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Joint Optimization of Trajectory and Task Offloading for Cellular-Connected Multi-UAV Mobile Edge Computing

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Chinese Journal of Electronics 2024年第3期33卷 823-832页

作者： Jingming xia Yufeng LIU ling TAN School of Artificial Intelligence Nanjing University of Information Science and Technology Engineering Research Center of Digital Forensics Ministry of Education Nanjing University of Information Science and Technology

Since the computing capacity and battery energy of unmanned aerial vehicle(UAV) are constrained,UAV as aerial user is hard to handle the high computational complexity and time-sensitive *** paper investigates a cellular-connected multi-UAV network supported by mobile edge *** UAVs carrying tasks fly from a given initial position to a termination position within a specified *** handle the large number of tasks carried by UAVs,we propose a energy cost of all UAVs based problem to determine how many tasks should be offloaded to high-altitude balloons(HABs) for computing,where UAV-HAB association,the trajectory of UAV,and calculation task splitting are jointly ***,the formulated problem has nonconvex ***,an efficient iterative algorithm by applying successive convex approximation and the block coordinate descent methods is put ***,in each iteration,the UAV-HAB association,calculation task splitting,and UAV trajectory are alternately ***,for the nonconvex UAV trajectory optimization problem,an approximate convex optimization problem is *** numerical results indicate that the scheme of this paper proposed is guaranteed to converge and also significantly reduces the entire power consumption of all UAVs compared to the benchmark schemes.

关键词： Energy consumption Multi-access edge computing Costs Power demand Autonomous aerial vehicles Iterative algorithms Convex functions

Differences in insomnia-related self-reported outcomes among elderly hospitalized patients

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World Journal of Psychiatry 2024年第5期14卷 686-694页

作者： xia Ding ling-xia Qi Dong-Yun Sun Department of Gangzha General Medical Center The Affiliated Hospital of Nantong UniversityNantong 226000Jiangsu ProvinceChina Department of Anesthesiology and Surgery The Affiliated Hospital of Nantong UniversityNantong 226000Jiangsu ProvinceChina Department of Ophthalmic Surgery Room The Affiliated Hospital of Nantong UniversityNantong 226000Jiangsu ProvinceChina

Insomnia is among the most common sleep disorders *** in older adults is a social and public health *** affects the physical and mental health of elderly hospitalized patients and can aggravate or induce physical *** subjective feelings and providing reasonable and standardized care for elderly hospitalized patients with insomnia are urgent *** To explore the differences in self-reported outcomes associated with insomnia among elderly hospitalized *** One hundred patients admitted to the geriatric unit of our hospital between June 2021 and December 2021 were included in this ***-reported symptoms were assessed using the Athens Insomnia Scale(AIS),Generalized Anxiety Disorder Scale-7(GAD-7),Geriatric Depression Scale-15(GDS-15),Memorial University of Newfoundland Scale of Happiness(MUNSH),Barthel Index Evaluation(BI),Morse Fall Scale(MFS),Mini-Mental State Examination,and the Short Form 36 Health Survey Questionnaire(SF-36).Correlation coefficients were used to analyze the correlation between sleep quality and self-reported *** of insomnia was analyzed using Logistic regression *** Nineteen patients with AIS≥6 were included in the insomnia group,and the incidence of insomnia was 19%(19/100).The remaining 81 patients were assigned to the non-insomnia *** were significant differences between the two groups in the GDA-7,GDS-15,MUNSH,BI,MFS,and SF-36 items(Pling(P<0.05).Subjective well-being and quality of life were poorer in the insomnia group than in the control *** AIS scores positively correlated with the GAD-7,GDS-15,and MFS scores in elderly hospitalized patients with insomnia(P<0.05).Logistic regression analysis showed that GDS-15≥5 was an independent risk factor for ins

关键词： Elderly hospitalized patients Insomnia Self-reported outcomes Symptoms Subjective feelings Correlation

In^(3+)-doped Sr_(2)Fe_(1.5)Mo_(0.5)O_(6−δ)cathode with improved performance for an intermediate-temperature solid oxide fuel cell

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Nano Research 2024年第1期17卷 407-415页

作者： Yumei Ma Lijie Zhang Kang Zhu Binze Zhang Ranran Peng Changrong xia ling Huang State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources College of ChemistryXinjiang UniversityUrumqi 830046China Department of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China

