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ECNU Review of Education 2024年第2期7卷 283-307页

作者：曾成 linda Fisher 184 Hills Road Cambridge CB28PQUK

Purpose:Mobile-assisted language learning(MALL)apps such as Duolingo have great potential for promoting learners'motivation to learn a second language(L2).However,little research has investigated how this motivational impact takes ***,despite the flexibility of mobile learning,most existing studies are conducted in classroom settings,with less attention paid to out-of-school technology ***/Approach/Methods:To address these gaps,we present a model based on self-determination theory and propose the idea of“motivational transfer”to explain the psychological mechanism underpinning the impact of *** examine the model,we conducted a case study with 20 Year 8 Chinese junior school students who used Duolingo to learn English as a foreign language(EFL)after school for 6 ***:Questionnaire and group interview data support our hypothesized mechanism:learners'activity-specific intrinsic motivation(IM)for using Duolingo and their underlying psychological need for autonomy and competence can be transferred to a more general level,thereby enhancing learners'global ***:The proposed theoretical model expands our understanding of how digital technology stimulates learners'L2 motivation;it can help L2 educators design better technological affordances to promote learners'motivation both in and outside the classroom.

关键词： Digital game-based learning L2 motivation MALL self-determination theory

Reinventing Systems for Equity

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ECNU Review of Education 2024年第2期7卷 214-229页

作者： linda Darling-Hammond Learning Policy Institute I530 Page Mill Road SuitePalo AltoCAUSA

Highlights Around the world,nations are grappling with the longstanding inequalities in education and society that were made more visible during the pandemic-along with the increasing educational demands of our fast-changing,knowledge-based *** article outlines the anatomy of educational inequality and the demands for students to develop“learning ability.”

关键词： Educational equity education reform teacher development

A Comprehensive Survey for Privacy-Preserving Biometrics: Recent Approaches, Challenges, and Future Directions

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Computers, Materials & Continua 2024年第2期78卷 2087-2110页

作者： Shahriar Md Arman Tao Yang Shahadat Shahed Alanoud AlMazroa Afraa Attiah linda Mohaisen School of Computer Science and Technology Zhejiang Gongshang UniversityHangzhou310018China School of Computer Science and Technology Hangzhou Dianzi UniversityHangzhou310018China College of Computer and Information Sciences Princess Nourah bint Abdulrahman UniversityRiyadh84428Saudi Arabia Faculty of Computing and Information Technology King Abdulaziz UniversityJeddah21589Saudi Arabia

The rapid growth of smart technologies and services has intensified the challenges surrounding identity authenti-cation *** credentials are increasingly being used for verification due to their advantages over traditional methods,making it crucial to safeguard the privacy of people’s biometric data in various *** paper offers an in-depth exploration for privacy-preserving techniques and potential threats to biometric *** proposes a noble and thorough taxonomy survey for privacy-preserving techniques,as well as a systematic framework for categorizing the field’s existing *** review the state-of-the-art methods and address their advantages and limitations in the context of various biometric modalities,such as face,fingerprint,and eye *** survey encompasses various categories of privacy-preserving mechanisms and examines the trade-offs between security,privacy,and recognition performance,as well as the issues and future research *** aims to provide researchers,professionals,and decision-makers with a thorough understanding of the existing privacy-preserving solutions in biometric recognition systems and serves as the foundation of the development of more secure and privacy-preserving biometric technologies.

关键词： Biometric modalities biometric recognition biometric security privacy-preserving security threats

Dual mobility in primary total hip arthroplasty:A temptation from the devil or a blessing from above

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World Journal of Orthopedics 2024年第6期15卷 512-519页

作者： Raymond Klumpp linda Boerci Francesco Buonanotte Marco Zeppieri Unita Operativa Complessa Ortopedia e Traumatologia Ospedale Treviglio-Caravaggio ASSTBergamo Ovest 24047Italy Department of Orthopedics Universitàdegli Studi di Milano-BicoccaMonza 20090Italy Department of Ophthalmology University Hospital of UdineUdine 33100Italy

