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Conserved noncoding sequences correlate with distant gene contacts in Arabidopsis and Brassica

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Journal of Integrative Plant Biology 2023年第6期65卷 1467-1478页

作者： Lei Zhang Jian Wu Jianli liang Runmao lin Chao Sun Qirui Dai Lupeng Zhang Huiling Guo Ranze Zhao Xiaowu Wang State Key Laboratory of Vegetable Biobreeding Institute of Vegetables and FlowersChinese Academy of Agricultural SciencesBeijing 100081China Research Institute of Forestry Chinese Academy of ForestryBeijing 100091China

Physical contact between genes distant on chromosomes is a potentially important way for genes to coordinate their *** investigate the potential importance of distant contacts,we performed high-throughput chromatin conformation capture(Hi-C)experiments on leaf nuclei isolated from Brassica rapa and Brassica *** then combined our results with published Hi-C data from Arabidopsis *** found that distant genes come into physical contact and do so preferentially between the proximal promoter of one gene and the downstream region of another *** with higher numbers of conserved noncoding sequences(CNSs)nearby were more likely to have contact with distant *** more CNSs came higher numbers of transcription factor binding sites and more histone modifications associated with the *** addition,for the genes we studied,distant contacting genes with CNSs were more likely to be transcriptionally *** observations suggest that CNSs may enrich active histone modifications and recruit transcription factors,correlating with distant contacts to ensure coordinated *** study advances our knowledge of gene contacts and provides insights into the relationship between CNSs and distant gene contacts in plants.

关键词： Arabidopsis Brassica conserved noncoding sequences distant gene contacts Hi-C

The influence of water-based drilling fluid on mechanical property of shale and the wellbore stability

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Petroleum 2016年第1期2卷 61-66页

作者： Shu He Lixi liang Yinjin Zeng Yi Ding Yongxue lin Xiangjun Liu Sinopec Research Institute of Petroleum Engineering Beijing 100101China State Key Lab of Oil&Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengduSichuan 610500China

Because of high cost and pollution of oil-based drilling fluid,the water-based drilling fluid is increasingly used ***,bedding planes and micro-cracks are rich in shale *** water-based drilling fluid contacts formation rock,it causes the propagation of crack and invasion of drilling fluid,which decrease shale strength and cause wellbore *** this paper,we analyzed influence of water-based drilling fluid on shale strength and failure mode by mechanics *** on those experimental results,considering the effect of bedding plane and drilling time,we established modeling of wellbore stability for shale *** result from this model indicates that in certain azimuth of horizontal well,collapsing pressure increases dramatically due to shale failure along with bedding *** drilling operation,those azimuths are supposed to be *** model is applicable for predication of collapsing pressure in shale formation and offers reference for choosing suitable mud weight.

关键词： Water-based drilling fluid Shale Bedding plane Wellbore stability

A Noncovalently Fused-Ring Asymmetric Electron Acceptor Enables Efficient Organic Solar Cells

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Chinese Journal of Chemistry 2021年第10期39卷 2685-2691页

作者： Ji lin Qing Guo Qi Liu Junfang Lv Haiyan liang Yang Wang Lei Zhu Feng Liu Xia Guo Maojie Zhang Laboratory of Advanced Optoelectronic Materials College of ChemistryChemical Engineering and Materials ScienceSoochow UniversitySuzhouJiangsu215123 China Frontiers Science Center for Transformative Molecules School of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai 200240China Henan Institute of Advanced Technology Zhengzhou UniversityZhengzhouHenan450003 China

