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Journal of Iron and Steel Research International 2024年第1期31卷 215-223页

作者： Cheng Lu wan-lin wang Chen-yang Zhu Jie Zeng Xin-yuan Liu Hua-long Li School of Metallurgy and Environment Central South UniversityChangsha410083HunanChina National Center for International Research of Clean Metallurgy Central South UniversityChangsha410083HunanChina Institute of Research of Iron and Steel ShasteelZhangjiagang215625JiangsuChina

Typical Q235 low-carbon steel samples with different hydrogen contents(0.0004,0.0008,and 0.0013 wt.%)were prepared by adjusting the environment humidity and *** effects of hydrogen on interfacial heat transfer,contact behavior,and microstructure evolution were investigated using a novel droplet solidification *** results revealed that when the hydrogen content increases from 0.0004 to 0.0013 wt.%,the maximum heat flux between the molten steel and cooling substrate decreases from 8.01 to 6.19 MW/m^(2),and the total heat removed in the initial 2 s reduces from 10.30 to 8.27 MJ/m^(2).Moreover,the final contact angle between the molten steel and substrate increases from 103.741°to 113.697°,and the number of pores on the droplet bottom surface increases significantly from 21 to 210 with the increase in *** surface roughness of the droplet bottom surface increases from 20.902 to 49.181 *** addition,the average grain size of the droplet increases from 14.778 to 33.548 pm with the increase in the hydrogen *** interfacial contact condition becomes worse due to the escape of hydrogen from the steel matrix during the cooling process,which leads to the reduction in the interfacial heat transfer and the increase in the grain size.

关键词： Strip casting Hydrogen content Interfacial heat transfer behavior Contact behavior Microstructure evolution

RIOK1 synergizes with TRIP13 by regulating the E2F-Rb signaling pathway to promote the proliferation of esophageal cancer cells

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Genes & Diseases 2024年第3期11卷 55-58页

作者： Chengyu Li Deyuan Pan wan lin Danxia Deng Yingxin Zhou Hui Zhao Feng Pan Liyan Xu Enmin Li lin Long The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area Department of Biochemistry and Molecular BiologyShantou University Medical CollegeShantouGuangdong 515041China Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology Institute of Oncologic PathologyShantou University Medical CollegeShantouGuangdong 515041China Institute of Basic Medical Science Cancer Research CenterShantou University Medical CollegeShantouGuangdong 515041China Clinical Research Center Shantou Central HospitalShantouGuangdong 515041China

Esophageal cancer is one of the leading causes of cancer death in the world,with approximately half of the new cases occurring in China every year.^(1)Esophageal squamous cell carcinoma(ESCC)is the main subtype,accounting for more than 90%,and the five-year survival rate is less than 10%.Using large-scale genome analysis,many driver mutations and key pathways associated with ESCC have been ***,these genomic signatures have not improved the clinical management of EscC patients,or established effective targeted therapy.^(2)Esophageal cancer still lacks representative molecular markers.

关键词： cancer esophageal Esophageal

Metabolomic Analysis in Saliva and Different Brain Regions of Older Mice with Postoperative Delirium Behaviors

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Biomedical and Environmental Sciences 2024年第2期37卷 133-145页

作者： LIU Xiao CAO Ying lin Xiao wan GAO Dan Yang MIAO Hui Hui LI Tian Zuo Department of Anesthesiology Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China

