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访法国电影导演吕克·贝松(英文)

新东方英语（中英文版） 2006年第10期 50-51页

作者： lindsay

吕克·贝松(LucBesson),1959年3月18日生于法国巴黎,从小就显示出非凡的创造力。他17岁进入电影圈,执导的第一部长故事片《最后决战》(Derniercombat,Le,1983)在1983年阿沃里亚兹电影节上一举获得评委会大奖和评论大奖。1985年,其第二... 详细信息

吕克·贝松(LucBesson),1959年3月18日生于法国巴黎,从小就显示出非凡的创造力。他17岁进入电影圈,执导的第一部长故事片《最后决战》(Derniercombat,Le,1983)在1983年阿沃里亚兹电影节上一举获得评委会大奖和评论大奖。1985年,其第二部作品《地下铁》(Subway)出击。1986年开拍的《碧海蓝天》(TheBigBlue)成为1988年戛纳国际电影节开幕片。1990年的《尼基塔》(Nik.ta)是贝松的又一部全球票房大片。1991年贝松执导了《亚特兰蒂斯》(Atlantis)。在这场没有对白的水下之旅中,海豚、鲸和鲨鱼是惟一的角色。之后,贝松在纽约导演了《这个杀手不太冷》(Leon,1994),这部让·雷诺主演的影片成为1995年全球最叫座的法国片。1997年,贝松携作品回到戛纳《,第五元素》(TheFifthElement)是当年电影节的开幕片。贝松还借由此片摘得恺撒奖最佳导演奖。第八部电影《圣女贞德》(Messenger:TheStoryofJoanArc),贝松转向了一种新的类型:史诗片。1998年,贝松开始以非导演的身份制作影片。他监制的《出租车》(Taxi)系列的第一部大获成功。

关键词：法国国际电影节电影导演戛纳碧海作品执导影片海豚创造力

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母亲节

新东方英语（中学版） 2006年第5期 42-43页

作者： lindsay

今年的5月14日是母亲节,在这一天,我们向妈妈们表达敬意,感谢她们的爱和关怀。你们知道吗?关于这个节日还有一个感人的故事呢!这个故事讲述了一个女儿对妈妈的爱。

关键词：母亲节澳大利亚故事康乃馨表达意大利安娜比利时节日讲述

Acupuncture's Role in Solving the Opioid Epidemic: Evidence, Cost-Effectiveness, and Care Availability for Acupuncture as a Primary, Non-Pharmacologic Method for Pain Relief and Management-White Paper 2017

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Journal of Integrative medicine 2017年第6期15卷 411-425页

作者： arthur yin fan david w.miller bonnie bolash matthew bauer john mcdonald sarah faggert hongjian he yong ming li amy mateck. lindy camardella mel hopper k.ppelman jennifer a.m.stone lindsay meade john pang the american tcm association ViennaVA 22182USA the american society of acupuncturists ChicagoIL 60618USA the joint acupuncture opioid task.force La VerneCA 91750USA pacific college of oriental medicine ChicagoIL 60601USA the acupuncture now foundation CA 91750USA the acupuncture evidence project ProvidenceRI 02860USA the acupuncture society of virginia ViennaVA 22182USA the national federation of chinese tcm organizations New YorkNY 11501USA the american alliance for professional acupuncture safety GreenwichCT 06878USA the american traditional chinese medicine society New YorkNY 11501USA highland hospital alameda health systemOaklandCA 94602USA indiana university school of medicine IndianapolisIN 46202USA university of california san diego school of medicineSan DiegoCA 92093USA

The United States （U.S.） is facing a national opioid epidemic, and medical systems are in need of non- pharmacologic strategies that can be employed to decrease the public＇s opioid dependence. Acupuncture has emerged as a powerful, evidence-based, safe, cost-effective, and available treatment modality suitable to meeting this need. Acupuncture has been shown to be effective for the management of numerous types of pain conditions, and mechanisms of action for acupuncture have been described and are understandable from biomedical, physiologic perspectives. Further, acupuncture＇s cost-effectiveness can dramatically decrease health care expenditures, both from the standpoint of treating acute pain and through avoiding addiction to opioids that requires costly care, destroys quality of life, and can lead to fatal overdose. Numerous federal regulatory agencies have advised or mandated that healthcare systems and providers offer non-pharmacologic treatment options for pain. Acupuncture stands out as the most evidence-based, immediately available choice to fulfil these calls. Acupuncture can safely, easily, and cost-effectively be incorporated into hospital settings as diverse as the emergency department, labor and delivery suites, andneonatal intensive care units to treat a variety of commonly seen pain conditions. Acupuncture is already being successfully and meaningfully utilized by the Veterans Administration and various branches of the U.S. Military, in some studies demonstrably decreasing the volume of opioids prescribed when included in care.

