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Nano Research 2025年第1期18卷 607-617页

作者： Ruo-lin Jiang Hui-Na Liu Yu-Fan Yang Zhi-Cheng Zhang Qi Dai Xiao-Yan Bao lin-jie wu Ya-Xin Qin Xin Tan Xiao-Yan Sun Xu-Fang Ying Zhi-Qing Ben Min Han Institute of Pharmaceutics College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Department of Radiation Oncology Key Laboratory of Cancer Prevention and InterventionThe Second Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310058China Hangzhou Institute of Innovative Medicine Zhejiang UniversityHangzhou 310058China Jinhua Institute of Zhejiang University Jinhua 321299China National Key Laboratory of Advanced Drug Delivery and Release Systems Zhejiang UniversityHangzhou 310058China Polytechnic institute Zhejiang UniversityHangzhou 310015China

Traditionally,hyaluronic acid has been widely used for drug delivery,but the current application bottleneck is that hyaluronic acid is hydrophilic and electronegative,which makes it difficult to carry hydrophobic drugs and small interfering RNA(siRNA)with the same *** on previous studies,we designed and synthesized hyaluronic acid nanocarriers HA-spermine/N,N,N-trimethylcystamine/DOX-TPP(HSTD)for loading siRNA to overcome the problem of siRNA release caused by strong electrostatic ***,N,N,Ntrimethylcystamine in the carrier can be degraded by intracellular glutathione to completely and rapidly release siRNA,thus promoting ***,when codelivered with the chemotherapy drug doxorubicin(DOX),this novel nanocarrier showed promising synergy in inhibiting tumor growth.

关键词： zwitterionic hyaluronic acid N N N-trimethylcystamine small interfering RNA(siRNA) doxorubicin

A Comparison of Complete Genome Sequences of a Rabies Virus Chinese Isolate SH06 with the Vaccine Strains

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Virologica Sinica 2009年第6期24卷 529-536页

作者： Sheng-li MENG Ge-lin XU jie wu Xiao-Ming YANG Jia-Xin YAN Center of Rabies Diagnosis Wuhan Institute of Biological Products Wuhan 430060 China

In this study, we determined the complete nucleotide and deduced amino acid sequence of a primary isolate of rabies virus (SH06) obtained from the brain of a rabid dog. The overall length of the genome was 11 924 nucleotides. Comparison of the genomic sequence showed the homology of SH06 at nucleotide level with full-length genomes of reference vaccine strains ranged from 82.2% with the PV strain to 86.9% with the CTN strain. A full-length genome-based phylogenetic analysis was performed with sequences available from GenBank. Phylogenetic analysis of the complete genome sequences indicated that the SH06 exhibited the highest homology with rabies street virus BD06 and CTN vaccine strain originated from China.

关键词： Rabies virus Complete genome sequence Phylogenetic analysis

Nanostructured ZnO/BiVO_(4)I-scheme heterojunctions for piezocatalytic degradation of organic dyes via harvesting ultrasonic vibration energy

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 488-497页

作者： Yiling Li Xiaoyao Yu Yingjie Zhou Yao lin Ying wu Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua 321004China

BiVO_(4)porous spheres modified by ZnO were designed and synthesized using a facile two-step *** resulting ZnO/BiVO_(4)composite catalysts have shown remarkable efficiency as piezoelectric catalysts for degrading Rhodamine B(RhB)unde mechanical vibrations,they exhibit superior activity compared to pure *** 40wt%ZnO/BiVO_(4)heterojunction composite displayed the highest activity,along with good stability and *** enhanced piezoelectric catalytic activity can be attributed to the form ation of an I-scheme heterojunction structure,which can effectively inhibit the electron-hole ***,hole(h+)and superoxide radical(·O_(2)^(-))are proved to be the primary active ***,ZnO/BiVO_(4)stands as an efficient and stable piezoelectric catalyst with broad potential application in the field of environmental water pollution treatment.

