检索结果-南通市图书馆

Nomograms for predicting pathological response to neoadjuvant treatments in patients with rectal cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2019年第1期25卷 118-137页

作者： dong-lin Ren Juan Li Hui-Chuan Yu Shao-Yong Peng Wei-Da lin Xiao-lin Wang Roshan Ara Ghoorun Yan-Xin Luo Department of Colorectal and Anal Surgery Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital Sun Yat-sen University Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital Sun Yat-sen University Department of Colorectal Surgery Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital Sun Yat-sen University

BACKGROUND In recent decades, neoadjuvant therapy(NT) has been the standardized treatment for locally advanced rectal cancer(LARC). Approximately 8%-35% of patients with LARC who received NT were reported to have achieved a complete pathological response(pCR). If the pathological response(PR) can be accurately predicted, these patients may not need surgery. In addition, no response after NT implies that the tumor is destructive, resistant to both chemotherapy and radiotherapy, and prone to having a high metastatic potential. Therefore,developing accurate models to predict PR has great clinical significance and can help achieve individualized treatment in LARC *** To establish nomograms for predicting PR to different NT regimens based on pretreatment parameters for patients with *** Rectal cancer patients were identified from the database of The Sixth Affiliated Hospital, Sun Yat-sen University from January 2012 to December 2016. Logistic regression and nomograms were developed to predict the probability of pCR and good downstaging to ypT0-2N0M0(ypTNM 0-I), respectively, based on pretreatment parameters for all LARC patients. Nomograms were also developed for three NT regimens(capecitabine/deGramont-RT, mFOLFOX6, and m FOLFOX6-RT) to predict pCR *** Four hundred and three patients were included in this study; 72(17.9%) had pCR at the final pathology report, and 177(43.9%) achieved good downstaging to ypT0-2N0M0(ypTNM 0-I). The nomogram for predicting pCR probability showed that NT regimens, tumor differentiation, mesorectal fascia(MRF) status,and tumor length significantly influenced pCR probability. When predicting the probability of good downstaging, tumor differentiation, MRF status, and clinical T stage were the significant factors. Nomograms were developed based on NT regimens. For the capecitabine/de Gramont-RT group, the multivariate analysis showed that the neutrophil-lymphocyte ratio(NLR) was the only significant factor, thu

关键词： Neoadjuvant therapy Locally advanced rectal cancer Nomogram Prediction of pathological response Complete pathological response Good downstaging

Singlecrystalline V2O5 nanowire/graphene composite as cathode material for lithium-ion batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Singlecrystalline V2O5 nanowire/graphene composite as cathod...

TixSn1-xO3solid solution nano particles as anode material for lithium-ion batteries

第八届中国功能材料及其应用学术会议

作者： HE Qing ZHAO dong-lin ZHU Yang-yang ZHANG Jing-xing State Key Laboratory of Chemical Resource Engineering Key Laboratory of Carbon Fiber and Functional PolymersMinistry of EducationBeijing University of Chemical Technology

ISBN: (纸本)9783037859698

The single crystalline VO nanowire/graphenenanosheets(GNS)composite has been successfully prepared via an easy and facile one-step hydrothermal synthesis *** morphology,structure and electrochemical performance of VOnanowire/GNScomposite as cathodematerial for lithi-um-ion batteries were systematically investigated by transmission electronmicroscope,X-ray diffractionand a variety of electrochemical testing *** VO single crystalline nanowires were supported on the GNS substrate and exhibited excellentelectrochemical *** used as a cathode material of lithium-ion batteries,the compositematerial revealed high initial discharge capacities and exceptional rate *** was found that VO nanowire/GNScomposite exhibited a relativelyhigh reversible capacity of 357 mA h g-land fine cycle performance.

关键词： Graphene V2O5 nanowires Lithium-ion batteries Cathode

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

TixSn1-xO3solid solution nano particles as anode material fo...

