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Clinical analysis of multiple primary gastrointestinal malignant tumors:A 10-year case review of a single-center

World Journal of Gastrointestinal Oncology 2024年第4期16卷 1204-1212页

作者： Cheng-Lou zhu ling-Zhi Peng The First School of Clinical Medicine Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Department of Surgical Oncology Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina

BACKGROUND Multiple primary malignant tumors(MPMTs)was first described by Billroth as early as 1889,with the first report published by Warren and Gates in *** then,numerous cases have been reported.A literature review of 1104269 patients with cancer revealed that the incidence of MPMTs ranged from 0.73 to 11.7%.In recent years,however,there has been a significant upward trend in the incidence of this phenomenon,which may be associated with many different factors,including the advancement of modern diagnostic procedures facilitating the examination and diagnosis of more MPMTs,increased exposure to chemotherapy and radiotherapy that exacerbate the risk of new malignant tumors in patients with cancer,and prolonged survival of patients with cancer allowing sufficient time for the development of new primary *** To analyze the incidence,clinical features,treatment factors,prevalence,and prognosis of patients with MPMTs in the gastrointestinal tract treated in a single ***,we analyzed the different tumor combinations,time interval between the occurrence of tumors,and *** This retrospective cohort study analyzed 8059 patients with pathologically confirmed gastrointestinal malignant tumors treated at the Gansu Province Hospital in Lanzhou,Gansu,China between June 2011 and June *** these,85 patients had *** clinical features,treatment factors,prevalence,and prognosis of this latter cohort were *** The incidence of MPMTs in patients with gastrointestinal malignant tumors was 1.05%(85/8059),including 83 double primary malignant tumors and two triple primary malignant tumors of which 57(67.06%)were synchronous MPMTs(SMPMTs)and 28(32.94%)were metachronous MPMTs(MMPMTs).The most frequent associations were found between the rectum colon cancers within the SMPMT category and the gastric-colon cancers within the MMPMT *** the MMPMTs,the median interval was 53 *** overall 1-,3-and 5-year survival rates f

关键词： Multiple primary malignant tumors Clinical characteristics Gastrointestinal tract Prognosis Epidemiology

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SMSTracker:A Self-Calibration Multi-Head Self-Attention Transformer for Visual Object Tracking

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Computers, Materials & Continua 2024年第7期80卷 605-623页

作者： Zhongyang Wang Hu zhu feng Liu School of Communications and Information Engineering Nanjing University of Posts and TelecommunicationsNanjing210003China

Visual object tracking plays a crucial role in computer *** recent years,researchers have proposed various methods to achieve high-performance object *** these,methods based on Transformers have become a research hotspot due to their ability to globally model and contextualize ***,current Transformer-based object tracking methods still face challenges such as low tracking accuracy and the presence of redundant feature *** this paper,we introduce self-calibration multi-head self-attention Transformer(SMSTracker)as a solution to these *** employs a hybrid tensor decomposition self-organizing multihead self-attention transformermechanism,which not only compresses and accelerates Transformer operations but also significantly reduces redundant data,thereby enhancing the accuracy and efficiency of ***,we introduce a self-calibration attention fusion block to resolve common issues of attention ambiguities and inconsistencies found in traditional trackingmethods,ensuring the stability and reliability of tracking performance across various *** integrating a hybrid tensor decomposition approach with a self-organizingmulti-head self-attentive transformer mechanism,SMSTracker enhances the efficiency and accuracy of the tracking *** results show that SMSTracker achieves competitive performance in visual object tracking,promising more robust and efficient tracking systems,demonstrating its potential to providemore robust and efficient tracking solutions in real-world applications.

关键词： Visual object tracking tensor decomposition transformer self-attention

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Lateral photovoltaic effect in the Ni-SiO_(2)-Si structure with bias

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Optoelectronics Letters 2024年第5期20卷 257-264页

作者： ling Xiang zhu Pengfei zhu Kun SONG Pei LI Xiong School of Mathematics Physics and StatisticsShanghai University of Engineering ScienceShanghai 201600China School of Electrical Engineering Liupanshui Normal UniversityLiupanshui 553004China School of Railway Telecommunication Hunan Technical College of Railway High-speedHengyang 421002China

We designed a clamping device to study lateral photovoltaic effect (LPE) in Ni-SiO_(2)-Si structure with bias due to the appropriate barrier *** LPE has a prominent sensitivity and linearity with 532 nm wavelength *** transient response time is 450μs and the relaxation time is 2 250μs in the Ni-SiO_(2)-Si structure without *** LPE sensitivity has a significant improvement with *** transient response time is 6μs and the relaxion time is 47μs with-7 V bias,not only improving the LPE sensitivity,but also increasing the response speed with *** research shows that the Schottky barrier structure can improve the sensitivity and linearity of LPE with bias effectively,and thus it can be used in position sensitive sensors.