Main observation and conclusion Recently,the asymmetric nonfullerene acceptors(NFAs)with acceptor-donor-acceptor(A-D-A)structure have been developed rapidly,especially for the modification of asymmetric core,asymmetric side chains and asymmetric end *** this work,a novel asymmetric A-D-π-A type NFA with a noncovalently fused-ring core named PIST-4F is synthesized,containing an indacenodithieno[3,2-b]dithiophene(IDT),two strong electron-withdrawing end groups and an alkylthio-substituted thiopheneπ-*** from the S···S noncovalent interaction between the sulfur atom onπ-bridge and the adjacent thiophene in IDT,the PIST-4F presents nearly planar geometry and extended conjugated area,resulting in the optimized electronic properties,charge transport,and film morphology compared to the symmetric NFA *** a result,PM6:PIST-4F-based devices achieve a higher power conversion efficiency(PCE)of 13.8%,while the PM6:PI-4F-based devices only show a PCE of 7.1%.Notably,the PM6:PIST-4F-based devices processed with nonhalogen solvent toluene exhibit an excellent PCE as high as 13.1%.These results indicate that PIST-4F is an effective acceptor for high-efficiency organic solar cells.

关键词： Organic solar cells Asymmetric synthesis π-bridge Noncovalent interactions Electron transport

Spongiosum-combined glanuloplasty reduces glans complications after proximal hypospadias repair

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Asian Journal of Andrology 2021年第5期23卷 532-536页

作者： Yi-Qing Lyu lin Yu Hua Xie Yi-Chen Huang Xiao-Xi Li Li Sun Yan liang Fang Chen Department of Urology Shanghai Children's HospitalShanghai Jiao Tong UniversityShanghai 200040China

We aim to design a new glanuloplasty procedure combined with spongiosum to reduce the incidence of glans dehiscence and coronal fistula after proximal hypospadias *** who underwent urethroplasty by dorsal preputial island flap for proximal hypospadias between January 2014 and December 2016 were reviewed in this retrospective cohort *** who underwent spongiosum-combined glanuloplasty comprised the new-maneuver group,whereas those who underwent conventional glanuloplasty comprised the control *** incidence of complications was then *** the new-maneuver group,dysplastic corpus spongiosum alongside lateral Buck's fascia(0.3-0.4 cm wide)on both sides of the urethral plate was separated from the proximal normal spongy tissue,joining into the glans wings to increase tissue volume and covering the neourethra in the glans *** the control group,the neourethra was covered with superficial fascia under the coronal *** a result,the new-maneuver and control groups comprised 47 and 28 patients,*** the new-maneuver group,no glans dehiscence was detected;however,two(4.3%)patients had coronal fistula,two(4.3%)had urethral stricture,and four(8.5%)had *** the control group,two(7.1%)patients had glans dehiscence,eight(28.6%)had coronal fistula,four(14.3%)had urethral stricture,one(3.6%)had diverticulum,and one(3.6%)had penile curvature *** new-maneuver group had less incidences of coronal fistula(P<0.001),glans dehiscence(P=0.033),and urethral stricture(P=0.008)but had a higher incidence of diverticulum than the control group(P=0.040).It clearly demonstrates that spongiosum-combined glanuloplasty can significantly reduce the incidences of coronal fistula and glans dehisce.

关键词： glans dehiscence glanuloplasty hypospadias urinary fistula

One-pot Three-component Synthesis of 4,4'-Arylidene-bis(3-methyl-pyrazolones) Derivatives in Water

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Chemical Research in Chinese Universities 2012年第6期28卷 999-1002页

作者： JIA Xu-dong DUAN Hal-feng lin Ylng-jle CAO Jun-gang liang Da-peng WU Mao-cheng Department of Organic Chemistry College of Chemistry Jilin University Changehun 130012 P. R. China

Aldehydes,hydrazine and ethyl acetoacetate were used for the synthesis of 4,4＇-arylidene-bis（3-methyl-pyrazolones） derivatives in *** this green synthetic protocol,the solvent water itself catalyzed the reaction via hydrogen bonding,thus avoiding the use of any other catalyst to make the work up procedure ***-pot,environmental friendly and convenient are the highlights.

