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Mutual comparative analysis:a new topography-guided custom ablation protocol referencing subjective refraction to modify corneal topographic data

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Eye and Vision 2020年第4期7卷 347-355页

作者： Kaiwei Cao lina liu Tao Zhang Ting liu Ji Bai 77120 unit of People’s Liberation Army(PLA) No.1441 FengJu Ring RoadJinniu DistrictChengdu 610081China Chongqing vision institute No.77 Changjiang 2 RoadYuzhong DistrictChongqing 400042China Department of Ophthalmology Daping Hospital and the Research Institute of Surgery of the Army Medical University of PLANo.10 Changjiangzhi RoadYuzhong DistrictChongqing 400042China

Background:Several planning algorithms have been developed for topography-guided custom ablation treatment(T-CAT),but each has its own *** purpose of this study is to demonstrate the potential of a novel mutual comparative analysis(MCA)informed by manifest refraction and corneal topographic data and the patient’s subjective perception in correcting ***:This retrospective review included patients with significant preoperative differences in the power or axis of astigmatism according to the manifest refraction and corneal topographic data(power>0.75 D and/or axis>10°).T-CAT planning was designed using ***-ups were conducted for at least 6 ***:Seventy-nine patients(121 eyes)were *** mean preoperative deviation in the astigmatic power and axis were 0.72±0.43 D and 20.18±23.68°,*** average oculus residual astigmatism(ORA)was 0.81±0.32 D(range:0.08–1.66 D).Six months postoperatively,the mean spherical equivalent refraction was 0.04±0.42 D,and the mean cylinder was−0.27±0.24 *** mean efficacy and safety indices were 1.10 and 1.15,*** uncorrected distance visual acuity in 92%of the eyes was the same or better than the corrected distance visual *** angle of error was±5°in 61%of eyes and±15°in 84%of *** astigmatism was≤0.5 D in 91%of *** quality and photopic contrast sensitivity did not change significantly(p>0.05),and the scotopic contrast sensitivity decreased at 3,6,and 12 cpd(p<0.05).The vertical coma and horizontal coma of the anterior corneal surface significantly decreased postoperatively but increased during ***:The MCA demonstrated safety,efficacy,accuracy,predictability,and stability and can be used as a complementary and feasible method for T-CAT.

关键词： Mutual comparative analysis Topography-guided custom ablation treatment Astigmatism Manifest refraction Topography

Effects of highway construction on soil quality in the Longitudinal Range-Gorge Region in Yunnan Province

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Chinese Science Bulletin 2007年第A2期52卷 192-202页

作者： ZHAO ShuQing CUI BaoShan GAO lina liu Jie State Key Joint Laboratory of Environmental Simulation and Pollution Control School of Environment Beijing Normal UniversityBeijing 100875 China

在在西南的中国的纵的范围峡区域包围生态系统之上的高速公路建设的影响基于地调查和试验性的分析被检测。我们在达利上进行了研究(从达利城市到丽江城市)省的道路， Dabao (从达利城市到 Baoshan 城市)高速公路和 Baolong (从 Baoshan... 详细信息

在在西南的中国的纵的范围峡区域包围生态系统之上的高速公路建设的影响基于地调查和试验性的分析被检测。我们在达利上进行了研究(从达利城市到丽江城市)省的道路， Dabao (从达利城市到 Baoshan 城市)高速公路和 Baolong (从 Baoshan 城市到 Longling 县)在纵的范围峡区域的高速公路用包围土壤质量的 space-for-time 替换，和预言的补习的方法玷污质量在包围上检测高速公路建设的效果。结果显示出那：(1 ) 自然、栽培的土壤质量上的高速公路建设的效果是重要的，并且效果比在使用的高速公路的时期在高速公路建设的时期是更重要的。(2 ) 高速公路建设的效果是更明显的在上比 upslope，和效果范围下坡是 200 m 在上下坡，当时 upslope 上的 150 m。(3 ) 土壤补习主要与高速公路建设，高速公路服务时间，植被恢复，土壤有机物和土壤的效果程度有关全部的氮，在哪个之中，高速公路建设是最重要的因素。(4 ) 当植被范围能被恢复到 30% 原来的状况时，土壤质量罐头在 10 年以后被补救到 44% 原来的状况，一旦它被破坏，显示土壤富饶补习是相当困难的。

关键词：纵向岭谷区云南公路土壤

A single-center retrospective study on epidemiological and Traditional Chinese Medicine syndrome characteristics of 21010 patients with reflux/heartburn symptoms

