检索结果-南通市图书馆

2016至2020年杭州地区无偿献血人群HIV感染状况分析

在线全文

学校读者我要写书评

暂无评论

中国现代医生 2024年第14期62卷 11-14页

作者：励晓涛董杰凌霞祝宏吴丹霄浙江省血液中心浙江杭州310006 浙江省血液安全研究重点实验室浙江杭州310006

目的了解杭州地区无偿献血人群HIV感染状况,为本地区降低HIV经输血传播风险,制定有效献血者招募及艾滋病防控策略提供数据支持。方法采用酶联免疫吸附试验(enzyme-linked immunosorbent assay,ELISA)和病原体核酸检测技术(nucleic acid ... 详细信息

目的了解杭州地区无偿献血人群HIV感染状况,为本地区降低HIV经输血传播风险,制定有效献血者招募及艾滋病防控策略提供数据支持。方法采用酶联免疫吸附试验(enzyme-linked immunosorbent assay,ELISA)和病原体核酸检测技术(nucleic acid testing,NAT)对2016年1月至2020年12月杭州地区902847例无偿献血者标本进行抗HIV-Ⅰ/Ⅱ抗体/抗原和HIVRNA检测。抗-HIV抗体/抗原或HIVRNA反应性标本送杭州市疾病控制中心进一步采用Western blot法和NAT进行确认。结果2016年1月至2020年12月杭州地区共检测HIV确证阳性103例,阳性检出率为0.01%,其中101例ELISA和NAT筛查均为阳性反应,2例ELISA筛查为阴性反应,NAT为阳性反应。103例感染者中,以男性(91.26%,94/103)、18~35岁(69.90%,72/103)、初次献血者(68.93%,71/103)为主。2016至2020年献血者HIV阳性率呈逐年下降趋势(χ^(2)=7.181,P=0.007)。男女献血者HIV阳性率各年的差异无统计学意义(χ^(2)=10.336,P=0.350;χ^(2)=0.653,P=0.957)。各年龄组献血者HIV阳性率各年的差异无统计学意义(χ^(2)=6.378,P=0.173;χ^(2)=2.318,P=0.678;χ^(2)=5.284,P=0.259;χ^(2)=9.183,P=0.057)。结论近5年HIV感染在杭州市无偿献血人群中呈低流行水平,但仍存在感染风险,应加强在低危人群中招募献血者并且应采用先进的检测技术,选择合适的检测策略,保证血液安全。

关键词：献血者 HIV感染酶联免疫吸附试验核酸检测

Joint Optimization of Trajectory and Task Offloading for Cellular-Connected Multi-UAV Mobile Edge Computing

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Electronics 2024年第3期33卷 823-832页

作者： Jingming xia Yufeng LIU ling TAN School of Artificial Intelligence Nanjing University of Information Science and Technology Engineering Research Center of Digital Forensics Ministry of Education Nanjing University of Information Science and Technology

Since the computing capacity and battery energy of unmanned aerial vehicle(UAV) are constrained,UAV as aerial user is hard to handle the high computational complexity and time-sensitive *** paper investigates a cellular-connected multi-UAV network supported by mobile edge *** UAVs carrying tasks fly from a given initial position to a termination position within a specified *** handle the large number of tasks carried by UAVs,we propose a energy cost of all UAVs based problem to determine how many tasks should be offloaded to high-altitude balloons(HABs) for computing,where UAV-HAB association,the trajectory of UAV,and calculation task splitting are jointly ***,the formulated problem has nonconvex ***,an efficient iterative algorithm by applying successive convex approximation and the block coordinate descent methods is put ***,in each iteration,the UAV-HAB association,calculation task splitting,and UAV trajectory are alternately ***,for the nonconvex UAV trajectory optimization problem,an approximate convex optimization problem is *** numerical results indicate that the scheme of this paper proposed is guaranteed to converge and also significantly reduces the entire power consumption of all UAVs compared to the benchmark schemes.

关键词： Energy consumption Multi-access edge computing Costs Power demand Autonomous aerial vehicles Iterative algorithms Convex functions

Effect of Subcostal Anterior Quadratus Lumborum Block *** Subcostal Transversus Abdominis Plane Block after Laparoscopic Radical Gastrectomy

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Current Medical Science 2021年第5期41卷 974-980页

作者： Bing-qing NIE ling-xia NIU En YANG Shang-long YAO Lei YANG Department of Anesthesiology Union Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