关键词： 4 4'-Arylidene-bis(3-methyl-pyrazolones) Catalysis Multi-component reaction

Vertical 3D Printed Pd/TiO_(2) Arrays for High Efficiency Photo-assisted Catalytic Water Treatment

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Chemical Research in Chinese Universities 2023年第6期39卷 891-901页

作者： FU Chenhao LI Dan ZHANG Jianwei GUO Wei YANG He ZHAO Bo CHEN Zhaomin FU Xin liang Zhiqiang JIANG lin Institute of Functional Nano and Soft Materials Laboratory(FUNSOM)and Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices Soochow UniversitySuzhou 215123P.R.China Shanghai Institute of Satellite Engineering Shanghai 200240P.R.China

Catalytic degradation of organic contaminants is at the frontier of water treatment due to its selectivity,energy savings,and ability to convert harmful contaminants into harmless or even valuable chemical products for ***,achieving sufficiently high performance in the catalytic removal of organic contaminants for practical application is still extremely ***,we report a Pd-decorated TiO_(2)(Pd/TiO_(2))hierarchical vertical array for fast and efficient catalytic water *** a forest-like Pd/TiO_(2) vertical array demonstrates the following distinct advantages over conventional planar or bulk catalytic systems:1)abundant anchoring sites for nanocrystals loading;2)high sunlight absorption;3)efficient mass transfer channels for the reactants and *** a proof of concept,the Pd/TiO_(2) array demonstrated rapid and efficient photo-assisted catalytic reduction of high concentrations of 4-nitrophenol wastewater(2 g/L,ca.14.38 mmol/L)and its feasibility for continuous flow wastewater *** turnover frequency(TOF)value of the Pd/TiO_(2) array was up to 8.00 min^(-1),which was approximately 4.2 times that of planar Pd/TiO_(2) film with the same area(1.91 min^(-1)).Our strategy of incorporating nanocatalysts with a hierarchical vertical array provides a promising approach to boosting the catalytic performance of catalysts for different chemical reactions.

关键词： 3D printing TiO_(2) Hierarchical vertical array Catalytic water treatment 4-Nitrophenol

Texture and Geochemistry of Multi-stage Hydrothermal Scheelite in the Mamupu Cu-Au-Mo(-W)Deposit,Eastern Tibet:Implications for Tungsten Mineralization in the Yulong Belt

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Acta Geologica Sinica(English Edition) 2024年第3期98卷 701-716页

作者： ZHANG Xiaoxu TANG Juxing lin Bin WANG Qin HE liang YAN Gang SHAO Rui WU Qiang DU Qiu ZHAXI Pingcuo Chengdu Center China Geological Survey(Geosciences Innovation Center of Southwest China)Chengdu 610081China MNR Key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesChinese Academy of Geological SciencesBeijing 100037China SinoProbe Laboratory Chinese Academy of Geological SciencesBeijing 100094China Earth Sciences College Chengdu University of TechnologyChengdu 610059China No.6 Geological Party Tibetan Bureau of Geology and Mineral Exploration and DevelopmentLhasa 851400China Tibet Shengyuan Mining Group Co. Ltd.Lhasa 851400China

Multistage tungsten mineralization was recently discovered in the Mamupu copper-polymetallic deposit in the southern Yulong porphyry copper belt(YPCB),*** study reports the results of cathodoluminescence,trace element and Sr isotope analyses of Mamupu scheelite samples,undertaken in order to better constrain the mechanism of W mineralization and the sources of the ore-forming *** different types of scheelite are identified in the Mamupu deposit:scheelite A(Sch A)mainly occurs in breccias during the prograde stage,scheelite B(Sch B)forms in the chlorite-epidote alteration zone in the retrograde stage,while scheelite C(Sch C)occurs in distal quartz sulfide *** extremely high Mo content and negative Eu anomaly in Sch A represent high oxygen fugacity in the prograde *** with ore-related porphyries,Sch A has a similar REE pattern,but with higher ΣREE,more depleted HREE and slightly lower(^(87)Sr/^(86)Sr)i *** features suggest that Sch A is genetically related to ore-related porphyries,but extensive interaction with carbonate surrounding rocks affects the final REE and Sr isotopic *** B shows dark(Sch B-I)and light(Sch B-II)domains under CL *** Sch B-I to Sch B-II,LREEs are gradually depleted,with MREEs being gradually *** C has the highest LREE/HREE ratio,which indicates that it inherited the geochemical characteristics of fluids after the precipitation of HREE-rich minerals,such as diopside and garnet,in the early prograde *** Mo content in Sch B and Sch C gradually decreased,indicating that the oxygen fugacity of the fluids changed from oxidative in the early stages to reductive in the later,the turbulent Eu anomaly in Sch B and Sch C indicating that the Eu anomaly in the Mamupu scheelite is not solely controlled by oxygen *** extensive interaction of magmatic-hydrothermal fluids and carbonate provides the necessary Ca^(2+)for the precipitation of scheelite in the Mamupu deposit.

