检索结果-南通市图书馆

生物炭用量对烟草青枯病及土壤细菌群落的影响

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

核农学报 2024年第6期38卷 1186-1195页

作者：潘美清唐莉娜吴长征杨铭榆张汴泓黄锦文王成己作物遗传育种与综合利用教育部重点实验室/作物生态与分子生理学福建省高校重点实验室/福建农林大学农学院福建福州350002 福建省烟草专卖局烟草科学研究所福建福州350003 福建省农业科学院资源环境与土壤肥料研究所/福建省红壤山地农业生态过程重点实验室福建福州350013

为探究生物炭用量对烟草青枯病发生及土壤细菌群落结构和功能的影响,以植烟病圃土壤为研究对象,设置5个炭/土比0、1.5%、3.0%、4.5%、6.0%(记为TS0、TS15、TS30、TS45、TS60)的盆栽试验,研究烤烟青枯病发病情况、土壤农化性状、细菌群... 详细信息

为探究生物炭用量对烟草青枯病发生及土壤细菌群落结构和功能的影响,以植烟病圃土壤为研究对象,设置5个炭/土比0、1.5%、3.0%、4.5%、6.0%(记为TS0、TS15、TS30、TS45、TS60)的盆栽试验,研究烤烟青枯病发病情况、土壤农化性状、细菌群落结构与功能。结果表明,生物炭可有效减轻烟草青枯病发病情况,以炭/土比3.0%效果最佳。生物炭处理均可显著增加土壤pH值及有机质含量、改善土壤养分比例。冗余分析(RDA)结果表明,土壤pH值及养分是影响烟草青枯病的重要因子,提升土壤pH值及养分含量可有效减轻青枯病发生程度。进一步分析发现,生物炭可提高土壤细菌Alpha多样性,与对照相比,炭/土比1.5%~6.0%处理Chaol指数提高了8.24%~26.50%,变形菌门丰度分别增加了2.28、9.70、5.40、5.28个百分点,而酸杆菌门丰度分别降低了5.48、7.05、8.09、7.06个百分点。表型预测结果表明,生物炭可通过提高变形菌门丰度及降低酸杆菌门丰度来减少潜在致病菌丰度;与对照相比,炭/土比3.0%处理的芽孢杆菌属、鞘氨醇单胞菌属、出芽单胞菌属丰度分别增加5.77、0.24、0.36个百分点,罗河杆菌属丰度降低1.70个百分点,且雷尔氏菌属丰度随着施炭量的增加而逐渐减小。此外,生物炭可提高土壤氨基酸代谢、细胞生长与死亡功能类群丰度,且土壤pH值、有机质、速效钾、全素养分含量与氨基酸代谢、细胞生长与死亡功能具有正向效应,而罗河杆菌属与其具有负向效应。综上,生物炭可显著改善土壤养分比例,进而改善土壤细菌群落结构和功能特性、激发细菌群落氨基酸代谢等功能,提升烟株抗病性,减少青枯病的发生程度,以炭/土比3.0%~4.5%防控烟株青枯病效果较好。本研究结果为烟草种植中的病害防控和土壤改良提供了技术参考。

关键词：生物炭烟草青枯病土壤农化性状土壤细菌群落结构功能预测

维普期刊数据库博看期刊

Advantages of nanocarriers for basic research in the field of traumatic brain injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第2期19卷 237-245页

作者： Xingshuang Song Yizhi Zhang Ziyan tang lina Du School of Pharmaceutical Sciences Shandong University of Traditional Chinese MedicineJinanShandong ProvinceChina Department of Pharmaceutics Beijing Institute of Radiation MedicineBeijingChina

A major challenge for the efficient treatment of traumatic brain injury is the need for therapeutic molecules to cross the blood-brain barrier to enter and accumulate in brain *** overcome this problem,researchers have begun to focus on nanocarriers and other brain-targeting drug delivery *** this review,we summarize the epidemiology,basic pathophysiology,current clinical treatment,the establishment of models,and the evaluation indicators that are commonly used for traumatic brain *** also report the current status of traumatic brain injury when treated with nanocarriers such as liposomes and *** can overcome a variety of key biological barriers,improve drug bioavailability,increase intracellular penetration and retention time,achieve drug enrichment,control drug release,and achieve brain-targeting drug ***,the application of nanocarriers remains in the basic research stage and has yet to be fully translated to the clinic.