关键词： acupuncture opioid epidemic pain opiate dependency effectiveness safety cost-effectiveness mechanism United States

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神秘石

新东方英语（中学版） 2006年第6期 56-57页

作者： lindsay

The cellular microenvironment modulates the role of PAI-1 and vitronectin in mediating cell-matrix interactions

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Advances in Biological Chemistry 2013年第1期3卷 114-132页

作者： Sumit Goswami Lawrence C. Thompson lindsay Wick.an Cynthia B. Peterson The Department of Biochemistry and Cellular and Molecular Biology The University of Tennessee Knoxville USA

Plasminogen activator inhibitor-1 (PAI-1), a member of the serine protease inhibitor (serpin) superfamily of proteins, circulates in a complex with vitronectin. Furthermore, these two proteins are co-localized in the extracellular matrix (ECM) in many different pathophysiological conditions. Though PAI-1 is a well-characterized inhibitor of serine proteases, recent emphasis has also focused on its protease-independent functions. Vitronectin, a multi-domain protein that binds a wide variety of ligands and proteins, exists in the circulation in a preferred monomeric state, while in the extracellular matrix it exists as a multimer resulting from an altered conformation. Though the mechanism for the conformational alterations and compartmentalization in tissues is unk.own, there are a number of biomolecules including PAI-1 that appear to cause such changes. Experimental analysis has established that PAI-1 induces association of vitronectin to higher-order species in a concentration-dependent fashion [1]. This report extends our investigations into the mechanism of the interaction between vitronectin and PAI-1 to explore the physiological relevance of these higher-order complexes for cellular adhesion and migration. In this study, we evaluate the effects of the pericellular microenvironment on the functions of the multimeric complexes in a variety of relevant biological settings. Our findings underscore the importance of the variability of components within this microenvironment, including different receptors and ECM components, in governing the way in which the vitronectin/PAI-1 complex mediates cell-matrix interactions.

关键词： PAI-1 Vitronectin Extracellular Matrix Receptors

The management and control of quality James R. Evans

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The management and control of quality James R. Evans

1000年

作者： William M. lindsay.

来源：畅想之星图书光盘版（南... 评论

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访联合国秘书长科菲·安南

新东方英语（中英文版） 2006年第9期 92-95页

作者： lindsay

科菲·安南(k.fiAnnan)1938年4月8日出生于加纳的库马西市,先后获美国明尼苏达州麦卡莱斯特学院经济学学士学位和麻省理工学院管理学硕士学位。1996年12月17日,第51届联大任命安南为联合国第七任秘书长。1997年1月1日,他正式就职,任期5... 详细信息

科菲·安南(k.fiAnnan)1938年4月8日出生于加纳的库马西市,先后获美国明尼苏达州麦卡莱斯特学院经济学学士学位和麻省理工学院管理学硕士学位。1996年12月17日,第51届联大任命安南为联合国第七任秘书长。1997年1月1日,他正式就职,任期5年。2001年6月,联大通过安理会提名安南连任秘书长,任期至2006年12月31日。2001年10月,安南与联合国同获当年诺贝尔和平奖。2006年5月19日,安南到达北京与我国国家主席胡锦涛进行了会面,开始了对中国为期5天的访问。以下是科菲·安南接受“高端访问”栏目专访的部分内容。

关键词：联合国秘书长安南联合国维和行动安理会工作人员联合国改革访问麻省理工学院任期经济学

Cystic fibrosis patients on cystic fibrosis transmembrane conductance regulator modulators have a reduced incidence of cirrhosis

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World Journal of Hepatology 2022年第2期14卷 411-419页

作者： Mitchell L Ramsey Michael R Wellner k.le Porter Stephen E k.rk.y Susan S Li Luis F Lara Sean G k.lly A James Hanje lindsay A Sobotk. Department of Gastroenterology Hepatology and NutritionThe Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Gastroenterology Hepatology and NutritionThe Ohio State Wexner Medical CenterColumbusOH 43210United States Department of Biostatistics The Ohio State UniversityColumbusOH 43210United States Department of Pulmonary and Critical Care medicine The Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Internal medicine The Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Gastroenterology Hepatology and NutritionThe Ohio State UniversityColumbusOH 43210United States

