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Flexible Graphene Field‑Effect Transistors and Their Application in Flexible Biomedical Sensing

Nano-Micro Letters 2025年第2期17卷 252-313页

作者： Mingyuan Sun Shuai wang Yanbo Liang Chao wang Yunhong Zhang hong Liu Yu Zhang lin Han Institute of Marine Science and Technology Shandong UniversityQingdao 266237ShandongPeople’s Republic of China State Key Laboratory of Crystal Materials Shandong UniversityJinan 250100ShandongPeople’s Republic of China School of Integrated Circuits Shandong UniversityJinan 250100ShandongPeople’s Republic of China Shandong Engineering Research Center of Biomarker and Artificial Intelligence Application Jinan250100ShandongPeople’s Republic of China

Flexible electronics are transforming our lives by making daily activities more *** to this innovation are field-effect transistors(FETs),valued for their efficient signal processing,nanoscale fabrication,low-power consumption,fast response times,and ***,known for its exceptional mechanical properties,high electron mobility,and biocompatibility,is an ideal material for FET channels and *** combination of graphene and FETs has given rise to flexible graphene field-effect transistors(FGFETs),driving significant advances in flexible electronics and sparked a strong interest in flexible biomedical ***,we first provide a brief overview of the basic structure,operating mechanism,and evaluation parameters of FGFETs,and delve into their material selection and patterning *** ability of FGFETs to sense strains and biomolecular charges opens up diverse application *** specifically analyze the latest strategies for integrating FGFETs into wearable and implantable flexible biomedical sensors,focusing on the key aspects of constructing high-quality flexible biomedical ***,we discuss the current challenges and prospects of FGFETs and their applications in biomedical *** review will provide valuable insights and inspiration for ongoing research to improve the quality of FGFETs and broaden their application prospects in flexible biomedical sensing.

关键词： Flexible Graphene Field-effect transistor Wearable Implantable Biosensor

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公路交叉口照明和限速对视觉搜索能力的影响

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吉林大学学报（工学版） 2023年第8期53卷 2287-2297页

作者：李洪涛王琳虹李俊达吉林大学交通学院长春130022 中汽研软件测评(天津)有限公司天津300300

为解决夜间车辆在村镇无信号公路交叉口易与自行车或行人碰撞的问题,基于注意分配理论将驾驶人视野图片亮度、凝视点分布面积、注视点一次马尔可夫平稳分布和累计注视时间作为评价指标,结合Logistics回归构建视觉搜索能力量化模型。设... 详细信息

为解决夜间车辆在村镇无信号公路交叉口易与自行车或行人碰撞的问题,基于注意分配理论将驾驶人视野图片亮度、凝视点分布面积、注视点一次马尔可夫平稳分布和累计注视时间作为评价指标,结合Logistics回归构建视觉搜索能力量化模型。设计模拟驾驶试验,采集6种车速和4种照明下的数据验证模型,结果表明模型的正确分类百分比为93.45%。不同照明限速方案的对比结果表明,夜间村镇附近公路交叉口段限速应设为50 km/h,路面平均照度应不低于10 lx。

关键词：交通运输系统工程视觉认知特性注意分配理论环境照明夜间最高限速视觉搜索能力

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Burden of nutritional deficiencies among children and adolescents aged 0 to 19 years in China,1990 to 2015

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Chinese Medical Journal 2021年第24期134卷 3012-3014页

作者： Yuan-Yuan Xu Xin-Ying Zeng Xiu Qiu Li-Wen Fang Zhuo-Qun wang Mai-Geng Zhou lin-hong wang National Center for Chronic and Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijing 100050China National Center for Women and Children’s Health Chinese Center for Disease Control and PreventionBeijing 100081China Guangzhou Women and Children’s Medical Center GuangzhouGuangdong 510623China