Objective:To evaluate the analgesic effect of ultrasound-guided subcostal anterior quadratus lumborum block(QLB)for laparoscopic radical gastrectomy ***:Patients(aged 20-65 years,ASA Ⅰ-Ⅱ,and weighing 40-75 kg)scheduled for elective laparoscopic radical gastrectomy were enrolled in the current *** patients were randomly assigned to two groups by computer-generated randomization codes:an ultrasound-guided oblique subcostal transversus abdominis plane block(TAPB)group(group T,n=30)or an ultrasound-guided subcostal anterior QLB group(group Q,n=30).In both groups,bilateral ultrasound-guided oblique subcostal TAPB and subcostal anterior QLB were performed before general anesthesia with 0.25% ropivacaine 0.5 mL/*** postoperative management,all patients received patient-controlled intravenous analgesia(PCIA)with nalbuphine and sufentanil after surgery,maintaining visual analogue scale(VAS)scores<4 within 48 *** intraoperative consumption of remifentanil,the requirement for sufentanil as a rescue analgesic,and the VAS scores at rest and coughing were recorded at 1,6,12,24 and 48 h after *** recovery(extubation time after surgery,first ambulation time,first flatus time and length of postoperative hospital stay)and the adverse events(nausea and vomiting,skin pruritus,respiratory depression and nerve-block related complications)were observed and *** primary outcome was the perioperative consumption of ***:Compared with group T,the intraoperative consumption of remifentanil,requirement for sufentanil and the frequency of PCIA were reduced in group ***,VAS scores at all points of observation were significantly lower in group Q than in group *** in group Q were also associated with shorter time to first out-of-bed activity and flatus,and shorter length of postoperative hospital stay than group T(P<0.05).There were no skin pruritus,respiratory depression or nerve-block related complications in both ***

关键词： ultrasound-guided transversus abdominis plane block quadratus lumborum block laparoscopic radical gastrectomy

肠道Prevotella copri在炎症相关疾病中的研究进展

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

赣南医学院学报 2024年第6期44卷 565-570页

作者：陈玲霞谢冰玉宋涛刘志平赣南医科大学基础医学院江西赣州341000

普雷沃氏菌(Prevotella)是短杆状的厌氧性革兰氏阴性菌,属于普氏菌科普雷沃氏菌属。Prevotella在饮食以植物为主的非西方人群中显示出较高的存在率,而Prevotella copri(***)是该菌属中丰度最高的细菌。***可以直接或间接驱动炎症反应,... 详细信息

普雷沃氏菌(Prevotella)是短杆状的厌氧性革兰氏阴性菌,属于普氏菌科普雷沃氏菌属。Prevotella在饮食以植物为主的非西方人群中显示出较高的存在率,而Prevotella copri(***)是该菌属中丰度最高的细菌。***可以直接或间接驱动炎症反应,从而促进炎症相关疾病的发生。研究发现,***通过激活TLR4和mTOR通路、产生琥珀酸盐等途径促进炎症性肠病的发生发展;另外,***可以诱导机体产生抗体、刺激Th17和Th1反应、产生琥珀酸盐、介导瓜氨酸化以触发免疫反应,从而促进类风湿性关节炎的发生发展;***可通过影响支链氨基酸的生物合成诱导胰岛素抵抗,可能导致2型糖尿病,相反,动物实验研究表明,***可以通过胆汁酸代谢、FXR通路等途径改善葡萄糖稳态。本文旨在探讨肠道***与人类炎症相关疾病之间的关系,以增进对***功能和特性的理解,并为未来的研究提供参考。

关键词：普雷沃氏菌 Prevotella copri 炎症炎症性肠病类风湿性关节炎糖尿病

维普期刊数据库博看期刊

Hydrothermal Synthesis, Crystal Structure, Magnetic Properties and Network Topology of a Novel Binuclear Co(Ⅱ) Coordination Polymer_∞~1[Co_2(4,4'-bpy)_2(L)_4](bpy = Bipyridine, HL = 2-Fluorbenzoic Acid)

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2015年第6期34卷 953-959页

作者： HU ling-xia ZHANG Bi-Song WU Chang-Sheng HUANG Dong-Wei QIU Jian-Ping College of Pharmaceutics and Material Engineering Jinhua Polytechnic

One novel binuclear Co（Ⅱ） coordination polymer ∞ [Co2（4,4＇-bpy）2（L）4] （1, bpy = bipyridine, HL = 2-fluorbenzoic acid） has been hydrothermally synthesized and structurally characterized by elemental analysis, IR and X-ray single-crystal diffraction. Complex 1 crystallizes in the monoclinic system, space group P21/c with a = 11.163（2）, b = 21.943（4）, c = 9.6381（19） A, β = 113.92（3）°, V= 2158.2（7） A3, Z= 4, Dc = 1.518 g/cm^3, Mr = 493.31, F（000） =1004, R = 0.0303 and wR = 0.0808 for 3614 observed reflections （I〉 2σ（I））. Complex I exhibits a 3D Schlafli symbol （4.62）（4.66.83） topological framework, and the magnetic characterization shows weak antiferromagnetic coupling exchange between two Co ions.

