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Effect and mechanism of persimmon leaf flavonoid treatment of experimental oral ulcer

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中国药理学与毒理学杂志 2017年第5期31卷 486-486页

作者： WANG Shuo ZHANG Yong-li HAO mai-ling School of Stomatology of Taishan Medical University

OBJECTIVE To explore the therapeutic effect and its mechanism of persimmon leaf flavonoids(PLF) on rats with oral ulcer. METHODS The oral ulcer model was induced by acetic acid,was used for intervention of Guilin watermelon frost and different dose(20,40 and 80 mg·kg^(-1)) of *** area was calculated on the fourth and the seventh day after injury; the changes of superoxide dismutase(SOD) and malondialdehyde(MDA) in serum and ulcer tissues were observed; the level of tumor necrosis factor alpha(TNF-alpha) in ulcer tissue was measured. To observe the pathological morphological changes of H-E staining. RESULTS Guilin watermelon frost and PLF(40 and 80 mg·kg^(-1))can reduce the ulcer area(P<0.05); PLF(20,40 and 80 mg·kg^(-1)) can increase the activity of SOD and decrease the content of MDA in serum and ulcer tissue(P<0.05); Guilin watermelon frost and PLF could significantly decrease the levels of TNF-alpha in ulcer tissue(P<0.05),and improve the inflammatory infiltration of ulcer tissue. CONCLUSION PLF has certain therapeutic effects on oral ulcer induced by acetic acid,and the mechanism may be related to improve oxidative damage and reduce inflammatory reaction.

关键词： persimmon leaf flavonoids oral ulcer oxidative stress inflammation

Role of Diabetes Mellitus on Treatment Effects in Drug-susceptible Initial Pulmonary Tuberculosis Patients in China

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Biomedical and Environmental Sciences 2017年第9期30卷 671-675页

作者： MA Yan HUANG mai ling LI Tao DU Jian SHU Wei XIE Shi Heng WANG Hong Hong ZHU Guo Feng TAN Shou Yong FU Yan Yong MA Li Ping ZHANG Lian Ying LIU Fei Ying HU Dai Yu ZHANG Yan ling LI Xiang Qun LIU Yu Hong LI Liang Beijing Chest Hospital Capital Medical UniversityBeijing 101149China Beijing Tuberculosis and Thoracic Tumor Research Institute Beijing 101149China Administration Office Clinical Center on Tuberculosis ControlChinese Center for Disease Control and PreventionBeijing 101149China National Center for Tuberculosis Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China Shanghai Municipal Center for Disease Control and Prevention Shanghai 200336China Guangzhou Chest Hospital Guangzhou 510095GuangdongChina Tianjin Centers for Disease Control and Prevention Tianjin 300041China Department of TB Control Henan Center for Disease Control and PreventionZhengzhou 450016HenanChina Hebei Center for Disease Control and Prevention Shijiazhuang 050021HebeiChina Department of TB Control Guangxi Center for Disease Control and PreventionNanning 530021GuangxiChina Chongqing Anti-tuberculosis Institute Chongqing 400050China Yunnan Center for Disease Control and Prevention Kunming 650022YunnanChina

We assessed the role of diabetes mellitus（DM） on treatment effects in drug‐susceptible initial pulmonary tuberculosis（PTB） patients. A prospective study was conducted in eight provinces of China from October 2008 to December 2010. We enrolled 1,313 confirmed drug‐susceptible initial PTB patients, and all subjects received the treatment regimen（2 H3 R3 E3 Z3/4 H3 R3） as recommended by the national guidelines. Of the 1,313 PTB patients, 157（11.9%） had DM; these patients had more sputum smear‐positive rates at the end of the second month [adjusted odds ratios（aO R） 2.829, 95% confidence intervals（CI） 1.783‐4.490], and higher treatment failure（aO R 2.120, 95% CI 1.565‐3.477） and death rates（aO R 1.536, 95% CI 1.011‐2.628）. DM was a contributing factor for culture‐positive rates at the end of the second month and treatment failure and death of PTB patients, thus playing an unfavorable role in treatment effects of PTB.

关键词： Tuberculosis Diabetes mellitus Treatment outcome

A retrospective analysis of RetroNectin-activated cytokine-induced killer cells therapy in the treatment of advanced hepatocelluar carcinoma

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A retrospective analysis of RetroNectin-activated cytokine-i...

