, by identifying the grid cell with its center, this paper proves that cell centers at different levels can be represented exactly using a mixed positional number system in the complex plane through the recursive geometric relationship between two successive levels, which reveals that grid cells are essentially special complex radix numbers. Thirdly, it is shown that through the recursive geometric relationship of successive odd or even levels, the mixed positional number system can also be applied to uniquely represent cell centers at different levels under specific constraint conditions, according to which the encoding scheme is designed. Finally, it is shown that by extending the scheme to 20 triangular faces of the regular icosahedron,multi-resolution grids on closed surfaces of the icosahedron are addressed perfectly. Contrast experiments show that the proposed encoding scheme has the advantages of theoretical rigor and high programming efficiency and that the efficiency of cross-face adjacent cell searching is 242.9 times that of a similar scheme. Moreover, the proposed complex radix number representation is an ideal formalized description tool for grid systems. The research i

关键词： Discrete Global Grid System Hexagon Positional number system Algebraic encoding

A novel method of determining the optimal polyhedral orientation for discrete global grid systems applicable to regionalscale areas of interest

在线全文

学校读者我要写书评

暂无评论

International Journal of Digital Earth 2020年第12期13卷 1553-1569页

作者： Jianbin Zhou Jin Ben Rui Wang Mingyang Zheng Xiaochuang Yao lingyu du PLA Strategic Support Force Information Engineering University ZhengzhouPeople’s Republic of China College of Land Science and Technology China Agricultural UniversityBeijingPeople’s Republic of China Troops of 31617 FuzhouPeople’s Republic of China

The polyhedral discrete global grid system(DGGS)is a multi-resolution discrete earth reference model supporting the fusion and processing of multi-source geospatial *** orientation of the polyhedron relative to the earth is one of its key design choices,used when constructing the grid system,as the efficiency of indexing will decrease if local areas of interest extend over multiple faces of the spherical *** date,most research has focused on global-scale applications while almost no rigorous mathematical models have been established for determining orientation *** this paper,we propose a method for determining the optimal polyhedral orientation of DGGSs for areas of interest on a regional *** proposed method avoids splitting local or regional target areas across multiple polyhedral *** the same time,it effectively handles geospatial data at a global scale because of the inherent characteristics of *** show that the orientation determined by this method successfully guarantees that target areas are located at the center of a single polyhedral *** orientation process determined by this novel method reduces distortions and is more adaptable to different geographical areas,scales,and base polyhedrons than those employed by existing procedures.

关键词： Discrete global grid systems single polyhedral face convex polygons rotate and translate cost function

A universal spray printing strategy to prepare gradient hybrid architectures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Carbon Energy 2022年第4期4卷 517-526页

作者： lingyu du Songshan Bi Yang Hu Rui Wang Jiacai Zhu Minghui Zhang Zhiqiang Niu Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Renewable Energy Conversion and Storage CenterCollege of ChemistryNankai UniversityTianjinP.R.China

Functionally gradient materials(FGMs)have attracted tremendous attention due to their unique properties and ***,it is still a great challenge to prepare scalable FGMs by a universal,cost-effective,and highly efficient ***,a strategy of combining in situ concentration regulation and spraying is developed to fabricate continuously gradient composite films(GCFs),where the component gradient variation can be well *** strategy is universal and versatile,which is beneficial to inducing different components into GCFs with gradient distributions and further constructing them with diverse configurations on various *** gradient design endows the composite films with excellent mechanical strength and gradient electron transport pathways,which ensures that GCFs directly serve as the electrodes in electrochemical *** a proof of concept,free-standing GCFs based on V2O5 nanomaterials are used as cathodes of aqueous zinc-ion *** resultant devices deliver superior electrochemical performances in comparison with the counterparts of homogeneous ***,this universal strategy provides a promising route in the scalable production of FGMs and further extends their applications in various fields.

关键词： aqueous zinc-ion batteries functionally gradient materials spraying universality

Structural basis of interaction between the hepatitis C virus p7 channel and its blocker hexamethylene amiloride

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Protein & Cell 2016年第4期7卷 300-304页

作者： Linlin Zhao Shuqing Wang lingyu du Jyoti Dev Liujuan Zhou Zhijun Liu James J. Chou Bo OuYang National Center for Protein Science State Key Laboratory of Molecular Biology Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of Sciences Shanghai 200031 China Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics) School of Pharmacy Tianjin Medical University Tianjin 300070 China Department of Biological Chemistry and Molecular Pharmacology Harvard Medical School Boston MA 02115 USA Shanghai Science Research Center Chinese Academy of Sciences. Shanahai 201204. China

Dear Editor, Hepatitis C virus （HCV） infection, which causes hepatitis C and can chronically lead to serious and life-threatening dis- eases including liver cirrhosis and hepatocellular carcinoma （Lauer and Walker, 2001）, is a rising global health problem. More than 170 million people are infected by HCV worldwide and 3-4 million people are infected each year. No effective vaccines are available to prevent HCV infection. Moreover, HCV is a fast mutating RNA virus with seven distinct genotypes and many subtypes within each genotype. The high degree of genetic diversity can lead to further viral resistance to the current therapies within individual patients （Li et al., 2012）. Hence, there remains a strong desire in the medical community to explore new therapeutic opportunities.