Mapping the potential for offshore aquaculture of salmonids in the Yellow Sea

第八届中国功能材料及其应用学术会议

作者： ZHANG Jing-xing ZHAO dong-lin ZHU Yang-yang HE Qing State Key Laboratory of Chemical Resource Engineering Key Laboratory of Carbon Fiber and Functional PolymersMinistry of EducationBeijing University of Chemical Technology

ISBN: (纸本)9783037859698

TiSnOSolid solution nano particles have been successfully prepared via a hydrothermal *** morphology and structure of TiO,SnO and TiSnOsolid solution nano particles were investigated byscanning electron microscopy,transmission electron microscope and X-ray diffraction *** electrochemical performanceof TiO,SnOand TiSnOsolid solution nano particlesas anode material for lithium-ion batteries were systematically investigated bya variety of electrochemical testing *** TiSnOsolid solution nano particles showed not only higher specific capacity of401.3mAh·g after 50 cycles but also better cycle performance,superior than the pure SnO electrode,which can be ascribed to the stable cyclability of TiOand the high reversible capacity of nanosized SnO.

关键词： TiO2 SnO2 Solid solutions Lithium-ion batteries Anode materials

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Marine Life Science & Technology 2022年第3期4卷 329-342页

作者： Shuang‑En Yu Shuang‑lin dong Zhi‑Xin Zhang Yu‑Yang Zhang Gianluca Sarà Jie Wang Yun‑Wei dong Key Laboratory of Mariculture of Ministry of Education College of FisheriesOcean University of ChinaQingdao 266003China Function Laboratory for Marine Fisheries Science and Food Production Processes Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266235China CAS Key Laboratory of Tropical Marine Bio‑Resources and Ecology South China Sea Institute of OceanologyInnovation Academy of South China Sea Ecology and Environmental EngineeringChinese Academy of SciencesGuangzhou 510301China Laboratory of Ecology Department of Earth and Marine SciencesUniversity of Palermo90128 PalermoItaly

Mariculture has been one of the fastest-growing global food production sectors over the past three *** the congestion of space and deterioration of the environment in coastal regions,offshore aquaculture has gained increasing *** salmon(Salmo salar)and rainbow trout(Oncorhynchus mykiss)are two important aquaculture species and contribute to 6.1%of world aquaculture production of *** the present study,we established species distribution models(SDMs)to identify the potential areas for offshore aquaculture of these two cold-water fish species considering the mesoscale spatio-temporal thermal heterogeneity of the Yellow *** values of the area under the curve(AUC)and the true skill statistic(TSS)showed good model *** suitability index(SI),which was used in this study to quantitatively assess potential offshore aquaculture sites,was highly dynamic at the surface water ***,high SI values occurred throughout the year at deeper water *** potential aquaculture areas for *** and *** in the Yellow Sea were estimated as 52,270±3275(95%confidence interval,CI)and 146,831±15,023 km^(2),*** results highlighted the use of SDMs in identifying potential aquaculture areas based on environmental *** the thermal heterogeneity of the environment,this study suggested that offshore aquaculture for Atlantic salmon and rainbow trout was feasible in the Yellow Sea by adopting new technologies(e.g.,sinking cages into deep water)to avoid damage from high temperatures in summer.

关键词： Aquaculture potential Offshore aquaculture Oncorhynchus mykiss Salmo salar Species distribution models The Yellow Sea Cold Water Mass

Ultra-sensitive flexible Ga_(2)O_(3)solar-blind photodetector array realized via ultra-thin absorbing medium

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2022年第4期15卷 3711-3719页

作者： Yancheng Chen Xun Yang Yuan Zhang Xuexia Chen Junlu Sun Zhiyang Xu Kaiyong Li lin dong Chongxin Shan Henan Key Laboratory of Diamond Optoelectronic Materials and Devices Key Laboratory of Materials PhysicsMinistry of EducationSchool of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China