BACk.ROUND Cystic fibrosis transmembrane conductance regulator(CFTR)modulators significantly improve pulmonary function in patients with cystic fibrosis(CF)but the effect on hepatobiliary outcomes remains *** hypothesized that CF patients on CFTR modulators would have a decreased incidence of cirrhosis compared to patients not on CFTR modulators or on *** To investigate the effect of CFTR modulators on the development of cirrhosis in patients with *** A retrospective analysis was performed using Truven Mark.tScan from January 2012 through December 2017 including all patients with a diagnosis of *** were excluded if they underwent a liver transplantation or if they had other etiologies of liver disease including viral hepatitis or alcohol *** were grouped by use of CFTR modulators,ursodiol,dual therapy,or no *** primary outcome was development of ***-Meier curves estimated the incidence of cirrhosis and log-rank.tests compared incidence curves between treatment *** A total of 7201 patients were included,of which 955(12.6%)used a CFTR modulator,529(7.0%)used ursodiol,105(1.4%)used combination therapy,and 5612(74.3%)used neither *** incidence of cirrhosis was 0.1%at 1 year and 0.7%at 4 years in untreated patients,5.9%and 10.1%in the Ursodiol group,and 1.0%and 1.0%in patients who received both *** patient treated with CFTR modulators alone developed *** on CFTR modulators alone had lower cirrhosis incidence than untreated patients(P=0.05),patients on Ursodiol(P<0.001),and patients on dual therapy(P=0.003).The highest incidence of cirrhosis was found among patients treated with Ursodiol alone,compared to untreated patients(P<0.001)or patients on Ursodiol and CFTR modulators(P=0.01).CONCLUSION CFTR modulators are associated with a reduction in the incidence of cirrhosis compared to other therapies in patients with CF.

关键词： Cirrhosis Ursodiol Transmembrane Cystic fibrosis Mark.t scan Cystic fibrosis related liver disease

中国1型糖尿病的社会成见:请停止对这种可控慢性病患者的歧视

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中国糖尿病杂志 2015年第3期23卷 195-197页

作者：刘蔚纪立农苏夜阳 lindsay M.Jaack. Elizabeth J.Mayer-Davis 北京大学人民医院内分泌科 100044 University of Sussex Department of Nutrition The University of North CarolinaChapel HillNCUSA

社会成见(也称"污名化")是阻碍1型糖尿病患者得到更好医疗保障的顽固壁垒。这篇述评描述了目前中国存在的针对1型糖尿病患者的社会成见现象。在中国,社会成见给1型糖尿病患者带来歧视和对个体的贬低。1型糖尿病患者因社会成见在择偶、... 详细信息

社会成见(也称"污名化")是阻碍1型糖尿病患者得到更好医疗保障的顽固壁垒。这篇述评描述了目前中国存在的针对1型糖尿病患者的社会成见现象。在中国,社会成见给1型糖尿病患者带来歧视和对个体的贬低。1型糖尿病患者因社会成见在择偶、升学、就业中遭受的不公正待遇迫使很多患者隐瞒他们的疾病。社会成见给1型糖尿病患者带来的耻辱感、恐惧感和负罪感会妨碍他们应用能更好地控制血糖的胰岛素泵或每日多次皮下注射胰岛素来管理血糖,因为运用这些治疗方法会要求患者在学校或工作单位进行餐前胰岛素注射和血糖监测。同时,社会成见也使他们不愿参加与1型糖尿病相关的科研活动,或那些可能让他们获益的健康促进活动。目前亟需多方面、多层次的行动来改变这种社会成见。这包括:提高公众对于1型糖尿病的认识和理解;医疗工作者从整体医疗而不是仅从生物医学角度出发来管理1型糖尿病;辅导患者发展积极应对的技能;考虑到中国现实的社会心理环境,扩展1型糖尿病研究的范围。近期,在中国全国播出的一部关于1型糖尿病的纪录片,正是朝向这正确方向迈进的重要一步。我们相信,通过协调各相关方的行动,终会给1型糖尿病的治疗带来重要的改善、提高这些身患慢性但可控疾病患者的身心健康。

关键词： 1型糖尿病社会成见歧视中国