Objective Postoperative delirium(POD)has become a critical challenge with severe consequences and increased incidences as the global population ***,the underlying mechanism is yet *** study aimed to explore the changes in metabolites in three specific brain regions and saliva of older mice with postoperative delirium behavior and to identify potential non-invasive *** Eighteen-month-old male C57/BL6 mice were randomly assigned to the anesthesia/surgery or control *** tests were conducted 24 h before surgery and 6,9,and 24 h after *** C3(C3)and S100 calcium-binding protein B protein(S100beta)levels were measured in the hippocampus,and a metabolomics analysis was performed on saliva,hippocampus,cortex,and amygdala *** In total,43,33,38,and 14 differential metabolites were detected in the saliva,hippocampus,cortex,and amygdala,respectively.“Pyruvate”“alpha-linolenic acid”and“2-oleoyl-1-palmitoy-snglycero-3-phosphocholine”are enriched in one common pathway and may be potential non-invasive biomarkers for *** changes were observed in the three brain regions,with the upregulation of 1-methylhistidine and downregulation of *** Dysfunctions in energy metabolism,oxidative stress,and neurotransmitter dysregulation are implicated in the development of *** identification of changes in the level of salivary metabolite biomarkers could aid in the development of noninvasive diagnostic methods for POD.

关键词： Metabolomic Postoperative delirium(POD) Mechanism Biological marker

Large Deviations for a Critical Galton-Watson Branching Process

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Acta Mathematicae Applicatae Sinica 2024年

作者： Dou-dou LI wan-lin SHI Mei ZHANG College of Statistics and Data Science Faculty of Science Beijing University of Technology Laboratory of Mathematics and Complex Systems (Ministry of Education) School of Mathematical SciencesBeijing Normal University Department of Mathematics and Physics North China Electric Power University

In this paper, a critical Galton-Watson branching process{Zn}is considered. Large deviation rates of SZn:=∑i=1ZnXiare obtained, where{Xi, i≥1}is a sequence of independent and identically distributed random variables and X1is in the domain of attraction of an α-stable law with α∈(0, 2). One shall see that the convergence rate is determined by the tail index of X1and the variance of Z1. Our results can be compared with those ones of the supercritical case.

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Research progress on the effect of pyroptosis on the occurrence,development,invasion and metastasis of colorectal cancer

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3410-3427页

作者： Xu wang Qi-Hang Yin lin-Lu wan Ruo-Lan Sun Gang wang Jun-Fei Gu De-Cai Tang School of Traditional Chinese Medicine Nanjing University of Chinese MedicineNanjing 210023Jiangsu ProvinceChina Department of Ana and Intestine Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina

Pyroptosis is a type of programmed cell death mediated by gasdermines(GSDMs).The N-terminal domain of GSDMs forms pores in the plasma membrane,causing cell membrane rupture and the release of cell contents,leading to an inflammatory response and mediating *** plays an important role in inflammatory diseases and malignant *** the further study of pyroptosis,an increasing number of studies have shown that the pyroptosis pathway can regulate the tumor microenvironment and antitumor immunity of colorectal cancer and is closely related to the occurrence,development,treatment and prognosis of colorectal *** review aimed to explore the molecular mechanism of pyroptosis and the role of pyroptosis in the occurrence,development,treatment and prognosis of colorectal cancer(CRC)and to provide ideas for the clinical diagnosis and treatment of CRC.

关键词： Cell pyroptosis Tumor metastasis Colorectal cancer Clinical diagnosis Review

Sirolimus can promote the disappearance of renal angiomyolipoma associated with tuberous sclerosis complex:a prospective cohort study

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World Journal of Pediatrics 2024年第6期20卷 602-610页

作者： Shuo Dun Yang-Yang wang lin wan Qiu-Hong wang Qian Lu Xiao-Yan Yang Qi Zhang Hui-Min Chen Lu-Peng Qiu Li-Ping Zou Medical School of Chinese PLA Beijing 100853China Department of Pediatrics The First Medical CenterChinese PLA General HospitalBeijing 100853China Center of Epilepsy Beijing Institute for Brain DisordersBeijing 100069China