关键词： blood-brain barriers brain targeting central nervous system extracellular vesicles inflammatory factor microglial cell nanocarriers nanoparticles neural restoration traumatic brain injury

在线全文

学校读者我要写书评

暂无评论

大型物件海上运输系固方案校核的一般方法

广东造船 2024年第2期43卷 28-32页

作者：刘子聃孔祥锋张毅汤丽娜广州打捞局广州510290 中船黄埔文冲船舶有限公司广州510715

本文通过建立一个甲板运输驳船运输导管架的模型,使用理论计算的方法计算出大型物件在海运途中受到的荷载,对系固方案进行了校核,并采用有限元法对运输驳船船体与运输工装的强度进行校核。通过对该模型的完整计算,为大型物件海运系固方... 详细信息

本文通过建立一个甲板运输驳船运输导管架的模型,使用理论计算的方法计算出大型物件在海运途中受到的荷载,对系固方案进行了校核,并采用有限元法对运输驳船船体与运输工装的强度进行校核。通过对该模型的完整计算,为大型物件海运系固方案的校核提供了一般计算流程的参考,验证了该套系固方案校核对海洋工程行业的实用性。

关键词：大型物件海运系固方案强度校核

维普期刊数据库博看期刊

抑制水通道蛋白4表达对脑缺血再灌注模型小鼠自噬和凋亡的影响

在线全文

学校读者我要写书评

暂无评论

中国病理生理杂志 2024年第8期40卷 1446-1454页

作者：莫圣龙朱海燕陆志成莫嘉祺彭晓靖唐丽娜杨成敏简崇东商敬伟右江民族医学院附属医院神经内科广西百色533000 右江民族医学院研究生学院广西百色533000 广西高校桂西高发病临床分子诊断研究重点实验室广西百色533000

目的:探讨抑制水通道蛋白4(AQP4)表达对脑缺血再灌注模型小鼠自噬和凋亡的影响及其机制。方法:采用暂时性大脑中动脉闭塞(tMCAO)建立小鼠脑缺血再灌注损伤模型。将60只小鼠按随机数字表法分成假手术(sham)组、I/R组、AQP4抑制组和自噬... 详细信息

目的:探讨抑制水通道蛋白4(AQP4)表达对脑缺血再灌注模型小鼠自噬和凋亡的影响及其机制。方法:采用暂时性大脑中动脉闭塞(tMCAO)建立小鼠脑缺血再灌注损伤模型。将60只小鼠按随机数字表法分成假手术(sham)组、I/R组、AQP4抑制组和自噬抑制剂3-甲基腺嘌呤(3-MA)组,每组15只,sham组和I/R组腹腔注射生理盐水,AQP4抑制组和3-MA组分别腹腔注射AER-271(2 mg·kg^(-1)·d^(-1))和AER-271+3-MA(2 mg·kg_(-1)·d^(-1)),给药3 d,每天1次。观察各组小鼠神经功能Longa评分,记录体重变化;采用苏木精-伊红(HE)染色法观察脑梗死体积及组织病理变化;采用Western blot检测AQP4、LC3-Ⅱ、P62和cleaved caspase 3含量变化,采用免疫荧光法检测LC3-Ⅱ、P62、cleaved caspase-3与NeuN(神经元标志物)的共定位及表达情况。结果:I/R组与AQP4抑制组检测到大面积的脑梗塞和脑水肿,以及较高的Longa评分;与I/R组比较,AQP4抑制组的脑梗塞体积、脑水肿体积和Longa评分均显著降低(P<0.05);与sham组比较,I/R组的AQP4、LC3-Ⅱ和cleaved caspase-3的表达显著增加(P<0.01),而小鼠体重和P62表达则显著降低(P<0.05,P<0.01)。与I/R组比较,AQP4抑制组和3-MA组的AQP4、LC3-Ⅱ和cleaved caspase-3表达显著降低(P<0.05,P<0.01),而小鼠体重和P62表达则显著增加(P<0.05,P<0.01)。然而,与AQP4抑制组比较,3-MA组小鼠Longa评分、脑梗死体积、小鼠体重和AQP4、LC3-Ⅱ、cleaved caspase-3及P62的表达无显著差异。结论:抑制AQP4的表达能够显著减小tMCAO模型小鼠的脑梗死面积和减轻神经损伤程度。同时,抑制AQP4的表达对脑梗死后自噬和凋亡具有减缓作用,而加用自噬抑制剂后对AQP4抑制剂的保护作用无显著影响。

