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Manufacturing task data chain-driven production logistics trajectory analysis and optimization decision making method

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Advances in Manufacturing 2024年第1期12卷 185-206页

作者： Lin ling Zhe-Ming Song Xi Zhang Peng-Zhou Cao xiao-Qiao wang Cong-Hu Liu Ming-Zhou Liu School of Mechanical Engineering Hefei University of TechnologyHefei230009People’s Republic of China Guobo Electronics Co.Ltd. Nanjing211111People’s Republic of China School of Mechanical and Electronic Engineering Suzhou UniversitySuzhou234000AnhuiPeople’s Republic of China Sino-US Global Logistics Institute Shanghai Jiao Tong UniversityShanghai200030People’s Republic of China

Production logistics(PL)is considered as a critical factor that affects the efficiency and cost of production operations in discrete manufacturing *** effectively utilize manufacturing big data to improve PL efficiency and promote job shop floor economic benefits,this study proposes a PL trajectory analysis and optimization decision making method driven by a manufacturing task data chain(MTDC).First,the manufacturing task chain(MTC)is defined to characterize the discrete production process of a *** handle manufacturing big data,the MTC data paradigm is designed,and the MTDC is ***,the logistics trajectory model is presented,where the various types of logistics trajectories are extracted using the MTC as the search engine for the *** on this,a logistics efficiency evaluation indicator system is proposed to support the optimization decision making for the ***,a case study is applied to verify the proposed method,and the method determines the PL optimization decisions for PL efficiency without changing the layout and workshop equipment,which can assist managers in implementing the optimization decisions.

关键词： Production logistics(PL) Logistics trajectory analysis Logistics optimization Data driven Manufacturing task data chain(MTDC)

A Denoiser for Correlated Noise Channel Decoding: Gated-Neural Network

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China Communications 2024年第2期21卷 122-128页

作者： xiao Li ling Zhao Zhen Dai Yonggang Lei School of Electronic and Information Engineering Beihang UniversityBeijing 100191China Beijing Institute of Tracking and Telecommunications Technology BITTT

This letter proposes a sliced-gated-convolutional neural network with belief propagation(SGCNN-BP) architecture for decoding long codes under correlated noise. The basic idea of SGCNNBP is using Neural Networks(NN) to transform the correlated noise into white noise, setting up the optimal condition for a standard BP decoder that takes the output from the NN. A gate-controlled neuron is used to regulate information flow and an optional operation—slicing is adopted to reduce parameters and lower training complexity. Simulation results show that SGCNN-BP has much better performance(with the largest gap being 5dB improvement) than a single BP decoder and achieves a nearly 1dB improvement compared to Fully Convolutional Networks(FCN).

关键词： belief propagation channel decoding correlated noise neural network

Tuning electrochemical water activation over NiIr single-atom alloy aerogels for stable electrochemiluminescence

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Science Bulletin 2024年第15期69卷 2387-2394页

作者： ling ling Mengzhen Xi Hengjia wang Runshi xiao Lirong Zheng Liuyong Hu Wenling Gu Chengzhou Zhu State Key Laboratory of Green Pesticide International Joint Research Center for Intelligent Biosensing Technology and HealthCollege of ChemistryCentral China Normal UniversityWuhan 430079China Hubei Key Laboratory of Plasma Chemistry and Advanced Materials Hubei Engineering Technology Research Center of Optoelectronic and New Energy MaterialsWuhan Institute of TechnologyWuhan 430205China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

The anodic oxygen evolution reaction is a well-acknowledged side reaction in traditional aqueous electrochemiluminescence(ECL) systems due to the generation and surface aggregation of oxygen at the electrode, which detrimentally impacts the stability and efficiency of ECL emission. However, the effect of reactive oxygen species generated during water oxidation on ECL luminophores has been largely overlooked. Taking the typical luminol emitter as an example, herein, we employed NiIr single-atom alloy aerogels possessing efficient water oxidation activity as a prototype co-reaction accelerator to elucidate the relationship between ECL behavior and water oxidation reaction kinetics for the first time. By regulating the concentration of hydroxide ions in the electrolyte, the electrochemical oxidation processes of both luminol and water are finely tuned. When the concentration of hydroxide ions in electrolyte is low,the kinetics of water oxidation is attenuated, which limits the generation of oxygen, effectively mitigates the influence of oxygen accumulation on the ECL strength, and offers a novel perspective for harnessing side reactions in ECL systems. Finally, a sensitive and stable sensor for antioxidant detection was constructed and applied to the practical sample detection.

