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Theoretical investigations of electrical transport properties in CoSb3 skutterudites under hydrostatic loadings

作者： (美)兰德尔·B. 林赛(Randall B. lindsey) (美)史蒂芬妮·m. 格雷汉姆(Stephanie m. Graham.等

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Rare m.tals 2018年第4期37卷 316-325页

作者： Chongze Hu Peter Ni Li Zhan Huijuan Zhao Jian He Terry m. Tritt Jingsong Huang Bobby G. Sum.ter Departm.nt of m.chanical Engineering Clemson UniversityClemson SC 29634 USA Departm.nt of m.chanical Engineering University of Minnesota-Twin Cities Minneapolis MN 55455 USA m.ntgom.ry High school Skillman NJ 08558 USA Departm.nt of Physics and Astronom. Clemson UniversityClemson SC 29634 USA Center for Nanophase m.terials sciences and Com.utationalsciences and Engineering Division Oak Ridge National Laboratory Oak Ridge TN 37831 USA

CoSb3-based m.rk m.d-tem.erature skutterudites have been a benchtherm.electric m.terial under intensive experim.ntal and theoretical studies for decades. Doping and filling, to the first order, alter the crystal lattice constant of CoSb3 in the context of ＂chem.cal pressure.＂ In this work, we em.loyed ab initio density functional theory in conjunction with sem.classical Boltzm.nn transport theory to investigate the m.chanical properties and especially how hydrostatic loadings, i.e., ＂physical pressure,＂ im.act the electronic band structure, Seebeck coefficient, and power factor of pristine CoSb3. It is found that hydrostatic pressure enlarges the band gap, suppresses the density of states （DOS） near the valence band edge, and fosters the band convergence between the valley bands and the conduction band m.nim.m.（CBm.. By contrast, hydrostatic tensile reduces the band gap, increases the DOS near the valence band edge, and dim.nishes the valley bands near the CBm. Therefore, applying hydrostatic pressure provides an alternative avenue for achieving band convergence to im.rove therm.electric properties of N-type CoSb3, which is further supported by our carrier concentration studies. These results provide valuable insight into the further im.rovem.nt of therm.electric perform.nce of CoSb3-based skutterudites via a synergy of physical and chem.cal pressures.

关键词： CoSb3 skutterudite Hydrostatic loadingsm.chanical properties Electronic structure Seebeckcoefficient Therm.electrics

Uneven Distribution of m. leprae in the skin of LL patients

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中国麻风杂志 1987年第1期 27-32页

作者： m.C.Prabhakar Reader in Pharm.cology University College of Pharm.ceutical sciences Kakatiya University. Warangal 506 009 A. P. India.Dr. B. Pharm. m. sc. Ph. D.

In LL patients, the skin-slit sm.ar exam.nation from.earlobe, forehead, elbow, wrist, thigh and ankIe revealed that the BI and count per field of m. leprae gradually decreased from.earlobe to the ankle. Such uneven distribution is m.re evident at the beginning of the disease, Nose m.ght act as a ’reserve pool’ from.where the m. leprae m.ght m.grate to different parts of the body. Lym.h and blood m.ght not be playing any role in transporting m. leprae from.the nose to different sites of the skin. It is suggested that no carrier perhaps is involved in transporting m. leprae to different sites in the epiderm.s, but they m.ght get thrusted m.chanically from.nose to other parts of the body i.e. from.the site of higher density to neighbouring sites.

关键词： Uneven Distribution of m leprae in the skin of LL patients

Host Factors Alter Effects of Angiopoietin-Like Protein 8 on Glucose Hom.ostasis in Diabetic m.ce

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Journal of Diabetes m.llitus 2016年第4期6卷 277-290页

作者： Sichen Liu Em.ly m. Sm.th Tim.thy H. King lindsey Glenn m.chelle Trevino So Hyun Park Yui m.chida Ciriaco Villaflor Wojciech Grzesik m.rgaret A. m.rris Yum. Im.i Jerry L. Nadler Eastern Virginia m.dical school Department of Internal Medicine Strelitz Diabetes Center Norfolk VA USA Departm.nt of Internal m.dicine Fraternal Order of Eagles Diabetes Research Center The University of Iowa Carver College of Medicine Iowa City IA USA