Promoting the oxygen reduction reaction(ORR)is critical for commercialization of intermediate-temperature solid oxide fuel cells(IT-SOFCs),where Sr_(2)Fe_(1.5)Mo_(0.5)O_(6)−δ(SFM)is a promising cathode by working as a mixed ionic and electronic *** this work,doping of In^(3+)greatly increases the oxygen vacancy concentration and the content of adsorbed oxygen species in Sr_(2)Fe_(1.5)Mo_(0.5−x)InxO_(6−δ)(SFMInx),and thus effectively promotes the ORR *** a typical example,SFMIn_(0.1)reduces the polarization resistance(R_(p))from 0.089 to 0.046Ω∙cm^(2)at 800°C,which is superior to those doped with other metal *** addition,SFMIn0.1 increases the peak power density from 0.92 to 1.47 W∙cm^(−2)at 800°C with humidified H_(2)as the fuel,indicating that In3+doping at the Mo site can effectively improve the performance of SOFC cathode material.

关键词： solid oxide fuel cell cathode In3+doping oxygen reduction reaction(ORR) Sr_(2)Fe_(1.5)Mo_(0.5)O_(6-δ)

Novel wood-plastic composite fabricated via modified steel slag:Preparation,mechanical and flammability properties

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International Journal of Minerals,Metallurgy and Materials 2024年第9期31卷 2110-2120页

作者： ling Zhao Kai Zhao Zhenwei Shen Yifan Wang xiaojie xia Hao Zhang Hongming Long School of Metallurgical Engineering Anhui University of TechnologyMa’anshan 243032China School of Civil Engineering and Architecture Anhui University of TechnologyMa’anshan 243032China School of Materials Science and Engineering Anhui University of TechnologyMa’anshan 243032China Key Laboratory of Metallurgical Emission Reduction and Resources Recycling(Anhui University of Technology) Ministry of EducationMa’anshan 243002China

A novel method was developed to enhance the utilization rate of steel slag(SS).Through treatment of SS with phosphoric acid and aminopropyl triethoxysilane(KH550),we obtained modified SS(MSS),which was used to prepare MSS/wood-plastic composites(MSS/WPCs)by replacing talcum powder(TP).The composites were fabricated through melting blending and hot *** mechanical and combustion properties,which comprise heat release,smoke release,and thermal stability,were systematically *** can improve the mechanical strength of the composites through grafting reactions between wood powder and ***,MSS/WPC#50(16wt%MSS)with an MSS-to-TP mass ratio of 1:1 exhibited optimal comprehensive *** with those of WPC#0 without MSS,the tensile,flexural,and impact strengths of MSS/WPC#50 were increased by 18.5%,12.8%,and 18.0%,***,the MSS/WPC#50 sample achieved the highest limited oxygen index of 22.5%,the highest vertical burning rating at the V-1 level,and the lowest horizontal burning rate at 44.2 mm/*** formation of a dense and stable char layer led to improved thermal stability and a considerable reduction in heat and smoke releases of MSS/WPC#***,the partial replacement of TP with MSS slightly compromised the mechanical and flame-retardant properties,possibly due to the weak grafting caused by SS powder *** findings suggest the suitability of MSS/WPCs for high-value-added applications as decorative panels indoors or outdoors.

关键词： modified steel slag wood–plastic composites preparation method mechanical property flame retardant

Ginsenoside Rd Induces Differentiation of Myeloid Leukemia Cells via Regulating ERK/GSK-3βSignaling Pathway

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Chinese Journal of Integrative Medicine 2024年第7期30卷 588-599页

作者： JIANG Yu-xia ZHAO Yan-na YU xiao-ling YIN Li-ming Department of Hematology Tongde Hospital of Zhejiang ProvinceHangzhou310012China Institute of Hematology Research the First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine)Hangzhou310006China

