检索结果-南通市图书馆

Sphingosine kinase 1 dependent protein kinase C-δ activation plays an important role in acute liver failure in mice

World Journal of Gastroenterology 2015年第48期21卷 13438-13446页

作者： Yan-Chang Lei ling-ling yang Wen Li Pan Luo Department of Infectious Diseases Zhejiang Hospital Infectious Disease Hospital of Nanchang University

AIM: To investigate the role of protein kinase C(PKC)-δ activation in the pathogenesis of acute liver failure(ALF) in a well-characterized mouse model of D-galactosamine(D-Gal N)/lipopolysaccharide(LPS)-induced ***: BALB/c mice were randomly assigned to five groups, and ALF was induced in mice by intraperitoneal injection of D-Ga IN(600 mg/kg) and LPS(10 μg/kg). Kaplan-Meier method was used for survival analysis. Serum alanine aminotransferase(ALT) and aspartate aminotransferase(AST) levels at different time points within one week were determined using a multiparameteric analyzer. Serum levels of high-mobility group box 1(HMGB1), tumor necrosis factor(TNF)-α, interleukin(IL)-1β, IL-6, and IL-10 as well as nuclear factor(NF)-κB activity were determined by enzyme-linked immunosorbent assay. Hepatic morphological changes at 36 h after ALF induction were assessed by hematoxylin and eosin staining. Expression of PKC-δ in liver tissue and peripheral blood mononuclear cells(PBMCs) was analyzed by Western ***: The expression and activation of PKC-δ were up-regulated in liver tissue and PBMCs of mice with D-Gal N/LPS-induced ALF. Inhibition of PKC-δ activation with rottlerin significantly increased the survival rates and decreased serum ALT/AST levels at 6, 12 and 24 h compared with the control group(P < 0.001). Rottlerin treatment also significantly decreased serum levels of HMGB1 at 6, 12, and 24 h, TNF-α, IL-6 and IL-1 β at 12 h compared with the control group(P < 0.01). The inflammatory cell infiltration and necrosis in liver tissue were also decreased in the rottlerin treatment group. Furthermore, sphingosine kinase 1(Sph K1) dependent PKC-δ activation played an important role in promoting NF-κB activation and inflammatory cytokine production in ***: Sph K1 dependent PKC-δ activation plays an important role in promoting NF-κB activation and inflammatory response in ALF, and inhibition of PKC-δ activation might be a potential therapeutic strat

关键词： Acute liver failure Protein kinase C-δ Sphingosine kinase 1 Nuclear factor-κB

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of Sintering Time on Structure and Properties in CuO-doping KNN-LS-BF Piezoelectric Ceramics

引用

Journal of Wuhan University of Technology(Materials Science) 2019年第2期34卷 308-311页

作者：王华 ZHAI Xia XU Jiwen yang ling School of Materials Science and Engineering Guilin University of Electronic Technology

The 0.6 mol% CuO-doping 0.996(0.95 Na_(0.5)K_(0.5)NbO_3-0.05 LiSbO_3)-0.004 FeBiO_3(KNN-LSBF-CuO) piezoelectric ceramics were synthesized by a solid-state reaction technique, and the structure and piezoelectric properties dependence of sintering time in KNN-LS-BF-CuO ceramics were studied. It is found that all the samples sintered for various time are perovskite structure mixed with orthorhombic symmetry phase and tetragonal phase, but the sintering time has significant influences on the crystalline and properties. When the sintering time increases from 2 hours to 6 hours, the grain of KNN-LS-BF-CuO ceramics becomes more homogeneous and more tight-arrangement. The experimental results reveal that the longer sintering time than 4 hours is beneficial for improving partial properties, such as d_(33), tgδ, and Q_m, but is adverse to ε_r and k_p, the KNNLS-BF-CuO ceramics with optimum properties can be synthesized for 6 hours at 1 060 ℃.