Background Renal angiomyolipoma(RAML)is the most common kidney lesion in patients with tuberous sclerosis complex(TSC),affecting about 80%of *** is a benign tumor that grows over time,usually bilaterally,and can easily lead to kidney complications such as acute ***,we investigated the efficacy and safety of sirolimus in children with TSC-associated RAML and explored the factors affecting tumor disappearance under sirolimus treatment through subgroup *** A prospective cohort study was *** was initiated at 1 mg/(m^(2)×day),and dose adjustments were made by a 2-week titration period to attain a trough blood concentration of 5-10 ng/*** disappearance of RAML in chil-dren after sirolimus treatment was observed,and Cox regression was used to screen the factors affecting tumor *** One hundred and twenty-six patients who met the criteria were *** 3 months,6 months,12 months,and 24 months of follow-up,tumors disappeared in 18(14.3%),30(23.8%),39(31.0%),and 42(33.3%)children,*** disappeared in 50(39.7%)children by the last visit of each individual,and 30(60%)of them occurred within 6 *** multivariate Cox regression analysis showed that patients with a smaller maximum tumor diameter at baseline had a higher tumor disappearance ***-six(29%)patients had stomatitis during the entire treatment period,and no serious *** Sirolimus could promote the disappearance of TSC-related *** disappearance rate was correlated with the maximum diameter at baseline,and the smaller the tumor was,the higher the disappearance *** is well tolerated in the treatment of RAML associated with TSC.

关键词： Angiomyolipoma mTOR inhibitor Sirolimus Tuberous sclerosis

基于矩阵乘积压缩态的动态可扩展秘密共享方案

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物理学报 2024年第18期73卷 24-37页

作者：赖红万林春西南大学计算机与信息科学学院重庆400715

目前,基于纠缠态的量子秘密共享(quantum secret sharing,QSS)方案未充分利用纠缠态的概率振幅潜力.然而,纠缠态的概率振幅是量子信息学的一个关键特性,在量子计算和量子通信等领域有着广泛的应用潜力.值得注意的是,纠缠态可以通过矩阵... 详细信息

目前,基于纠缠态的量子秘密共享(quantum secret sharing,QSS)方案未充分利用纠缠态的概率振幅潜力.然而,纠缠态的概率振幅是量子信息学的一个关键特性,在量子计算和量子通信等领域有着广泛的应用潜力.值得注意的是,纠缠态可以通过矩阵乘积态(matrix product state,MPS)有效表达.利用MPS对纠缠态进行表征,能够准确地揭示与概率振幅相关的纠缠特性.本研究证明利用MPS表征纠缠态,可以将一个W态压缩为一个单光子和一个矩阵,展示一种新的技术路径.此外,本研究还提出MPS与秘密共享方案之间的创新互操作性,即通过压缩允许量子份额与共享的量子态之间形成非一对一的映射关系.这种方法可能提供一种更高效的方式来实现量子信息的编码和传输,对于量子秘密共享尤为重要.同时,我们提出的QSS方案具有动态特性,能够根据需要轻松地添加或移除参与者,以更好地适应参与者需求的变化,并在实际应用场景中展现出更高的实用性和适应性.本文的方案能够在保持高效纠缠利用的同时,满足系统的多元需求,包括但不限于通信安全性、数据传输率和系统的可扩展性.

关键词：矩阵乘积压缩态纠缠态的概率振幅可扩展性动态性

大学生运动身份认同对运动行为的影响:有调节的中介模型

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中国临床心理学杂志 2024年第2期32卷 463-468,415页

作者：任怡霖李宛霖朱风书扬州大学体育学院扬州225127

目的:探讨大学生运动身份认同与运动行为的关系,重点关注内部动机的中介作用,以及体重认知偏差的调节作用。方法:采用体育运动等级量表、运动依赖量表、运动身份认同量表、内部动机量表以及体重认知偏差问卷,对江苏省某高校950名在校大... 详细信息

目的:探讨大学生运动身份认同与运动行为的关系,重点关注内部动机的中介作用,以及体重认知偏差的调节作用。方法:采用体育运动等级量表、运动依赖量表、运动身份认同量表、内部动机量表以及体重认知偏差问卷,对江苏省某高校950名在校大学生进行调查,剔除59份无效问卷,最终获得有效问卷891份。结果:(1)大学生运动身份认同与适应性及适应不良运动行为呈正相关;(2)内部动机在大学生运动身份认同与适应性及适应不良运动行为之间起部分中介作用。体重认知偏差在运动身份认同和内部动机与运动行为(适应性及适应不良运动行为)关系间起调节作用。结论:运动身份认同不仅直接影响大学生运动行为,还可以通过内部动机间接地影响其运动行为。体重认知偏差调节大学生运动身份认同和内部动机与运动行为的关系。

