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基于改进的粒子群优化的FastSLAM方法

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高技术通讯 2011年第4期21卷 422-427页

作者：刘利枚蔡自兴中南大学信息科学与工程学院智能系统与智能软件研究所长沙410083 湖南商学院计算机与电子工程学院长沙410205

提出了一种基于改进的粒子群优化（IPSO）的快速同时定位和地图创建（FastSLAM）方法——IPSO FastSLAM算法。该算法在粒子预估过程中引入观测信息，调整了粒子的提议分布，增强了位置预测的准确性。改进的粒子群优化采用两步优化策略... 详细信息

提出了一种基于改进的粒子群优化（IPSO）的快速同时定位和地图创建（FastSLAM）方法——IPSO FastSLAM算法。该算法在粒子预估过程中引入观测信息，调整了粒子的提议分布，增强了位置预测的准确性。改进的粒子群优化采用两步优化策略，即首先通过种群速度自适应调整惯性权重，有效地克服了粒子退化问题，改善了算法的实时性，然后针对粒子耗尽问题，在粒子群优化算法中引入遗传算法的变异运算对其进行改进，扩大解空间的范围，从而保持了种群的多样性。仿真和实时数据实验验证了该方法正确、可行。

关键词：粒子群优化(PSO) 快速同时定位和地图创建(FastSLAM) 惯性权重遗传算法提议分布

Sandpaper-templated Stretchable Immunosensing Electrodes for Sub-picomolar Progesterone Detection

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Chemical Research in Chinese Universities 2024年第5期40卷 874-880页

作者： LI Zhaoxian MENG Xingyu FANG Chuyao YI Zhenkai WU Yaoyao liu Xuanxuan ZHONG Wei ZHANG limei XIE Zhuang School of Materials Science and Engineering Key Laboratory for Polymeric Composite and Functional Materials of Ministry of EducationSun Yat-sen UniversityGuangzhou510275P.R.China Reproductive Medicine Center Department of Obstetrics and Gynecologythe First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou510080P.R.China

Female hormone detection,particularly non-invasive monitoring progesterone(P4)levels in body fluids,plays a critical role in female health management and disease ***,the challenge still exists because of the ultralow abundance of P4(<100 pmol/L)in sweat and saliva,necessitating highly sensitive methods for wearable ***,we present a simple sandpaper-templated stretchable immunosensing electrode designed for ultra-sensitive detection of P4 at sub-picomolar level.A molding technique is employed to replicate the sandpaper textures to provide a microstructured elastomeric substrate for electrode *** microstructured surface coated with poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate)(PEDOT:PSS)/LiTFSI[LiTFSI=lithium bis(trifluoromethanesulfonyl)imide]provided a stretchable polymer electrode with high conductivity,and further decoration with gold nanoparticles(AuNPs)enabled the immunosensing for P4 by electrochemical impedance spectroscopy(EIS)*** adjusting the AuNPs deposition conditions,ultrasensitive detection of P4 is realized with a low limit of detection(LOD)of ca.10 fmol/L and a tunable dynamic range up toµmol/***,the stretchable electrode exhibits stable electrochemical performance,enabling the detection of P4 at sub-picomolar levels even under mechanical strain of 30%.This innovative electrochemical sensor holds significant promise for non-invasive,on-site monitoring of P4 levels in healthcare,as well as hormone detection in food safety and environment surveillance.

关键词： Progesterone Immunosensor Microstructured electrode Stretchable biosensor Electrochemical sensing

Researches on New Fault Diagnosis Method for Process Industry Based on Improved SVM Reduction Algorithm

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Researches on New Fault Diagnosis Method for Process Industr...