关键词： piezoelectric ceramics KNN-LS-BF CuO-doping sintering time

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Elasto-plastic analysis of the surrounding rock mass in circular tunnel based on the generalized nonlinear unified strength theory

引用

International Journal of Mining Science and Technology 2016年第5期26卷 819-823页

作者： Huang Xiujie Zhang Jixun yang ling yang Shikou Wang Xingli College of Water Conservancy and Hydropower Hohai University Nanjing 210098 China College of Hydrology and Water Resources Hohai University Nanjing 210098 China

The present paper aims to establish a versatile strength theory suitable for elasto-plastic analysis of underground tunnel surrounding rock. In order to analyze the effects of intermediate principal stress and the rock properties on its deformation and failure of rock mass, the generalized nonlinear unified strength theory and elasto-plastic mechanics are used to deduce analytic solution of the radius and stress of tunnel plastic zone and the periphery displacement of tunnel under uniform ground stress field. The results show that: intermediate principal stress coefficient b has significant effect on the plastic range,the magnitude of stress and surrounding rock pressure. Then, the results are compared with the unified strength criterion solution and Mohr–Coulomb criterion solution, and concluded that the generalized nonlinear unified strength criterion is more applicable to elasto-plastic analysis of underground tunnel surrounding rock.

关键词： Circular tunnel Generalized Hoek–Brown strength criterion Generalized nonlinear unified strength criterion Intermediate principal stress Elasto-plastic stress and displacement

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Indirect somatic embryogenesis and regeneration of Fraxinus mandshurica plants via callus tissue

引用

Journal of Forestry Research 2021年第4期32卷 1613-1625页

作者： yang Liu Cheng Wei Hao Wang Xiao Ma Hailong Shen ling yang State Key Laboratory of Tree Genetics and Breeding Northeast Forestry UniversityHarbin 150040People’s Republic of China State Forestry and Grassland Administration Engineering Technology Research Center of Native Tree Species Harbin 150040People’s Republic of China

Somatic embryogenesis of Fraxinus mandshurica has the problems of low somatic embryo(SE) yield,unsynchronized SE development,and a high percentage of deformed *** aimed to improve *** SE production by synchronizing SE development,improving SE quality,and inducing root formation to obtain complete regenerated *** of immature zygotic embryos of *** were induced to form callus and then *** SE induction percentage from explants differed among 32 mother trees,and the one with the highest SE induction percentage(29.8%) was used for further *** highest callus induction percentage was94.2% on 1/2-strength Murashige and Skoog medium(MS1/2)supplemented with 0.15 mg·L^(-1) naphthalene acetic *** highest callus proliferation coefficient(240.5) was obtained on McCown's Woody Plant Medium containing 0.1 mg·L^(-1)6-benzyl adenine and 0.15 mg·L^(-1) 2,4-dichlorophenoxyacetic *** highest number of SEs(1020.5 g~(-1) fresh weight) was obtained on MS1/2 medium supplemented with1 mg·L^(-1) *** highest number of cotyledon embryos(397/g fresh weight) was obtained by incubating materials on medium containing 1 mg·L^(-1) abscisic acid and then applying a drying *** cotyledon embryos were milky white,uniformly sized(average length 4.7 mm),and 80% of them were *** SE rooting percentage on 1/2 MS medium containing 0.01 mg·L^(-1) NAA was 37.5%.Overall,the germination percentage of SEs was 26.4%,and complete regenerated plants were obtained after transplanting and *** results provide more possibilities for the preservation and breeding of ***.

关键词： Fraxinus mandshurica Somatic embryogenesis Callus induction Cell differentiation Plant regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multi-Antenna Jammer Assisted Covert Communications in Data Collected IoT with NOMA

引用

China Communications 2023年第5期20卷 217-231页

作者： Liwei Tao Weiwei yang Xingbo Lu Ruiqian Ma ling yang Yi Song Mechanical Engineering Department Army Academy of Artillery and Air Defense of PLAHefei 230031China College of Communication Engineering Army Engineering University of PLANanjing 210007China Academy of Military Sciences of PLA Beijing 100091China College of Electronic Engineering National University of Defense Technology of PLAHefei 230037China College of Railway Transportation Hunan University of TechnologyZhuzhou 412000China School of Physics and Electronic Electrical Engineering Huaiyin Normal UniversityHuaian 223399China

