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Effects of repetitive transcranial magnetic stimulation on cognitive function and cholinergic activity in the rat hippocampus after vascular dementia

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Neural Regeneration Research 2018年第8期13卷 1384-1389页

作者： Xiao-Qiao Zhang li li Jiang-Tao Huo Min Cheng lin-hong li Department of General Medicine & Neurology Taihe Hospital Hubei University of Medicine Department of Pharmacy Taihe Hospital Hubei University of Medicine

Repetitive transcranial magnetic stimulation （rTMS） is a non-invasive treatment that can enhance the recovery of neurological function after stroke. Whether it can similarly promote the recovery of cognitive function after vascular dementia remains unknown, In this study, a rat model for vascular dementia was established by the two-vessel occlusion method. Two days after injury, 30 pulses of rTMS were ad- ministered to each cerebral hemisphere at a frequency of 0.5 Hz and a magnetic field intensity of 1,33 T. The Morris water maze test was used to evaluate learning and memory function. The Karnovsky-Roots method was performed to determine the density of cholinergic neurons in the hippocampal CA1 region. Immunohistochemical staining was used to determine the number of brain-derived neurotroph- ic factor （BDNF）-immunoreactive cells in the hippocampal CA1 region, rTMS treatment for 30 days significantly improved learning and memory function, increased acetylcholinesterase and choline acetyltransferase activity, increased the density of cholinergic neurons, and increased the number of BDNF-immunoreactive cells. These results indicate that rTMS can ameliorate learning and memory deficiencies in rats with vascular dementia, The mechanism through which this occurs might be related to the promotion of BDNF expression and subsequent restoration of cholinergic system activity in hippocampal CA 1 region.

关键词： nerve regeneration cholinergic system neurotrophic factor hippocampal CA1 region learning and memory function repetitivetranscranial magnetic stimulation vascular dementia neural regeneration

Transferring a Multi-atom Entangled State via Adiabatic Passage

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Communications in Theoretical Physics 2007年第5期47卷 816-820页

作者： lin Xiu CHEN Mei-Ying lin Xiu-Min li hong-Cai YANG Rong-Can School of Physics and OptoElectronics Technology Fujian Normal University Fuzhou 350007 China

We present a scheme for transferring atomic entangled states via adiabatic passage. In the scheme, we use photons to achieve efficient quantum transmission among spatially distant atoms. The probability of the successful transferring quantum state approaches 1. Meanwhile, the scheme is robust against the effects of atomic spontaneous emission.

关键词： quantum state transfer atomic entangled state cavity QED

Faithful Teleportation of an Unknown Atomic-Entangled State Without Bell-State Measurement

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Communications in Theoretical Physics 2008年第3期49卷 621-624页

作者： lin Xiu li hong-Cai YANG Rong-Can HUANG Zhi-Ping School of Physics and OptoElectronics Technology Fujian Normal University Fuzhou 350007 China

An alternative scheme is proposed for teleportation of an unknown atomic-entangled state. The scheme is based on the resonant interaction of a two-mode cavity field with a A-type three-level atom. In contrast with the previously proposed scheme of [Commun. Theor. Phys. 47 （2007） 253], the present scheme is ascendant, since the fidelity is 1.0 in principle similarly without the Bell-state measurement. The scheme may be generalized to not only the teleportation of the cavity-mode-entangled-state but also the teleportation of the multi-atomic entangled states included in generalized GHZ states. And the scheme is experimentally feasible based on the current cavity QED technique.

关键词： teleportation A-type atom two-mode cavity field Bell-state measurement

Dynamic Development of Aphelenchoides besseyi on Rice Plant by Artificial Inoculation in the Greenhouse

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Agricultural Sciences in China 2008年第8期7卷 970-976页

作者： liU Wei-hong lin Mao-song li hong-mei SUN Min-jie Plant Protection College Nanjing Agricultural University Nanjing 210095 P.R.China

A study was done on the relationship between Aphelenchoides besseyi and the symptoms of small grains and erect panicles. This is an important rice disease in Jiangsu Province, China. A. besseyi was extracted from small grains and erect panicles and cultured artificially, and then inoculated into bud and leaf sheaths of seedlings of two Oryza sativa cultivars, namely Zhendao 2 and Wuyunjing 7 in a greenhouse. The effect on rice growth, in particular the small grains and erect panicles, was revealed by the extent of the disease, seed expansion stages, nematode load, and nematode mortality. In contrast to healthy seedlings, the height, length, and the numbers of spikelets of unhealthy panicles of Zhendao 2 were decreased by 6.7, 16.4, and 13.5%, respectively. Before anthesis, nematodes were attracted to the leaf sheath and apical meristem, nematode load increased by 40%; after anthesis, nematodes occurred in spikelets principally and the number increased by 90.8%. The percentages of infected seeds and nematode load were highest in plump seeds and lowest in empty seeds. Nematode mortality on grain with normal endosperm was lower than seeds with abnormal endosperm. Results indicated that A. besseyi was the pathogen in rice with the symptoms of small grains and erect panicles. Wuyunjing 7 manifests only the small grains and erect panicles symptoms and not the symptoms of leaf white-tip. These symptoms of small grains and erect panicles are new symptom records for the disease caused by A. besseyi on rice.