The quest for solar-blind photodetectors with outstanding optoelectronic properties and weak signals detection capability is essential for their applications in the field of imaging,communication,warning,*** date,Ga_(2)O_(3)has demonstrated potential for high-performance solar-blind ***,the performance usually decays superlinearly at low light intensities due to carrier-trapping effect,which limits the weak signal detection capability of Ga_(2)O_(3)***,a Ga_(2)O_(3)solarblind photodetector with ultra-thin absorbing medium has been designed to restrain trapping of photo-generated carriers during the transporting process by shortening the carrier transport ***,multiple-beam interference is employed to enhance the absorption efficiency of the Ga_(2)O_(3)layer using an Al/Al_(2)O_(3)/Ga_(2)O_(3)*** on the ultra-thin absorbing medium with enhanced absorption efficiency,a 7×7 flexible photodetector array is developed,and the detectivity can reach 1.7×10^(15)Jones,which is among the best values ever reported for Ga_(2)O_(3)***,the performance of the photodetector decays little as the illumination intensity is as weak as 5 nW/cm2,revealing the capacity to detect ultra-weak *** addition,the flexible photodetector array can execute the functions of imaging,spatial distribution of light source intensity,real-time light trajectory detection,*** results may provide a route to high-performance solar-blind photodetectors for ultra-weak light detection.

关键词： Ga_(2)O_(3) solar-blind detection ultra-thin absorbing medium multiple-beam interference flexible array

Hybrid 2D/3D Graphitic Carbon Nitride-Based High-Temperature Position-Sensitive Detector

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Energy & Environmental Materials 2024年第1期7卷 275-283页

作者： Xuexia Chen dongwen Yang Xun Yang Qing Lou Zhiyu Liu Yancheng Chen Chaofan Lv lin dong Chongxin Shan Henan Key Laboratory of Diamond Optoelectronic Materials and Devices Key Laboratory of Material PhysicsMinistry of EducationSchool of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China

Ultraviolet position-sensitive detectors(PSDs)are expected to undergo harsh environments,such as high temperatures,for a wide variety of applications in military,civilian,and ***,no report on relevant PSDs operating at high temperatures can be found up to ***,we design a new 2D/3D graphitic carbon nitride(g-C_(3)N_(4))/gallium nitride(GaN)hybrid heterojunction to construct the ultraviolet high-temperature-resistant *** g-C_(3)N_(4)/GaN PSD exhibits a high position sensitivity of 355 mV mm^(-1),a rise/fall response time of 1.7/2.3 ms,and a nonlinearity of 0.5%at room *** ultralow formation energy of-0.917 eV atom^(-1)has been obtained via the thermodynamic phase stability calculations,which endows g-C_(3)N_(4)with robust stability against *** merits of the strong built-in electric field of the 2D/3D hybrid heterojunction and robust thermo-stability of g-C_(3)N_(4),the g-C_(3)N_(4)/GaN PSD delivers an excellent position sensitivity and angle detection nonlinearity of 315 mV mm^(-1)and 1.4%,respectively,with high repeatability at a high temperature up to 700 K,outperforming most of the other counterparts and even commercial silicon-based *** work unveils the high-temperature PSD,and pioneers a new path to constructing g-C_(3)N_(4)-based harsh-environment-tolerant optoelectronic devices.

关键词： graphitic carbon nitride high-temperature stability lateral photovoltaic effect position-sensitive detectors two-dimensional materials

Engineering the efficient three-dimension hollow cubic carbon from vacuum residuum with enhanced mass transfer ability towards H2O2 production

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2021年第10期34卷 98-105页

作者： Zhaohui Chen Yasi Mo dong lin Yongxiao Tuo Xiang Feng Yibin Liu Xiaobo Chen De Chen Chaohe Yang State Key Laboratory of Heavy Oil Processing China University of PetroleumQingdao 266580China Department of Chemical Engineering Norwegian University of Science and TechnologyTrondheim 7491Norway

Constructing efficient carbon material with enhanced mass transfer ability from vacuum residuum(VR)is of prime industrial and scientific ***,we demonstrated a one-pot synthesis of metal-free and highly symmetric hollow carbon cubes(HCCs)using cost-efficient vacuum residuum(VR)as a C/N/S *** multi-techniques such as TEM,SEM,Raman,XPS,and XRD,it is found that the CTAB surfactant plays an important role in emulsifying and forming oil-in-water suspension ***,high aromatics contents in VR favor the formation of HCCs shell by graphitization on the surface of Na Cl ***,heavy metals(e.g.,V,Ni)are not enriched in carbon skeleton due to the unique graphitization *** metal-free HCCs catalyst showed good catalytic stability and high selectivity towards direct and local electrochemical production of hydrogen peroxide(H_(2)O_(2))through two-electron O_(2)reduction due to enhanced mass transfer *** results provide a novel avenue to synthesize metal-free cubic carbon material from low-cost and plentiful VR,which are essential to the design of more efficient catalysts for O_(2)reduction to H_(2)O_(2).

