检索结果-南通市图书馆

Simulation and Instability Investigation of the Flow around a Cylinder between Two Parallel Walls

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2015年第2期24卷 140-148页

作者： DOU hua-Shu BEN An-qing Faculty of Mechanical Engineering and Automation Zhejiang Sci-Tech University

The two-dimensional flows around a cylinder between two parallel walls at Re=40 and Re=100 are simulated with computational fluid dynamics(CFD). The governing equations are Navier-Stokes equations. They are discretized with finite volume method(FVM) and the solution is iterated with PISO Algorithm. Then, the calculating results are compared with the numerical results in literature, and good agreements are obtained. After that, the mechanism of the formation of Karman vortex street is investigated and the instability of the entire flow field is analyzed with the energy gradient theory. It is found that the two eddies attached at the rear of the cylinder have no effect on the flow instability for steady flow, i.e., they don't contribute to the formation of Karman vortex street. The formation of Karman vortex street originates from the combinations of the interaction of two shear layers at two lateral sides of the cylinder and the absolute instability in the cylinder wake. For the flow with Karman vortex street, the initial instability occurs at the region in a vortex downstream of the wake and the center of a vortex firstly loses its stability in a vortex. For pressure driven flow, it is confirmed that the inflection point on the time-averaged velocity profile leads to the instability. It is concluded that the energy gradient theory is potentially applicable to study the flow stability and to reveal the mechanism of turbulent transition.

关键词： numerical simulation cylinder energy gradient theory stability inflection point

Metabolic pathway modulation by olanzapine:Multitarget approach for treating violent aggression in patients with schizophrenia

在线全文

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2025年第1期15卷 37-53页

作者： Yan-Ning Song Shuang Xia Zhi Sun Yong-Chao Chen Lu Jiao Wen-hua Wan Hong-Wei Zhang Xiao Guo hua Guo Shou-Feng Jia Xiao-Xin Li Shi-Xian Cao Li-Bin Fu Meng-Meng Liu Tian Zhou Lv-Feng Zhang qing-Quan Jia Department of Pharmacy The Affiliated Encephalopathy Hospital of Zhengzhou University(Zhumadian Second People's Hospital)Zhumadian 463000Henan ProvinceChina Department of Pharmacy The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina Department of Pharmacy Zhumadian First People's HospitalZhumadian 463000Henan ProvinceChina Scientific Education Section The Affiliated Encephalopathy Hospital of Zhengzhou University(Zhumadian Second People's Hospital)Zhumadian 463000Henan ProvinceChina Department of Psychiatry The Affiliated Encephalopathy Hospital of Zhengzhou University(Zhumadian Second People's Hospital)Zhumadian 463000Henan ProvinceChina Clinical Laboratory The Affiliated Encephalopathy Hospital of Zhengzhou University(Zhumadian Second People's Hospital)Zhumadian 463000Henan ProvinceChina Publicity Division The Affiliated Encephalopathy Hospital of Zhengzhou University(Zhumadian Second People's Hospital)Zhumadian 463000Henan ProvinceChina

BACKGROUND The use of network pharmacology and blood metabolomics to study the patho-genesis of violent aggression in patients with schizophrenia and the related drug mechanisms of action provides new directions for reducing the risk of violent aggression and optimizing treatment *** To explore the metabolic regulatory mechanism of olanzapine in treating patients with schizophrenia with a moderate to high risk of violent *** Metabolomic technology was used to screen differentially abundant metabolites in patients with schizophrenia with a moderate to high risk of violent aggression before and after olanzapine treatment,and the related metabolic pathways were *** pharmacology was used to establish protein-protein interaction networks of the core targets of *** Ontology functional analysis and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis were subsequently *** Compared with the healthy group,the patients with schizophrenia group presented significant changes in the levels of 24 metabolites related to the disruption of 9 metabolic pathways,among which the key pathways were the alanine,aspartate and glutamate metabolism and arginine biosynthesis *** treatment with olanzapine,the levels of 10 differentially abundant metabolites were significantly reversed in patients with *** effectively regulated six metabolic pathways,among which the key pathways were alanine,aspartate and glutamate metabolism and arginine biosynthesis *** core targets of olanzapine were involved in several key *** The metabolic pathways of alanine,aspartate,and glutamate metabolism and arginine biosynthesis are the key pathways involved in olanzapine treatment for aggressive schizophrenia.

