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Return to work in young and middle-aged colorectal cancer survivors:Factors influencing self-efficacy,fear,resilience,and financial toxicity

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World Journal of Gastroenterology 2025年第1期31卷 79-92页

作者： Dan Hu Yue Li Hua Zhang Lian-Lian Wang Wen-Wen Liu Xin Yang Ming-Zhao Xiao hao-ling Zhang Juan Li Department of Nursing The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Nursing National Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Biomedical Science Advanced Medical and Dental InstituteUniversity Sains MalaysiaPenang 13200Malaysia Academic Affairs Office The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social ***,these survivors encounter significant challenges during their RTW ***,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC *** To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW *** A cross-sectional investigation was adopted in this *** September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in *** investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and *** analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were *** A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 *** regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further *** levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC *** professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.

关键词： Return to work Colorectal neoplasms Return-to-work self-efficacy Fear of progression Family resilience Financial toxicity

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Numerical simulation on flow of ice slurry in horizontal straight tube

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Frontiers in Energy 2021年第1期15卷 201-207页

作者： Shengchun LIU Ming SONG ling hao Pengxiao WANG Tianjin Key Laboratory of Refrigeration Technology Tianjin University of CommerceTianjin 300134China

Numerical simulation on flow of ice slurry in horizontal straight tubes was conducted in this paper to improve its transportation characteristics and *** paper determined the influence of the diameter and length of tubes,the ice packing factors(IPF)and the flow velocity of ice slurry on pressure loss by using numerical simulation,based on two-phase flow and the granular dynamic ***,it was found that the deviation between the simulation results and experimental data could be reduced from 20%to 5%by adjusting the viscosity which was reflected by *** confirmed the reliability of the simulation ***,two mathematical correlations between viscosity and flow velocity were developed *** could also be concluded that future rheological model of ice slurry should be considered in three sections clarified by the flow velocity,which determined the fundamental difference from single-phase fluid.

关键词： ice slurry horizontal tubes numerical simulation pressure drop viscosity model

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Spermatocytic tumor:A rare case report

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World Journal of Clinical Cases 2021年第35期9卷 11115-11121页

作者： Mei-ling hao Chun-Hui Li Department of Pathology Chengde Medical College Affiliated HospitalChengde 067000Hebei ProvinceChina

BACKGROUND Spermatocytic tumor is a rare,malignant neoplasm of the *** the prognosis for this tumor type is favorable,accurate diagnosis and differentiation from other malignant testicular neoplasms(classic seminoma and lymphoma)are *** add to the existing literature on the diagnosis of spermatocytic tumor,herein we report the detailed clinical and histopathologic findings for a case that we *** SUMMARY A 60-year-old Chinese man presented with a solid mass in the right *** mass was surgically removed and spermatocytic tumor was *** microscopy,the tumor cells displayed an unusual arrangement in lobules,presenting a pseudo-glandular *** summarize and compare the diagnostic features of this tumor and those of the differential diagnoses,we report our case findings and those mentioned in the literature for various testicular *** imaging methods can detect masses early in development,their diagnostic capabilities are ***,histopathology,and immunohistochemistry are necessary for confirmatory *** It is important to identify and review the key diagnostic features of spermatocytic tumor.

关键词： Spermatocytic tumor Germ cell tumor Immunohistochemistry Pseudoglandular Case report

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A simple and controllable nanostructure comprising non-conductive poly（vinylidene fluoride） and graphene nanosheets for supercapacitor

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Frontiers of Materials Science 2012年第2期6卷 149-159页

作者： Jing SUN ling-hao HE Qiao-ling Zhao Li-Fang CAI Rui SONG Yong-Mei hao Zhi MA WeiHUANG Key Lab of Surface and Interface Sciences of Henan Provincial Zhengzhou University of Light IndustryZhengzhou 450002China Shanghai Institute of Organic Chemistry Chinese Academy of SciencesShanghai 200032china College of Chemistry and Chemical Engineering Gracluate University of Chinese Academy of SciencesBeijing 100049China Laboratory of Advanced Polymer Materials Institute of Chemistry Chinese Academy of SciencesBeijing 100080China

An effective method was used to Ioidal suspensions of highly reduced graphene produce stable and homogeneous coloxide （RGO） in N,N-dimethylformamide （DMF） without the assistance of dispersing agents. According to the results of general characterization, relatively pure graphene sheets with the morphology of single layer or few-layer structure were obtained. Then nanocomposite powders of RGO and poly （vinylidene fluoride）（PVDF） were prepared by vacuum filtration of the mixed dispersions of both components. The nanocomposites exhibit a high-frequency capacitative response with small equivalent series resistance （ESR） at 0.4Q, a nearly rectangular cyclic voltammogram and possess a rapid current response as electrodes for supercapacitor in 5mol/L KOH electrolyte. Furthermore, after 600 galvanostatic charge/ discharge cycles, the supercapacitor still performs a very high stability and efficiency of capacitance.