关键词： Co(Ⅱ) complex coordination polymer crystal structure magnetic properties topological framework

骨科大手术相关深静脉血栓风险预测模型的研究进展

在线全文

学校读者我要写书评

暂无评论

海南医学 2024年第7期35卷 1060-1064页

作者：高奉琼马炎陈伟刘晓童冯加义王安素宋凌霞夏同霞遵义医科大学附属医院护理部贵州遵义563000 遵义医科大学护理学院贵州遵义563000 遵义医科大学附属医院神经外科贵州遵义563000 遵义医科大学附属医院骨科贵州遵义563000

深静脉血栓(DVT)在骨科大手术患者中具有高发病率、高致死率的特点,严重影响了患者的预后,增加了患者的经济负担。有效、精确地预测患者发生DVT的风险,及时、准确地为患者采取预防措施,是DVT风险管理的保障。目前,骨科患者常用的DVT风... 详细信息

深静脉血栓(DVT)在骨科大手术患者中具有高发病率、高致死率的特点,严重影响了患者的预后,增加了患者的经济负担。有效、精确地预测患者发生DVT的风险,及时、准确地为患者采取预防措施,是DVT风险管理的保障。目前,骨科患者常用的DVT风险预测模型包括Caprini、Autar、Wells-DVT和RAPT血栓评估模型,对患者DVT的发生有一定的预测作用且各具优缺点。随着大数据时代的到来,人工智能快速发展,基于机器学习算法建立的DVT风险预测模型表现出更好的预测性能,是未来DVT风险预测模型发展的趋势。

关键词：骨科大手术深静脉血栓预测模型危险因素研究进展

维普期刊数据库博看期刊

Mathematical models of canine right and left atria cardiomyocytes

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第6期11卷 402-416页

作者： ling xia Ying-lan GONG Xiu-wei ZHU Yu ZHANG Qi SUN Heng-gui ZHANG Key Laboratory of Biomedical Engineering of Ministry of Education Department of Biomedical Engineering Zhejiang University Hangzhou 310027 China Center of Arrhythmia Diagnosis and Treatment Cardiovascular Institute & Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100037 China Biological Physics Group School of Physics and Astronomy The University of Manchester Manchester M13 9PL UK

The aim of this study is to build two mathematical models of canine ionic currents specific to right atria and left *** canine left atria mathematical model was firstly modified from the Ramirez-Nattel-Courtemanche(RNC) model using the recently available experimental data of ionic currents and was further developed based on our own experimental data.A model of right atria was then built by considering the differences between right atria and left *** two developed models well reproduced the experimental data on action potential morphology,the rate dependence,and action potential duration *** are useful for investigating the mechanisms underlying the het-erogeneity of canine regional action potentials and would help the simulation of whole heart excitation propagation and cardiac arrhythmia in the near future.

关键词： Atrial fibrillation Canine atria Mathematical model Action potential duration restitution

Preparation of Molecular Imprinted Copolymer Membrane for Uracil Recognition

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2003年第8期14卷 794-796页

作者： Shao ling xia Hong Ying WANG Hong SUN Yu Kun LIU Shao Kui CAO Material Engineering School of Zhengzhou University Zhengzhou 450052

Uracil molecular imprinted membrane was prepared by phase inversion technique with [P(AN-co-MAA)] copolymer. SEM photograph shows that the resultant membrane has a typical ultrafiltration structure with Water Volume Flux of 3.7?0-5m3/m2穝, and uracil substrate permeation experiment shows that the resultant membrane can bind uracil into its structure, and shows a binding equilibrium.

关键词： Molecular imprinting membrane phase inversion.

The steroid-induced microRNA let-7 regulates developmental growth by targeting cdc7 in the Drosophila body

在线全文

学校读者我要写书评

暂无评论

Insect Science 2021年第6期28卷 1621-1632页

作者： Dan-Yan Huang xiao-ling xia Run Huang Sheng Li Dong-Wei Yuan Su-Ning Liu Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology Institute of Insect Science and Technology&School of Life SciencesSouth China Normal UniversityGuangzhou510631China

In insects,20-hydroxyecdysone(20E)limits systemic growth by triggering developmental *** studies have shown that 20E-induced let-7 exhibits crosstalk with the cell ***,we examined the underlying molecular mechanisms and physiological functions of 20E-induced let-7 in the fat body,an organ for energy storage and nutrient mobilization which plays a critical role in the larval ***,the overexpression of let-7 decreased the body size and led to the reduction of both nucleolus and cell sizes in the larval fat *** contrast,the overexpression of let-7-Sponge increased the nucleolus and cell ***,we found that cdc7,encoding a conserved protein kinase that controls the endocycle,is a target of ***,the mutation of cdc7 in the fat body resulted in growth ***,our findings revealed a novel role of let-7 in the control of endoreduplication-related growth during larval-prepupal transition in Drosophila.

关键词： cdc7 Drosophila fat body growth let-7