关键词： LPE structure effect

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Generating diverse clothed 3D human animations via a generative model

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Computational Visual Media 2024年第2期10卷 261-277页

作者： Min Shi Wenke feng Lin Gao Dengming zhu School of Control and Computer Engineering North China Electric Power UniversityBeijing 102206China Institute of Computing Technology Chinese Academy of SciencesBeijing 100190China

Data-driven garment animation is a current topic of interest in the computer graphics *** approaches generally establish the mapping between a single human pose or a temporal pose sequence,and garment deformation,but it is difficult to quickly generate diverse clothed human *** address this problem with a method to automatically synthesize dressed human animations with temporal consistency from a specified human motion *** the heart of our method is a twostage ***,we first learn a latent space encoding the sequence-level distribution of human motions utilizing a transformer-based conditional variational autoencoder(Transformer-CVAE).Then a garment simulator synthesizes dynamic garment shapes using a transformer encoder-decoder *** the learned latent space comes from varied human motions,our method can generate a variety of styles of motions given a specific motion *** means of a novel beginning of sequence(BOS)learning strategy and a self-supervised refinement procedure,our garment simulator is capable of efficiently synthesizing garment deformation sequences corresponding to the generated human motions while maintaining temporal and spatial *** verify our ideas *** is the first generative model that directly dresses human animation.

关键词： Transformer garment animation conditional variational autoencoder(CVAE) computer graphics

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Sparse Modal Decomposition Method Addressing Underdetermined Vortex-Induced Vibration Reconstruction Problem for Marine Risers

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China Ocean Engineering 2024年第2期38卷 285-296页

作者： DU Zun-feng zhu Hai-ming YU Jian-xing State Key Laboratory of Hydraulic Engineering Intelligent Construction and Operation School of Civil EngineeringTianjin UniversityTianjin 300350China

When investigating the vortex-induced vibration(VIV)of marine risers,extrapolating the dynamic response on the entire length based on limited sensor measurements is a crucial step in both laboratory experiments and fatigue monitoring of real *** problem is conventionally solved using the modal decomposition method,based on the principle that the response can be approximated by a weighted sum of limited vibration ***,the method is not valid when the problem is underdetermined,i.e.,the number of unknown mode weights is more than the number of known *** study proposed a sparse modal decomposition method based on the compressed sensing theory and the Compressive Sampling Matching Pursuit(Co Sa MP)algorithm,exploiting the sparsity of VIV in the modal *** the validation study based on high-order VIV experiment data,the proposed method successfully reconstructed the response using only seven acceleration measurements when the conventional methods failed.A primary advantage of the proposed method is that it offers a completely data-driven approach for the underdetermined VIV reconstruction problem,which is more favorable than existing model-dependent solutions for many practical applications such as riser structural health monitoring.

关键词： motion reconstruction vortex-induced vibration(VIV) marine riser modal decomposition method compressed sensing

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Histological Features of Uterine Myometrial Dysfunction:Possible Involvement of Localized Inflammation

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Current Medical Science 2024年第3期44卷 633-641页

作者： Sheng-lan zhu Hui-ting ZHANG Yuan-yuan DU Yi JIANG Shao-shuai WANG Wen-cheng DING ling feng National Clinical Research Center for Obstetrics and Gynecology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Obstetrics and Gynecology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