In this paper,we investigate covert communications in data collected IoT with NOMA,where the paired sensor nodes S_(m) and S_(n) transmit covert messages to a legitimate receiver(Bob)in the presence of a Warden(Willie).To confuse the detection at Willie,an extra multi-antenna friendly jammer(Jammer)has been employed to transmit artificial noise(AN)with random *** on the CSI of Willie is available or not at Jammer,three AN transmission schemes,including null-space artificial noise(NAN),transmit antenna selection(TAS),and zeroforcing beamforming(ZFB),are ***,the closed-form expressions of expected minimum detection error probability(EMDEP)and joint connection outage probability(JCOP)are derived to measure covertness and reliability,***,the maximum effective covert rate(ECR)is obtained with a given covertness *** numerical results show that ZFB scheme has the best maximum ECR in the case of the number of antennas satisfies N>2,and the same maximum ECR can be achieved in ZFB and NAN schemes with N=***,TAS scheme also can improve the maximum ECR compared with the benchmark scheme(i.e.,signal-antenna jammer).In addition,a proper NOMA node pairing can further improve the maximum ECR.

关键词： IoT covert communications NOMA node pairing multi-antenna jammer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Spinor Approach to the SU(2) Clebsch-Gordan Coefficients

引用

Communications in Theoretical Physics 2019年第6期71卷 663-669页

作者： ling-Di yang Fa-Min Chen Department of Physics Beijing Jiaotong University

We review the irreducible representation of an angular momentum vector operator constructed in terms of spinor algebra. We generalize the idea of spinor approach to study the coupling of the eigenstates of two independent angular momentum vector operators. Utilizing the spinor algebra, we are able to develop a simple way for calculating the SU(2) Clebsch-Gordan(CG) coefficients. The explicit expression for the SU(2) CG coefficients is worked out, and some simple physical examples are presented to illustrate the spinor approach.

关键词： Clebsch-Gordan coefficients spinors representations

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of Winglet Geometry Arrangement and Incidence on Tip Clearance Control in a Compressor Cascade

引用

Journal of Thermal Science 2014年第4期23卷 381-390页

作者： HAN Shaobing ZHONG Jingjun LU Huawei KAN Xiaoxu yang ling Marine Engineering College Dalian Maritime University

An experimental study is conducted to investigate the influences of blade tip winglet on the flow field of a compressor cascade. The tests are performed in a low speed linear cascade with stationary endwall, with three blade tip configurations, including the baseline tip, the suction-side winglet tip and the pressure-side winglet tip. The fiowfield downstream of the cascade is measured using five-hole probe, from which the three-dimensional velocity field, vorticity field and pressure field are obtained. Static pressure measurements are made on the endwall above the blade row using pressure taps embedded in the plywood endwall. All measurements are made at both design and off-design conditions for tip clearance level of about 2 percent of the blade chord. The results revealed the incidence variation significantly affects the secondary flow and the associated loss field downstream of the cascade, where the tip leakage vortex and passage vortex exist as the major contributors on the field. The winglet geometry arrangements can change the trajectory of the tip leakage vortex. The suction-side winglet tip blade provides a lower overall total pressure loss coefficient when compared to the baseline tip blade and pressure-side winglet tip blade at all incidence angles.

