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重视胆囊癌的临床和基础研究

中华消化外科杂志 2025年第1期24卷 64-71页

作者：刘颖斌陈炜上海交通大学医学院附属仁济医院胆胰外科，上海　200127

胆囊癌是我国胆道系统最常见的恶性肿瘤，具有恶性程度高、手术切除率低、术后复发率高和放化疗不敏感等特点。改善胆囊癌预后，有赖于早期诊断、规范化的外科治疗和有效的综合治疗措施。这离不开深入开展胆囊癌的流行病学调查，以及探... 详细信息

胆囊癌是我国胆道系统最常见的恶性肿瘤，具有恶性程度高、手术切除率低、术后复发率高和放化疗不敏感等特点。改善胆囊癌预后，有赖于早期诊断、规范化的外科治疗和有效的综合治疗措施。这离不开深入开展胆囊癌的流行病学调查，以及探索肿瘤系统调控因素和微环境在胆囊癌发生、发展中的新机制。完善各期胆囊癌外科根治性切除范围和诊治流程，加强胆囊癌相关基础与临床转化研究，探索其生物学规律，有助于解决临床难题。

关键词：胆囊肿瘤外科手术诊断新辅助基础研究

Bilayered Dion–Jacobson lead-iodine hybrid perovskite with aromatic spacer for broadband photodetection

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Chinese Chemical Letters 2025年第2期36卷 586-589页

作者： Dongying Fu lin Pan Yanli Ma Yue Zhang Institute of Crystalline Materials Shanxi University State Key Laboratory of Quantum Optics and Quantum Optics Devices Shanxi University

Dion-Jacobson （DJ） phase hybrid perovskites have been proven to improve the photovoltaic performance of the devices due to its unique *** present,some DJ hybrid perovskites have been reported and used for photodetection filed,but most of them are based on lead-bromide systems,which is not conducive to construct broadband photodetection devices due to the limitation of intrinsic ***,we constructed a bilayered DJ hybrid perovskite （3AMPY）(EA)Pb2I7(3AMPY2+is 3-（aminomethyl）pyridinium,EA+is ethylammonium) using an aromatic spacer,which exhibit large current on/off ratios of 10～4under 520 and 637 nm *** particular,the single crystal device based on （3AMPY）(EA)Pb2I7shows a distinguished detectivity of 7.4×1012Jones and a high responsivity of 0.89A/W under 637 nm *** finding not only enriches the quantities of DJ hybrid perovskites,but also provides useful assistance for constructing high-performance optoelectronic device in the future.

关键词： Aromatic spacer Broadband photodetection Dion–Jacobson Hybrid perovskite Two-dimensional

Pyroptosis,ferroptosis,and autophagy in spinal cord injury:regulatory mechanisms and therapeutic targets

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Neural Regeneration Research 2025年第10期20卷 2787-2806页

作者： Qingcong Zheng Du Wang Rongjie lin Weihong Xu Department of Spinal Surgery the First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian ProvinceChina Arthritis Clinical and Research Center Peking University People’s HospitalBeijingChina Department of Orthopedic Surgery Fujian Medical University Union HospitalFuzhouFujian ProvinceChina

Regulated cell death is a form of cell death that is actively controlled by *** studies have shown that regulated cell death plays a key role after spinal cord *** and ferroptosis are newly discovered types of regulated cell deaths that have been shown to exacerbate inflammation and lead to cell death in damaged spinal ***,a complex form of cell death that is interconnected with various regulated cell death mechanisms,has garnered significant attention in the study of spinal cord *** injury triggers not only cell death but also cellular survival *** signaling pathways play pivotal roles in influencing the processes of both deterioration and repair in spinal cord injury by regulating pyroptosis,ferroptosis,and ***,this review aims to comprehensively examine the mechanisms underlying regulated cell deaths,the signaling pathways that modulate these mechanisms,and the potential therapeutic targets for spinal cord *** analysis suggests that targeting the common regulatory signaling pathways of different regulated cell deaths could be a promising strategy to promote cell survival and enhance the repair of spinal cord ***,a holistic approach that incorporates multiple regulated cell deaths and their regulatory pathways presents a promising multi-target therapeutic strategy for the management of spinal cord injury.

