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I/O Efficient Early Bursting Cohesive Subgraph Discovery in Massive Temporal Networks

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Journal of Computer Science & Technology 2022年第6期37卷 1337-1355页

作者： Yuan Li Jie Dai xiao-lin fan Yu-Hai Zhao Guo-Ren Wang School of Information Science and Technology North China University of TechnologyBeijing 100144China School of Computer Science and Engineering Northeastern UniversityShenyang 110169China School of Computer Beijing Institute of TechnologyBeijing 100081China

Temporal networks are an effective way to encode temporal information into graph data *** the bursting cohesive subgraph(BCS),which accumulates its cohesiveness at the fastest rate,is an important problem in temporal *** BCS has a large number of applications,such as representing emergency events in social media,traffic congestion in road networks and epidemic outbreak in ***,existing methods demand the BCS lasting for a time interval,which neglects the timeliness of the *** this paper,we design an early bursting cohesive subgraph(EBCS)model based on the k-core to enable identifying the burstiness as soon as *** find the EBCS,we first construct a time weight graph(TWG)to measure the bursting level by integrating the topological and temporal ***,we propose a global search algorithm,called GS-EBCS,which can find the exact EBCS by iteratively removing nodes from the ***,we propose a local search algorithm,named LS-EBCS,to find the EBCS by first expanding from a seed node until obtaining a candidate k-core and then refining the k-core to the result subgraph in an optimal time ***,considering the situation that the massive temporal networks cannot be completely put into the memory,we first design an I/O method to build the TWG and then develop I/O efficient global search and local search algorithms,namely I/O-GS and I/O-LS respectively,to find the EBCS under the semi-external *** experiments,conducted on four real temporal networks,demonstrate the efficiency and effectiveness of our proposed *** example,on the DBLP dataset,I/O-LS and LS-EBCS have comparable running time,while the maximum memory usage of I/O-LS is only 6.5 MB,which is much smaller than that of LS-EBCS taking 308.7 MB.

关键词： early bursting cohesive subgraph(EBCS) I/O efficient algorithm semi-external model temporal network

Therapeutic potential of menstrual blood stem cells in treating acute liver failure

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World Journal of Gastroenterology 2019年第41期25卷 6190-6204页

作者： Pan-Pan Cen lin-xiao fan Jie Wang Jia-Jia Chen Lan-Juan Li Department of Infectious Diseases Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006Zhejiang ProvinceChina State Key Laboratory for Diagnosis and Treatment of Infectious Diseases/National Clinical Research Center for Infectious Diseases/The First Affiliated Hospital Zhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina

BACKGROUND Acute liver failure(ALF)is a significant and complex hepatic insult that may rapidly progress to life-threatening ***,menstrual blood stem cells(MenSCs)have been identified as a group of easily accessible mesenchymal stem cells with the advantages of non-invasive acquisition,low immunogenicity,a greater capacity of self-renewal and multi-lineage differentiation,making them promising candidates for stem cell-based therapy to revolutionize the treatment strategies for liver *** To investigate the therapeutic potential of MenSCs for treating ALF in pigs and to dynamically trace the biodistribution of transplanted *** MenSCs were labeled in vitro with PKH26,a lipophilic fluorescent *** treatment group received immediate transplantation of PKH26-labelled MenSCs(2.5×106/kg)via the portal vein after D-galactosamine injection,and the control group underwent sham *** survival time,liver function,and hepatic pathological changes were compared between the two *** major organs(liver,lungs and spleen)were extracted from animals and imaged directly with the In vivo Imaging System(IVIS)at the predetermined time *** regions of interest were drawn to quantify the cell uptake in different *** The labelling procedure did not affect the morphology,viability or multipotential differentiation of *** analysis showed that the levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST),total bilirubin(TBIL)and prothrombin time(PT)measured at selected time points 24 h after transplantation were significantly decreased in the treatment group(P<0.05).The survival time of ALF animals was prolonged in the treatment group compared with the control group(75.75±5.11 h vs 53.75±2.37 h,log rank,P<0.001).The liver pathological tissue in the MenSC treatment group showed obviously increased numbers of remaining hepatocytes and a comparatively slight necrotic degree and *** addition,the IV

关键词： Menstrual blood stem cell Acute liver failure Cell transplantation Homing Labelling

Unmasking Social Robots’Camouflage:A GNN-Random Forest Framework for Enhanced Detection

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Computers, Materials & Continua 2025年第1期82卷 467-483页

作者： Weijian fan Chunhua Wang xiao Han Chichen lin School of Data Science and Intelligent Media Communication University of ChinaBeijing100024China School of Computer and Cyber Sciences Communication University of ChinaBeijing100024China Institute of Communication Studies Communication University of ChinaBeijing100024China State Key Laboratory of Media Convergence and Communication Communication University of ChinaBeijing100024China