关键词： Aphelenchoides besseyi small grains and erect panicles nematode distribution seed expansion nematodemortality

New Inorganic-organic Hybrid Compound Containing One Dimensional Keggin Polyoxometalate [SiW_(11)O_(39)Co]^(6-) Chains: Preparation, Characterization and Application in Chemically Bulk-modified Electrode

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Chemical Research in Chinese Universities 2008年第2期24卷 129-134页

作者： WANG Xiu-li lin hong-yan liUGuo-cheng CHEN Bao-kuan BI Yan-feng Faculty of Chemistry and Chemical Engineering Bohai University Liaoning Key Laboratry of Applied Chemistry Jinzhou 121000 P. R. China

A new inorganic-organic hybrid compound based on polyoxometalate and organic ligand formulated as （H2bpp）3[SiWliO39Co]-2H20（1）[bpp=l,3-bis（4-pyridyl）propane] was hydrothermally synthesized and structurally characterized by elemental analysis, single-crystal X-ray diffraction, IR, TG, and cyclic voltammetry. Single-crystal X-ray diffraction analysis reveals that compound 1 consists of interesting cobalt-monosubstituted POMs one dimensional chain together with protonated bpp ligands. Additionally, the polyoxoanions combined with the discrete organic substrates by hydrogen bond interactions to afford a supramolecular 3D network structure. The hybrid compound 1 was used as a bulk modifier to fabricate a three-dimensional chemically modified carbon paste electrode（1-CPE） by direct mixing. The electrochemical behavior and electrocatalysis of 1-CPE were studied in detail. The results indicate that 1-CPE has good electrocatalytic activities toward the reduction of nitrite or bromate in 1 mol/L 1-12SO4 aqueous solution. 1-CPE shows remarkable stability that can be ascribed to the insolubility of compound 1 and the supramolecular interactions existed between 1D POM anion chains and organic ligand bpp, which is very important for practical applications in electrode modification.

关键词： Inorganic-organic hybrid Polyoxometalate Electrochemistry Carbon paste electrode Electrocatalysis

SOME RESULTS OF UPPER ATMOSPHERIC COMPOSITION MEASUREMENTS BY A MASS-SPECTROMETER ON BOARD "SZ-2":CHANGE OF COMPOSITIONS DURING SOLAR AND GEOMAGNETIC DISTURBANCES

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空间科学学报 2002年第Z1期22卷 42-48页

作者： QIN Guotai QIU Shiyan HE Aiqing ZHU Yiqiang SUN lilin lin Xianwen li hong XU Xuepei Center for Space Science and Applied Research The Chinese Academy of Sciences Beijing 100080 P.R. China Center for Space Science and Applied Research The Chinese Academy of Sciences Beijing 100080 P.R. China Center for Space Science and Applied Research The Chinese Academy of Sciences Beijing 100080 P.R. China Center for Space Science and Applied Research The Chinese Academy of Sciences Beijing 100080 P.R. China Center for Space Science and Applied Research The Chinese Academy of Sciences Beijing 100080 P.R. China Center for Space Science and Applied Research The Chinese Academy of Sciences Beijing 100080 P.R. China Center for Space Science and Applied Research The Chinese Academy of Sciences Beijing 100080 P.R. China Center for Space Science and Applied Research The Chinese Academy of Sciences Beijing 100080 P.R. China

Upper atmosphere composition data were obtained for the last half year with a quadruple mass spectrometer on board spacecraft "SZ-2" launched on 10 Jan uary 2001. Based on the analysis of these data, the variations of atmospheric compositions in solar and geomagnetic quiet conditions are reported first, then a detailed discussion on the atmospheric composition variations under the so lar and geomagnetic disturbed conditions is given. The results show that near the altitude of 400 km the variations of main atmospheric compositions corre sponding to solar disturbances are more remarkable in the sunlit area than in the shade area. On the contrary, in geomagnetic disturbance events the corre sponding variations are more obvious in the shade area, an evident increase of N2 density at relatively higher latitudes was observed.