To the Editor:Nutritional deficiency is one of the major public health concerns in low-and middle-income *** and adolescents are particularly vulnerable to nutritional deficiencies due to their rapid growth and development *** 2015,nutritional deficiency was one of the top ten global causes of years lived with disability(YLDs)among children and adolescents in 195 countries and territories.[1]Nutritional deficiencies may have irreversible effects on the physical and cognitive development of children and adolescents,which may result in higher morbidity and mortality,and decreased productivity later in *** deficiencies are one of the major health concerns among children and adolescents in *** 2010,the deaths of Chinese children 0 to 14 years of age caused by nutritional deficiencies accounted for about 11.46%of total deaths in Chinese residents due to nutritional deficiencies.[2]Under-standing the disease burden of nutritional deficiencies among children and adolescents in the whole country is helpful for effective disease control and prevention,which may promote improving the health for all in the future.

关键词： income nutritional prevention

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Tackling China＇s Noncommunicable Diseases： Shared Origins, Costly Consequences and the Need for Actior

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Chinese Medical Journal 2015年第6期128卷 839-843页

作者： Yan Min Li-Xin Jiang Li-Jing L Yan lin-hong wang Sanjay Basu Yang-Feng Wu Randall S Stafford Wellness Living Laboratory Stanford Prevention Research Center Stanford University School of Medicine Stanford CA 94305-5411 USA China's National Centre for Cardiovascular Diseases Fuwai Hospital Beijing 100037 China Global Health Research Center Duke Kunshan University Kunshan Jiangsu 215316 China The George Institute for Global Health Peking University Health Science Center Beijing 100088 China National Center for Chronic and Non-communicable Disease Control and Prevention Chinese Center for Disease Control and Prevention Beijing 100050 China

Noncommunicable diseases （NCDs） have become the leading causes of death worldwide. As a concerning example, China＇s NCD prevalence is accelerating. As elsewhere, hypertension, diabetes, heart diseases, stroke, and obesity are the major contributors to this increasing trend. A common set of preceding risk factors is responsible for these different conditions, including physical inactivity, unhealthy eating habits, altered patterns of sleep, environmental pollution, and tobacco and alcohol abuse.

关键词： Non-communicable Diseases China Prevention Translational Research Policy Implications

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低FODMAP饮食与肠易激综合征

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胃肠病学 2016年第9期21卷 557-560页

作者：林鸿王承党福建医科大学附属第一医院消化内科福建医科大学消化系病研究室 350005

约60%肠易激综合征(IBS)患者的症状发作受饮食影响,饮食干预是IBS治疗策略的重要组成部分,如限制摄入可发酵的低聚糖、双糖、单糖和多元醇(FODMAP)。低FODMAP饮食疗法可减轻IBS症状,但具体疗效和长期低FODMAP饮食对健康的潜在影响尚需... 详细信息

约60%肠易激综合征(IBS)患者的症状发作受饮食影响,饮食干预是IBS治疗策略的重要组成部分,如限制摄入可发酵的低聚糖、双糖、单糖和多元醇(FODMAP)。低FODMAP饮食疗法可减轻IBS症状,但具体疗效和长期低FODMAP饮食对健康的潜在影响尚需进一步观察。本文就近年低FODMAP饮食与IBS的关系作一综述。

关键词：肠易激综合征饮食可发酵的短链碳水化合物

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Boosting bidirectional sulfur conversion enabled by introducing boron-doped atoms and phosphorus vacancies in Ni2P for lithium-sulfur batteries

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Journal of Energy Chemistry 2025年第1期100卷 760-769页

作者： lin Peng Yu Bai Hang Li Meixiu Qu Zhenhua wang Kening Sun Advanced Research Institute of Multidisciplinary Science Beijing Institute of Technology Beijing Key Laboratory of Chemical Power Source and Green Catalysis School of Chemistry and Chemical Engineering Beijing Institute of Technology