关键词： Electrochemiluminescence Luminol Water activation Single-atom doping Sensing

Glaucoma drainage device implantation and cyclophotocoagulation in the management of refractory glaucoma after Descemet-stripping automated endothelial keratoplasty

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International Journal of Ophthalmology(English edition) 2024年第2期17卷 257-264页

作者： Min-Shu wang Xue-Chuan Dong Mi-Yun Zheng Xiang Fan Ge-Ge xiao Jing Hong ling-ling Wu Department of Ophthalmology Peking University Third HospitalBeijing 100191China Key Laboratory of Restoration of Damaged Ocular Nerve Beijing 100191China NIMO Ophthalmology Research Institute Beijing 100176China Department of Ophthalmology the First Hospital of PutianTeaching HospitalFujian Medical UniversityPutian 351100Fujian ProvinceChina

AIM:To compare the surgical outcomes of glaucoma drainage device implantation(GDI)and trans-scleral neodymium:YAG cyclophotocoagulation(CPC)in the management of refractory glaucoma after Descemetstripping automated endothelial keratoplasty(DSAEK).METHODS:This retrospective study on observational case series enrolled 29 patients who underwent DSAEK and posterior anti-glaucoma surgery(15 with GDI and 14 with CPC).The main outcome measures were intraocular pressure(IOP),glaucoma surgery success rate(defined as IOP of 6–21 mm Hg without additional anti-glaucoma operation),number of glaucoma medications,endothelial graft status,and best-corrected visual acuity(BCVA).RESULTS:The mean follow-up time was 34.1 and 21.0mo for DSAEK or glaucoma surgeries,both for the GDI and CPC *** groups showed significant IOP reduction after glaucoma *** GDI group presented a significantly higher success rate in IOP control than the CPC group(60%vs 21.4%,P=0.03).Both procedures significantly decreased the number of glaucoma medications(P=0.03).Forty percent and 57%of cases in the GDI and the CPC group,respectively,experienced endothelial graft failure during follow-up(P=0.36).Significantly worse BCVA after surgery was observed in the CPC group but not in the GDI ***:Both GDI and CPC significantly decrease IOP in eyes with glaucoma after *** is preferable to CPC in refractory glaucoma cases after DSAEK,as it manifests a significantly higher success rate for IOP control,similar endothelial graft failure rate,and relatively preserves BCVA than CPC.

关键词： glaucoma drainage device implantation cyclophotocoagulation refractory glaucoma Descemetstripping automated endothelial keratoplasty

Simultaneously enhancing erosion and compression resistance:designing AlCoCrFeNi high-entropy alloy strengthened Ag-based contacts

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Rare Metals 2024年第9期43卷 4476-4492页

作者： xiao-Yang Xue Zhe wang Hui-ling Nie Zhao Yuan Jun wang Chang-Hu Xu Kai Wen Cong-Hao Yu School of Materials Science and Engineering Xi’an Polytechnic University School of Physics Xi’an Jiaotong University Key Laboratory of Pulsed Power Technology School of Electrical and Electronic EngineeringHuazhong University of Science and Technology State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic EngineeringHuazhong University of Science and Technology

Designing microstructures and unveiling dynamic erosion mechanisms remain important challenges for Ag-based contacts. To simultaneously enhance erosion and compression resistance, an Al Co Cr Fe Ni high-entropy alloy(HEA) is introduced into Ag-based materials to fabricate novel Ag-HEA contacts with island-and skeletonrestricted microstructures. The arc erosion experimental results reveal that the skeleton-restricted HEA microstructure is the key factor in reducing the hill and crater morphologies of the contact surface, effectively delaying material transfer between the movable and stationary contacts. The molten bridge evolution and compressive deformation behavior of Ag-HEA contacts with various microstructures are investigated using molecular dynamics(MD) simulations. MD results indicate that the constraint of Ag atom diffusion in the molten pool and the involvement of HEA atoms in the molten bridge are the primary mechanisms for improving erosion resistance. The skeleton-restricted HEA microstructure reduces the total energy and structural stability of the molten bridge system and promotes its fracture and disintegration. Moreover, the synergistic effect of the twin and Lomerz–Cottrell lock structures can hinder dislocation glide, generating dispersed and small-area stacking faults in the Ag matrix and mitigating the concentration of shear strains. Thus, the skeleton-restricted HEA microstructure contributes positively to compression resistance. This study presents a novel approach to designing Ag-based contacts.