基于“肠-关节”轴探讨电针对类风湿关节炎模型家兔肠道菌群及血清炎症因子的影响

2012 International Conference on Mechanical Materials and Manufacturing Engineering(ICMMME 2012)

作者： Anna Wang Mo Sha limei liu Maoxiang Chu College of Information Science and Engineering Northeastern University

Once faults happened in the process industry, it will bring on heavy casualties and fatal property losses, even lead to irreclaimable pollution. Combining the large-scale sample set reduction strategy with SVM, this paper proposed a new improved support vector machine(SVM) training algorithm based on support vectors to solve the difficulty of fault diagnosis of process industry. A new reduction algorithm is presented to reduce large-scale sample set. The constraint threshold is introduced in the new algorithm. The new training algorithm can eliminate the samples correspond to non-support vectors so that poor generation ability caused by large-scale training sample set is solved. A new evaluating indicator of large-scale sample set reduction strategy is also proposed in this paper. The improved SVM algorithm proposed is applied to two typical fault diagnosis of process industry. The results of experiments show that the improved SVM algorithm not only reduces greatly the cost of SVM learning but also markedly increases the speed of classification, and at one time the accuracy of fault diagnosis is not debased.

关键词： Fault Diagnosis SVM Reduction SVM

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中国中医药信息杂志 2024年第4期31卷 124-131页

作者：刘翠杜小正井维尧苏成红刘莉梅袁博张星华张枫帆陈平李向军王海东甘肃中医药大学甘肃兰州730000 甘肃中医药大学附属医院甘肃兰州730000 甘肃省中医院甘肃兰州730050

目的观察电针对类风湿关节炎(RA)模型家兔肠道菌群及血清炎性因子的影响,探讨其治疗RA的作用机制。方法采用卵蛋白诱导联合完全弗氏佐剂建立RA家兔模型,将造模成功家兔随机分为模型组、益生菌组和电针组,每组6只,另取6只家兔作为正常组... 详细信息

目的观察电针对类风湿关节炎(RA)模型家兔肠道菌群及血清炎性因子的影响,探讨其治疗RA的作用机制。方法采用卵蛋白诱导联合完全弗氏佐剂建立RA家兔模型,将造模成功家兔随机分为模型组、益生菌组和电针组,每组6只,另取6只家兔作为正常组。电针组电针双侧“足三里”“犊鼻”,30 min/次,益生菌组予益生菌胶囊溶液(14.5 mg/kg)灌胃,均1次/d,连续2周。测量家兔膝关节周径、痛阈,HE染色观察结肠组织和滑膜组织病理形态,16S rDNA测序分析肠道菌群结构变化,ELISA检测血清肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-1β、IL-6含量。结果与正常组比较,模型组家兔膝关节周径显著增加、痛阈显著降低(P<0.01);结肠黏膜损伤严重,杯状细胞缺失,大量炎性细胞浸润;关节囊滑膜表面粗糙,滑膜细胞增生、增厚,炎性细胞浸润明显;肠道菌群物种数目及均匀度减少,变形菌门、厚壁菌门、拟杆菌门相对丰度减少(P<0.05,P<0.01),脱硫杆菌门相对丰度增加(P<0.01),弯曲杆菌属、劳森氏菌属及假单胞菌属相对丰度增加(P<0.01),赫山单胞菌属、草螺菌属相对丰度降低(P<0.01);血清TNF-α、IL-1β、IL-6含量显著升高(P<0.01)。与模型组比较,益生菌组和电针组家兔膝关节周径显著减小、痛阈显著升高(P<0.01,P<0.05);肠黏膜损伤程度减轻,杯状细胞排列基本整齐,炎性细胞浸润减轻;滑膜细胞增生、增厚减轻,少量炎性细胞浸润;肠道菌群物种数目及均匀度增加,变形菌门、厚壁菌门、拟杆菌门相对丰度增加(P<0.05,P<0.01),脱硫杆菌门相对丰度减少(P<0.01),弯曲杆菌属、劳森氏菌属及假单胞菌属相对丰度减少(P<0.01),赫山单胞菌属、草螺菌属相对丰度增加(P<0.05,P<0.01);血清TNF-α、IL-1β、IL-6含量显著降低(P<0.01)。结论电针可显著改善RA家兔症状,降低关节滑膜炎症反应,其机制可能与调控肠道菌群结构有关。