Lithium-sulfur （Li-S） batteries have gained great attention due to the high theoretical energy density and low cost,yet their further commercialization has been obstructed by the notorious shuttle effect and sluggish redox ***,we supply a strategy to optimize the electron structure of Ni2P by concurrently introducing B-doped atoms and P vacancies in Ni2P （Vp-B-Ni2P）,thereby enhancing the bidirectional sulfur *** study indicates that the simultaneous introduction of B-doped atoms and P vacancies in Ni2P causes the redistribution of electron around Ni atoms,bringing about the upward shift of d-band center of Ni atoms and effective d-p orbital hybridization between Ni atoms and sulfur species,thus strengthening the chemical anchoring for lithium polysulfides （LiPSs） as well as expediting the bidirectional conversion kinetics of sulfur ***,theoretical calculations reveal that the incorporation of B-doped atoms and P vacancies in Ni2P selectively promotes Li2S dissolution and nucleation ***,the Li-S batteries with Vp-B-Ni2P-separators present outstanding rate ability of 777 m A h g-1at 5 C and high areal capacity of 8.03 mA h cm-2under E/S of 5μL mg-1and sulfur loading of 7.20 mg *** work elucidates that introducing heteroatom and vacancy in metal phosphide collaboratively regulates the electron structure to accelerate bidirectional sulfur conversion.

关键词： Lithium sulfur batteries

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Pyroptosis,ferroptosis,and autophagy in spinal cord injury:regulatory mechanisms and therapeutic targets

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Neural Regeneration Research 2025年第10期20卷 2787-2806页

作者： Qingcong Zheng Du wang Rongjie lin Weihong Xu Department of Spinal Surgery the First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian ProvinceChina Arthritis Clinical and Research Center Peking University People’s HospitalBeijingChina Department of Orthopedic Surgery Fujian Medical University Union HospitalFuzhouFujian ProvinceChina

Regulated cell death is a form of cell death that is actively controlled by *** studies have shown that regulated cell death plays a key role after spinal cord *** and ferroptosis are newly discovered types of regulated cell deaths that have been shown to exacerbate inflammation and lead to cell death in damaged spinal ***,a complex form of cell death that is interconnected with various regulated cell death mechanisms,has garnered significant attention in the study of spinal cord *** injury triggers not only cell death but also cellular survival *** signaling pathways play pivotal roles in influencing the processes of both deterioration and repair in spinal cord injury by regulating pyroptosis,ferroptosis,and ***,this review aims to comprehensively examine the mechanisms underlying regulated cell deaths,the signaling pathways that modulate these mechanisms,and the potential therapeutic targets for spinal cord *** analysis suggests that targeting the common regulatory signaling pathways of different regulated cell deaths could be a promising strategy to promote cell survival and enhance the repair of spinal cord ***,a holistic approach that incorporates multiple regulated cell deaths and their regulatory pathways presents a promising multi-target therapeutic strategy for the management of spinal cord injury.

关键词： autophagy cell death ferroptosis inflammation pathological mechanisms pyroptosis regulated cell death regulatory pathways spinal cord injury therapeutic targets

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CaH2-promoted activity of Ni-carbonate interface for CO2 methanation

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Journal of Energy Chemistry 2025年第1期100卷 522-532页

作者： Jin-Peng wang Guo-Cui Mao Hui-lin Jiang Bao-Xia Dong Yun-Lei Teng School of Chemistry and Chemical Engineering Yangzhou University

Transition metal-carbonate interfaces often act as active sites in heterogeneous catalytic *** interface between transition metal and metal carbonate exhibits a dynamic equilibrium during the CO2hydrogenation reaction,involving surface carbonate hydrogenation and ***,there have been few reports on engineering the activity of the interface between transition metal and alkaline earth metal carbonate for catalytic *** work demonstrated that the incorporation of CaH2in Ni/CaCO3enhances the CO2methanation activity of the *** CO2conversion for Ni/CaH2-CaCO3reached 68.5%at 400°C,which was much higher than that of the Ni/CaCO3（31.6%） and Ni/CaH2-CaO （42.4%） ***,the Ni/CaH2-CaCO3catalysts remained stable during the stability test for 24 h at 400°C and 8 *** research revealed that CaH2played a crucial role in promoting the activity of the Ni-carbonate interface for ***2could modify the electronic structure of Ni and tune the structural properties of CaCO3to generate medium basic sites （OH groups）,which are favorable for the activation of H2and ***-situ Fourier transform infrared spectroscopy （FTIR） analysis combined with density functional theory calculations demonstrated that CO2activation occurs at the hydroxyl group （OH） on the CaH2-modified Ni-carbonate surface,leading to the formation of CO3H****,our study has confirmed that CO2methanation over the Ni/CaH2-CaCO3catalysts proceeds via the formate pathway.

