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论党的组织法规制度法典化

南通大学学报（社会科学版） 2024年第2期40卷 97-109页

作者：祝捷金玲慧武汉大学法学院武汉大学党内法规研究中心

党的组织法规制度法典化是成文法规的必然趋势,也是立法手段在政党规范领域的全新尝试。当前,官方已有明确导向而学界尚未形成规模研究,亟须对党的组织法规法典化展开“全景式”的研究讨论,以减轻或避免其在现实中缺乏实践性的可能。概... 详细信息

党的组织法规制度法典化是成文法规的必然趋势,也是立法手段在政党规范领域的全新尝试。当前,官方已有明确导向而学界尚未形成规模研究,亟须对党的组织法规法典化展开“全景式”的研究讨论,以减轻或避免其在现实中缺乏实践性的可能。概念主体的解构分析、必要性可行性及可见困境的探讨、实践路径的初步拟定等是系统阐释党的组织法规制度法典化不可或缺的部分。以上述内容为引导,可形成“理解党的组织法规制度法典化”到“认可党的组织法规制度法典化”再到“探索党的组织法规制度法典化”的逻辑路径,实现对党的组织法规制度法典化的理性认知,最终为推动党的组织法规制度法典化打造理论基石。

关键词：党内法规党的组织法规制度党的组织法规制度法典化法典化

Clinicopathological Features and Long-Term Prognostic Role of Human Epidermal Growth Factor Receptor-2 Low Expression in Chinese Patients with Early Breast Cancer:A Single-Institution Study

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Biomedical and Environmental Sciences 2024年第5期37卷 457-470页

作者： KONG Zi Qing LIU Li Qun HUANG De Qin WANG Yu Tong LI Jing jie ZHANG Zheng WANG Xi Xi LIU Chuan ling ZHANG Ya Di SHAO Jia Kang ZHU Yi Min CHEN Yi Meng LIU Mei ZHAO Wei Hong Medical School of Chinese PLA Beijing 100853China Department of Medical Oncology the First Medical CenterGeneral Hospital of the Chinese People’s Liberation ArmyBeijing 100853China Nankai University School of Medicine Tianjin 300071China Department of Medical Oncology the Fifth Medical CenterGeneral Hospital of the Chinese People’s Liberation ArmyBeijing 100039China Department of Medical Oncology Xi'an Jiaotong UniversityXi’an 710061ShaanxiChina Department of Pathology the Sixth Medical CenterGeneral Hospital of the Chinese People’s Liberation ArmyBeijing 100037China

Objective This study aimed to comprehensively analyze and compare the clinicopathological features and prognosis of Chinese patients with human epidermal growth factor receptor 2(HER2)-low early breast cancer(BC)and HER2-IHC0 *** Patients diagnosed with HER2-negative BC(N=999)at our institution between January2011 and December 2015 formed our study *** characteristics,association between estrogen receptor(ER)expression and HER2-low,and evolution of HER2 immunohistochemical(IHC)score were ***-Meier method and log-rank test were used to compare the long-term survival outcomes(5-year follow-up)between the HER2-IHC0 and HER2-low *** HER2-low BC group tended to demonstrate high expression of ER and more progesterone receptor(PgR)positivity than HER2-IHC0 BC group(P<0.001).The rate of HER2-low status increased with increasing ER expression levels(Mantel-Haenszelχ^(2)test,P<0.001,Pearson’s R=0.159,P<0.001).Survival analysis revealed a significantly longer overall survival(OS)in HER2-low BC group than in HER2-IHC0 group(P=0.007)in the whole cohort and the hormone receptor(HR)-negative *** were no significant differences between the two groups in terms of disease-free survival(DFS).The discordance rate of HER2 IHC scores between primary and metastatic sites was 36.84%.Conclusion HER2-low BC may not be regarded as a unique BC group in this population-based study due to similar clinicopathological features and prognostic roles.