Dual mobility(DM)bearings have gained significant attention in the field of total hip arthroplasty(THA)as a valid treatment option in cases of revision for instability after THA whereas its use in primary THA is still a matter of *** manuscript explores the pathology,incidence,diagnosis,treatment options,prognosis,ongoing studies in the literature,and future perspectives related to the use of DM bearings employed in primary *** bearings are primarily designed to address one of the major concerns in THA:Instability of the prosthetic *** is both for the surgeon and the patient a devastating postoperative complication,leading to significant pain and subsequent apprehension by the patient and may require revision *** use of DM implants poses the worry of wear-related complications,such as accelerated polyethylene wear and osteolysis,which also pose challenges to long-term implant *** technique has seen a steady rise in recent years,with multiple studies reporting favorable *** incidence of their utilization varies among institutions and surgeons,reflecting differing preferences and patient *** diagnosis of instability and wear-related complications in THA often involves clinical assessment,imaging modalities such as X-rays,computed tomography scans,and sometimes advanced imaging techniques like magnetic resonance *** bearings can be considered as an option when patients present neurologic pathologies such as Parkinson's disease or recurrent dislocations after *** bearings provide an additional articulation point within the implant,facilitating a greater range of motion and inherent *** design allows for reduced risk of dislocation and improved functional *** implant manufacturers offer different designs and sizes of DM bearings to suit individual patient *** literature suggests that the use of DM bearings in primary THA has demonstrated promising outcomes in terms

关键词： Dual mobility First implant Hip arthroplasty Surgical technique Differential diagnosis

Shear-wave elastography to predict hepatocellular carcinoma after hepatitis C virus eradication:A systematic review and meta-analysis

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World Journal of Gastroenterology 2024年第10期30卷 1450-1460页

作者： Giorgio Esposto Paolo Santini linda Galasso Irene Mignini Maria Elena Ainora Antonio Gasbarrini Maria Assunta Zocco CEMAD Digestive Disease Center Fondazione Policlinico Universitario“A.Gemelli”IRCCSCatholic University of RomeRome 00168Italy Fondazione Policlinico Universitario Agostino Gemelli IRCCS Fondazione Policlinico Universitario Agostino Gemelli IRCCS-UniversitàCattolica del Sacro CuoreRome 00168Italy Medicina Interna e Gastroenterologia CEMAD Digestive Disease CenterUniversitàCattolica del Sacro CuoreFondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy

BACKGROUND Direct-acting antiviral agents(DAAs)are highly effective treatment for chronic hepatitis C(CHC)with a significant rate of sustained virologic response(SVR).The achievement of SVR is crucial to prevent additional liver damage and slow down fibrosis *** assessment of fibrosis degree can be performed with transient elastography,magnetic resonance elastography or shear-wave elastography(SWE).Liver elastography could function as a predictor for hepato-cellular carcinoma(HCC)in CHC patients treated with *** To explore the predictive value of SWE for HCC development after complete clearance of hepatitis C virus(HCV).METHODS A comprehensive literature search of clinical studies was performed to identify the ability of SWE to predict HCC occurrence after HCV *** accordance with the study protocol,a qualitative and quantitative analysis of the evidence was *** At baseline and after 12 wk of follow-up,a trend was shown towards greater liver stiffness(LS)in those who go on to develop HCC compared to those who do not[baseline LS standardized mean difference(SMD):1.15,95%confidence interval(95%CI):020-2.50;LS SMD after 12 wk:0.83,95%CI:0.33-1.98].The absence of a statistically significant difference between the mean LS in those who developed HCC or not may be related to the inability to correct for confounding factors and the absence of raw source *** was a statist-ically significant LS SMD at 24 wk of follow-up between patients who developed HCC vs not(0.64;95%CI:0.04-1.24).CONCLUSION SWE could be a promising tool for prediction of HCC occurrence in patients treated with *** studies with larger cohorts and standardized timing of elastographic evaluation are needed to confirm these data.

关键词： Shear-wave elastography Hepatocellular carcinoma Hepatitis C virus Sustained virologic response

Dynamic contrast enhanced ultrasound in differential diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2804-2815页

作者： Giorgio Esposto Paolo Santini Fabrizio Termite linda Galasso Irene Mignini Maria Elena Ainora Antonio Gasbarrini Maria Assunta Zocco Department of CEMAD Digestive Disease Center Fondazione Policlinico Universitario A Gemelli IRCCSCatholic University of RomeRome 00168Italy Department of Fondazione Policlinico Universitario Agostino Gemelli IRCCS UniversitàCattolica del Sacro CuoreRome 00168Italy Department of Medicina Interna e Gastroenterologia CEMAD Digestive Disease CenterFondazione Policlinico Universitario A Gemelli IRCCSUniversitàCattolica del Sacro CuoreRome 00168Italy