关键词： autophagy cell death ferroptosis inflammation pathological mechanisms pyroptosis regulated cell death regulatory pathways spinal cord injury therapeutic targets

Low-profile,low sidelobe array antenna with ultrawide beam coverage for UAV communication

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Chinese Journal of Aeronautics 2025年第1期38卷 444-454页

作者： Mei LI Zhiliang SHANG lin PU Ming-Chun TANG Lei ZHU School of Microelectronics and Communication Engineering Chongqing UniversityChongqing 400044China Department of Electrical and Computer Engineering University of MacaoMacao SAR 999078China

This paper presents a design method to implement an antenna array characterized by ultra-wide beam coverage,low profile,and low Sidelobe Level(SLL)for the application of Unmanned Aerial Vehicle(UAV)air-to-ground *** array consists of ten broadside-radiating,ultrawide-beamwidth elements that are cascaded by a central-symmetry series-fed network with tapered currents following Dolph-Chebyshev distribution to provide low ***,an innovative design of end-fire Huygens source antenna that is compatible with metal ground is presented.A low-profile,half-mode Microstrip Patch Antenna(MPA)is utilized to serve as the magnetic dipole and a monopole is utilized to serves as the electric dipole,constructing the compact,end-fire,grounded Huygens source ***,two opposite-oriented end-fire Huygens source antennas are seamlessly integrated into a single antenna element in the form of monopole-loaded MPA to accomplish the ultrawide,broadside-radiating *** consideration has been applied into the design of series-fed network as well as antenna element to compensate the adverse coupling effects between elements on the radiation *** indicates an ultrawide Half-Power Beamwidth(HPBW)of 161°and a low SLL of-25 dB with a high gain of 12 d Bi under a single-layer *** concurrent ultrawide beamwidth and low SLL make it particularly attractive for applications of UAV air-to-ground communication.

关键词： Array antenna Broad beam Fan beam Low sidelobe level Chebyshev synthesis UAV communication

Use of forestry waste as an alternative raw material for generating metallurgical coke

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Journal of Iron and Steel Research International 2025年第1期32卷 25-39页

作者： lin-bo Qin Wei Qin An-yi Wang ling Shi Jun Han College of Resources and Environment Engineering Wuhan University of Science and TechnologyWuhan430081HubeiChina Hubei Key Laboratory of Industrial Fume and Dust Pollution Control Jianghan UniversityWuhan430056HubeiChina Hubei Key Laboratory for Efficient Utilization and Agglomeration of Metallurgic Mineral Resources Wuhan University of Science and TechnologyWuhan430081HubeiChina

Forestry waste(FW)is a significant renewable energy source in *** substitution of coal blends(BC)with forestry waste to produce metallurgical coke was investigated aiming at expanding alternative resources and reducing CO_(2)emissions in ironmaking *** BC with different ratios of FW were carbonized in a fixed bed reactor,and the physicochemical structure of the coke derived from FW/BC co-carbonization was characterized by Fourier transform infrared spectroscopy,X-ray photoelectron spectroscopy,solid-state^(13)C nuclear magnetic resonance,optical microscopy,and scanning electron *** results reveal that the suitable incorporation of FW in BC is 10 wt.%,and the index of coke quality exhibits a good correlation with the optical anisotropy index and the aromaticity of the as-obtained *** partial substitution of BC with FW exhibits potential benefits for colloid formation,owing to the higher hydrogen in ***,as the substitution ratio of BC with FW increases,it inhibits coke agglomeration due to more tortuous stacked structures formation during volatile releasing ***,it was identified that the substitution of higher BC ratios with FW results in the partial replacement of aromatic carbons by oxygenlinked carbons and aliphatic *** substitution leads to a reduction in the aromaticity of the as-obtained coke.

关键词： Metallurgical coke Forestry waste Coal blend Co-carbonization Chemical structure

Gas-Solid Flow,Combustion Characteristics,and Gas Emissions in a 75 t/h CFB Boiler Based on the CPFD Method

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Journal of Thermal Science 2025年第1期34卷 323-336页

作者： HUANG Xiankun BAI Zhang ZHU Xiaoli WANG Shuoshuo MU lin GONG Liang College of New Energy China University of Petroleum(East China)Qingdao 266580China Key Laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education School of Energy and Power EngineeringDalian University of TechnologyDalian 116024China

A 3D simulation using Computational Particle Fluid Dynamics(CPFD)methods was used to calculate coal combustion in a 75 t/h industrial-scale circulating fluidized bed(CFB)*** characteristics,gas-solid flow characteristics,and gaseous pollutant emissions of CFB boilers from combustion ignition to stable operation were systematically evaluated in this *** show that the temperature distribution is relatively uniform throughout the *** the combustion process unfolds within the boiler,the gas composition curve strikingly portrays the inverse correlation between CO_(2)and O_(2)*** the combustion reaction progresses,it becomes evident that the concentration of CO_(2)progressively increases,while the concentration of O_(2)concurrently *** inverse relationship underscores the fundamental combustion reaction,where carbon-based fuels react with oxygen to produce carbon dioxide and release ***,a comprehensive analysis has revealed that,from ignition to stable combustion,both nitric oxide(NO)and sulfur dioxide(SO_(2))emissions exhibit a declining *** reduction in pollutant generation is attributed to the improvement in combustion *** complete combustion leads to lower levels of unburned hydrocarbons,which are prone to NO ***,the sulfur content in the fuel is more efficiently oxidized to sulfur trioxide(SO_(3))or bound in sulfates,reducing SO_(2)*** steady state in the simulation,the SO_(2)mass flow rate varies significantly with the furnace height,gradually increasing from 0.07 kg·s^(-1)at 4 m at the bottom of the furnace to a peak of 0.078 kg·s^(-1)at 8 m in the center,and then decreasing to 0.06 kg·s^(-1)at 20m at the top of the furnace.