关键词： Hexamethylene Rimantadine Chemical Shift Perturbation Nuclear Overhauser Enhancement Channel Cavity

Depositional Responses to the Mongol-Okhotsk Ocean Closure in the Central Area of the Great Xing’an Range: Insights into Thrust Faults and Foreland Basins

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2024年第3期35卷 797-811页

作者： Zheren Zhao Shichao Li lingyu Zhang College of Earth Sciences Jilin UniversityChangchun 130061China Key Laboratory of Mineral Resources Evaluation in Northeast Asia Ministry of Natural ResourcesChangchun 130061China Department of Geosciences and Natural Resource Management University of CopenhagenCopenhagen 1350Denmark

The Mongol-Okhotsk Ocean,which has been closing gradually from the west to the east beginning since the Late Paleozoic,was an important part of the Central Asian Orogenic *** influenced the tectonic framework of Northeast Asia in the Mesozoic,especially the Late Mesozoic arc-basin system that is widely distributed in the Great Xing’an ***,the manner in which the Mongol-Okhotsk Ocean affected the sedimentary basin development remains poorly *** address this issue,we conducted U-Pb dating of detrital zircon deposited sedimentary basins of the central Great Xing’an *** examining the possible provenances of the detrital zircon and the structural controls of the basins,we found that a key sedimentary unit was deposited around Late Jurassic-Early *** provenance was a felsic source in a back-arc setting of an active continental *** findings also suggest the existence of a unified geodynamic setting that affected the coeval development of basins in the northern Great Xing’an Range and the Yanshan fold-thrust belt along the northern margin of North China *** research helps to better understand the complex tectonic processes which shaped the Northeast Asia during the Late Mesozoic.

关键词： Mongol-Okhotsk tectonic domain depositional responses Murui Formation zircon geochemistry tectonics.

Bioinspired Surfaces Derived from Acoustic Waves for On-Demand Droplet Manipulations

在线全文

学校读者我要写书评

暂无评论

Research 2024年第3期2023卷 613-620页

作者： Zhuhao Wu lingyu Sun Hanxu Chen Yuanjin Zhao Department of Rheumatology and Immunology Nanjing Drum Tower HospitalSchool of Biological Science and Medical EngineeringSoutheast UniversityNanjing 210096China Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine Vision and Brain Health)Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhouZhejiang 325001China Chemistry and Biomedicine Innovation Center Nanjing UniversityNanjing 210023China.

The controllable manipulation and transfer of droplets are fundamental in a wide range of chemical reactions and even life processes. Herein, we present a novel, universal, and straightforward acoustic approach to fabricating biomimetic surfaces for on-demand droplet manipulations like many natural creatures. Based on the capillary waves induced by surface acoustic waves, various polymer films could be deformed into pre-designed structures, such as parallel grooves and grid-like patterns. These structured and functionalized surfaces exhibit impressive ability in droplet transportation and water collection, respectively. Besides these static surfaces, the tunability of acoustics could also endow polymer surfaces with dynamic controllability for droplet manipulations, including programming wettability, mitigating droplet evaporation, and accelerating chemical reactions. Our approach is capable of achieving universal surface manufacturing and droplet manipulation simultaneously, which simplifies the fabrication process and eliminates the need for additional chemical modifications. Thus, we believe that our acoustic-derived surfaces and technologies could provide a unique perspective for various applications, including microreactor integration, biochemical reaction control, tissue engineering, and so on.

关键词： straight eliminate acoustics

Hierarchical Spinning of Janus Textiles with Anisotropic Wettability for Wound Healing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research 2024年第1期2023卷 97-105页

作者： Han Zhang lingyu Sun Jiahui Guo Yuanjin Zhao Department of Rheumatology and Immunology Nanjing Drum Tower HospitalSchool of Biological Science and Medical EngineeringSoutheast UniversityNanjingJiangsu 210096China Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine Vision and Brain Health)Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhouZhejiang 325001China

Wound healing and tissue repair are recognized as basic human health problems *** to accelerate the reparative process are focused on developing functional wound ***,we present novel Janus textiles with anisotropic wettability from hierarchical microfluidic spinning for wound *** hydrophilic hydrogel microfibers from microfluidics are woven into textiles for freeze-drying treatment,followed by the deposition of electrostatic spinning nanofibers composed of hydrophobic polylactic acid(PLA)and silver *** electrospun nanofiber layer can be well coupled with the hydrogel microfiber layer to generate Janus textiles with anisotropic wettability due to the roughness of the hydrogel textile surface and the incomplete evaporation of PLA solution when reaching the *** wound treatment with the hydrophobic PLA side contacting the wound surface,the wound exudate can be pumped from the hydrophobic to the hydrophilic side based on the wettability differential derived drainage *** this process,the hydrophobic side of the Janus textile can prevent excess fluid from infiltrating the wound again,preventing excessive moisture and preserving the breathability of the *** addition,the silver nanoparticles contained in the hydrophobic nanofibers could impart the textiles with good antibacterial effect,which further promote the wound healing *** features indicate that the described Janus fiber textile has great application potential in the field of wound treatment.

关键词： silver spinning healing