关键词： Metal hydride Ni catalysts Carbonate Metal-carbonate interface

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中国四城市医院未婚人流女青年生殖道感染状况研究

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生殖与避孕 2005年第3期25卷 163-168页

作者：周敏张小松赵更力王临虹吴久玲北京大学第一医院妇产科妇儿保健中心北京100034 中国疾病预防控制中心妇幼保健中心北京100013

目的:了解未婚人流女青年生殖道感染/性传播疾病(RTIs/STIs)的患病率、性暴力的发生率及其相关的影响因素;了解未婚人流女青年性和生殖健康知识、态度、行为和生殖健康保健需求。方法:2002.10-2003.02期间,广东省深圳市、广西省南宁市... 详细信息

目的:了解未婚人流女青年生殖道感染/性传播疾病(RTIs/STIs)的患病率、性暴力的发生率及其相关的影响因素;了解未婚人流女青年性和生殖健康知识、态度、行为和生殖健康保健需求。方法:2002.10-2003.02期间,广东省深圳市、广西省南宁市、北京市、河南省郑州市的市级医院妇产科对2002名年龄<24岁来院要求人工流产的未婚女青年进行妇科检查和实验室检查及自填式问卷调查。结果:调查对象平均年龄为22.0±1.7岁,流动人口占61.0%。在调查中生殖道感染的患病率为57.1%,性传播疾病的患病率是9.8%。与生殖道感染有关的影响因素包括非流动人口、首次性行为年龄≤19岁、未使用避孕方法、既往有患RTIs病史、清洁外阴间隔时间≥2d。调查对象性暴力的发生率是11.7%。首次性行为的平均年龄为20.3±1.9岁。平均拥有性伴侣数为1.2±0.9个。生殖健康知识总分平均为4.2±2.3分(总分9分)。调查对象对生殖健康保健知识的需求依次为避孕知识、人工流产危害、性生理知识、性传播疾病的危害与预防等。结论:未婚人流女青年有关性和生殖健康知识贫乏;首次性行为平均年龄提前;RTIs/STIs是未婚人流女青年生殖健康的主要问题;未婚人流女青年中的性暴力现状不容忽视。

关键词：生殖健康生殖道感染性暴力未婚人流女青年

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罗汉果皂甙的含量测定

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天然产物研究与开发 2001年第2期13卷 36-40页

作者：高山林汪红中国药科大学南京210038

从罗汉果中提取强甜味剂罗汉果皂甙 ,并进行了初步分离 ,以香草醛高氯酸比色法测定了大中小三种罗汉果中总皂甙的含量 ,经方差分析 ,大、中罗汉果总皂甙含量无显著差异 ,而小果皂甙含量大于大、中果 ,提取单位皂甙所需原材料价格以小... 详细信息

从罗汉果中提取强甜味剂罗汉果皂甙 ,并进行了初步分离 ,以香草醛高氯酸比色法测定了大中小三种罗汉果中总皂甙的含量 ,经方差分析 ,大、中罗汉果总皂甙含量无显著差异 ,而小果皂甙含量大于大、中果 ,提取单位皂甙所需原材料价格以小果为低。若将其作为甜味剂开发使用 ,以小果最为经济。为开发利用商品性差、价格低的小果 ,提供了实验研究依据和开发利用途径。

关键词：罗汉果三萜皂甙含量测定药用植物果实大小质量

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