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Journal of Traditional Chinese Medicine 2023年第3期43卷 574-581页

作者： TANG Yanping LI Peicai liu Xi liu Lei GONG Yanxia WEI Xiaodong liu lina YANG Li Department of Gastroenterology Tianjin Nankai HospitalTianjin 300100China

OBJECTIVE:To provide a basis for the clinical identification of true and false reflux,integrated traditional Chinese and Western medicine,and psychosomatic treatment,we conducted a retrospective study of the etiology and epidemiological and Traditional Chinese Medicine(TCM) syndrome characteristics of patients with reflux/heartburn ***:The 210 10 patients with reflux/heartburn treated at Tianjin Nankai Hospital from January 1,2016,to December 31,2019,were divided into four groups according to their ***,age,course of disease,incidence rate,gastroscopy,24-h p Himpedance,esophageal manometry,Hamilton Anxiety Scale(HAMA)/Hamilton Depression Scale(HAMD) score,8-week proton pump inhibitor(PPI) treatment effect,and TCM syndrome characteristics were statistically ***:A total of 21010 patients(8864 men and 12146 women),with reflux/heartburn symptoms were screened,including 6284(29.9%) patients with reflux esophagitis(RE),10427(49.6%) patients with nonerosive reflux esophagitis(NERD),2430(11.6%) patients with reflux hypersensitivity(RH),and 1870(8.9%) patients with functional heartburn(FH).The incidence of the disease was higher in women than in men(P RH > NERD > RE(P < 0.0001).There were more women than men in the groups with anxiety and more men than women in the groups with depression(P < 0.0001),and there was no significant difference in the distribution of anxiety and depression between men and women(P = 0.5689).There were significant differences in TCM syndrome characteristics between NERD,RE,and functional esophageal diseases(P < 0.01).The highest proportion of functional esophageal disease TCM symptoms was Qi stagnation and phlegm obstruction syndrome(36.16%),and there was no significant difference between RH and *** effective rates of PPI treatment at 8 weeks in patients in the RE,NERD,RH,and FH groups were 89%,72%,54%,and 0%,respect

关键词： gastroesophageal reflux esophagitis peptic hypersensitivity heartburn proton pump inhibitors emotional disorders syndrome complex

Fast growth of large single-crystalline WS_(2) monolayers via chemical vapor deposition

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Nano Research 2021年第6期14卷 1659-1662页

作者： Shengxue Zhou lina liu Shuang Cui Xiaofan Ping Dake Hu Liying Jiao Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education Department of ChemistryTsinghua UniversityBeijing100084China Department of Chemistry and Chemical Engineering Ningxia Normal UniversityGuyuan756000China Sinopec Beijing Research Institute of Chemical Industry Beijing100013China

Two-dimensional(2D)tungsten disulfide(WS2)has emerged as a promising ultrathin semiconductor for building high-performance nanoelectronic *** controllable synthesis of WS2 monolayers(1L)with both large size and high quality remains as a ***,we developed a new approach for the chemical vapor deposition(CVD)growth of WS2 monolayers by using K2WS4 as the growth *** simple chemistry involved in our approach allowed for improved controllability and a fast growth rate of~30μm·min−*** achieved the reliable growth of 1L WS2 flakes with side lengths of up to~500μm and the obtained WS2 flakes were 2D single crystals with low density of defects over a large area as evidenced by various spectroscopic and microscopic *** addition,the large 1L WS2 single crystals we obtained showed higher electrical performance than their counterparts grown with previous approaches,demonstrating the potential of our approach in producing high quality and large 2D semiconductors for future nanoelectronics.

关键词： tungsten disulfide two-dimensional chemical vapor deposition field effect transistors

Vegetation stability during the last two centuries on the western Tibetan Plateau:a palynological evidence

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Frontiers of Earth Science 2023年第4期17卷 1049-1058页

作者： Yanrong ZHANG Nannan WANG lina liu Mingda WANG Xiaoshan YU Xianyong CAO Alpine Paleoecology and Human Adaptation Group(ALPHA) State Key Laboratory of Tibetan Plateau Earth SystemEnvironment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Science Beijing 100049China School of Geography Liaoning Normal UniversityDalian 116029China

