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Cytotoxicity of Ti–6Al–4V–5Cu Alloy to MC3T3-E1 Cells

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Acta Metallurgica Sinica(English Letters) 2021年第5期34卷 694-700页

作者： Ji Zhang ling ren Ke Yang Institute of Metal Research Chinese Academy of SciencesShenyang110016China

The aim of this work was to study the cytotoxicity of Ti–6 Al–4 V–5 Cu(TC4–Cu)alloy for dental applications and evaluate the cell viability of diff erent fabricated TC4–Cu alloys in contact with MC3 T3-E1 cells in ***–6 Al–4 V(TC4)alloy was used as a negative control to evaluate the cytotoxicity level of TC4–Cu alloy so as to provide basic support for the dental clinical *** group TC4 and experimental group TC4–Cu with diff erent fabrications were incubated in the cell culture *** absorbance value of mouse osteoblast MC3 T3-E1 cells was detected by CCK-8 assay after 1,3 and 7 days,*** relative proliferation rate of cells was calculated,and then the toxicity level was valued for each *** morphology on the surface was also studied by observing the cytoskeleton through F-actin filament *** experimental results showed that the absorbance values for the experimental and the negative control groups were not same at diff erent time *** with diff erent fabricated TC4–Cu alloys,the annealing-TC4–Cu alloy showed much better *** mouse osteoblast MC3 T3-E1 cells cultured with annealing-TC4–Cu,rolling-TC4–Cu and solution+aging-TC4–Cu have no toxic eff ects,and these alloys could promote the proliferation of mouse osteoblasts.

关键词： Cytotoxicity Ti–6Al–4V–5Cu alloy Fabrication Biocompatibility

Continuous Method Development and Numerical Study of HHV Water Gas Production by Pulverized Coal

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Journal of Thermal Science 2011年第5期20卷 474-480页

作者： ren ling Xia Dehong Zhang Yan Department of Thermal Science and Energy Engineering School of Mechanical Engineering University of Science andTechnology Beijing China

In energy industries, it is always of difficulty to produce high heat value（HHV） gas continuously using pulverized coal. In this paper, a new type furnace for partitioned alternative gasification using pulverized coal is developed, in which the oxidation and reduction reaction occur alternatively with the dropping of pulverized coal and finally HHV gas could be continuously obtained at the reduction zone exit and low heat value（LHV） gas at the oxidation zone exit. Furthermore, the gasification characteristics and their factors in furnace are numerically simulated under two dimensional model with a self-coded program, based on heat, mass and energy transfer as well as reaction principles. It is found that the producing rate of HHV gas is 1.10Nm3/kg with heat value of ll.72MJ/Nm3, how- ever, that of LHV gas is 2.58Nm3/kg with heat value of 5.30MJ/Nm3, and the coal gas efficiency is 81.16% under optimized conditions.

关键词： pulverized coal gasification continuous method high heat value water gas

A Comparative Study on the Separating Methods of Al,Ca and Mg Based on Theoretical Energy Consumption

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Journal of Thermal Science 2011年第1期20卷 82-87页

作者： Dehong XIA Yingchun SHANG ling ren Department of Thermal Engineering University of Science and Technology Beijing Beijing 100083

Based on thermodynamics and physical chemistry theory,the theoretical energy consumption (TEC) of the typical separating processes of Al,Ca and Mg has been calculated and *** paper attempts to prove that the thermal method is more reasonable than the electrolytic methods to separate Al,Ca and Mg under the domestic circumstances of the low efficiency of coal-firing power plant at present.