关键词： Electrochemistry Hydrogen peroxide Hollow carbon cube Vacuum residuum Catalyst Selectivity

Exploiting quasi-one-dimensional confinement for proficient hydrogen production from formic acid at room temperature

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2020年第10期29卷 205-213页

作者： Tao Jiang Peng Lu Meng-Jiao Xu Jian-dong lin Yong-Mei Liu Yong Cao He-Yong He Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Department of ChemistryFudan UniversityShanghai 200433China

We describe herein that the quasi-one-dimensional confinement effect of functionalized nanoporous supports is particularly advantageous for boosting formic acid(FA)dehydrogenation efficiency over palladium nanoparticles(NPs).Benefiting from their unique structural merits that lead to significant lowering of the entropic barrier for FA activation,the Pd NPs interiorly located on the amino-modified MCM-41 offer the promise of more than an order of magnitude speedup of the initial activity in H2 production from FA over their exterior *** mild and additive-free conditions,ultrafine Pd NPs confined in aminomodified MCM-41 channels exhibit an initial turnover frequency as high as 46,677 h-1 and a turnover number up to 1,060,000 at 60℃.In conjunction with the enhancement and robust performance for efficient regeneration of FA via CO2 hydrogenation,the presented approach greatly contributes to the development of FA-based hydrogen storage and related technologies as viable means of enabling sustainable future energy prospects.

关键词： Confinement effect Formic acid Heterogeneous catalysis Hydrogen storage

Genetic spectrum and clinical features in a cohort of Chinese patients with autosomal recessive cerebellar ataxias

在线全文

学校读者我要写书评

暂无评论

Translational Neurodegeneration 2021年第4期10卷 536-550页

作者： Hao-ling Cheng Ya-Ru Shao Yi dong Hai-lin dong Lu Yang Yin Ma Ying Shen Zhi-Ying Wu Department of Neurology and Research Center of Neurology in Second Affiliated Hospital and Key Laboratory of Medical Neurobiology of Zhejiang ProvinceZhejiang University School of MedicineHangzhou 310000China Department of Neurology Huashan HospitalShanghai Medical CollegeFudan UniversityShanghai 200000China Institute of Neuroscience Zhejiang University School of MedicineHangzhou 310000China CAS Center for Excellence in Brain Science and Intelligence Technology Shanghai 200000China

Background:Although many causative genes have been uncovered in recent years,genetic diagnosis is still missing for approximately 50%of autosomal recessive cerebellar ataxia(ARCA)*** studies have been performed to determine the genetic spectrum and clinical profile of ARCA patients in the Chinese ***:Fifty-four Chinese index patients with unexplained autosomal recessive or sporadic ataxia were investigated by whole-exome sequencing(WES)and copy number variation(CNV)calling with *** causal CNV predictions were validated by ***:Thirty-eight mutations including 29 novel ones were identified in 25 out of the 54 patients,providing a 46.3%positive molecular diagnostic *** different genes were involved,of which four most common genes were SACS,SYNE1,ADCK3 and SETX,which accounted for 76.0%(19/25)of the positive *** de novo microdeletion in SACS was reported for the first time in China and the uniparental disomy of ADCK3 was reported for the first time *** features of the patients carrying SACS,SYNE1 and ADCK3 mutations were ***:Our results expand the genetic spectrum and clinical profiles of ARCA patients,demonstrate the high efficiency and reliability of WES combined with CNV analysis in the diagnosis of suspected ARCA,and emphasize the importance of complete bioinformatics analysis of WES data for accurate diagnosis.

关键词： Autosomal recessive cerebellar ataxias Chinese Genetic spectrum Structural variation Clinical features