The proliferation of robot accounts on social media platforms has posed a significant negative impact,necessitating robust measures to counter network anomalies and safeguard content *** robot detection has emerged as a pivotal yet intricate task,aimed at mitigating the dissemination of misleading *** graphbased approaches have attained remarkable performance in this realm,they grapple with a fundamental limitation:the homogeneity assumption in graph convolution allows social robots to stealthily evade detection by mingling with genuine human *** unravel this challenge and thwart the camouflage tactics,this work proposed an innovative social robot detection framework based on enhanced HOmogeneity and Random Forest(HORFBot).At the core of HORFBot lies a homogeneous graph enhancement strategy,intricately woven with edge-removal techniques,tometiculously dissect the graph intomultiple revealing ***,leveraging the power of contrastive learning,the proposed methodology meticulously trains multiple graph convolutional networks,each honed to discern nuances within these tailored *** culminating stage involves the fusion of these feature-rich base classifiers,harmoniously aggregating their insights to produce a comprehensive detection *** experiments on three social robot detection datasets have shown that this method effectively improves the accuracy of social robot detection and outperforms comparative methods.

关键词： Social robot detection graph neural networks random forest homophily heterophily

Design, synthesis and herbicidal activities of novel self-dispreading phenoxy carboxylic acid derivatives for the control of water hyacinth floating on the water surface

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Chinese Chemical Letters 2015年第8期26卷 1008-1010页

作者： Lv-Yin Zheng Ren-Miao Wu Wei Guo Wen-Hua You Yan-Lan ling xiao-lin fan Key Laboratory of Organo-pharmaceutical Chemistry of Jiangxi Province Gannan Normal University

A series of novel self-dispreading phenoxy carboxylic acid derivatives were designed and synthesized by I2 catalyzed one-step reaction. Their structures were confirmed by IR, NMR, and HRMS. The derivatives can self-spread and float on the water surface. Preliminary bioassays showed that some compounds, 3i–3p, had excellent herbicidal activities against water hyacinth. This strategy provided a novel approach for the water hyacinth control.

关键词： phenoxy carboxylic floating catalyzed spread afford facile benzene acetic tetra

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一种获取非相干分布源空间分布的算法

电子与信息学报 2014年第2期36卷 260-265页

作者：林晓帆韦岗华南理工大学电子与信息学院广州510640

多数分布式信号源DOA估计算法是估计中心到达角和分布参数,不能获取真实的分布曲线,而且可能需要2维搜索,运算量大。该文在假设分布曲线形状为钟形对称的前提下,提出一种求非相干分布式信号源空间分布的算法。该算法引入稀疏信号重建作... 详细信息

多数分布式信号源DOA估计算法是估计中心到达角和分布参数,不能获取真实的分布曲线,而且可能需要2维搜索,运算量大。该文在假设分布曲线形状为钟形对称的前提下,提出一种求非相干分布式信号源空间分布的算法。该算法引入稀疏信号重建作为数学工具,在阵元数充足的条件下能求解多个信号源的分布,在阵元数较少时也能得到近似求解。此外,该算法估计中心到达角的性能不逊于现存算法,且无需2维搜索,运算量低。仿真验证了以上结论。

关键词：阵列信号处理 DOA估计非相干分布源稀疏重建

Intelligent diagnosis of jaundice with dynamic uncertain causality graph model

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2017年第5期18卷 393-401页

作者： Shao-rui HAO Shi-chao GENG lin-xiao fan Jia-jia CHEN Qin ZHANG Lan-juan LI State Key Laboratory for Diagnosis and Treatment of Infectious Diseases Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases the First Affiliated Hospital School of Medicine Zhejiang University School of Communication Shandong Normal University School of Computer Science and Engineering Beihang University

Jaundice is a common and complex clinical symptom potentially occurring in hepatology, general surgery, pediatrics, infectious diseases, gynecology, and obstetrics, and it is faidy difficult to distinguish the cause of jaundice in clinical practice, especially for general practitioners in less developed regions. With collaboration between physicians and artificial intelligence engineers, a comprehensive knowledge base relevant to jaundice was created based on demographic information, symptoms, physical signs, laboratory tests, imaging diagnosis, medical histories, and risk factors. Then a diagnostic modeling and reasoning system using the dynamic uncertain causality graph was proposed. A modularized modeling scheme was presented to reduce the complexity of model construction, providing multiple perspectives and arbitrary granularity for disease causality representations. A ＂chaining＂ inference algorithm and weighted logic operation mechanism were employed to guarantee the exactness and efficiency of diagnostic rea- soning under situations of incomplete and uncertain information. Moreover, the causal interactions among diseases and symptoms intuitively demonstrated the reasoning process in a graphical manner. Verification was performed using 203 randomly pooled clinical cases, and the accuracy was 99.01% and 84.73%, respectively, with or without laboratory tests in the model. The solutions were more explicable and convincing than common methods such as Bayesian Networks, further increasing the objectivity of clinical decision-making. The promising results indicated that our model could be potentially used in intelligent diagnosis and help decrease public health expenditure.