第八届中国肿瘤学术大会暨第十三届海峡两岸肿瘤学术会议

作者： wei li huiying zhang lingdi zhao ling mai linping xu yaomei wang quanli gao Department of Immunotherapy the Affiliated Cancer Hospital of Zhengzhou University Henan Cancer Hospital School of Life Sciences Zhengzhou University

＜正＞Objective This retrospective study aims to explore the efficacy of RetroNectin-activated cytokine-induced killer cell（R-CIK）therapy in advanced hepatocellular carcinoma patients,which has not yet been thorough...

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辨析唐代的屯田与营田

中国农史 2008年第1期27卷 41-50页

作者：翟麦玲谢丽华南农业大学人文学院广东广州510642

屯田与营田在唐代是两个既相联系又有区别的概念。二者在经营人员、设置目的、设置地点、经营方式、以及转化为民田等方面,具有相似性;而在组织管理系统方面则是不同的。长期以来,二者之所以常被混淆,一方面是由于二者有不少相似之处,... 详细信息

屯田与营田在唐代是两个既相联系又有区别的概念。二者在经营人员、设置目的、设置地点、经营方式、以及转化为民田等方面,具有相似性;而在组织管理系统方面则是不同的。长期以来,二者之所以常被混淆,一方面是由于二者有不少相似之处,营田使职责也具有双面性;另一方面,史书记载有些地方比较模糊,而且自宋代起人们对二者已经不甚加区分了。本文通过分析历史文献以及敦煌文书中有关屯田与营田的材料,辨析唐代屯田与营田的异同,对未引起研究界重视的二者的区别以及容易混淆的原因,逐一进行辨析。

关键词：唐代屯田营田

Effects of Lead on Systolic and Diastolic Cardiac Functions

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Biomedical and Environmental Sciences 1995年第4期8卷 281-288页

作者： ZOU HE-JIAN DING YUE HUANG KAI-LIAN XU mai-ling TANG GUI-FEN WU MIN-HUA ANO WANG SHOU-YI(Department of Occupational Medicine and Department ofEchocardiography, Hua Shan Hospital, Shanghai MedicalUniversity, Shanghai 200040, China) Department of Occupational Medicine Hua Shan Hospital Shanghai Medical University China.

In this paper, both systolic and diastolic cardiac functions were cvaluatcd in 54 lead exposed and 24 non-exposed workers by Doppler cchocardiography. With regard to systolic cardiac function, the results suggested that cardiac systolic function increased in exposed groups as a compensatory response for the effecl of lead on myocardium. To study left ventriculaf diastolic function, 2.5 MHz pulsed Doppler analyses of transmitral flow velocity were performed from apical four-chamber view. The results showed that timerelated parameters were comparable among all groups, but blood flow velocity through the mitral valve and Doppler area fractions changed significantly in lead-exposed groups as cvidenced by increased value A, decreased value E and E/A ratio. The decrease of diastolic cardiac function was more significant in lead intoxication group. It was also observed in this study that the activity in serum of thc MB isoenzyme of creatine phosphokinase (CPK-MB), one of the indices of myocardial damage, was significantly highcr in exposed group than that in control (P (0.05), and a positive correlation was found between CPK-MB activity and Pb-B. It denoted that the inereasing of lead burden leads to more release of CPK-MB from the myocardial cells and suggested the existence of slight myocardial damage, which, conceivably, might cause harm to diastolic cardiac function

关键词： CPK MB Effects of Lead on Systolic and Diastolic Cardiac Functions

21世纪以来世界民族主义研究的发展——王联教授访谈

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国际政治研究 2021年第2期42卷 134-160页

作者：王联杨钪森买玲北京大学·国际关系学院

一、现代民族主义的概念杨钪森(以下简称"杨"):民族主义是一个相当复杂的概念,请问您如何从理论上界定"民族主义"的概念及其研究范畴?王联(以下简称"王"):很高兴能够有机会在《国际政治研究》的平台上分享我对世界民族主义研究的认识。... 详细信息

一、现代民族主义的概念杨钪森(以下简称"杨"):民族主义是一个相当复杂的概念,请问您如何从理论上界定"民族主义"的概念及其研究范畴?王联(以下简称"王"):很高兴能够有机会在《国际政治研究》的平台上分享我对世界民族主义研究的认识。民族主义是一个非常庞大复杂的研究对象,实际上并没有非常明确的定义,正如英国社会人类学家厄内斯特·盖尔纳(Ernest Gellner)所说:"民族主义是只大象.