关键词： Schizophrenia Violent aggression Olanzapine Metabolomics Network pharmacology

The Community Abundance and Diversity of Arable Soil Insect Community Following Different Fertilizer Treatments in Xinjiang, China

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2008年第2期7卷 210-216页

作者： lin Ying-hua LIU hua ZHANG Shu-qing ZHANG Fu-dao Key Laboratory of Forest Protection State Forestry Administration/Research Institute of Ecology Environment and Protection Chinese Academy of Forestry Beijing 100091 P.R.China Institute of Soil and Fertilizer Xinjiang Academy of Agricuhural Sciences Urumqi 830000 P.R.China Institute of Agricuhural Resources and Regional Planning Chinese Academy of Agricultural Sciences Beijing 100081 P.R.China

The soil insect community was studied in grey desert soil district in September 2004. 90 soil samples and 100 pitfalls were collected from 10 treatments, i.e., abandonment （Aband.）, CK, N, NP, NK, PK, NPK, MNPK （fertilizer N：organic N = 3：7）, 1.5MNPK, and SNPK. 4915 soil insects （128 unknown）, as individuals belonging to 9 orders and 33 families, were obtained by pitfall traps and modified Tullgren methods. The results showed that, based on the number of individuals and groups, the macro fauna in total reached their peaks in abandonment, whereas meso and micro fauna in N and PK, respectively. Of the 10 treatments, the most dominant of soil insect composition was in MNPK and most evenness was N. The result by Kruskal-Wallis test indicated that the distribution of the arable soil insect was significantly impacted by different fertilizer treatments （X0.05（9） = 23.38, P 〈 0.005）, and soil insect group of the abandonment was significantly different from that of other fertilizer treatments. The soil insect community was divided into five groups by non-metric- MDS analysis：（1） NPK, MNPK, 1.5MNPK, CK, （2） NP and PK, （3） NK and N, （4） SNPK, and （5） abandonment, which indicated that distribution of soil insect was related to the character of the fertilizer. In the principal component analysis, two factors explained 98.51% of the total variation among the 10 treatments, and the factor one explained that N and SNPK positively affected soil insect community, whereas factor two explained that 1.5MNPK positively affected soil insect community, which showed that the diversified fertilizer did not evenly affect the soil insect community.

关键词： soil insect fertilizer non-metric multidimentional scaling (non-metric-MDS) principal component analysis(PCA)

Color routing at the nanoscale

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2019年第1期8卷 663-664页

作者： qing-hua Xu Department of Chemistry National University of Singapore3 Science Drive 3Singapore 117543Singapore

Two types of color routing effects were observed in silver nanorods on the single particle level as a result of distinct far-field behaviors of different multipolar plasmon modes,which enables tunable color sorting wi... 详细信息

关键词： routing nanorods silver

Torsional Response Analysis of Flexible Pipe Based on Theory and Finite Element Method

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Ocean Engineering 2023年第2期37卷 190-203页

作者： LEI qing-long ZHU Xiao-hua School of Mechanical Engineering Southwest Petroleum UniversityChengdu 610500China Oil and Gas Equipment Technology Sharing and Service Platform of Sichuan Province Chengdu 610500China

As key components connecting offshore floating production platforms and subsea imports, offshore flexible pipes play significant roles in oil, natural gas, and water injection. It is found that torsional failure is one of the failure modes of flexible pipes during transportation and laying. In this paper, a theoretical model(TM) of a flexible pipe section mechanics is established, in which the carcass layer and the pressure armor layer are equivalent to the orthogonal anisotropic layers due to its complex cross-section structure. The calculation results of the TM are consistent with those of a finite element model(FEM), which can accurately describe the torsional response of the flexible ***, the TM and FEM are used to discuss the influence of boundary conditions on the torsional *** structure of the flexible pipe is stable when twisted counterclockwise. However, limiting the top axial displacement can improve the axial and radial instability of the tensile armor layer when twisted clockwise. Finally, it is recommended that the flexible pipe can be kept under top fixation during service or installation to avoid torsional failure.