BACKGROUND Non-invasive differential diagnosis between hepatocellular carcinoma(HCC)and other liver cancer(*** or metastasis)is highly challenging and definitive diagnosis still relies on histological *** patterns of enhancement and wash-out of liver nodules can be used to stratify the risk of malignancy only in cirrhotic patients and HCC frequently shows atypical *** contrast-enhanced ultrasound(DCEUS)with standardized software could help to overcome these obstacles,providing functional and quantitative parameters and potentially improving accuracy in the evaluation of tumor *** To explore clinical evidence regarding the application of DCEUS in the differential diagnosis of liver *** A comprehensive literature search of clinical studies was performed to identify the parameters of DCEUS that could relate to histological *** accordance with the study protocol,a qualitative and quantitative analysis of the evidence was *** Rise time was significantly higher in HCC patients with a standardized mean difference(SMD)of 0.83(95%CI:0.48-1.18).Similarly,other statistically significant parameters were mean transit time local with a SMD of 0.73(95%CI:0.20-1.27),peak enhancement with a SMD of 0.37(95%CI:0.03-0.70),area wash-in area under the curve with a SMD of 0.47(95%CI:0.13-0.81),wash-out area under the curve with a SMD of 0.55(95%CI:0.21-0.89)and wash-in and wash-out area under the curve with SMD of 0.51(95%CI:0.17-0.85).SMD resulted not significant in fall time and wash-in rate,but the latter presented a trend towards greater values in HCC compared to intrahepatic *** DCEUS could improve non-invasive diagnosis of HCC,leading to less liver biopsy and early *** quantitative analysis needs to be applied on larger cohorts to confirm these preliminary results.

关键词： Dynamic contrast enhanced ultrasound Hepatocellular carcinoma Intracellular cholangiocarcinoma Quantitative ultrasound Liver cancer Time-intensity curve

The roles and mechanisms of SREBP1 in cancer development and drug response

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Genes & Diseases 2024年第4期11卷 258-269页

作者： Ying He Shasha Qi Lu Chen Jinyu Zhu linda Liang Xudong Chen Hao Zhang Lvjia Zhuo Shujuan Zhao Shuiping Liu Tian Xie School of Pharmacy Hangzhou Normal UniversityHangzhouZhejiang 311121China Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines Engineering Laboratory of Development and Application of Traditional Chinese MedicinesCollaborative Innovation Center of Traditional Chinese Medicines of Zhejiang ProvinceHangzhou Normal UniversityHangzhouZhejiang 311121China Laboratory of Cancer Genomics Division of Cellular and Molecular ResearchNational Cancer Centre SingaporeSingapore 169610Singapore

Cancer occurrence and development are closely related to increased lipid produc-tion and glucose *** are the basic component of the cell membrane and play a significant role in cancer cell processes such as cell-to-cell recognition,signal transduction,and energy supply,which are vital for cancer cell rapid proliferation,invasion,and *** regulatory element-binding transcription factor 1(SREBP1)is a key transcription factor regulating the expression of genes related to cholesterol biosynthesis,lipid homeostasis,and fatty acid *** addition,SREBP1 and its upstream or downstream target genes are implicated in various metabolic diseases,particularly ***,no review of sREBP1 in cancer biology has yet been ***,we summarized the roles and mechanisms of SREBP1 biological processes in cancer cells,including SREBP1 modification,lipid metabolism and reprogramming,glucose and mitochondrial metabolism,immunity,and tumor microenvi-ronment,epithelial-mesenchymal transition,cell cycle,apoptosis,and ***-ally,we discussed the potential role of SREBP1 in cancer prognosis,drug response such as drug sensitivity to chemotherapy and radiotherapy,and the potential drugs targeting SREBP1 and its corresponding pathway,elucidating the potential clinical application based on SREBP1 and its corresponding signal pathway.