关键词： piezoelectric catalytic heterojunction dye degradation ultrasonic vibration

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高光谱遥感在硅化带识别中的应用

科学技术与工程 2017年第3期17卷 154-158页

作者：郭帮杰张杰林武鼎张川核工业北京地质研究院遥感信息与图像分析技术国家级重点实验室北京100029

硅化带是多个矿种的找矿指示性信息,快速地大面积探测硅化带信息是遥感技术在地质找矿应用领域一项重要的应用。随着遥感技术的不断发展,针对不同的遥感数据,出现了多种不同的硅化带提取方法。首先通过分析JHU(约翰霍普金斯大学)波谱库... 详细信息

硅化带是多个矿种的找矿指示性信息,快速地大面积探测硅化带信息是遥感技术在地质找矿应用领域一项重要的应用。随着遥感技术的不断发展,针对不同的遥感数据,出现了多种不同的硅化带提取方法。首先通过分析JHU(约翰霍普金斯大学)波谱库中10多种不同Si O_2的岩性光谱特征,研究与Si O_2含量密切相关的波段;其次,使用热红外地面光谱仪102F实测的样品光谱和样品的地球化学数据(Si O_2含量),通过线性回归方程统计出Si O_2含量的计算公式;最后,使用该公式对TASI航空高光谱热红外数据进行处理,获取研究区Si O_2含量图,提取高Si O_2条带;并在进行野外验证。实验结果表明:8.62μm和9.25~9.5μm是Si O_2含量相关性极大的波段;TASI(thermal airborne hyperspectral imager)数据中有多个Si O_2对应的波谱特征,B6(8.62μm)的发射峰、B6两侧的斜坡及B14、B17左侧的斜坡与Si O_2呈正相关关系;该方法提取研究区高Si O_2条带非常精确,在花岗岩区亦能识别出硅化带。

关键词：高光谱遥感 TASI数据硅化带波谱特征喀木斯特

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： Xiao Xiang Feng Gao Yu-Gui Peng Peng wu Zong-lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

Locally Enhanced Flow and Electric Fields Through a Tip Effect for Efficient Flow‑Electrode Capacitive Deionization

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Nano-Micro Letters 2025年第2期17卷 1-17页

作者： Ziquan Wang Xiangfeng Chen Yuan Zhang jie Ma Zhiqun lin Amor Abdelkader Maria‑Magdalena Titirici Libo Deng College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060People’s Republic of China Research Center for Environmental Functional Materials College of Environmental Science and EngineeringTongji University1239 Siping RoadShanghai 200092People’s Republic of China Department of Chemical and Biomolecular Engineering National University of SingaporeSingapore 117585Singapore Department of Engineering Faculty of Science and TechnologyBournemouth UniversityTalbot CampusFern BarrowPooleEngland BH125BBUK Institut de Chimie de Nice UniversitéCôte d’AzurUMR CNRS 727228 Av.Valrose06108 NiceFrance Department of Chemical Engineering Imperial College LondonSouth Kensington CampusExhibition RdLondon SW72AZUK

Low-electrode capacitive deionization(FCDI)is an emerging desalination technology with great potential for removal and/or recycling ions from a range of ***,it still suffers from inefficient charge transfer and ion transport kinetics due to weak turbulence and low electric intensity in flow electrodes,both restricted by the current ***,a new tip-array current collector(designated as T-CC)was developed to replace the conventional planar current collectors,which intensifies both the charge transfer and ion transport *** effects of tip arrays on flow and electric fields were studied by both computational simulations and electrochemical impedance spectroscopy,which revealed the reduction of ion transport barrier,charge transport barrier and internal *** the voltage increased from 1.0 to 1.5 and 2.0 V,the T-CC-based FCDI system(T-FCDI)exhibited average salt removal rates(ASRR)of 0.18,0.50,and 0.89μmol cm^(-2) min^(-1),respectively,which are 1.82,2.65,and 2.48 folds higher than that of the conventional serpentine current collectors,and 1.48,1.67,and 1.49 folds higher than that of the planar current ***,with the solid content in flow electrodes increased from 1 to 5 wt%,the ASRR for T-FCDI increased from 0.29 to 0.50μmol cm^(-2) min^(-1),which are 1.70 and 1.67 folds higher than that of the planar current ***,a salt removal efficiency of 99.89%was achieved with T-FCDI and the charge efficiency remained above 95%after 24 h of operation,thus showing its superior long-term stability.