Objective The latest perspective suggests that elevated levels of inflammation and cytokines are implicated in atonic postpartum ***(LPS)has been widely used to induce inflammation in animal ***,this study aimed to induce uterine inflammation using LPS to investigate whether local inflammation triggers dysfunction and atrophy in the myometrium,as well as the potential underlying molecular mechanisms *** In vivo,an animal model was established by intraperitoneal injection of 300μg/kg LPS in rats on gestational day ***-eosin(H&E)staining and Masson staining were employed to determine morphological changes in the rat uterine smooth ***-linked immunosorbent assay(ELISA)was used to detect inflammatory ***,tissue fluorescence,and Western blotting were conducted to assess the expression levels of the uterine contraction-related proteins Toll-like receptor 4(TLR4)and the nuclear factor kappa-B(NF-κB)signaling *** vitro,human uterine smooth muscle cells(HUtSMCs)were exposed to 2μg/mL LPS to further elucidate the involvement of the TLR4/NF-κB signaling pathway in LPS-mediated *** In this study,LPS induced uterine myometrial dysfunction in rats,leading to a disorganized arrangement,a significant increase in collagen fiber deposition,and widespread infiltration of inflammatory *** both in vivo animal models and in vitro HUtSMCs,LPS elevated IL-6,IL-1β,and TNF-αlevels while concurrently suppressing the expression of connexin 43(Cx43)and oxytocin receptor(OXTR).Mechanistically,the LPS-treated group exhibited TLR4 activation,and the phosphorylation levels of p65 and IκBαwere notably *** LPS triggered the TLR4/NF-κB signaling pathway,inducing an inflammatory response in the myometrium and leading to uterine myometrial dysfunction and uterine atony.

关键词： lipopolysaccharide inflammatory response TLR4 NF-κB myometrium

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Selective sintering of magnesia-calcia materials by utilizing hot spots during induction sintering process

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Journal of Iron and Steel Research International 2024年第8期31卷 1914-1922页

作者： Yun-jie Dong Zhou-fu Wang Hao Liu Yan Ma Xi-tang Wang Nian Yi Zhong-feng Xia Yu-xuan zhu Cheng-ji Deng ling Zhang The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina School of Materials and Metallurgy University of Science and Technology LiaoningAnshan 110325LiaoningChina

Magnesia-calcia refractories are widely used in the production process of clean steel due to their excellent high-tem-perature stability,slag resistance and ability to purify molten ***,there are still problems such as difficult sintering and easy ***-calcia materials with various calcium oxide contents were prepared by using induction sintering,and the sintering property combined with the hydration resistance of the materials was *** experimental results showed that the magnesia-calcia materials prepared under induction field had higher density,microhardness and hydration *** particular,the relative density of induction sintered magnesia-calcia materials with 50 mo1%CaO was greater than 98%,and the average grain size of CaO was 4.56μm,which was much larger than that of traditional sintered *** order to clarify the densification and microstructure evolution mechanism of the magnesia-calcia materials,the changes in temperature and magnetic field throughout the sintering process were analyzed by using finite element *** results showed that the larger heating rate and higher sintering temperature under the induction sintering mode were beneficial to the rapid *** addition,the hot spots generated within the material due to the difference in high-temperature electric conductivity between MgO and CaO were the critical factor to realize selective sintering in MgO-CaO system,which provides a novel pathway to solve the problem of difficult sintering and control the microstructure of high-temperature composite material used in the field of high-purity steel smelting.

关键词： Magnesia-calcia material Induction sintering Hot spot Selective sintering Density Microstructure control Hydration resistance

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Improved observation of colonized roots reveals the regulation of arbuscule development and senescence by drought stress in the arbuscular mycorrhizae of citrus

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Horticultural Plant Journal 2024年第2期10卷 425-436页

作者： Xilong Yin Wei Zhang Zengwei feng Guangda feng Honghui zhu Qing Yao College of Horticulture South China Agricultural UniversityKey Laboratory of Biology and Genetic Improvement of Horticultural Crops(South China)Ministry of Agriculture and Rural AffairsGuangdong Province Key Laboratory of Microbial Signals and Disease ControlGuangzhouGuangdong 510642China Key Laboratory of Agricultural Microbiomics and Precision Application Ministry of Agriculture and Rural AffairsGuangdong Provincial Key Laboratory of Microbial Culture Collection and ApplicationKey Laboratory of Agricultural MicrobiomicsState Key Laboratory of Applied Microbiology Southern ChinaGuangdong Microbial Culture Collection Center(GDMCC)Institute of MicrobiologyGuangdong Academy of SciencesGuangzhouGuangdong 510070China