Objective To investigate the role of ginsenoside Rd(GRd)in acute myeloid leukemia(AML)cell *** AML cells were treated with GRd(25,50,100 and 200µg/mL),retinoic acid(RA,0.1g/L)and PD98059(20 mg/mL)for 72 h,cell survival was detected by methylthiazolyldiphenyl-tetrazolium bromide and colony formation assays,and cell cycle was detected by flow *** morphology and differentiation were observed by Wright-Giemsa staining,peroxidase chemical staining and cellular immunochemistry assay,*** protein expression levels of GATA binding protein 1(GATA-1),purine rich Box-1(PU.1),phosphorylated-extracellular signal-related kinase(p-ERK),ERK,phosphorylated-glycogen synthase kinase-3β(p-GSK3β),GSK3βand signal transducer and activator of transcription 1(STAT1)were detected by Western ***-six mice were randomly divided into 3 groups using a random number table:model control group(non-treated),GRd group[treated with 200 mg/(kg·d)GRd]and homoharringtonine(HTT)group[treated with 1 mg/(kg·d)HTT].A tumor-bearing nude mouse model was established,and tumor weight and volume were *** of subcutaneous tumor tissue were observed after hematoxylin and eosin ***1 and GATA-1 expressions were detected by immunohistochemical *** The cell survival was inhibited by GRd in a dose-dependent manner and GRd caused G0/G1 cell arrest(p<0.05).GRd treatment induced leukemia cell differentiation,showing increased expressions of peroxidase and specific proteins concerning erythrogenic or granulocytic differentiation(p<0.05).GRd treatment elicited upregulation of p-ERK,p-GSK-3βand STAT1 expressions in cells,and reversed the effects of PD98059 on inhibiting the expressions of peroxidase,GATA-1 and PU.1(P<0.05).After GRd treatment,tumor weight and volume of mice were decreased,and tumor cells underwent massive apoptosis and necrosis(P<0.05).WT1 level was decreased,and GATA-1 level was significantly increased in subcutaneous tumor ti

关键词： ginsenoside Rd myeloid leukemia survival differentiation extracellular signal-related kinase signaling pathway

Metal nanoparticles for cancer therapy:Precision targeting of DNA damage

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1132-1149页

作者： Qian Chen Chunyan Fang Fan xia Qiyue Wang Fangyuan Li Daishun ling Institute of Pharmaceutics Hangzhou Institute of Innovative MedicineCollege of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Frontiers Science Center for Transformative Molecules School of Chemistry and Chemical EngineeringNational Center for Translational MedicineShanghai Jiao Tong UniversityShanghai 200240China World Laureates Association(WLA)Laboratories Shanghai 201203China Key Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province Hangzhou 310009China

Cancer,a complex and heterogeneous disease,arises from genomic ***,DNA damage-based cancer treatments,including radiotherapy and chemotherapy,are employed in clinical ***,the efficacy and safety of these therapies are constrained by various factors,limiting their ability to meet current clinical *** nanoparticles present promising avenues for enhancing each critical aspect of DNA damage-based cancer *** customizable physicochemical properties enable the development of targeted and personalized treatment *** this review,we delve into the design principles and optimization strategies of metal *** shed light on the limitations of DNA damage-based therapy while highlighting the diverse strategies made possible by metal *** encompass targeted drug delivery,inhibition of DNA repair mechanisms,induction of cell death,and the cascading immune ***,we explore the pivotal role of physicochemical factors such as nanoparticle size,stimuli-responsiveness,and surface modification in shaping metal nanoparticle ***,we present insights into the challenges and future directions of metal nanoparticles in advancing DNA damage-based cancer therapy,paving the way for novel treatment paradigms.

关键词： DNA damage Metal nanoparticles Nucleus-targeting DNA repair inhibition Immune response Size optimization Stimuli-responsiveness Surface modification

Bibliometric analysis of research in epilepsy and comorbid depression from 2014 to 2023

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World Journal of Psychiatry 2024年第6期14卷 985-998页

作者： ling Chen xiao-Hui He xia-ling Li Juan Yang Hao Huang Department of Neurology The Affiliated Hospital of Zunyi Medical UniversityZunyi 563003Guizhou ProvinceChina Department of Neurology Xinqiao Hospital and the Second Affiliated HospitalArmy Medical University(Third Military Medical University)Chongqing 400010China

BACKGROUND Epilepsy and depression have complicated bidirectional *** study aimed to explore the field of epilepsy comorbid with depression in a bibliometric perspective from *** To improve our understanding of epilepsy and depression by evaluating the relationship between epilepsy and depression,bibliometric analyses were *** Epilepsy and depression-related publications from the last decade were retrieved from the Web of Science Core *** conducted bibliometric and visual analysis using VOSviewer and CiteSpace,examining authorships,countries,institutions,journals of publication,co-citations of references,connections between keywords,clusters of keywords,and keywords with citation *** Over the past ten years,we collected 1045 research papers focusing on the field of epilepsy and comorbid *** on epilepsy and depression have shown a general upward trend over time,though with some *** United States,with 287 articles,and the University of Melbourne,contributing 34 articles,were the top countries and institutions,*** addition,in the field of epilepsy and depression,Professor Lee,who has published 30 articles,was the most contributing *** hot topics pay attention to the quality of life in patients with epilepsy and *** We reported that quality of life and stigma in patients with epilepsy comorbid with depression are possible future hot topics and directions in the field of epilepsy and depression research.