关键词： Cancer Drug Lipid metabolism reprogramming Resistance SREBP1

A novel homozygous missense variant in ARSK causes MPS X,a new subtype of mucopolysaccharidosis

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Genes & Diseases 2024年第3期11卷 87-90页

作者： Miao Sun Cornelia K.Kaminsky Philip Deppe Mai-Brittllse Frederic M.Vaz Barbara Plecko Torben Lubke linda M.Randolph Division of Genomic Medicine Department of Pathology and Laboratory MedicineChildren's Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA Department of Radiology Children's Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA Department of Chemistry BiochemistryBielefeld UniversityBielefeld 33615Germany Amsterdam UMC Location University of Amsterdam Department of Clinical Chemistry and PediatricsLaboratory Genetic Metabolic DiseasesEmma Children's HospitalMeibergdreef 9Amsterdam 1100 DEthe Netherlands Amsterdam Gastroenterology Endocrinology Metabolism Inborn Errors of MetabolismAmsterdam 1105 BKthe Netherlands Core Facility Metabolomics Amsterdam UMC Location University of AmsterdamAmsterdam 1100DDthe Netherlands Department of Pediatrics Division of General PediatricsMedical Universityof GrazGraz8036Austria Division of Medical Genetics Department of PediatricsChildren's Hospital Los Angeles/Keck School of Medicine of USCLos AngelesCA 90027USA

Mucopolysaccharidoses(MPS)are a group of rare inborn errors of metabolism caused by defective lysosomal enzymes which prevent cells from degrading and recycling certain carbohydrates and fats,resulting in the storage of glycosaminoglycans in cells throughout the *** leads to multisystem abnormalities involving bone,connective tissues,brain,blood,spinal cord,skin,and other tissues.

关键词： metabolism doses polys

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涎腺基因转导的临床应用

中华口腔医学杂志 2009年第Z1期44卷 14-14页

作者： Bruce J Baum Changyu Zheng Llias Alevizos Ana P Cotrim Corinne M Goldsmith Shuying Liu linda mccullagh Nikolay Nikolov Gabor G Illei MolecularPhysiologyandTherapeuticsBranch NationalInstituteofDentalandCraniofacialResearch NIH DHHS Bethesda MD2190USA MolecularPhysiologyandTherapeuticsBranch NationalInstituteofDentalandCraniofacialResearch NIH DHHS Bethesda9USA MolecularPhysiologyandTherapeuticsBranch NationalInstituteofDentalandCraniofacialResearch NIH DHHS Bethesda MD2190USA MolecularPhysiologyandTherapeuticsBranch NationalInstituteofDentalandCraniofacialResearch NIH DHHS Bethesda9USA MolecularPhysiologyandTherapeuticsBranch NationalInstituteofDentalandCraniofacialResearch NIH DHHS Bethesda MD2190USA MolecularPhysiologyandTherapeuticsBranch NationalInstituteofDentalandCraniofacialResearch NIH DHHS Bethesda9USA MolecularPhysiologyandTherapeuticsBranch NationalInstituteofDentalandCraniofacialResearch NIH DHHS Bethesda MD2190USA MolecularPhysiologyandTherapeuticsBranch NationalInstituteofDentalandCraniofacialResearch NIH DHHS Bethesda9USA MolecularPhysiologyandTherapeuticsBranch NationalInstituteofDentalandCraniofacialResearch NIH DHHS Bethesda MD2190USA

一种文艺体式的劾覆:18、19世纪西方对元杂剧的发现、比较与衡量

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民族艺术 2024年第2期 158-168页

作者：廖琳达国家图书馆海外中国问题研究资料中心

西方对戏剧诗这一文艺体式的重视,促成了其18、19世纪对元杂剧的关注与探讨,并从西方文艺观、戏剧观、文学观和美学观出发,对元杂剧的戏剧结构、舞台演出形式、美学个性、文学与社会学价值进行追索,逐步确认了它的历史面貌。然而,西方... 详细信息

西方对戏剧诗这一文艺体式的重视,促成了其18、19世纪对元杂剧的关注与探讨,并从西方文艺观、戏剧观、文学观和美学观出发,对元杂剧的戏剧结构、舞台演出形式、美学个性、文学与社会学价值进行追索,逐步确认了它的历史面貌。然而,西方的早期戏曲研究从元杂剧切入,昧于时空差异把元杂剧体制视作中国戏曲的整体特征,基本无视当时中国舞台上与之共时态的明清戏曲,以及西方人秉持观念的差异与接受上的障碍,也造成其对于元杂剧乃至戏曲的跨文化误解与偏见。

关键词：元杂剧文艺体式戏剧跨文化域外汉学