Citrus is the typical mycorrhizal fruit tree species establishing symbiosis with arbuscular mycorrhizal (AM) fungi. However, arbuscule development and senescence in colonized citrus roots, especially in response to drought stress, remain unclear, which is mainly due to the difficulty in clearing and staining lignified roots with the conventional method. Here, we improved the observation of colonized roots of citrus plants with the sectioning method, which enabled the clear observation of AM fungal structures. Furthermore, we investigated the effects of one week of drought stress on arbuscule development and senescence with the sectioning method. Microscopy observations indicated that drought stress significantly decreased mycorrhizal colonization (F%and M%) although it did not affect plant growth performance. Fluorescence probes (WGA 488 and/or Nile red) revealed that drought stress inhibited arbuscule development by increasing the percentage of arbuscules at the early stage and decreasing the percentages of arbuscules at the midterm and mature stages. Meanwhile, drought stress accelerated arbuscule senescence, which was characterized by the increased accumulation of neutral lipids. Overall, the sectioning method developed in this study enables the in-depth investigation of arbuscule status, and drought stress can inhibit arbuscule development but accelerate arbuscule senescence in the colonized roots of citrus plants. This study paves the way to elaborately dissecting the arbuscule dynamics in the roots of fruit tree species in response to diverse abiotic stresses.

关键词： Arbuscular mycorrhizae Citrus Drought stress Arbuscule development Arbuscule senescence Fruit tree species

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Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes

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Eye and Vision 2024年第2期10卷 22-30页

作者： ling Wei Kaiwen Cheng Wenwen He Xiangjia zhu Yi Lu Department of Ophthalmology and Eye Institute Eye and ENT Hospital of Fudan UniversityShanghai 200031China Key Laboratory of Myopia(Fudan University)Key Laboratory of MyopiaShanghai Key Laboratory of Visual Impairment and Restoration National Health CommissionChinese Academy of Medical ScienceShanghai 200031China State Key Laboratory of Medical Neurobiology Fudan UniversityShanghai 200031China

Background:The accuracy of using total keratometry(TK)value in recent IOL power calculation formulas in highly myopic eyes remained ***:Highly myopic patients who underwent uneventful cataract surgery were prospectively enrolled in this prospective comparative *** one month postoperatively,standard deviation(SD)of the prediction errors(PEs),mean and median absolute error(MedAE)of 103 highly myopic eyes were back-calculated and compared among ten formulas,including XGboost,RBF 3.0,Kane,Barrett Universal II,Emmetropia Verifying Optical 2.0,Cooke K6,Haigis,SRK/T,and Wang-Koch modifications of Haigis and SRK/T formulas,using either TK or standard keratometry(K)***:In highly myopic eyes,despite good agreement between TK and K(P>0.05),larger differences between the two were associated with smaller central corneal thickness(P0.05),which both presented smaller MedAEs than others(all P0.05),and statistically larger percentages than the other eight formulas(P<0.05).Conclusions:Highly myopic eyes with thinner corneas tend to have larger differences between TK and *** XGboost enhancement calculator and RBF 3.0 formula using TK showed the most promising outcomes in highly myopic eyes.

关键词： High myopia Total keratometry Cataract surgery IOL power calculation

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Small tracking error correction for moving targets of intelligent electro-optical detection systems

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Frontiers of Mechanical Engineering 2024年第2期19卷 29-44页

作者： Cheng SHEN Zhijie WEN Wenliang zhu Dapeng FAN Mingyuan ling College of Intelligence Science and Technology National University of Defense TechnologyChangsha 410073China

Small tracking error correction for electro-optical systems is essential to improve the tracking precision of future mechanical and defense *** threats,such as“low,slow,and small(LSS)”moving targets,pose increasing challenges to *** core goal of this work is to address the issues,such as small tracking error correction and aiming control,of electro-optical detection systems by using mechatronics drive modeling,composite velocity–image stability control,and improved interpolation filter design.A tracking controller delay prediction method for moving targets is proposed based on the Euler transformation model of a two-axis,two-gimbal cantilever beam coaxial *** tracking error formation is analyzed in detail to reveal the scientific mechanism of composite control between the tracking controller’s feedback and the motor’s velocity–stability *** improved segmental interpolation filtering algorithm is established by combining line of sight(LOS)position correction and multivariable typical tracking fault ***,a platform with 2 degrees of freedom is used to test the *** LSS moving target shooting object with a tracking distance of S=100 m,target board area of A=1 m^(2),and target linear velocity of v=5 m/s is *** show that the optimal method’s distribution probability of the tracking error in a circle with a radius of 1 mrad is 66.7%,and that of the traditional method is 41.6%.Compared with the LOS shooting accuracy of the traditional method,the LOS shooting accuracy of the optimized method is improved by 37.6%.

关键词： electro-optical detection system small tracking error moving target visual servo aiming contro

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