关键词： HER2 HER2-low Breast cancer Estrogen receptor Trastuzumab deruxtecan

Comparative efficacy and safety of Chinese patent medicines of iron deficiency anemia during pregnancy:A network meta-analysis

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World Journal of Clinical Cases 2024年第18期12卷 3515-3528页

作者： Jia-Chen Zou Xian-ling Jia Hai-Xia Wang Ying-jie Su Jing-Yu Zhu School of Chinese Medicine Weifang Medical UniversityWeifang 261053Shandong ProvinceChina Traditional Chinese Medicine Department Affiliated Hospital of Weifang Medical UniversityWeifang 261031Shandong ProvinceChina

BACKGROUND Iron deficiency anemia(IDA)is a prevalent nutritional disorder during *** studies indicate that incorporating Chinese patent medicines(CPMs)with oral iron(OI)in treating IDA in pregnancy can reduce adverse effects and improve clinical ***,the comparative efficacy of different CPMs remains *** To assess the safety and effectiveness of different CPMs for treating IDA during pregnancy using network *** We conducted a search for randomized controlled trials(RCTs)that combined CPM and OI for IDA treatment in pregnancy,spanning from 2013 to the *** analysis was performed using Rev Man 5.3 and Stata 14.0 on literature that satisfied the quality *** The analysis included 45 RCTs,encompassing 4422 pregnant patients with *** CPMs were examined,including Shengxuebao Mixture,Shengxuening Tablets(SXN),Yiqi Weixue CPMs(YQWX),Jianpi Shengxue CPMs(JPSX),Yiqi Buxue Tablets,and Compound Hongyi Buxue Oral Liquid(FFHY).Findings indicated that FFHY+OI significantly improved the clinical effective ***+OI was most effective in boosting red blood cells counts and hemoglobin ***+OI showed superior results in improving serum ferritin,and SXN+OI was most effective in increasing serum iron ***+OI was optimal in reducing adverse pregnancy outcomes,while YQBX+OI effectively minimized adverse events.A cluster analysis suggested that SXN+OI could be the potentially optimal therapeutic regimen for IDA in *** This study demonstrates that the combination of OI with CPMs offers better outcomes than OI *** on clinical efficacy and other measured outcomes,SXN+OI emerges as the most effective treatment modality for improving the health of pregnant patients with IDA.

关键词： Chinese patent medicine Network meta-analysis Shengxuebao Mixture Shengxuening Tablets Yiqi Weixue Chinese patent medicines Jianpi Shengxue Chinese patent medicines Yiqi Buxue Tablets Compound Hongyi Buxue Oral Liquid

Application of PDCA in improving hand hygiene compliance and nosocomial infection quality in orthopedics

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Frontiers of Nursing 2024年第3期11卷 327-336页

作者： Ya-Ping Su Rui-ling Li Yuan-Yuan Wang Yu-Rui Zhang Ya-jie Ji Nursing Teaching and Research Department School of Nursing and HealthHenan UniversityKaifengHenan 475004China Department of Continuing Education The First Affiliated Hospital of Henan UniversityKaifengHenan 475000China

Objective:To explore the effect of the Plan-Do-Check-Action(PDCA)cycle on hand hygiene and nosocomial infection quality of or thopedic medical ***:The whole year of 2021 was selected to monitor the quality of hand hygiene and ***-up monitoring and real-time recording during the period of morning shift and medical operation concentration time,and compare the compliance of hand hygiene before and after implementation,and evaluate the quality of nosocomial ***:The hand hygiene compliance of doctors and nurses in stage P was 82%.The compliance of medical staff in stage D was 93%.The compliance of stage C was 94%and that of stage A was 95%.The quality score of hospital self-examination nosocomial infection was also significantly ***:The PDCA management cycle can effectively improve the compliance of hand hygiene and the nosocomial infection quality,which is wor thy of circulatory application in or thopedic nosocomial infection quality control,especially improving the quality of hand hygiene.

关键词： hand hygiene quality improvement PDCA nosocomial infection infection control nursing management

时速400 km高速列车通过隧道诱发车体横向振动的气动机制研究

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隧道建设（中英文） 2024年第7期44卷 1477-1490页

作者：谢新雨盖杰马瑶梅元贵兰州交通大学甘肃省轨道交通力学应用工程实验室甘肃兰州730070 中车长春轨道客车股份有限公司国家轨道客车工程研究中心吉林长春130062

为研究列车以更高速度通过双线隧道时,由于列车和隧道形成的几何空间为非对称空间,列车两侧空气非对称流动,隧道内复杂的压力环境作用至车体两侧和列车尾涡引起的车厢两侧压力变化、列车车体表面压力波动与气动力相互关系和车体振动频... 详细信息