Investigating the dynamics of vegetation is an essential basis to know how to protect ecological environments and to help predict any changes in *** of its fragile alpine ecosystem,the Tibetan Plateau is a particularly suitable area for studying vegetation changes and their driving *** this study,we present a high-resolution pollen record covering the last two centuries extracted from Gongzhu Co on the western Tibetan *** steppe is the predominant vegetation type in the surrounding area throughout the past 250 years with stable vegetation composition and abundance,as revealed by pollen spectra dominated by Artemisia,Ranunculaceae,Cyperaceae,and *** canonical correspondence analysis(DCCA)of the pollen data reveals low turnover in compositional species(0.41 SD),suggesting that the vegetation in the Gongzhu catchment had no significant temporal change,despite climate change and population increases in recent *** additionally ran DCCA on ten other pollen records from the Tibetan Plateau with high temporal resolution(1-20 years)covering recent centuries,and the results also show that compositional species turnover(0.15-0.81 SD)is relatively low,suggesting that the vegetation stability may have prevailed across the Tibetan Plateau during recent *** high-resolution pollen records and high taxonomic-resolution palaeo-vegetation records(such as sedaDNA),however,are needed to confirm the vegetation stability on the Tibetan Plateau.

关键词： pollen compositional 1species turnover vegetation change ecological stability

Fate of secondary effluent dissolved organic matter during soil-aquifer treatment

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Chinese Science Bulletin 2007年第18期52卷 2496-2505页

作者： XUE Shuang ZHAO QingLiang WEI LiangLiang WANG lina liu ZhiGang School of Municipal and Environmental Engineering Harbin Institute of Technology Harbin 150090 China

The reduction of mass and trihalomethane formation potential (THMFP) of dissolved organic matter (DOM) and its fractions from secondary effluent during laboratory-scale soil-aquifer treatment (SAT) soil columns were studied. Reduction in dissolved organic carbon (DOC), absorbance of ultraviolet light at 254 nm (UV-254), biodegradable dissolved organic carbon (BDOC) and nonbiodegradable dis- solved organic carbon (NBDOC) for the bulk DOM averaged 72.35%, 53.98%, 97.49% and 35.33% across the soil columns, respectively. Using XAD-8 and XAD-4 resins, DOM was fractionated into 3 fractions: hydrophobic acid (HPO-A), transphilic acid (TPI-A) and hydrophilic fraction (HPI). HPO-A was removed by 61.06%, TPI-A by 54.86% and HPI by 74.95% as DOC as a consequence of the laboratory-scale SAT, respectively. The reduction of THMFP from HPO-A, TPI-A and HPI was 27.24%, 26.24% and 36.08%, respectively. Proton nuclear magnetic resonance (1H-NMR) spectra revealed that the HPO-A isolated from the secondary effluent contained more aromatic functional groups than the corresponding TPI-A. Fourier-transform infrared (FT-IR) spectrum analysis illustrated that TPI-A had decreased hydrocarbon and increased aromatics content in the SAT columns. Specific ultraviolet light absorbance (SUVA) and specific THMFP for each DOM fraction increased across the soil columns and HPI exhibited greater increase in both than HPO-A and TPI-A. The most problematic THM precursor was found to be HPO-A with its high quantity present in recharged water and high chlorine reactivity.

关键词：溶解有机物生物降解能力三卤代甲烷封款式污染

Heterologous expression of Hp BHY and Cr BKT increases heat tolerance in Physcomitrella patens

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Plant Diversity 2019年第4期41卷 266-274页

作者： Jianfang He Ping Li Heqiang Huo lina liu Ting Tang Mingxia He Junchao Huang Li liu Key Laboratory of Economic Plants and Biotechnology Kunming Institute of BotanyChinese Academy of SciencesYunnan Key Laboratory for Wild Plant ResourcesKunming650201China University of Chinese Academy of Sciences Beijing100049China Mid-Florida Research and Education Center Department of Environmental HorticultureUniversity of FloridaFL32703USA

Heat stress can restrict plant growth,development,and crop *** essential plant antioxidants,carotenoids play significant roles in plant stress resistance.b-carotene hydroxylase(BHY)and b-carotene ketolase(BKT),which catalyze the conversions of b-carotene to zeaxanthin and b-carotene to canthaxanthin,respectively,are key enzymes in the carotenoid biosynthetic pathway,but little is known about their potential functions in stress ***,we investigated the roles of b-carotene hydroxylase and b-carotene ketolase during heat stress in Physcomitrella patens through expressing a b-carotene ketolase gene from Chlamydomonas reinhardtii(Cr BKT)and a b-carotene hydroxylase gene from Haematococcus pluvialis(Hp BHY)in the moss *** transgenic moss expressing these genes,carotenoids content increased(especially lutein content),and heat stress tolerance increased,with reduced leafy tissue *** investigate the mechanism of this heat stress resistance,we measured various physiological indicators and found a lower malondialdehyde level,higher peroxidase and superoxide dismutase activities,and higher endogenous abscisic acid and salicylate content in the transgenic plants in response to high-temperature *** results demonstrate that Cr BKT and Hp BHY increase plant heat stress resistance through the antioxidant and damage repair metabolism,which is related to abscisic acid and salicylate signaling.