关键词： flexible pipe torsional response analytical model finite element model

兔源肺炎克雷伯氏菌和大肠埃希氏菌的分离鉴定及小鼠感染试验

在线全文

学校读者我要写书评

暂无评论

动物医学进展 2025年第1期46卷 55-61页

作者：张鲁星石晴晴陶梦珂李苗苗赵恒胡功政吴华刘建华河南农业大学动物医学院河南郑州450000

为确定某规模化兔场仔兔呼吸道感染合并腹泻引起死亡的原因,无菌采集病兔气管、肺、肝组织进行病毒和细菌检测。通过细菌分离培养、革兰氏染色、生化鉴定、16S rRNA序列同源性比对分析,确定分离菌株种属。通过药物敏感性试验、耐药基因... 详细信息

为确定某规模化兔场仔兔呼吸道感染合并腹泻引起死亡的原因,无菌采集病兔气管、肺、肝组织进行病毒和细菌检测。通过细菌分离培养、革兰氏染色、生化鉴定、16S rRNA序列同源性比对分析,确定分离菌株种属。通过药物敏感性试验、耐药基因检测及动物回归对分离菌株的耐药性和致病性进行分析。结果显示,病毒检测结果均为阴性;从同一只仔兔的肺脏、气管中分离得到2株肺炎克雷伯氏菌,分别将其命名为KF1、KQ2,从肝脏中分离得到1株大肠埃希氏菌并将其命名为EG3。药敏试验结果显示,菌株KF1、KQ2和EG3均对黏菌素和氨苄青霉素钠耐药,对阿米卡星和氟苯尼考敏感。3株菌均检出耐药基因mcr-1和bla TEM。动物致病性试验显示,KF1组小鼠5 h后死亡50%,24 h全部死亡;混合组小鼠12 h后全部死亡;KQ2和EG3组48 h全部死亡。以上研究表明,大肠埃希氏菌和肺炎克雷伯氏菌的混合感染是引起仔兔死亡的主要原因,3株分离株单独及混合感染均能引起试验小鼠死亡。

关键词：兔肺炎克雷伯氏菌大肠埃希氏菌分离鉴定耐药基因

2010—2016年安徽省某三甲医院手足口病监测分析

在线全文

学校读者我要写书评

暂无评论

中华全科医学 2018年第8期16卷 1250-1253页

作者：沈嬿周瑞林清华陆惠娟瞿芳蕾秦晓辉蚌埠医学院第一附属医院预防保健科安徽蚌埠233004

目的分析2010—2016年安徽省某三甲医院监测的手足口病的流行病学特征,为科学制定防控体系提供依据。方法数据来源于"中国疾病预防信息系统"中的"传染病报告信息管理系统",采用描述流行病学方法对数据进行分析,使用Excel整理数据,SPSS 2... 详细信息