关键词：急性缺血性脑卒中细胞凋亡水通道蛋白4 细胞自噬脑缺血再灌注损伤

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

2195铝锂合金大型箱底热处理工艺研究

航天制造技术 2024年第2期 43-47页

作者：申世军唐丽娜吴杏苹栾浩张志超上海航天设备制造总厂有限公司上海200245

2195铝锂合金大型箱底的高性能整体制造是航天飞行器轻量化的迫切需求,针对采用新型充液拉深成形方式制造的大型箱底,固溶-成形-时效工艺设计及组织性能优化是箱底制造的关键问题。本文通过对2195铝锂合金固溶-充液拉深-时效工艺制造路... 详细信息

2195铝锂合金大型箱底的高性能整体制造是航天飞行器轻量化的迫切需求,针对采用新型充液拉深成形方式制造的大型箱底,固溶-成形-时效工艺设计及组织性能优化是箱底制造的关键问题。本文通过对2195铝锂合金固溶-充液拉深-时效工艺制造路线及热处理工艺试验,研究了不同热处理工艺下2195铝锂合金的力学性能和微观组织特征,揭示了箱底成形时的不均匀变形及热处理工艺参数等对构件性能和组织的影响规律,获得了2195铝锂合金大型箱底构件的热处理制度。

关键词： 2195铝锂合金固溶处理时效处理力学性能显微组织

维普期刊数据库博看期刊

基于响应面法的短切玄武岩纤维抹灰砂浆配合比设计

在线全文

学校读者我要写书评

暂无评论

混凝土 2024年第4期 103-110页

作者：章一萍刘星周练李碧雄唐丽娜农清舜方灵峰何华亮四川省建筑设计研究院有限公司四川成都610065 四川大学建筑与环境学院四川成都610065

为得到具有最佳力学性能且满足稠度要求的短切玄武岩纤维抹灰砂浆最优配合比,以水胶比、砂胶比、粉煤灰掺量为自变量,以砂浆稠度、抗拉强度、抗压强度、抗折强度为响应目标值,采用响应面法设计Box-Behnke试验,并建立回归模型,实现了满... 详细信息

为得到具有最佳力学性能且满足稠度要求的短切玄武岩纤维抹灰砂浆最优配合比,以水胶比、砂胶比、粉煤灰掺量为自变量,以砂浆稠度、抗拉强度、抗压强度、抗折强度为响应目标值,采用响应面法设计Box-Behnke试验,并建立回归模型,实现了满足既定目标稠度为70~110 mm的多目标综合优化,且对所提出的配合比进行验证试验。结果表明:水胶比对短切玄武岩纤维砂浆的稠度和强度有显著影响;最优配合比为水胶比0.35、砂胶比2.0、粉煤灰掺量20%时,其稠度、抗拉、抗压、抗折强度分别为97 mm、1.99 MPa、38.50 MPa、9.59 MPa;对于稠度和抗拉强度,回归模型的预测值和实测值误差低于4%,抗折强度及抗压强度的预测值和实测值误差分别为12%、28%,与玄武岩纤维混凝土抗压强度离散性大的特点一致,验证了响应面法对于短切玄武岩纤维抹灰砂浆配合比优化设计的可行性。

关键词：响应面法(RSM) 短切玄武岩纤维抹灰砂浆配合比优化稠度强度

Drone remote sensing for forestry research and practices

在线全文

学校读者我要写书评

暂无评论

Journal of Forestry Research 2015年第4期26卷 791-797页

作者： lina tang Guofan Shao Institute of Urban Environment Chinese Academy of Sciences Department of Forestry and Natural Resources Purdue University

Drones of various shapes, sizes, and functionalities have emerged over the past few decades, and their civilian applications are becoming increasingly appealing. Flexible, low-cost, and high-resolution remote sensing systems that use drones as platforms are important for filling data gaps and supplementing the capabilities of crewed/manned aircraft and satellite remote sensing systems. Here, we refer to this growing remote sensing ini- tiative as drone remote sensing and explain its unique advantages in forestry research and practices. Furthermore, we summarize the various approaches of drone remote sensing to surveying forests, mapping canopy gaps, mea- suring forest canopy height, tracking forest wildfires, and supporting intensive forest management. The benefits of drone remote sensing include low material and operational costs, flexible control of spatial and temporal resolution, high-intensity data collection, and the absence of risk to crews. The current forestry applications of drone remote sensing are still at an experimental stage, but they are expected to expand rapidly. To better guide the development of drone remote sensing for sustainable forestry, it isimportant to systematically and continuously conduct comparative studies to determine the appropriate drone remote sensing technologies for various forest conditions and/or forestry applications.