关键词： Carotenoids Heat stress Antioxidant Abscisic acid Physcomitrella patens

A temporal gene expression map of Chrysanthemum leaves infected with Alternaria alternata reveals different stages of defense mechanisms

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Horticulture Research 2020年第1期7卷 2404-2417页

作者： Ye liu Jingjing Xin lina liu Aiping Song Zhiyong Guan Weimin Fang Fadi Chen State Key Laboratory of Crop Genetics and Germplasm Enhancement Key Laboratory of LandscapingMinistry of Agriculture and Rural AffairsCollege of HorticultureNanjing Agricultural UniversityNanjingChina

Chrysanthemum(Chrysanthemum morifolium)black spot disease(CBS)poses a major threat to Chrysanthemum cultivation owing to suitable climate conditions and current lack of resistant cultivars for greenhouse *** this study,we identified a number of genes that respond to Alternaria alternata infection in resistant and susceptible Chrysanthemum *** on RNA sequencing technology and a weighted gene coexpression network analysis(WGCNA),we constructed a model to elucidate the response of Chrysanthemum leaves to *** infection at different stages and compared the mapped response of the resistant cultivar‘Jinba’to that of the susceptible cultivar‘Zaoyihong’.In the early stage of infection,when lesions had not yet formed,abscisic acid(ABA),salicylic acid(SA)and EDS1-mediated resistance played important roles in the Chrysanthemum defense *** the formation of necrotic lesions,ethylene(ET)metabolism and the Ca^(2+)signal transduction pathway strongly responded to *** *** the late stage,when necrotic lesions continued to expand,members of the multidrug and toxic compound extrusion(MATE)gene family were highly expressed,and their products may be involved in defense against *** invasion by exporting toxins produced by the pathogen,which plays important roles in the pathogenicity of ***,the function of hub genes was verified by qPCR and transgenic *** identification of hub genes at different stages,the comparison of hub genes between the two cultivars and the highly expressed genes in the resistant cultivar‘Jinba’provide a theoretical basis for breeding cultivars resistant to CBS.

关键词： metabolism invasion breeding

Spatial distribution of charcoal in topsoil and its potential determinants on the Tibetan Plateau

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Frontiers of Earth Science 2023年第4期17卷 1059-1069页

作者： Yixuan WANG Chaoqun CAO Yanrong ZHANG lina liu Nannan WANG Wenjia LI Xianyong CAO Alpine Paleoecology and Human Adaptation Group(ALPHA) State Key Laboratory of Tibetan Plateau Earth SystemEnvironment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China University of the Chinese Academy of Sciences Beijing 100049China College of Life Sciences Zhejiang Normal UniversityJinhua 321004China

As an important proxy for investigating past fire activities,charcoal is often used to explore the characteristics of fire distribution and its relationships with vegetation,climate,and human *** into the spatial distribution and environmental determinants for charcoal,however,is still *** this study,we identified and counted charcoal from topsoil samples covering the Tibetan Plateau using the pollen methodology,and investigated its relationships with vegetation net primary production(NPP),elevation,climate(precipitation,mean temperature of the coldest month and warmest month)and human population by boosted regression trees(BRT).Results reveal that the concentration of microscopic charcoal,macroscopic charcoal,and total charcoal all increase from south-west to north-east,which is consistent with the trend that the population density on the Tibetan Plateau is high in the east and low in the west,suggesting that an increase in human activity is likely to promote the occurrence of *** BRT modeling reveals that NPP,elevation,and mean temperature of the coldest month are important factors for total charcoal concentration on the Tibetan Plateau,and the frequency and intensity of fires further increase with increasing vegetation biomass,decreasing elevation,and decreasing mean temperature of the coldest *** spatial variation characteristics of charcoal from topsoil on the Tibetan Plateau not only reflect well the spatial fire situation in the region,but also have a good indicative significance for vegetation,climate,and human activities.

关键词： BRT charcoal fire regime climate vegetation human activities