关键词： Arc erosion Electrical contact materials High entropy alloys Microstructures Molecular dynamics

Deamidation enables pathogenic SMAD6 variants to activate the BMP signaling pathway

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Science China Life Sciences 2024年第9期67卷 1915-1927页

作者： ling Li Lei Lu Ziqi xiao Jingyi Lv Hefeng Huang Bo Wu Tongjin Zhao Chengtao Li Weimin wang Hongyan wang Obstetrics and Gynecology Hospital State Key Laboratory of Genetic Engineering Institute of Reproduction and Development and Children's Hospital Fudan University Shanghai Key Laboratory of Metabolic Remodeling and Health Institute of Metabolism and Integrative Biology Fudan University Prenatal Diagnosis Center of Shenzhen Maternity & Child Healthcare Hospital Shanghai Medical College Fudan University Department of Pharmacy College of Life Sciences China Jiliang University

The BMP signaling pathway plays a crucial role in regulating early embryonic development and tissue homeostasis. SMAD6 encodes a negative regulator of BMP, and rare variants of SMAD6 are recurrently found in individuals with birth defects. However, we observed that a subset of rare pathogenic variants of SMAD6 consistently exhibited positive regulatory effects instead of the initial negative effects on the BMP signaling pathway. We sought to determine whether these SMAD6 variants have common pathogenic mechanisms. Here, we showed that pathogenic SMAD6 variants accompanying this functional reversal exhibit similar increases in deamidation. Mechanistically, increased deamidation of SMAD6 variants promotes the accumulation of the BMP receptor BMPR1A and the formation of new complexes, both of which lead to BMP signaling pathway activation. Specifically, two residues, N262 and N404, in SMAD6 were identified as the crucial sites of deamidation, which was catalyzed primarily by glutamine-fructose-6-phosphate transaminase 2(GFPT2). Additionally, treatment of cells harboring SMAD6 variants with a deamidase inhibitor restored the inhibitory effect of SMAD6 on the BMP signaling pathway. Conversely,when wild-type SMAD6 was manually simulated to mimic the deamidated state, the reversed function of activating BMP signaling was reproduced. Taken together, these findings show that deamidation of SMAD6 plays a crucial role in the functional reversal of BMP signaling activity, which can be induced by a subset of various SMAD6 variants. Our study reveals a common pathogenic mechanism shared by these variants and provides a potential strategy for preventing birth defects through deamidation regulation, which might prevent the off-target effects of gene editing.

关键词： SMAD6 deamidation BMP signaling pathway GFPT2

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Decentralized Optimal Control and Stabilization of Interconnected Systems With Asymmetric Information

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IEEE/CAA Journal of Automatica Sinica 2024年第3期11卷 698-707页

作者： Na wang xiao Liang Hongdan Li xiao Lu the College of Electrical Engineering and Automation Shandong University of Science and TechnologyQingdao 266000China the School of Automation and Electrical Engineering Linyi UniversityLinyi 276000China the College of Energy Storage Technology Shandong University of Science and TechnologyQingdao 266000China

The paper addresses the decentralized optimal control and stabilization problems for interconnected systems subject to asymmetric *** with previous work,a closed-loop optimal solution to the control problem and sufficient and necessary conditions for the stabilization problem of the interconnected systems are given for the first *** main challenge lies in three aspects:Firstly,the asymmetric information results in coupling between control and estimation and failure of the separation ***,two extra unknown variables are generated by asymmetric information(different information filtration)when solving forward-backward stochastic difference ***,the existence of additive noise makes the study of mean-square boundedness an *** adopted technique is proving and assuming the linear form of controllers and establishing the equivalence between the two systems with and without additive noise.A dual-motor parallel drive system is presented to demonstrate the validity of the proposed algorithm.