关键词： scheelite geochemistry Mamupu Cu deposit Yulong porphyry copper belt eastern Tibet

Advances in Urban Meteorological Research in China

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Journal of Meteorological Research 2020年第2期34卷 218-242页

作者： Shiguang MIAO Weimei JIANG Ping liang Hongnian LIU Xuemei WANG Jianguo TAN Ning ZHANG Ju LI Wupeng DU lin PEI Institute of Urban Meteorology China Meteorological Administration(CMA)Beijing 100089 School of Atmospheric Sciences Nanjing UniversityNanjing 210032 Shanghai Climate Center/CMA Key Laboratory for City Mitigation and Adaptation to Climate Change Shanghai 200030 Guangdong-Hongkong-Macao Joint Laboratory of Collaborative Innovation for Environmental Quality Institute for Environmental and Climate ResearchJinan UniversityGuangzhou 510632 Beijing Climate Center Beijing 100089

Over the past decades,a large number of studies have been carried out in the field of urban meteorology in *** paper summarizes the main progress in urban meteorology research from four aspects:urban meteorological observation network and field campaign,multi-scale model of urban meteorology,interaction between urban meteorology and atmospheric environment,and the impacts of urbanization on weather and *** advances are as ***’s major cities have established or are improving comprehensive urban meteorological observation networks characterized by multi-platform,multi-variable,multi-scale,multi-link,and ***,Nanjing,Shanghai,and other cities carried out urban meteorological field campaigns,which were included in the WMO research demonstration *** tunnel experiments and scale-model outdoor experiments were successfully ***-scale urban meteorological and air quality prediction numerical model systems have been developed and put into operational *** urban heat island effect;urban impacts on precipitation,regional climate,and air quality;urban planning;and interaction between urban meteorology and atmospheric environment are extensively ***,efforts to improve observational technology,data assimilation,and urban system modeling,to explore the impacts of urbanization on environment and human health,and to provide integrated urban hydro-meteorological climate and environmental services are planned ahead.

关键词： urbanization urban meteorology observation network field campaign multi-scale numerical modeling atmospheric environment

Volume calculation of the spur gear billet for cold precision forging with average circle method

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International Journal of Coal Science & Technology 2014年第4期1卷 456-462页

作者： Wangjun Cheng Chengzhong Chi Yongzhen Wang Peng lin Wei liang Chen Li College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China Key Laboratory of Interface Science and Engineering in Advanced Materials Ministry of EducationTaiyuan University of TechnologyTaiyuan 030024China

Forging spur gears are widely used in the driving system of mining machinery and equipment due to their higher strength and dimensional *** the purpose of precisely calculating the volume of cylindrical spur gear billet in cold precision forging,a new theoretical method named average circle method was put *** this method,a series of gear billet volumes were *** with the accurate three-dimensional modeling method,the accuracy of average circle method by theoretical calculation was estimated and the maximum relative error of average circle method was less than 1.5%,which was in good agreement with the experimental *** errors of the calculated and the experimental for obtaining the gear billet volumes with reference circle method are larger than those of the average circle *** shows that average circle method possesses a higher calculation accuracy than reference circle method(traditional method),which should be worth popularizing widely in calculation of spur gear billet volume.

关键词： Gear billet volume Three-dimensional modeling Cold precision forging Average circle