关键词：国际政治研究民族主义社会人类学家研究范畴厄内斯特盖尔纳教授访谈

含有格点势的一维Fibonacci链热传导性质的研究

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物理学报 2010年第10期59卷 7266-7270页

作者：徐慧崔麦玲马松山中南大学物理科学与技术学院长沙410083

用传输矩阵的方法,研究了格点势(on-site势)对一维Fibonacci链的热传导性质(透射系数、Lyapunov指数及热导率κ)的影响.研究结果表明:当固定原子质量比和力作用常数比时,随着格点势的增大,低频区域的透射系数减小,对应的Lyapunov指数增... 详细信息

用传输矩阵的方法,研究了格点势(on-site势)对一维Fibonacci链的热传导性质(透射系数、Lyapunov指数及热导率κ)的影响.研究结果表明:当固定原子质量比和力作用常数比时,随着格点势的增大,低频区域的透射系数减小,对应的Lyapunov指数增大,透射谱向高频方向移动.同时,格点势越大,同样大小的体系对应的κ越小,当格点势足够大时,κ会趋近零.在热导率κ对振动频率ω2作图中,κ呈现台阶式缓慢上升的趋势,且在高频端趋于某一稳定值。

关键词： on-site势 Fibonacci链传输矩阵透射系数

原子质量比对一维Fibonacci链热传导性质的影响

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中南大学学报（自然科学版） 2011年第8期42卷 2351-2355页

作者：徐慧崔麦玲马松山中南大学物理科学与技术学院湖南长沙410083

用传输矩阵的方法,研究一维Fibonacci链中2种不同原子的原子质量比对其热传导性能(透射系数及热导率)的影响。研究结果表明:随着原子质量比的增大,高频区域的透射系数减小,透射谱向低频方向移动;同时,原子质量比越大,同样大小的体系对... 详细信息

用传输矩阵的方法,研究一维Fibonacci链中2种不同原子的原子质量比对其热传导性能(透射系数及热导率)的影响。研究结果表明:随着原子质量比的增大,高频区域的透射系数减小,透射谱向低频方向移动;同时,原子质量比越大,同样大小的体系对应的热导率越小,当原子质量比足够大时,热导率会趋近0 W/(m.K)。在热导率与频率平方的关系曲线中,热导率随频率平方呈现台阶式缓慢上升的趋势,且在高频端趋于某一稳定值。

关键词：传输矩阵透射系数振动局域态热传导

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准一维多链无序体系跳跃电导特性

物理学报 2010年第7期59卷 4972-4979页

作者：马松山徐慧郭锐崔麦玲中南大学物理科学与技术学院长沙410083

在单电子紧束缚近似下,建立了准一维多链无序体系直流、交流电子跳跃输运模型,通过计算探讨了无序模式、维度效应、温度及外场对其直流、交流电导率的影响.计算结果表明:准一维多链无序体系的直流、交流电导率随着格点能量无序度的增大... 详细信息

在单电子紧束缚近似下,建立了准一维多链无序体系直流、交流电子跳跃输运模型,通过计算探讨了无序模式、维度效应、温度及外场对其直流、交流电导率的影响.计算结果表明:准一维多链无序体系的直流、交流电导率随着格点能量无序度的增大而减小,非对角无序具有增强体系电子输运能力的作用.随着链数的增加,体系的直流、交流电导率增大,但格点能量无序度较小时,维度效应的影响不明显.在对角无序情况下准一维多链无序体系的交流电导率随温度的升高而增大,而在非对角无序模式下却随温度的升高而减小,但对于直流情况,体系的直流电导率随温度的升高而增大.在外加电场的调制下,体系的直流电导率在强场区随电场强度增加而增大得很快,呈现出非欧姆定律特性,但链数越多,体系的直流电导率随外场强度的增加而增大得越平缓.当外加交变电场时,准一维多链无序体系的交流电导率随外场频率的增大而增大,并满足σac(ω)∝ω2[ln(1/ω)]2的关系式.

关键词：准一维多链无序体系跳跃电导对角无序非对角无序