关键词： reduced graphene oxide (RGO) poly(vinylidene fluoride) (PVDF) nano.,composite supercapacitor

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Modification on crystallization of poly（vinylidene fluoride）（PVDF） by solvent extraction of poly（methyl methacrylate）（PMMA） in PVDF/PMMA blends

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Frontiers of Materials Science 2011年第4期5卷 388-400页

作者： Jing SUN Lu YAO Qiao-ling Zhao Jin HUANG Rui SONG Zhi MA ling-hao HE Wei HUANG Yong-Mei hao Key Laboratory of Surface and Interface Sciences of Henan Province Zhengzhou University of Light Industry Zhengzhou 450005 China Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China College of Chemistry and Chemical Engineering Graduate University of Chinese Academy of Sciences Beijing 100049 China Laboratory of Advanced Polymer Materials Institute of Chemistry Chinese Academy of Sciences Beijing 100080 China

The crystallization modification of poly（vinylidene fluoride）（PVDF） was investigated for the blend films of PVDF and poiy（methyl methacrylate）（PMMA）. The mass crystallinity （Xc） and further, the β-phase content （F（β）） of PVDF, were studied for the asprepared blend films with different mass ratios. In addition, the variations of Xc and F（β） were systematically probed once the PMMA component was removed from the related blend systems. DSC, FTIR and XRD measurements all indicated that 1）Xc, F（β） and even the content of a-phase （F（a）） decreased with the addition of PMMA; 2） with the extraction of PMMA, both Xc and F（β） increased while F（a） decreased. It is worth noting that the increase of Xc and F（β） depended on the relative amount of extracted PMMA （EpMMA）, i.e., the more PMMA was removed, the more Xc and F（β） increased. These results reveal the hindrance effect from the PMMA constituent to the crystallization of PVDF, and consequently, this restriction would be released when the PMMA was extracted.

关键词： poly(vinylidene fluoride) poly(methyl methacrylate) blend film crystallization

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A dynamic control structure of liquid-only transfer stream distillation column

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Chinese Journal of Chemical Engineering 2023年第7期59卷 135-145页

作者： Borui Liu Tao Zhang Yi Zheng Kailong Li Hui Pan hao ling State Key Laboratory of Chemical Engineering School of Chemical EngineeringEast China University of Science and TechnologyShanghai 200237China Shanghai Key Laboratory of Materials Protection and Advanced Materials in Electric Power College of Environmental and Chemical EngineeringShanghai University of Electric PowerShanghai 200090China

The intention of this fundamental work is to explore the manipulation of a mixture of benzene,toluene and o-xylene separated from liquid-only transfer divided-wall column(LTS-DWC).First,two control structures are clearly proposed,including seven component control loops(CS1)and seven temperature control loops(CS2).However,two control structures can handle ±10% feed disturbances rather than larger feed ***,an equivalent four-column model by introducing withdraw ratio is developed to discuss the effect of two liquid-only side-stream on the overall reboiler *** is indicated that the second liquid-only side-stream withdraw ratio strongly affects the overall energy ***,six-component control loops within the fixed second liquid-only side-stream withdraw ratio(CS3)is proposed and the purity of products returns to set value even as facing ±20% feed ***,based on the above results,it is established a temperature control structure(CS4)for controlling fixed second liquid-only side-stream withdraw ratio,which can cope with ±15% *** by these findings,an insight into the dynamic control of LTS-DWC promotes the industrial implementation of DWC through new liquid-only side-stream configurations.

关键词： Separation Divided-wall column Liquid-only transfer stream Optimal design Dynamic modeling

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Concise synthesis of valuable chiral N-Boc-β-benzyl-β-amino acid via construction of chiral N-Boc-3-benzyl-5-oxoisoxazolidine through cross-metathesis/conjugate addition/oxidation

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Chinese Chemical Letters 2017年第2期28卷 471-475页

作者： Hong-Tao Jiang hao-ling Gao Cheng-Sheng Ge College of Chemical Engineering Zhejiang University of Technology College of Chemistry and Materials Engineering Quzhou University

Valuable chiral N-Boc-β-benzyl-β-amino acid was concisely synthesized via construction of chiral NBoc-3-benzyl-5-oxoisoxazolidine through cross-metathesis/conjugate addition/*** of the starting materials for the synthesis of chiral N-Boc-β-benzyl-β-amino acid are cheap,and two-step short procedure make it easy for the rapid construction of various chiral β-arylmethyl-β-amino acids and important drugs,such as sitagliptin phosphate.