关键词： Drone - Remote sensing UAV UAS UA -RPA· Forest

The environmental analysis and site selection of mussel and large yellow croaker aquaculture areas based on high resolution remote sensing

在线全文

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 2024年第3期43卷 66-86页

作者： lina Cai Jie Yin Xiaojun Yan Yongdong Zhou Rong tang Menghan Yu Marine Science and Technology College Zhejiang Ocean UniversityZhoushan 316022China Zhejiang Marine Fisheries Research Institute Zhejiang Ocean UniversityZhoushan 316004China

Mussel aquaculture and large yellow croaker aquaculture areas and their environmental characteristics in Zhoushan were analyzed using satellite data and in-situ surveys.A new two-step remote sensing method was proposed and applied to determine the basic environmental characteristics of the best mussel and large yellow croaker aquaculture *** methodology includes the first step of extraction of the location distribution and the second step of the extraction of internal environmental *** fishery ranching index(FRI1,FRI2)was established to extract the mussel and the large yellow croaker aquaculture area in Zhoushan,using Gaofen-1(GF-1)and Gaofen-6(GF-6)satellite data with a special resolution of 2 *** the second step,the environmental factors such as sea surface temperature(SST),chlorophyll a(Chl-a)concentration,current and tide,suspended sediment concentration(SSC)in mussel aquaculture area and large yellow croaker aquaculture area were extracted and analyzed in *** results show the following three points.(1)For the extraction of the mussel aquaculture area,FRI1 and FRI2 are complementary,and the combination of FRI1 and FRI2 is suitable to extract the mussel aquaculture *** for the large yellow croaker aquaculture area extraction,FRI2 is suitable.(2)Mussel aquaculture and the large yellow croaker aquaculture area in Zhoushan are mainly located on the side near the islands that are away from the eastern open *** water environment factor template suitable for mussel and large yellow croaker aquaculture was determined.(3)This two-step remote sensing method can be used for the preliminary screening of potential site selection for the mussels and large yellow croaker aquaculture area in the *** fishery ranching index(FRI1,FRI2)in this paper can be applied to extract the mussel and large yellow croaker aquaculture areas in coastal waters around the world.

关键词： mussel aquaculture area large yellow croaker aquaculture area high resolution satellite site selection environmental analysis

An effective pharmacological hydrogel induces optic nerve repair and improves visual function

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第3期67卷 529-542页

作者： Lipeng Wang Shan Zhang Yawen Han Shuo tang Jiarui Li lina Bu Dongyu Zhao Hongkui Deng Department of Cell Biology Schoolof Basic Medical SciencesPeking University Stem Cell Research CenterStateKey Laboratoryof Naturaland Biomimetic DrugsPeking University Health Science Center Beijing 100191China MOE Key Laboratory of Cell Proliferation and Differentiation College of Life SciencesPeking-Tsinghua Center for Life SciencesPeking UniversityBeijing 100871China Academy for Advanced Interdisciplinary Studies Peking UniversityBeijing 100871China Changping Laboratory Beijing 102206China Department of Ophthalmology Peking University People's Hospital Eye Diseases and Optometry InstituteBeijing 100871China Department of Biomedical Informatics School of Basic Medical SciencesPeking UniversityBeijing 100191China

Irreversible eye lesions, such as glaucoma and traumatic optic neuropathy, can cause blindness;however, no effective treatments exist. The optic nerve, in particular, lacks the capacity to spontaneously regenerate, requiring the development of an effective approach for optic nerve repair, which has proven challenging. Here, we demonstrate that a combination of the small molecules 3BDO and trichostatin A(TSA)—which regulate mTOR and HDAC, respectively—packaged in thermosensitive hydrogel for 4-week-sustained release after intravitreal injection, effectively induced optic nerve regeneration in a mouse model of optic nerve crush injury. Moreover, this combination of 3BDO and TSA also protected axon projections and improved visual responses in an old mouse model(11 months old) of glaucoma. Taken together, our data provide a new, local small molecule-based treatment for the effective induction of optic nerve repair, which may represent a foundation for the development of pharmacological methods to treat irreversible eye diseases.

关键词： retinal ganglion cell axon regeneration old-age glaucoma small molecules pharmacological hydrogel visual function repair