为研究列车以更高速度通过双线隧道时,由于列车和隧道形成的几何空间为非对称空间,列车两侧空气非对称流动,隧道内复杂的压力环境作用至车体两侧和列车尾涡引起的车厢两侧压力变化、列车车体表面压力波动与气动力相互关系和车体振动频谱特征,采用三维非定常可压缩流动N-S方程和IDDES湍流模型,建立时速400 km高速列车1∶1的8节编组空气动力学仿真模型,使用重叠网格技术模拟列车与隧道之间的相对运动方法。研究结果表明:1)隧道内行驶的列车在隧道压力波作用下会使车厢两侧出现压差和侧向力幅值的大范围变化,且变化程度由头车向尾车逐渐增大;2)列车在隧道内运行时的尾流区存在1对反向涡旋;3)尾车明线段涡脱落主频率为2.002 Hz,隧道内运行时,涡脱落频率为3.003 Hz;4)列车在明线或隧道内运行,车体气动侧向力和摇头力矩引起的车体振动频率为2.002 Hz。

关键词：时速400 km高速列车双线隧道列车车体表面压力波动车体气动侧向力摇头力矩尾流涡脱频率横向振动

Effect and Safety of Herbal Medicine Foot Baths in Patients with Diabetic Peripheral Neuropathy:A Multicenter Double-Blind Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第3期30卷 195-202页

作者： HUANG Hao-yue LIN Yu-ping WEI Hua FU Yu ZHOU Yue-hong FANG Zhao-hui QIU Xiao-tang WANG Mei LI Qing-bo LI Shan-shan WANG Shi-dong DAI Fang LIU Zhen-jie ZHAO ling WEN Jian-xuan WU Li-yan ZENG Hui-yan ZHANG Jin-ming LU Qi-yun HE Liu SONG Wei SUN Lu LUO Lu-lu HE Jia-li XIE Wen-wen LIANG Qing-shun HUANG Yuan ZHU Sheng-ling LONG jie-er GAO Zhi-juan WEN Ze-huai LI Chun-ji OUYANG Wen-wei LI Geng WU Ming-hui LI An-xiang HUANG Jin-zhu Sanjoy K Paul TANG Xian-yu FAN Guan-jie Department of Endocrinology Guangdong Provincial Hospital of Chinese MedicineGuangzhou510120China The Second Clinical College of Guangzhou University of Chinese Medicine Guangzhou510120China Department of Endocrinology The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou510120China Guangdong Provincial Academy of Chinese Medical Sciences Guangzhou510120China Department of Endocrinology The First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou450000China Department of Endocrinology Liuyang Hospital of Chinese MedicineChangsha410000China Department of Endocrinology The First Affiliated Hospital of Anhui University of Chinese MedicineHefei230000China Department of Endocrinology Hainan Provincial Hospital of Traditional Chinese MedicineHaikou570100China Department of Endocrinology The Affiliated Hospital of Liaoning University of Traditional Chinese MedicineShenyang110000China Department of Geriatric Luoyang No.1 Hospital of Traditional Chinese MedicineLuoyangHenan Province471000China Department of Endocrinology The Second Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Department of Endocrinology Beijing University of Chinese Medicine Affiliated Dongzhimen HospitalBeijing100000China Department of Endocrinology The First Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Melbourne EpiCentre The University of Melbourne and Melbourne HealthMelbourne3013Australia

Objective:To evaluate the effect and safety of foot baths with Tangbi Waixi Decoction(TW)in treating patients with diabetic peripheral neuropathy(DPN).Methods:It is a multicenter double-blinded randomized controlled *** with DPN were recruited between November 18,2016 and May 30,2018 from 8 hospitals in *** patients received basic treatments for glycemic *** received foot baths with TW herbal granules either 66.9 g(intervention group)or 6.69 g(control group)for 30 min once a day for 2 weeks and followed by a 2-week rest,as a therapeutic *** the Toronto Clinical Scoring System total score(TCSS-TS)6 points,the patients received a total of 3 therapeutic courses(for 12 weeks)and were followed up for 12 *** primary outcome was change in TCSS-TS score at 12 and 24 *** outcomes included changes in bilateral motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of the median and common peroneal *** was also ***:Totally 632 patients were enrolled,and 317 and 315 were randomized to the intervention and control groups,*** the 12-week intervention,patients in both groups showed significant declines in TCSSTS scores,and significant increases in MNCV and SNCV of the median and common peroneal nerves compared with pre-treatment(P0.05),and no serious adverse event was related with ***:Treatment of TW foot baths was safe and significantly benefitted patients with DPN.A low dose of TW appeared to be more effective than a high dose.(Registry *** CTR-IOR-16009331)

关键词： diabetic peripheral neuropathy herbal medicine foot baths Chinese medicine randomized controlled trial Tangbi Waixi Decoction