关键词： Asymmetric information decentralized control forwardbackward stochastic difference equations interconnected system stalibization

Influence of oxygen-rich hot air composite gas medium on sintering performance and function mechanism

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Journal of Iron and Steel Research International 2024年第5期31卷 1071-1081页

作者： Min Gan Hao-xiang Zheng xiao-hui Fan Zhi-yun Ji Qiang Li Ming Wu Yi-fan wang xiao-long wang Yu-feng Wu Xu-ling Chen Zeng-qing Sun xiao-xian Huang School of Minerals Processing and Bioengineering Central South UniversityChangsha410083HunanChina Shanxi Taigang Stainless Steel Co. Ltd.Taiyuan030003ShanxiChina

Hot air sintering technology is used to improve the quality and production efficiency of sintered ***,the current thick layer condition highlights the disadvantage of the low oxygen potential of the hot air sintering ***,it is considered to use oxygen enrichment sintering to improve the environment of hot air *** sintering,hot air sintering,and oxygen-rich hot air sintering were compared through sintering cup experiments,and the influence of hot air and oxygen-rich hot air on sintering indexes was *** air reduced the vertical sintering velocity,while improved the yield and tumbler ***-rich hot air sintering contributed to improving the vertical sintering velocity while ensuring the quality of sintered ore,thus comprehensively improving production *** the action of hot air,the highest temperature of the sintering layer increased and the high-temperature holding time was *** oxygen enrichment,the combustion efficiency of fuels in the upper layer of materials was promoted,which optimized heat distribution in the middle and lower layers of materials and increased the content of calcium ferrite in the sintered ore,thus strengthening the sintering process.

关键词： Iron ore sintering Hot air sintering Oxygen enrichment Function mechanism

Ultrasound-guided fluid resuscitation versus usual care guided fluid resuscitation in patients with septic shock:a systematic review and meta-analysis

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Emergency and Critical Care Medicine 2024年第2期4卷 82-89页

作者： Zheyuan Chen xiao Han Ying Liu Mengjun wang Beibei wang ling wang Hongxu Jin Emergency Department General Hospital of Northern Theater CommandShenyangLiaoningChina General Hospital of Northern Theater Command China Medical UniversityShenyangLiaoningChina Center for Cardiac Intensive Care Beijing Anzhen HospitalCapital Medical UniversityBeijingChina

Background:Ultrasound is widely used in critical care for fluid resuscitation in critically ill *** conducted a systematic review to assess the relationship between ultrasound-guided fluid resuscitation strategies and usual care in septic ***:We searched PubMed,Embase,Cochrane Library,Web of Science,and registers for randomized controlled trials to evaluate the prognosis of ultrasound-guided fluid resuscitation in patients with septic ***:Twelve randomized controlled studies with 947 participants were ***-guided fluid resuscitation in patients with septic shock was associated with reduced mortality(risk ratio:0.78;95%confidence interval[CI]:0.65 to 0.94;P=0.007)and 24-hour fluid volume(mean differences[MD]:−1.02;95%CI:−1.28 to−0.75;P<0.001),low heterogeneity(I^(2)=29%,I^(2)=0%),and increased dose of norepinephrine(MD:0.07;95%CI:0.02-0.11;P=0.002)and dobutamine dose(MD:2.2;95%CI:0.35-4.04;P=0.02),with low heterogeneity(I^(2)=45%,I^(2)=0%).There was no reduction in the risk of dobutamine use(risk ratio:1.67;95%CI:0.52 to 5.36;P=0.39;I^(2)=0%).Inferior vena cava-related measures reduced the length of hospital stay(MD:−2.91;95%CI:−5.2 to−0.62;P=0.01;low heterogeneity,I^(2)=8%)and length of intensive care unit stay(MD:−2.77;95%CI:−4.51 to−1.02;P=0.002;low heterogeneity,I^(2)=0%).The use of the passive leg-raising test combined with echocardiography to assess fluid reactivity was ***-guided fluid resuscitation did not significantly change the length of the free intensive care unit stay(MD:1.5;95%CI:−3.81 to 6.81;P=0.58;I^(2)=0%).Conclusion:Ultrasound-guided fluid resuscitation in patients with septic shock is beneficial,especially when using inferior vena cava-related measures and the passive leg-raising test combined with echocardiography.

关键词： Meta-analysis Mortality Resuscitation Septic shock Systematic review Ultrasonography