目的分析2010—2016年安徽省某三甲医院监测的手足口病的流行病学特征,为科学制定防控体系提供依据。方法数据来源于"中国疾病预防信息系统"中的"传染病报告信息管理系统",采用描述流行病学方法对数据进行分析,使用Excel整理数据,SPSS 22.0统计软件进行统计学处理,采用χ~2检验。结果 2010—2016年共报告手足口病病例数5 731例,2010—2012年呈现逐年上升,2013—2016年呈现隔年增高的趋势。男女性别比为1.82∶1;发病人群多集中在3岁以下儿童(78.87%,4 520/5 731),各年度各年龄组发病人群分布差异有统计学意义(χ~2=92.415,P=0.018)。对各年度各年龄组发病人群趋势进行统计学处理,差异无统计学意义(χ~2_(趋势)=0.160,P=0.689)。发病人群以散居儿童为主(92.97%,5 328/5 731),各年次发病人群分布差异有统计学意义(χ~2=193.512,P<0.001),各年次发病人群分布趋势行统计学处理,差异无统计学意义(χ~2_(趋势)=2.546,P=0.111)。全年均有确诊病例上报,4—7月为发病高峰期(64.56%,3 700/5 731),呈现出明显的"单峰"规律,各年度各月份发病数差异有统计学意义(χ~2=826.958,P<0.001),对各年度各月份发病趋势行统计学处理,差异无统计学意义(χ~2_(趋势)=0.207,P=0.649)。报告人群多集中在本市市区及所辖三县(72.78%,4 171/5 731)。结论手足口病的流行呈现出隔年上升趋势,季节性明显,人群分布明确,应重视3岁以下散居儿童的健康教育,高危季节积极做好防控工作。

关键词：手足口病儿童流行病学

Realization of Bipartite Positive-Operator-Value Measurements of Two-Photon Polarization States

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2009年第2期51卷 244-246页

作者： lin qing College of Information Science and Engineering Huaqiao University Quanzhou 362021 China

In this letter, we propose a scheme of a special quantum optical Fredkin gate assisted by optical manip- ulations and postselection from the coincidence measurements, and then modify it with cross-Kerr nonlinearities to be suitable for the realization of all possible positive operator-valued measurements of bipartite polarization states. This scheme is feasible in the lab with the current experimental technology.

关键词： POVM linear optics cross-Kerr nonlinearity

L型钙通道阻滞剂和康复运动对冠心病患者血压和血脂状况的影响

在线全文

学校读者我要写书评

暂无评论

体育科学 2015年第6期35卷 45-48,56页

作者：刘洵赵婉婷石晓明谭思洁林青华李淑荣王一春刘博淼天津体育学院健康与运动科学系天津300381 北京军区天津疗养院中医针灸康复科天津300000

目的:探讨L型钙通道阻滞剂和康复运动对冠心病患者血压和血脂状况的影响。方法:13名服用L型钙通道阻滞剂的女性冠心病患者(服药组),17名不服用L型钙通道阻滞剂的女性冠心病患者(未服药组)为本研究的受试者,在康复程序前、后,对她们进行... 详细信息

目的:探讨L型钙通道阻滞剂和康复运动对冠心病患者血压和血脂状况的影响。方法:13名服用L型钙通道阻滞剂的女性冠心病患者(服药组),17名不服用L型钙通道阻滞剂的女性冠心病患者(未服药组)为本研究的受试者,在康复程序前、后,对她们进行了收缩压(SBP)、舒张压(DBP)、心率(HR)、心率血压乘积(RPP)、血清胆固醇(CHO)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL)和低密度脂蛋白胆固醇(LDL)的测定。结果:1)药物的影响:运动康复程序前,服药组的收缩压和舒张压与未服药组已无显著差异(P>0.05),但其心率显著低于未服药组(P0.05)。2)运动的影响:运动康复程序后,未服药组的SBP、HR、RPP和CHO出现了显著的下降(P<0.05和P<0.01)。3)药物与运动的共同影响:运动康复程序后,服药组不仅胆固醇浓度显著下降(P<0.05),而且TG和HDL也有了显著的改善(P<0.05)。结论:适宜的运动对改善冠心病患者的血压、血脂和心肌的耗氧状况有积极的作用;与单纯运动相比,L型钙通道阻滞剂与运动的共同作用对血脂的影响则更为明显。

关键词：冠心病患者运动康复程序 L型钙通道阻滞剂血压血脂