关键词： circulating fluidized bed particle flow combustion CPFD modeling

Wafer‑Scale Vertical 1D GaN Nanorods/2D MoS_(2)/PEDOT:PSS for Piezophototronic Effect‑Enhanced Self‑Powered Flexible Photodetectors

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Nano-Micro Letters 2025年第3期17卷 102-116页

作者： Xin Tang Hongsheng Jiang Zhengliang lin Xuan Wang Wenliang Wang Guoqiang Li State Key Laboratory of Luminescent Materials and Devices South China University of TechnologyGuangzhou 510640People’s Republic of China Department of Electronic Materials School of Materials Science and EngineeringSouth China University of TechnologyGuangzhou 510640People’s Republic of China

van der Waals(vdW)heterostructures constructed by lowdimensional(0D,1D,and 2D)materials are emerging as one of the most appealing systems in next-generation flexible ***,hand-stacked vdW-type photodetectors are not compatible with large-areaarray fabrication and show unimpressive performance in self-powered ***,vertical 1D GaN nanorods arrays(NRAs)/2D MoS_(2)/PEDOT:PSS in wafer scale have been proposed for self-powered flexible photodetectors arrays *** as-integrated device without external bias under weak UV illumination exhibits a competitive responsivity of 1.47 A W^(−1)and a high detectivity of 1.2×10^(11)Jones,as well as a fast response speed of 54/71μs,thanks to the strong light absorption of GaN NRAs and the efficient photogenerated carrier separation in type-II ***,the strain-tunable photodetection performances of device have been ***,the device at−0.78%strain and zero bias reveals a significantly enhanced photoresponse with a responsivity of 2.47 A W^(−1),a detectivity of 2.6×10^(11)Jones,and response times of 40/45μs,which are superior to the state-of-the-art self-powered flexible *** work presents a valuable avenue to prepare tunable vdWs heterostructures for self-powered flexible photodetection,which performs well in flexible sensors.

关键词： Vertical nanorod arrays van der Waals heterostructure Piezophototronic effect Self-powered photodetection Flexible sensors

Predictor−corrector inverse design scheme for property−composition prediction of amorphous alloys

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Transactions of Nonferrous Metals Society of China 2025年第1期35卷 169-183页

作者： Tao LONG Zhi-lin LONG Bo PANG School of Mechanical Engineering and Mechanics Xiangtan UniversityXiangtan 411105China School of Civil Engineering Xiangtan UniversityXiangtan 411105China

In order to develop a generic framework capable of designing novel amorphous alloys with selected target properties,a predictor−corrector inverse design scheme(PCIDS)consisting of a predictor module and a corrector module was presented.A high-precision forward prediction model based on deep neural networks was developed to implement these two *** utmost importance,domain knowledge-guided inverse design networks(DKIDNs)and regular inverse design networks(RIDNs)were also *** forward prediction model possesses a coefficient of determination(R^(2))of 0.990 for the shear modulus and 0.986 for the bulk modulus on the testing ***,the DKIDNs model exhibits superior performance compared to the RIDNs *** is finally demonstrated that PCIDS can efficiently predict amorphous alloy compositions with the required target properties.

关键词： amorphous alloys machine learning deep neural networks inverse design elastic modulus

Highly Oxidized Molecules Make a Significant Contribution to Enhanced Aromatic-Derived Secondary Organic Aerosol under a Humid Environment

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Advances in Atmospheric Sciences 2025年第4期42卷 641-652页

作者： Zhaomin YANG Kun LI lin DU Environment Research Institute Shandong UniversityQingdao 266237China

Enhanced mass concentrations of aromatic-derived secondary organic aerosol(SOA)are frequently observed during humid-haze ***,the influencing mechanism of relative humidity(RH)in aromatic-derived SOA formation remains incompletely ***,the RH dependence of SOA formation in the presence of NOx was explored by a series of chamber experiments for toluene(TOL)and 1,3,5-trimethylbenzene(TMB)*** yield of TOL SOA and TMB SOA increased by 221%and 52%with increasing RH from~8%to~70%,*** results from a high-resolution mass spectrometer showed that SOA constituents with high oxygen content(O/C>0.6)were more abundant in SOA formed in the~70%RH *** elevated yields and O/C of SOA could be attributed to the promoted formation and particle-phase diffusivity of highly oxidized *** addition,in comparison with TMB,TOL could produce more unsaturated aldehydes,which are oxidized into carboxylic acids with high O/C,leading to a more sensitive response of TOL SOA formation to the change in *** work provides mechanistic insights into RH roles in aromatic SOA formation and is helpful for a better understanding of humid-haze events.

关键词： secondary organic aerosol aromatic hydrocarbons highly oxidized molecules relative humidity