关键词： Epilepsy Depression Bibliometrics VOSviewer CiteSpace Visualization analysis

Identification of 1ncRNACTC-564N23.3 in visceral adipose tissue and evidence for its positive effect on human preadipocyte differentiation

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Identification of 1ncRNACTC-564N23.3 in visceral adipose tis...

Electroencephalogram findings in 10 patients with post-stroke epilepsy:A retrospective study

第十三届江浙沪儿科学术会议暨2016年浙江省医学会儿科学学术年会

作者： Chunmei Shi Jian Wang ling xia pang ling Chen Min Zhang FangYan Huang Chenbo Ji Xirong Guo Department of Child Health care Nanjing Maternal and Child Health Hospital Affiliated to Nanjing Medical University Maternal and Child Health InstituteNanjing Maternity and Child Health Care Hospital Nanjing

Objective:Obesity results from numerous,interacting genetic,behavioral,and physiological *** is regulated through the action of a network of transcription factors and *** this regulatory network interfaces with long noncoding RNAs(IncRNAs) remains largely *** this study,we determine to identify the expressions of lncRNACTC-564 N23.3 in visceral adipose tissues and to clarify the roles of lncRNACTC-564 N23.3 in human preadipocyte(HPA) *** and methods:Visceral adipose tissues were collected from patients undergoing surgery,which were divided into two groups based on BMI:obese subjects(BMI ≥28 kg/m2,n=30) and controls(BMI 17 to 27.9 kg/m2,n=12).lncRNACTC-564 N23.3 expression level in visceral adipose tissues was analyzed by realtime *** lncRNACTC-564 N23.3 was stably transfected into human preadipocytes using a lentivirus and effects on adipogenic differentiation were *** indicated by oil red 0 staining and triacylglycerol *** PCR and western blotting analyses indicated the exprssions of adipocyte-specific factors PPAR 7 2,C/EBP-a and ***:The expressions of lncRNACTC-564 N23.3 were higher in obese subjects than in controls(P <0.01).In a pearson correlation analysis,lncRNACTC-564 N23.3 correlated positively with BMI(r = 0.589,P <0.001).lncRNACTC-564 N23.3 was highly expressed in differentiated HPA,and was maximal at day *** expression of lncRNACTC-564 N23.3 in HPA promotes adiopcyte differentiation as reflected by increased oil red 0 staining and triacylglycerol content,and increased expression of key adipogenic genes including PPAR 7 2,C/EBP-a and ***:The results suggest that lncRNACTC-564 N23.3 may be a promising biomarker of obesity in human *** IncRNA may regulate key processes in adipocyte differentiation.

关键词： lncRNA lncRNACTC-564N23 3 HPA adipocytes differentiation obesity

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World Journal of Clinical Cases 2024年第2期12卷 249-255页

作者： Li-Min Wen Ran Li Yan-ling Wang Qing-xia Kong Min xia Clinical Medicine College Jining Medical UniversityJining 272067Shandong ProvinceChina School of Basic Medical Sciences Shandong UniversityJinan 250012Shandong ProvinceChina Department of Neurology The Affiliated Hospital of Jining Medical UniversityJining 272007Shandong ProvinceChina

BACKGROUND Post-stroke epilepsy is a common and easily overlooked complication of acute cerebrovascular ***-term seizures can seriously affect the prognosis and quality of life of ***(EEG)is the simplest way to diagnose epilepsy,and plays an important role in predicting seizures and guiding *** To explore the EEG characteristics of patients with post-stroke epilepsy and improve the detection rate of inter-seizure epileptiform *** From January 2017 to June 2020,10 patients with post-stroke epilepsy in our hospital were *** clinical,imaging,and EEG characteristics were *** stroke location,seizure type,and ictal and interictal EEG manifestations of the patients with post-stroke epilepsy were then retrospectively *** In all 10 patients,epileptiform waves occurred in the side opposite to the stroke lesion during the interictal stage;these manifested as sharp wave,sharp-wave complex,or spike discharges in the anterior head lead of the side opposite to the *** In EEG,epileptiform waves can occur in the side opposite to the stroke lesion in patients with post-stroke epilepsy.

关键词： Post-stroke epilepsy Electroencephalogram Seizure Stroke Slow wave