检索结果-南通市图书馆

N-heterocyclic Carbenes Catalyzed Phospho-Aldol Reaction of Aldehydes

Chinese Journal of Chemistry 2013年第12期31卷 1573-1576页

作者： lin he zhihua cai xiaowei ma guangfen du Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan and School of Chemistry and Chemical Engineering Shihezi University Xinjiang 832000 China

An efficient phospho-aldol reaction of aldehydes catalyzed by N-heterocyclic carbenes （NHCs） has been developed. With 10 mol% stable NHC 1,3-bis（2,6-diisopropylphenyl）imidazol-2-ylidene, various aldehydes reacted with dialkylphosphites smoothly to provide a-hydroxy phosphonates in 59%--99% yield. In this process, NHC was assumed to function as a carbon-centered bronsted base.

关键词： N-heterocyclic carbenes phosphite aldehyde phospho-aldol reaction a-hydroxy phosphonate

来源：