关键词： Solar activity, Geomagnetic activity, Atmospheric composition

Chordoid meningioma:a report of two cases

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Chinese Medical Journal 2007年第8期120卷 726-728页

作者： liU Ai-jun WANG Fu-lin li Xiang-hong Department of Pathology Chinese PLA General Hospital Beijing 100853 China

Although meningiomas are common rumors in adults, the chordoid variant is very rare. According to the World Health Organization Classification of Tumors of the Nervous System （Lyon, 2000）,chordoid meningioma together with another rare variant, lymphoplasmacyterich meningioma, usually contain abundant lymphoplasmacytic infiltration, and are associated even with hematological abnormalities, especially in young adults. Few cases of chordoid meningioma have been reported in detail until Couce and his colleagues reported a sizable series of forty-two cases. Even then, the clinical and pathological features of these tumors were not well characterized, because of variations in different papers. In the present article, we report two adult patients with chordoid meningioma.

关键词： chordoid meningioma case report

坝基界面在非线性水压力驱动下的非线性断裂过程模拟

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工程力学 2017年第4期34卷 42-48页

作者：钟红林皋李红军大连理工大学建设工程学部大连116023 中国水利水电科学研究院岩土所北京100044

基于多边形比例边界有限元法和粘聚裂缝模型提出了混凝土坝坝基界面在随缝宽非线性变化的水压力驱动下的非线性断裂数值模型。混凝土和基岩采用多边形比例边界单元模拟,界面裂缝的断裂过程区采用粘性界面单元模拟。因为界面裂缝总是处... 详细信息

基于多边形比例边界有限元法和粘聚裂缝模型提出了混凝土坝坝基界面在随缝宽非线性变化的水压力驱动下的非线性断裂数值模型。混凝土和基岩采用多边形比例边界单元模拟,界面裂缝的断裂过程区采用粘性界面单元模拟。因为界面裂缝总是处于复合断裂模态,故同时引入了法向和切向的界面单元,且考虑了裂纹面作用有法向和切向任意荷载时的应力强度因子求解。以裂尖为原点,裂尖附近的位移场和应力场在径向上解析求解,在环向具有有限元精度。因此无需在裂尖附近加密网格或采用富集技术即可求得高精度的解。对于界面断裂,可模拟出与两种材料差异性相关的非1/2奇异性。断裂过程区的水压力随缝面宽度变化,采用指数函数的形式进行表征,通过参数调整可实现不同分布的水压力的模拟。水压力与粘聚力考虑为与裂缝宽度相关的组合函数,便于非线性迭代的实现。结合多边形网格生成和重剖分技术,可方便地模拟界面裂缝在水力驱动下的扩展过程。算例研究表明了该文模型的有效性,从中也可看出考虑缝内水压及其具体分布形式对研究坝的稳定性具有重要影响。

关键词：混凝土坝水力劈裂界面断裂比例边界有限元法粘聚裂缝模型

Efficacy of transcutaneous electrical acupoint stimulation(TEAS)for menopausal insomnia and its effect on serum hormone levels

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Journal of Acupuncture and Tuina Science 2020年第3期18卷 197-202页

作者： Wang Min-chao lin li-hong lishui Second People's Hospital Zhejiang 323000China

Objective:To explore the therapeutic efficacy and mechanism of transcutaneous electrical acupoint stimulation(TEAS)for menopausal ***:A total of 80 patients with menopausal insomnia were randomly divided into a control group and an observation group,with 40 cases in each *** patients in the control group received conventional Western medication treatment,and the patients in the observation group received TEAS on the basis of conventional Western medication *** treatment for both groups lasted for 4 *** and after treatment,Pittsburgh sleep quality index(PSQI)and modified Kupperman scale were evaluated,and the serum levels of estradiol(E2)and follicular stimulating hormone(FSH)were *** therapeutic efficacy was evaluated after ***:After treatment,the total effective rate of the observation group was significantly higher than that of the control group(P0.05);the PSQI and Kupperman scores in the observation group were significantly improved after treatment(both P0.05);the serum E2 level was significantly increased(P<0.05),and the FSH level was decreased(P<0.05)in the observation group after treatment,and the between-group differences in serum levels of E2 and FSH were significant(both P<0.05).Conclusion:TEAS plus conventional Western medication in treating menopausal insomnia is effective,and can significantly improve the symptoms of insomnia and menopause,which may be related to the regulation of serum E2 and FSH levels.

关键词： Acupoint Therapy Transcutaneous Electric Nerve Stimulation Insomnia Climacteric Perimenopause Hormones Women