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基于群决策-云理论的装备保障能力评估

科学技术与工程 2024年第11期24卷 4488-4494页

作者：李改灵黄韬李昂骏陆军军事交通学院天津300161

针对装备保障效能评估的复杂性、随机性和模糊性问题,建立了基于群决策-云理论的装备保障能力评估模型。首先,基于装备保障任务的需求,构建了装备保障能力评估指标体系;再利用序关系-群决策方法计算各级指标权重,计算过程简单快捷、更... 详细信息

针对装备保障效能评估的复杂性、随机性和模糊性问题,建立了基于群决策-云理论的装备保障能力评估模型。首先,基于装备保障任务的需求,构建了装备保障能力评估指标体系;再利用序关系-群决策方法计算各级指标权重,计算过程简单快捷、更能体现群体决策;最后,将云理论引入装备保障能力评估中,能够实现定性概念与定量数据间的合理转换,清晰准确地表达了层级指标的聚合过程,有效解决了评估过程中的模糊性和随机性。实例表明:该方法计算简单、逻辑关系清楚、计算结果与客观实际相符,可为装备保障效能评估提供一种科学、客观的方法,为保障资源配置提供科学依据。

关键词：序关系分析法群决策云理论装备保障

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基于CNN-BiGRU的恶意域名检测方法

计算机应用与软件 2024年第6期41卷 336-341页

作者：林梓宇凌捷广东工业大学计算机学院广东广州510006

恶意域名检测对于防范僵尸网络等网络攻击具有重要意义。该文提出一种基于CNN和BiGRU的恶意域名检测方法CNN-BiGRU-Focal,利用卷积神经网络和双向门控循环单元网络来进行特征的融合学习,并引入改进的Focal Loss函数用以解决数据不平衡... 详细信息

恶意域名检测对于防范僵尸网络等网络攻击具有重要意义。该文提出一种基于CNN和BiGRU的恶意域名检测方法CNN-BiGRU-Focal,利用卷积神经网络和双向门控循环单元网络来进行特征的融合学习,并引入改进的Focal Loss函数用以解决数据不平衡问题。与LSTM、CNN、GRU、ATT-CNN-BiLSTM方法的对比实验表明,文章方法在多分类实验中检测准确率分别提高1.43百分点、2.89百分点、1.27百分点、2.43百分点,在二分类实验中检测准确率分别提高0.19百分点、0.12百分点、1.41百分点、0.3百分点。实验表明CNN-BiGRU-Focal方法在恶意域名的检测上有着更好的性能。

关键词：域名生成算法深度学习卷积神经网络双向门控循环单元网络

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基于遗传算法-序列二次规划的磁共振被动匀场优化方法

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浙江大学学报（工学版） 2024年第6期58卷 1305-1314页

作者：赵杰刘锋夏灵范一峰杭州医学院医学影像学院浙江杭州310053 昆士兰大学信息技术与电气工程学院昆士兰布里斯班4072 浙江大学生物医学工程教育部重点实验室浙江杭州310027

为了解决磁共振成像(MRI)系统中固有的主磁场(B0)不均匀的问题,提出遗传算法-序列二次规划(GASQP)算法,以提高7 T磁共振的主磁场均匀性.从被动匀场数学模型的角度出发,该混合算法利用GA算法获得稳定的初始解,实现主磁场的第1次优化,再通... 详细信息

为了解决磁共振成像(MRI)系统中固有的主磁场(B0)不均匀的问题,提出遗传算法-序列二次规划(GASQP)算法,以提高7 T磁共振的主磁场均匀性.从被动匀场数学模型的角度出发,该混合算法利用GA算法获得稳定的初始解,实现主磁场的第1次优化,再通过SQP算法的快速求解,在较少的时间内实现主磁场的第2次优化,同时提高磁共振主磁场的均匀性.采用正则化方法减少磁场均匀所需的铁片质量,并且获得稀疏的铁片分布.在仿真建模的案例研究中,7 T磁共振裸磁场均匀度可以从462×10-6优化到4.5×10-6,并且在匀场空间上仅消耗0.8 kg的铁片.相比于传统的GA优化方法,新方案的磁场均匀性提高了96.7%,总铁片消耗质量减少了85.7%.实验结果表明,GA-SQP算法比其他优化算法具有更强的鲁棒性和竞争力.

关键词：磁共振成像被动匀场遗传算法-序列二次规划(GA-SQP) 正则化方法非线性优化