关键词： Aluminum Calcium Magnesium Theoretical energy consumption

Bio-Functional Cu Containing Biomaterials: a New Way to Enhance Bio-Adaption of Biomaterials

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Journal of Materials Science & Technology 2016年第9期32卷 835-839页

作者： Shujing Jin ling ren Ke Yang School of Materials Science and Engineering Dalian University of Technology Institute of Metal Research Chinese Academy of Science

Although being an essential trace element required for human body health, Cu has long been seriously considered toxic when its amount exceeds certain limitation, which significantly limited the wide ap- plication of Cu in biomaterials. However, more and more bio-functions and benefits of Cu were found and confirmed, attracting the attention from biomaterials researchers in recent years. People have tried to immobilize Cu into biomaterials by various ways, in order to develop novel bio-functional Cu containing biomaterials with better bio-adaptions, and several different bio-functions of them have been demonstrated. This paper makes a review of the development of novel bio-functional Cu containing biomaterials, and focuses on their unique roles in enhancing bio-adaption of biomedical materials, including antibacterial performance, stimulating angiogenesis, promoting osteogenesis and inhibition of in-stent restenosis, aiming at proposing a prospective development direction for biomedical materials with better bio-adaptions.

关键词： Biomaterials Cu Antibacterial Angiogenesis Osteogenesis In-stent restenosis

Study of the Reconstruction of Fractal Structure of Closed-cell Aluminum Foam and its Thermal Conductivity

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Journal of Thermal Science 2012年第1期21卷 77-81页

作者： Dehong Xia Shanshan Guo ling ren Department of Thermal Engineering University of Science and Technology Beijing Beijing 100083 China

Based on the characteristics of the internal structure of closed-cell aluminum foam, this paper attempts to illus- trate the process of reconstructing the internal structures of closed-cell aluminum foam in Monte-Carlo method and the fractal characteristics of the reconstructed model. Furthermore, Binary Array Method is proposed by analyzing the reconstructed model and the thermal conductivity model of closed-cell aluminum foam is established. At the same time, the thermal conductivity of the foam materials with different porosity is calculated by Binary Array Method, and the calculated value coincides with the experimental results in the reference, which proves the correctness of these methods.

关键词： fractal closed-cell aluminum foam reconstruction Binary Array Method thermal conductivity

A Better Zn-Ion Storage Device:Recent Progress for Zn-Ion Hybrid Supercapacitors

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Nano-Micro Letters 2022年第4期14卷 158-206页

作者： Jialun Jin Xiangshun Geng Qiang Chen Tian-ling ren School of Integrated Circuits and Beijing National Research Center for Information Science and Technology(BNRist) Tsinghua UniversityBeijing 100084People’s Republic of China College of Material Science and Engineering Zhejiang University of TechnologyHangzhou 310014People’s Republic of China

As a new generation of Zn-ion storage systems,Zn-ion hybrid supercapacitors(ZHSCs)garner tremendous interests recently from researchers due to the perfect integration of batteries and *** have excellent integration of high energy density and power density,which seamlessly bridges the gap between batteries and supercapacitors,becoming one of the most viable future options for large-scale equipment and portable electronic ***,the currently reported two configurations of ZHSCs and corresponding energy storage mechanisms still lack systematic ***,this review will be prudently organized from the perspectives of design strategies,electrode configurations,energy storage mechanisms,recent advances in electrode materials,electrolyte behaviors and further applications(micro or flexible devices)of *** synthesis processes and electrochemical properties of well-designed Zn anodes,capacitor-type electrodes and novel Zn-ion battery-type cathodes are comprehensively ***,a brief summary and outlook for the further development of ZHSCs are presented as *** review will provide timely access for researchers to the recent works regarding ZHSCs.

关键词： Zn-ion storage systems Zn-ion hybrid supercapacitors Carbon electrodes Zinc anodes Electrolytes

Antibacterial copper-bearing titanium alloy prepared by laser powder b e d fusion for superior mechanical performance

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Journal of Materials Science & Technology 2023年第1期132卷 100-109页

作者： Huan Liu Hai Wang ling ren Dong Qiu Ke Yang School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Centre for Additive Manufacturing School of EngineeringRMIT UniversityMelbourneVictoriaAustralia Binzhou Institute of Technology Weiqiao-UCAS Science and Technology ParkBinzhouShandong Province256606China Shandong Key Laboratory of Advanced Aluminium Materials and Technology Weiqiao-UCAS Science and Technology ParkBinzhouShandong Province256606China