关键词： Flow-electrode Capacitive deionization Current collector Tip effect Desalination

乳腺癌组织中 CC 类趋化因子5和重组人 S100钙结合蛋白 A4表达与临床病理特征及预后的关系

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中国基层医药 2017年第6期24卷 828-833页

作者：林雅章杰林义吴箐箐温岭市第一人民医院病理科浙江省温岭317500

目的：探讨乳腺癌组织中 CC 类趋化因子5（CCL5）和重组人 S100钙结合蛋白 A4（S100A4）表达与临床病理特征及预后的关系。方法利用免疫组化法检测40例正常乳腺组织和120例乳腺癌组织中CCL5和 S100A4的表达程度，并分析表达程度与乳腺... 详细信息

目的：探讨乳腺癌组织中 CC 类趋化因子5（CCL5）和重组人 S100钙结合蛋白 A4（S100A4）表达与临床病理特征及预后的关系。方法利用免疫组化法检测40例正常乳腺组织和120例乳腺癌组织中CCL5和 S100A4的表达程度，并分析表达程度与乳腺癌临床病理特征和预后的关系。结果乳腺癌组织中CCL5、S100A4表达阳性率分别为56．67％、62．50％，正常乳腺组织不表达，差异均有统计学意义（χ^2CCL5＝39．403，P ＜0．01；χ^2S100A4＝47．062，P ＜0．01）；CCL5在乳腺癌组织中的表达与临床分期（χ^2＝10．141，P ＜0．01）、病理类型（χ^2＝5．769，P ＝0．017）、淋巴结是否转移（χ^2＝34．178，P ＜0．01），差异均有统计学意义，而与患者年龄、肿瘤大小、病理分级差异均无统计学意义（均 P ＞0．05）；S100A4表达与患者临床分期（χ^2＝44．311，P ＜0．01）和淋巴结是否转移（χ^2＝14．843，P ＜0．01）差异均有统计学意义，与病理类型、年龄、肿瘤大小、病理分级差异均无统计学意义（均 P ＞0．05）；乳腺癌组织中 CCL5、S100A4表达呈正相关（r ＝0．301，P ＜0．01）；CCL5与乳腺癌复发呈正相关（OR ＝6．270，P ＜0．01），S100A4与乳腺癌复发无相关性（OR ＝1．103， P ＝0．768）；生存分析表明，CCL5表达阳性的患者无瘤生存时间显著短于 CCL5表达阴性的患者（χ^2＝11．851，P ＜0．01），S100A4表达阳性的患者无瘤生存时间显著短于 S100A4表达阴性的患者（χ^2＝5．433，P ＝0．021）；联合检测显示，CCL5阳性＋S100A4阳性组无瘤生存时间显著短于 CCL5阳性或 S100A4阳性组（χ^2＝15．341，P ＜0．01）和 CCL5阴性＋S100A4阴性组（χ^2＝15．341，P ＜0．01）。结论 CCL5和 S100A4在乳腺癌组织中的表达能够反映出癌组织转移、分期等情况，可用于乳腺癌临床病理特征和预后的判断。

关键词：乳腺肿瘤趋化因子CCL5 钙结合蛋白质类免疫组织化学

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海洋微藻多不饱和脂肪酸研究进展

福建水产 2013年第1期35卷 78-82页

作者：林武杰吴云辉厦门海洋职业技术学院福建厦门361012

多不饱和脂肪酸在人和动物的生理活动中具有重要的作用。海洋微藻中富含多不饱和脂肪酸。因此,利用海洋微藻生产多不饱和脂肪酸具有广阔的前景。本文综述了温度、光辐射、培养液的化学组成、通气量、存贮和培养方式等环境影响因子对海... 详细信息

多不饱和脂肪酸在人和动物的生理活动中具有重要的作用。海洋微藻中富含多不饱和脂肪酸。因此,利用海洋微藻生产多不饱和脂肪酸具有广阔的前景。本文综述了温度、光辐射、培养液的化学组成、通气量、存贮和培养方式等环境影响因子对海洋微藻中多不饱和脂肪酸含量的影响,以及利用光生物反应器培养微藻的现状,为后续的研究奠定了理论基础。

关键词：海洋微藻多不饱和脂肪酸光生物反应器

“Zero‑Strain” NiNb_(2)O_(6) Fibers for All‑Climate Lithium Storage

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Nano-Micro Letters 2025年第1期17卷 348-360页