关键词： blade tip winglet compressor cascade incidence tip clearance flow

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Granulation by spray coating aqueous solution of ammonium sulfate to produce large spherical granules in a fluidized bed

引用

Particuology 2013年第5期11卷 483-489页

作者： Guanda Wang ling yang Rui Lan Tingjie Wang Yong Jin Department of Chemical Engineering Tsinghua University

Spherical 2-4mm granules of ammonium sulfate （NH4）2SO4 are promising fertilizer for practical use, though only much smaller grains are being produced in industry. This work used coating granulation to produce large spherical granules of （NH4）2SO4 in a fluidized bed by spraying its aqueous solution onto 0.9-1.6 mm （NH4）2SO4 core particles. However, the overall coating efficiency was only 58% due to loss as dust by attrition of（NH4）2SO4 in the vent gas. By adding CaCO3 or SiO2 particles into the feed solution, the coating efficiency was increased to over 90%. This increase in coating efficiency was due to a change in the crystallization mechanism of（NH4）2SO4. The added CaC03 or Si02 particles provided a heterogeneous surface that induced （NH4）2S04 to crystallize uniformly to form a more compact structure less susceptible to attrition.

关键词： Ammonium sulfateSpray coatingGranulationFluidized bedHeterogeneous crystallization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison of QTLs for rice seedling morphology under different water supply conditions

引用

Journal of Genetics and Genomics 2008年第8期35卷 473-484页

作者： Bingsong Zheng ling yang Chuanzao Mao Youjun Huang Ping Wu School of Forestry ＆ Biotechnology Zhejiang Forestry University Hangzhou 311300 China State Key Laboratory of Plant Physiology and Biochemistry College of Life Sciences Zhejiang University Hangzhou 310058 China College of Chemistry and Life Sciences Zhejiang Normal University Jinhua 321004 China

The variation of seedling characteristics under different water supply conditions is strongly associated with drought resistance in rice （Oryza sativa L.） and a better elucidation of its genetics is helpful for improving rice drought resistance. Ninety-six doubled-haploid （DH） rice lines of an indica and japonica cross were grown in both flooding and upland conditions and QTLs for morphological traits at seedling stage were examined using 208 restriction fragment length polymorphism （RFLP） and 76 microsatellite （SSR） markers. A total of 32 putative QTLs were associated with the four seedling traits： average of three adventitious root lengths （ARL）, shoot height （SH）, shoot biomass （SW）, and root to shoot dry weight ratio （RSR）. Five QTLs detected were the same under control and upland conditions. The ratio between the mean value of the seedling trait under upland and flooding conditions was used for assessing drought tolerance. A total of six QTLs for drought tolerance were detected. Comparative analysis was performed for the QTLs detected in this case and those reported from two other populations with the same upland rice variety Azucena as parent. Several identical QTLs for seedling elongation across the three populations with the positive alleles from the upland rice Azucena were detected, which suggests that the alleles of Azucena might be involved in water stress-accelerated elongation of rice under different genetic backgrounds. Five cell wall-related candidate genes for OsEXPI, OsEXP2, OsEXP4, EXT, and EGase were mapped on the intervals carrying the QTLs for seedling traits.

关键词： Oryza sativa L. QTLs mapping seedling morphology flooding condition upland condition

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Swelling and diffusion model of a hydrophilic film coating on controlled-release urea particles

引用

Particuology 2017年第1期15卷 73-82页

作者： ling yang Di An Ting-Jie Wang Chengyou Kan Yong Jin Department of Chemical Engineering Tsinghua University Beijing 100084. China

Controlled-release urea was fabricated by coating urea particles with a polymer latex in a fluidized bed. The latex film coated on the urea particle surface was hydrophilic and swelled in water. The film swelling in water and urea solution and properties of the swollen film were studied. The film swelling in urea solution followed the Lagergren＇s pseudo-first order kinetics with the swelling coefficient depending on the film material and experimental conditions. The effects of swelling on film structure and permeability were studied. The film permeability coefficient decreased with increasing swelling ratio with an approx- imately linear relationship. Based on the film formation process and structure of the swollen film. a film structure model consisting of dense and swollen phases was proposed. The permeability coefficient of the spherical film and cumulative release of urea from the coated particles were calculated from the swelling ratio of the spherical film. which was determined from the expansion curve of the coated particle during the release process, The calculated and measured release curves agreed well, This research indicates that the swelling of the hydrophilic film and the controlled-release mechanism are important factors in the development of controlled-release urea.

关键词： Coating Controlled -release Particle Permeability Swelling Urea

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：