Copper element was added in pure titanium to produce a new biomedical titanium-copper alloy by laser powder bed fusion(LPBF).Addition of copper can eliminate the mismatch of high strength but poor duc-tility problem caused by lathα’martensite,which is the usual microstructure of nearαtitanium alloy fabricated by *** of by the usual trade-offrelationship between strength and ductility,which is a long-standing challenge for martensitic titanium alloys,in this study,we proposed a boundary engineer-ing strategy and aim to synergistically enhance the strength and ductility of martensitic titanium alloy fabricated by *** is hypothesized that whilst both low-angle and high-angle grain boundaries are beneficial to the strength,high-angle grain boundary can simultaneously improve the ductility of *** test this strategy,a Ti-5Cu(wt.%)alloy is selected to compare against pure titanium and Ti-6Al-4V at the same laser processing ***,TEM and XRD analysis show that the as-fabricated LPBF Ti-5Cu alloy is comprised of partially tempered martensite with extraordinarily high number density of both high-angle and low-angle grain boundaries as well as low dislocation *** microstructure enables a high tensile strength of 940-1020 MPa,which is at a similar level as LPBF Ti-6Al-4V,and an excellent elongation of 13%-16%,twice as much as that of LPBF *** mechanism of microstruc-ture refinement in LPBF Ti-5Cu at different levels from prior-βgrains,martensitic packets,blocks to laths is also discussed.

关键词： Titanium alloy Laser powder bed fusion Boundary engineering Martensite Mechanical properties

Biocompatibility and Cu ions release kinetics of copper-bearing titanium alloys

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Journal of Materials Science & Technology 2021年第36期95卷 237-248页

作者： ling ren Xiaohe Xu Hui Liu Ke Yang Xun Qi Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of Sciences72 Wenhua RoadShenyang 110016China Department of Ophthalmology Shengjing Hospital of China Medical University36 Sanhao StreetShenyang 110001China School of Materials Science and Engineering University of Science and Technology of China96 Jinzhai RoadHefei 230026China Key Laboratory of Diagnostic Imaging and Interventional Radiology of Liaoning Province Department of RadiologyThe First Affiliated Hospital of China Medical University155 Nanjing Bei StreetShenyang 110001China

To reduce the risk of implant-associated infections,we previously designed and developed a series of medical copper(Cu)-bearing titanium alloys that release Cu ions and hence play an antibacterial ***,both excessive and deficient Cu levels adversely affect human health;therefore,the aim of the present study was to comprehensively evaluate the short-and long-term biosafety of Cu-bearing titanium alloys(Ti6 Al4V-Cu and Ti-Cu)both in vitro and in ***,the predominant kinetic mechanism of Cu ions release and its effect on biosafety were also *** results indicate that the biocompatibility of the Cu-bearing titanium alloys meets the requirements of ISO standards and the Cu ion release kinetics display a good correlation over the entire time period in the normal zero-order model with an almost constant release *** release rate maintained at a parts per billion level safe for humans;consequently,we can conclude that our Cu-bearing titanium alloys have satisfactory biocompatibility.

关键词： Cu ions Kinetic Biocompatibility Titanium

Recent progress in single crystal perovskite X-ray detectors

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Science China(Information Sciences) 2024年第3期67卷 5-19页

作者： Xiao LIU Jun ren Yu-Ang CHEN Xiangshun GENG Dan XIE Tian-ling ren Beijing National Research Center for Information Science and Technology (BNRist) School of Integrated CircuitsTsinghua University

Perovskites have attracted extensive attention as radiation detection material due to their long carrier diffusion length and lifetime, high absorption coefficient, and flexible manufacturing process. Compared with polycrystalline structures, single crystal perovskites improve the performance of optoelectronic devices due to their low defect state density, better photoelectric characteristics, and chemical ***, we review the recent progress of single crystal perovskite X-ray detectors. First, we briefly introduced the basic concepts, detection mechanisms, figure of merits of perovskite X-ray detectors, and the preparation methods of single crystal perovskites. Then, we summarized the significant advancements in single crystal perovskite X-ray detectors in recent times. Finally, we discussed the critical challenges and some practicable solutions for developing high-performance X-ray detectors.

关键词： single crystal perovskites carrier transport radiation detection X-ray detectors X-ray imaging

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