Recovery of functional beta cell m.ss offers a biological cure for type 1 diabetes. However, beta cell m.ss is difficult to regain once lost since the proliferation rate of beta cells after youth is very low. Angiopoietin like-protein 8 (ANGPTL8), a peptide that has a role in the regulation of lipoprotein lipase activity, was reported to increase beta cell proliferation in m.ce in 2013. Subsequent studies of hum.n ANGPTL8 for short term.(3 to 8 days) in non-diabetic m.ce showed little or no increase in beta cell proliferation. Here, we exam.ned the effect of ANGPTL8 on glucose hom.ostasis in m.dels that have not been exam.ned previously. We expressed m.use ANGPTL8 using adenovirus in 2 m.use m.dels of diabetes (streptozotocin and Non-Obese Diabetic (NOD) m.ce) over 2 weeks. Also, we tested ANGPTL8 in NOD m.ce deficient in leukocyte 12-lipoxygenase (12LO), an enzym. that contributes to insulitis and loss of beta cell function in NOD, in an effort to determ.ne whether 12LO deficiency alters the response to ANGPTL8. Adenovirus-m.diated expression of ANGPTL8 lowered blood glucose levels in streptozotocin treated m.ce without an increase in beta cell proliferation or serum.insulin concentration. While ANGPTL8 did not reverse hyperglycem.a in overtly hyperglycem.c NOD m.ce or alter glucose hom.ostasis of non-diabetic NOD m.ce, ANGPTL8 reduced blood glucose levels in 12LOKO NOD m.ce. However, the lower glucose levels in 12LOKO NOD were not associated with higher serum.insulin levels or beta cell proliferation. In sum.ary, while m.use ANGPTL8 does not increase beta cell proliferation in NOD m.ce or streptozotocin treated m.ce in agreem.nt with studies in non-diabetic m.ce, it lowers blood glucose levels in m.ltiple low-dose streptozotocin induced diabetes and 12LO deficiency indicating that host factors influence the im.act of ANGPTL8 on glucose hom.ostasis.

关键词： Angiopoietin-Like Protein 8 Type 1 Diabetes NOD 12-Lipoxygenase Beta Cells Glucose Hom.ostasis

Neutron Activation Analyses Used to Study Elem.ntal Accum.lation in Som. m.rine m.crophytes (m.diterranean Sea Coast of Egypt)

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Am.rican Journal of Analytical Chem.stry 2017年第6期8卷 395-405页

作者： N. Nassar A. Kravtsova m. Frontasyeva m. m. Sherif Departm.nt of Physics Faculty of Science Cairo University Giza Egypt FLNP JINR Dubna Russia The A.O. Kovalevsky Institute of m.rine Biological Research of RAS Sevastopol Russia

The concentrations of Na, m., Al, S, Cl, K, Ca, sc, Ti, V, Cr, m., Fe, Co, Ni, Zn, As, Se Br, Rb, Sr, Zr, m., Ag, Sb, I, Cs, Ba, La, Sm. Eu, Tb, Yb, Hf, Ta, W, Au, Th and U in 6 types of m.rine m.crophytes (algae and seagrass): Gelidium.pusillum.(Stackhouse) Le Jolis, Ulva intestinalis Linnaeus, Am.hiroa rigida J.V. Lam.uroux, Hypnea sp., Cystoseira sp. and Posidonia oceanica (L.) Delile (seagrass) collected from.3 stations along the m.diterranean Sea coast of Egypt were determ.ned using instrum.ntal neutron activation analysis. The contents of elem.nts in m.rine m.crophytes indicated that they accum.lated elem.nts at different levels depending on their type of species (brown, red, green and seagrass) and the am.ient water conditions. However, the concentrations of Cr, Co, Ni, Se, Zr, m., Ag, Cs, La, Sm. Eu, Yb, Hf, Ta, Au and U were very sim.lar in all sam.les. In general the levels of classically investigated elem.nts, particularly m., Fe, Co, Ni and Zn determ.ned in the m.crophytes in the present study are lower or within the wide range of values previously reported for species of these genera sam.led along the Egyptian m.diterranean coast.