关键词：运动身份认同体重认知偏差内部动机运动行为

地理大数据揭示中国主要城市建成环境物质存量的空间格局

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Engineering 2024年第3期34卷 143-153页

作者： Zhou Huang Yi Bao Ruichang Mao Han wang Ganmin Yin lin wan Houji Qi Qiaoxuan Li Hongzhao Tang Qiance Liu linna Li Bailang Yu Qinghua Guo Yu Liu Huadong Guo Gang Liu Institute of Remote Sensing and Geographical Information Systems School of Earth and Space SciencesPeking UniversityBeijing 100871China International Research Center of Big Data for Sustainable Development Goals Beijing 100094China SDU Life Cycle Engineering Department of Green TechnologyUniversity of Southern DenmarkOdense 5230Denmark Department of Construction Management School of Civil EngineeringTsinghua UniversityBeijing 100084China School of Computer Science China University of GeosciencesWuhan 430074China School of Geographical Sciences East China Normal UniversityShanghai 200062China Land Satellite Remote Sensing Application Center Ministry of Natural ResourcesBeijing 100048China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 100101China Department of Geography California State UniversityLong BeachCA 90840USA Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100094China College of Urban and Environmental Sciences Peking UniversityBeijing 100871China

The patterns of material accumulation in buildings and infrastructure accompanied by rapid urbanization offer an important,yet hitherto largely missing stock perspective for facilitating urban system engineering and informing urban resources,waste,and climate ***,our existing knowledge on the patterns of built environment stocks across and particularly within cities is limited,largely owing to the lack of sufficient high spatial resolution *** study leveraged multi-source big geodata,machine learning,and bottom-up stock accounting to characterize the built environment stocks of 50 cities in China at 500 m fine-grained *** per capita built environment stock of many cities(261 tonnes per capita on average)is close to that in western cities,despite considerable disparities across cities owing to their varying socioeconomic,geomorphology,and urban form *** is mainly owing to the construction boom and the building and infrastructure-driven economy of China in the past ***’s urban expansion tends to be more“vertical”(with high-rise buildings)than“horizontal”(with expanded road networks).It trades skylines for space,and reflects a concentration-dispersion-concentration pathway for spatialized built environment stocks development within cities in *** results shed light on future urbanization in developing cities,inform spatial planning,and support circular and low-carbon transitions in cities.

关键词： Urban system engineering Built environment stock Spatial pattern Urban sustainability Big geodata

土地革命战争时期中央革命根据地生态环境的保护与治理

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湘潭大学学报（哲学社会科学版） 2024年第5期48卷 129-133页

作者：宫婉琳罗玉明湘潭大学马克思主义学院湖南湘潭411105

土地革命战争时期是中国共产党开展生态环境保护与治理的起点。中央革命根据地建立后,由于水旱天灾的影响、战争的破坏、滥砍滥伐行为,根据地的生态环境遭到严重破坏。中国共产党充分认识到保护生态环境的重要性,首次提出“绿水青山”... 详细信息

土地革命战争时期是中国共产党开展生态环境保护与治理的起点。中央革命根据地建立后,由于水旱天灾的影响、战争的破坏、滥砍滥伐行为,根据地的生态环境遭到严重破坏。中国共产党充分认识到保护生态环境的重要性,首次提出“绿水青山”“水利是农业命脉”等思想,并采取措施,领导根据地人民开展植树造林、兴修水利运动,取得良好成绩,改善根据地生态环境质量,提高人民生活水平。这为今天生态文明建设提供了借鉴。

关键词：生态环境绿水青山保护与治理