作者： Yan Zhao Qiang Yuan Liting Yang Guisheng Liang Yifeng Cheng Limin wu Chunfu lin Renchao Che College of Physics Donghua UniversityShanghai 201620People’s Republic of China School of Materials Science and Engineering Institute of Materials for Energy and EnvironmentQingdao UniversityQingdao 266071People’s Republic of China Laboratory of Advanced Materials Shanghai Key Laboratory of Molecular Catalysis and Innovative MaterialsAcademy for Engineering&TechnologyFudan UniversityShanghai 200438People’s Republic of China Zhejiang Laboratory Hangzhou 311100People’s Republic of China Inner Mongolia University Hohhot 010021People’s Republic of China

Niobates are promising all-climate Li^(+)-storage anode material due to their fast charge transport,large specific capacities,and resistance to electrolyte ***,their moderate unit-cellvolume expansion(generally 5%–10%)during Li^(+)storage causes unsatisfactory long-term ***,“zero-strain”NiNb_(2)O_(6) fibers are explored as a new anode material with comprehensively good electrochemical *** Li^(+)storage,the expansion of electrochemical inactive NiO_(6) octahedra almost fully offsets the shrinkage of active NbO_(6) octahedra through reversible O *** superior volume-accommodation capability of the NiO_(6) layers guarantees the“zero-strain”behavior of NiNb_(2)O_(6) in a broad temperature range(0.53%//0.51%//0.74%at 25//−10//60℃),leading to the excellent cyclability of the NiNb_(2)O_(6) fibers(92.8%//99.2%//91.1%capacity retention after 1000//2000//1000 cycles at 10C and 25//−10//60℃).This NiNb_(2)O_(6) material further exhibits a large reversible capacity(300//184//318 mAh g−1 at 0.1C and 25//−10//60℃)and outstanding rate performance(10 to 0.5C capacity percentage of 64.3%//50.0%//65.4%at 25//−10//60℃).Therefore,the NiNb_(2)O_(6) fibers are especially suitable for large-capacity,fast-charging,long-life,and all-climate lithium-ion batteries.

关键词： NiNb_(2)O_(6)porous fiber “Zero-strain”mechanism Electrochemical property Harsh-temperature operation Operando characterization

Catalyst–Support Interaction in Polyaniline‑Supported Ni_(3)Fe Oxide to Boost Oxygen Evolution Activities for Rechargeable Zn‑Air Batteries

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Nano-Micro Letters 2025年第1期17卷 176-190页

作者： Xiaohong Zou Qian Lu Mingcong Tang jie wu Kouer Zhang Wenzhi Li Yunxia Hu Xiaomin Xu Xiao Zhang Zongping Shao Liang An Department of Mechanical Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment TechnologySchool of Environmental Science and TechnologyNanjing University of Information Science and TechnologyNanjing 210044People’s Republic of China Department of Chemistry The Chinese University of Hong KongMa Lin BuildingShatinHong Kong SAR 999077People’s Republic of China WA School of Mines:Minerals Energy and Chemical Engineering(WASM‑MECE)Curtin UniversityPerthWA 6102Australia Research Institute for Advanced Manufacturing The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China Research Institute for Smart Energy The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China

Catalyst–support interaction plays a crucial role in improving the catalytic activity of oxygen evolution reaction(OER).Here we modulate the catalyst–support interaction in polyaniline-supported Ni_(3)Fe oxide(Ni_(3)Fe oxide/PANI)with a robust hetero-interface,which significantly improves oxygen evolution activities with an overpotential of 270 mV at 10 mA cm^(-2)and specific activity of 2.08 mA cm_(ECSA)^(-2)at overpotential of 300 mV,3.84-fold that of Ni_(3)Fe *** is revealed that the catalyst–support interaction between Ni_(3)Fe oxide and PANI support enhances the Ni–O covalency via the interfacial Ni–N bond,thus promoting the charge and mass transfer on Ni_(3)Fe *** the excellent activity and stability,rechargeable Zn-air batteries with optimum Ni_(3)Fe oxide/PANI are assembled,delivering a low charge voltage of 1.95 V to cycle for 400 h at 10 mA cm^(-2).The regulation of the effect of catalyst–support interaction on catalytic activity provides new possibilities for the future design of highly efficient OER catalysts.

关键词： Catalyst-support interaction Supported catalysts Heterointerface Oxygen evolution reaction Zn-air batteries