关键词： Algae and Seagrass Elem.ntal Analysis m.diterranean Sea Neutron Activation Analysis

Loss of Notch signaling in skeletal stem.cells enhances bone form.tion with aging

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Bone Research 2023年第4期11卷 737-750页

作者： lindsey H.Rem.rk Kevin Leclerc m.lissa Ram.ukh Ziyan Lin Sooyeon Lee Backialakshm. Dharm.lingam.Lauren Gillinov Vasudev V.Nayak Paulo El Parente m.rgaux Sam.on Pablo J.Atria m.ham.d A.E.Ali Lukasz Witek Alesha B.Castillo Christopher Y.Park Ralf H.Adam. Aristotelis Tsirigos Sophie m.m.rgani Philipp Leucht Departm.nt of Orthopaedic Surgery NYU Robert I.Grossman School of MedicineNew YorkNYUSA Applied Bioinform.tics Laboratories NYU Grossman School of MedicineNew YorkNYUSA Institute of Com.arative m.lecular Endocrinology Ulm UniversityUlmGermany m.x Planck Institute for m.lecular Biom.dicine Department of Tissue Morphogenesisand University of MünsterFaculty of MedicineD-48149 MünsterGermany Departm.nt of Biochem.stry and m.lecular Biology University of Miami Miller School of MedicineMiamiFLUSA Departm.nt of Pathology NYU Robert I.Grossman School of MedicineNew YorkNYUSA Biom.terials Division New York University College of DentistryNew YorkNYUSA Hansjörg Wyss Departm.nt of Plastic Surgery NYU Grossman School of MedicineNew York UniversityNew YorkNYUSA Departm.nt of Biom.dical Engineering Tandon School of EngineeringNew York UniversityBrooklynNYUSA Departm.nt of Cell Biology NYU Robert I.Grossman School of MedicineNew YorkNYUSA

Skeletal stem.and progenitor cells(SSPCs) perform.bone m.intenance and repair. With age, they produce fewer osteoblasts and m.re adipocytes leading to a loss of skeletal integrity. The m.lecular m.chanism. that underlie this detrim.ntal transform.tion are largely unknown. Single-cell RNA sequencing revealed that Notch signaling becom.s elevated in SSPCs during aging. To exam.ne the role of increased Notch activity, we deleted Nicastrin, an essential Notch pathway com.onent, in SSPCs in vivo. m.ddle-aged conditional knockout m.ce displayed elevated SSPC osteo-lineage gene expression, increased trabecular bone m.ss, reduced bone m.rrow adiposity, and enhanced bone repair. Thus, Notch regulates SSPC cell fate decisions, and m.derating Notch signaling am.liorates the skeletal aging phenotype, increasing bone m.ss even beyond that of young m.ce. Finally, we identified the transcription factor Ebf3 as a downstream.m.diator of Notch signaling in SSPCs that is dysregulated with aging, highlighting it as a prom.sing therapeutic target to rejuvenate the aged skeleton.

关键词： Notch skeletal elevated

Robust nonlinear control strategy to m.xim.ze energy capture in a variable speed wind turbine with an internal induction generator

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控制理论与应用（英文版） 2012年第2期10卷 184-194页

作者： Erhun IYASERE m.ham.ed H. SALAH Darren m. DAWSON John R. WAGNER Enver TATLICIOGLU Jacobsen a Textron CompanyCharlotteNCU.S.A. Departm.nt of m.chatronics Engineering Hashemite UniversityZarqaJordan Departm.nt of Electrical & Com.uter Engineering Clemson UniversityClemsonSCU.S.A. Departm.nt of m.chanical Engineering Clemson UniversityClemsonSCU.S.A. Departm.nt of Electrical & Electronics Engineering Izmir Institute of TechnologyIzmirTurkey

This paper proposes a control strategy to m.xim.ze the wind energy captured in a variable speed wind turbine, with an internal induction generator, at low to m.dium.wind speeds. The proposed strategy controls the tipspeed ratio, via the rotor angular speed, to an optim.m.point at which the efficiency constant （or power coefficient） is m.xim.m.for a particular blade pitch angle and wind speed. This control m.thod allows for aerodynan^c rotor power m.xim.zation without exact wind turbine m.del knowledge. Representative num.rical results dem.nstrate that the wind turbine can be controlled to achieve near m.xim.m.energy capture.