关键词： Synthetic methods Conjugate addition Organocatalysis Asymmetric catalysis Enantioselective

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Effect of Gubenfangxiao decoction on respiratory syncytial virus-induced asthma and expression of asthma susceptibility gene orosomucoid 1-like protein 3 in mice

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Journal of Traditional Chinese Medicine 2016年第1期36卷 101-106页

作者： Huang Zhengguang Gao Lijuan Zhao Xia ling hao Chen Wenjun Institute of Pediatrics of Nanjing University of Chinese Medicine Jiangsu Key Laboratory of Pediatric Respiratory Disease

OBJECTIVE： To investigate the effect of Gubenfangxiao decoction （GBFXD） on respiratory-syncytial-virus （RSV） -induced asthma and the expression of asthma susceptibility gene, orosomucoid 1-1ike protein 3 （ORMDL3） in mice. METHODS： Seventy-two female BALB/c mice were randomly assigned to normal, model, GBFXD high dose, GBFXD moderate dose, GBFXD low dose and montelukast groups. An asthma model was induced via intraperitoneal injection and aerosol inhalation of ovalbumin （OVA） and repeated intranasal instillation of RSV in all mice, except those in the normal group. All treatments were administered at the first onset of asthma （within 8 weeks of model establishment） and the mice were euthanized after 28 days of treatment. The levels of transforming growth factor-β （TGF-β） and interleukin-6 （IL-6） in bronchoalveolar lavage fluid （BALF） of the mice were measured and the expression of asthma sus- ceptibility gene ORMDL3 in lung tissue was deter- mined using real-time polymerase chain reaction （RT-PCR） and western blotting. RESULTS： Expression of ORMDL3 and levels of TGF-β and IL-6 were significantly higher in the mod- el group （P 〈 0.05, P 〈 0.01） compared with the normal mice. Levels of ORMDL3, TGF-β and IL-6 were significantly lower in all three GBFXD treated groups （P 〈 0.05） compared with the model group. However, the levels in the GBFXD treatment groups did not differ significantly from the montelukast group. CONCLUSION： GBFXD had a therapeutic effect in this experimental model. The functional mechanism of GBFXD may involve multiple factors, including alleviation of airway inflammation, down-regulation of asthma susceptibility gene ORMDL3 and inhibition of airway remodeling.

关键词： Asthma ORMDL3 protein, mouse Air-way remodeling Gubenfangxiao decoction

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Seismic tomography of the crust and upper mantle in the Bohai Bay Basin and its adjacent regions

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Science China Earth Sciences 2007年第12期50卷 1810-1822页

作者： ZHANG ling LIU JinSong hao TianYao LIU JianHua XU Yi Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China Gocad Research Group Rue Doyen M. Roubault 54501 Nancy France Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China

In the Bohai Bay Basin and its adjacent regions(112°―124°E,34°―42°N),there exists abundant gas-petroleum while modern inter-plate seismic activity is *** the tectonic structure of this region is very complicated,plenty of geological,geophysical and geochemical data and results are obtained through previous *** the basis of absorbing previous results,especially various kinds of geological and geophysical results,we collect and process the arrival time of P-wave phases of local events and tele-seismic events recorded by the station within this region from 1978 to 2004,build the responding initial model,and image the velocity structure of the crust and upper mantle of this region via *** perturbation images of various depths and velocity profiles imply that the velocity structure of the crust and upper mantle in the Bohai Bay Basin and its adjacent regions is mainly influenced by the surface tectonic units,and is characterized by "Stripped along east-west,and zoned along south-north";some large-scaled faults penetrate Moho and lithosphere,and provide the channels for the basic lava or hot mass upwelling from the mantle.

关键词： Bohai Bay Basin, tomography, crust and upper mantle

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Rethinking the Rise of Global Central Bank Digital Currencies:A Policy Perspective

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Contemporary Social Sciences 2023年第1期8卷 1-16页

作者： Chen Gengxuan Jia Qinmin ling hao Sichuan Academy of Social Sciences Southwestern University of Finance and Economics The Chinese University of Hong Kong China

This article discusses the impact of central bank digital currency(CBDC)from the perspective of monetary and fiscal *** mainly discuss how retail CBDC can improve traditional policy *** argue that A CBDC helps existing monetary policies to break through the zero lower bound,shorten the policy time lag,realize selective policy interventions,and make possible the price level target policy ***,the combination of CBDC and smart contracts can directly affect the performance of the fiscal *** with the convenience and impact of CDBC as a medium of exchange,its impact as a policy tool is more *** current monetary policy is facing a zero lower *** fiscal policy is facing a huge sovereign debt crisis and the impact of other private digital currencies on fiat money,which makes the importance of CBDC as a new policy tool more ***,the research on CBDC as a policy tool has many fundamental questions that remain to be *** paper contextualizes CBDC with global challenges in policies and new technology advances,and the authors rethink CBDC from a policy perspective,which may provide many new thoughts and have implications for the rise of global CBDC.

关键词： CBDC monetary policy fiscal policy

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