关键词： Jaundice Intelligent diagnosis Dynamic uncertain causality graph Expert system

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基于网络的辅助设计系统构建

微电子学与计算机 2007年第7期24卷 163-165页

作者：林晓凡林琳西安工业大学机电工程学院陕西西安710032 西安工业大学经济管理学院陕西西安710032

基于计算机网络技术设计了一个辅助设计系统,其核心是Web工程数据库的设计与调用。说明了系统的总体构架,详细论述了数据库的设计步骤及模块组成,以及对数据库的异地调用方法与程序。本系统能初步实现网络下的CAD协同设计。

关键词：辅助设计数据库异地程序调用

Identification of overlay differentially expressed genes in both rats and goats with blast lung injury through comparative transcriptomics

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Chinese Journal of Traumatology 2024年第1期27卷 34-41页

作者： Hong Wang Jun-Hong Gao xiao-lin fan Qing Lu Liang Li Ning Ma Qi Wang Yu-Hao Zhang Xi'an Key Laboratory of Toxicology and Biological Effects Research Center for Toxicological and Biological EffectsInstitute for Hygiene of Ordnance IndustryXi'an710065China

Purpose:To identify the potential target genes of blast lung injury(BLI)for the diagnosis and ***:This is an experimental *** BLI models in rats and goats were established by conducting a fuel-air explosive power test in an unobstructed environment,which was subsequently validated through hematoxylin-eosin *** sequencing was performed on lung tissues from both goats and *** expressed genes were identified using the criteria ofq≤0.05 and|log2 fold change|≥*** that,enrichment analyses were conducted for gene ontology and the Kyoto Encyclopedia of Genes and Genomes *** potential target genes were further confirmed through quantitative real-time polymerase chain reaction and enzyme linked immunosorbent ***:Observations through microscopy unveiled the presence of reddish edema fluid,erythrocytes,and instances of focal or patchy bleeding within the alveolar *** sequencing analysis identified a total of 83 differentially expressed genes in both rats and ***,49 genes exhibited a consistent expression pattern,with 38 genes displaying up-regulation and 11 genes demonstrating *** analysis highlighted the potential involvement of the interleukin-17 signaling pathway and vascular smooth muscle contraction pathway in the underlying mechanism of ***,the experimental findings in both goats and rats demonstrated a strong association between BLI and several key genes,including anterior gradient 2,ankyrin repeat domain 65,bactericidal/permeability-increasing fold containing family A member 1,bactericidal/permeability-increasing fold containing family B member 1,and keratin 4,which exhibited ***:Anterior gradient 2,ankyrin repeat domain 65,bactericidal/permeability-increasing fold containing family A member 1,bactericidal/permeability-increasing fold containing family B member 1,and keratin 4 hold potential as target genes

关键词： Blast lung injury Transcriptomic Target genes Differentially expressed genes

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基于滞后序列分析的智慧课堂教学行为研究

现代教育技术 2021年第7期31卷 55-61页

作者：彭林华林晓凡华南师范大学教育信息技术学院广东广州510631 广东省智慧学习工程技术研究中心广东广州510631

课堂教学行为分析有助于教师发现教学问题,并促进教学反思和教师专业发展。文章以10个小学主科的智慧课堂教学视频片段为研究样本,采用滞后序列分析方法对课堂教学行为进行分析,共得到3161个行为样本和21组显著行为序列,分析结果表明:... 详细信息

课堂教学行为分析有助于教师发现教学问题,并促进教学反思和教师专业发展。文章以10个小学主科的智慧课堂教学视频片段为研究样本,采用滞后序列分析方法对课堂教学行为进行分析,共得到3161个行为样本和21组显著行为序列,分析结果表明:两组教师在智慧课堂教学行为模式上存在显著差异,且分别映射浅层地使用、讲授式应用、导学式应用、反思性应用等四个层级的教师信息技术应用能力。基于此,文章提出智慧课堂教学行为的优化策略,以期提升智慧教室环境下教师的信息技术应用能力。

关键词：智慧教室课堂教学行为滞后序列分析教师信息技术应用能力