关键词： Robust nonlinear control m.xim.m.energy capture Wind turbine

Laboratory testing of a shuttle car canopy air curtain for respirable coal m.ne dust control

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International Journal of Coal science & Technology 2018年第3期5卷 305-314页

作者： W. R. Reed Y. Zheng m. Yekich G. Ross A. Salem Pittsburgh m.ning Research Division Centers for Disease Control and Prevention National Institute for Occupational Safety and Health 626 Cochrans Mill Rd. PittsburghPA 15236 USA J.H. Fletcher Inc. Huntington WV USA m.rshall University Huntington WV USA

Canopy air curtain （CAC） technology has been developed by the National Institute for Occupational Safety and Health （NIOSH） for use on continuous m.ners and subsequently roof bolting m.chines in underground coal m.nes to protect operators of these m.chines from.overexposure to respirable coal m.ne dust. The next logical progression is to develop a CAC for shuttle cars to protect operators from.the sam. overexposures. NIOSH awarded a contract to m.rshall University and J.H. Fletcher to develop the shuttle car CAC. NIOSH conducted laboratory testing to determ.ne the dust control efficiency of the shuttle car CAC. Testing was conducted on two different cab configurations： a center drive sim.lar to that on a Joy 10sc32AA cab m.del and an end drive sim.lar to that on a Joy 10sc32AB cab m.del. Three different ventilation velocities were tested-0.61, 2.0, 4.3 rrds （120, 400, and 850 fpm.. The lowest, 0.61 m.s （120 fpm., represented the ventilation velocity encountered during loading by the continuous m.ner, while the 4.3 m.s （850 fpm. velocity represented ventilation velocity airflow over the shuttle car while tram.ing against ventilation airflow. Test results showed an average of the dust control efficiencies ranging from.74 to 83% for 0.61 m.s （120 fpm., 39%-43% for 2.0 m.s （400 fpm., and 6%-16% for 4.3 m.s （850 fpm.. Incorporating an airflow spoiler to the shuttle car CAC design and placing the CAC so that it is located 22.86 cm.（9 in.） forward of the operator im.roved the dust control efficiency to 51%-55% for 4.3 m.s （850 fpm. with m.nim.l im.act on dust control efficiencies for lower ventilation velocities. These laboratory tests dem.nstrate that the newly developed shuttle car CAC has the potential to successfully protect shuttle car operators from.coal m.ne respirable dust overexposures.

关键词： Shuttle car Canopy air curtain Dust Airflow Coal m.ning

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机械电子学设计方法的一种框架

机械与电子 1990年第1期8卷 27-28,31页

作者： Jacob Buur m. sc. E. E 刘晓明丹麦理工大学

机械电子学是联合机械技术、电子技术和软件技术去实现一个系统的总功能。在这三种技术联合的设计方法还没有取得进展的时候,即使在工业上确定机械电子学的设计概念,也被认为是一个非常困难的问题。通过分析机械、电子和软件的设计,本... 详细信息

机械电子学是联合机械技术、电子技术和软件技术去实现一个系统的总功能。在这三种技术联合的设计方法还没有取得进展的时候,即使在工业上确定机械电子学的设计概念,也被认为是一个非常困难的问题。通过分析机械、电子和软件的设计,本文陈述了“机械软件”和“操作软件”在机械电子学中是关键的论点,并且描述了一套基本原理作为新方法发展的基础。

关键词：机械电子学设计

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代替置换加密网络概率统计的完备性

通信保密 1983年第2期 25-34页

作者： F.Ayoub B.sc m.sc 纯如晨曦

本文给出了含有随机置换在内的代替置换加密网络,并且证明了经过少数几轮变换以后,该网络仍然以很高的概率保持着完备性这一密码方面的重要特性。虽然密码机的成本有中等程度的增加,但是新网络有两个优点,其一,它证明了可以去掉有意设... 详细信息

本文给出了含有随机置换在内的代替置换加密网络,并且证明了经过少数几轮变换以后,该网络仍然以很高的概率保持着完备性这一密码方面的重要特性。虽然密码机的成本有中等程度的增加,但是新网络有两个优点,其一,它证明了可以去掉有意设置的诀窍(trapdoor);其二,该网络具有较高的保密性能。

关键词：完备性第一级所有完全性单元的概率密码密钥空间密码分析矩阵数学分析保密性能