关键词：类风湿关节炎电针肠-关节轴肠道菌群炎性反应兔

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内蒙古东部地区与东三省区域旅游合作的思考

干旱区资源与环境 2011年第6期25卷 196-200页

作者：刘丽梅内蒙古财经学院旅游学院呼和浩特010051

旅游业在区域经济发展中占有举足轻重的地位,内蒙古与东三省的区域旅游合作为双方带来前所未有的机遇,通过对内蒙古东部地区与东三省区域旅游合作现状的分析,发现双方合作中存在着发展状况不平衡,权利分散不便于协调、约束,各参与主体... 详细信息

旅游业在区域经济发展中占有举足轻重的地位,内蒙古与东三省的区域旅游合作为双方带来前所未有的机遇,通过对内蒙古东部地区与东三省区域旅游合作现状的分析,发现双方合作中存在着发展状况不平衡,权利分散不便于协调、约束,各参与主体过分依赖骨干城市,合作中缺少新产品的涌现,企业动力不足,政府行为取代企业行为等诸多问题,针对双方合作中出现的具体问题提出了一些想法和建议。

关键词：区域旅游合作共赢无障碍旅游

Targeted therapeutic effects of oral magnetically driven pectin nanoparticles containing chlorogenic acid on colon cancer

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Particuology 2024年第1期84卷 53-59页

作者： Huatai Zhu limei Zhang Fujia Kou Jingyang Zhao Jiandu Lei Jing He Beijing Key Laboratory of Lignocellulosic Chemistry Beijing Forestry UniversityBeijing100083China Institute of Biopharmaceutical and Health Engineering Tsinghua Shenzhen International Graduate SchoolTsinghua UniversityShenzhen518055China

Oral colonic nano-drug delivery system has attracted growing attention in treating colon cancer for their excellent ***,the unique and complex structure of the gastrointestinal tract is still an obstacle to the safe delivery of drugs targeting sites in colon ***,we designed magnetically driven dual-targeted oral colonic nanoparticles loaded with chlorogenic acid using pectin and oleic acid-modified iron oxide(Fe3O4@OA).Specific degradation of pectin by pectinase produced by colonic flora and magnetic fields applied to the colon confers specific targeting of nanoparticles to the *** order to overcome the challenge of preparing magnetically driven nanoparticles with small and homogeneous particle sizes by a single conventional method,we developed the combined ultrasound-emulsification *** average particle size of the prepared nanoparticles was 81.04±1.02 nm,which showed good drug release in the simulated colonic *** vitro anticancer studies,the drug-loaded nanoparticles possess an obvious toxicity and apoptosis-inducing ability against cancer ***,the hemolysis results demonstrated the safety of the nanoplatform(PET/CGA/Fe_(3)O_(4)@OA).This work holds broad prospects as a new treatment modality for colon cancer.

关键词： Pectin Chlorogenic acid Ultrasound-emulsion Magnetically driven Colon cancer Colon targeted

Enhanced piezoelectricity of Cu-doped K(Ta,Nb)O_(3) single crystals

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Journal of Materiomics 2024年第5期10卷 1017-1025页

作者： Fulin Zhang Songtao Fan Yingxu Zhu Wendie Chen Bing liu Yuguo Yang limei Zheng Yuanyuan Zhang Xianshun Lv Xuping Wang Advanced Materials Institute Qilu University of Technology(Shandong Academy of Sciences)Jinan250014China Qilu University of Technology(Shandong Academy of Sciences) Advanced Materials InstituteKey Laboratory of Light Conversion Materials and Technology of Shandong Academy of SciencesJinan250014China School of Physics Shandong UniversityJinan250100China

As a class of solid solution material,K(Ta,Nb)O3(KTN)single crystals have attracted significant interest due to their excellent piezoelectric and electro-optic *** this study,the piezoelectric properties of KTN were improved through Cu *** the advantages of composition-regulating phase transition,a large,high-quality Cu:KTN crystal measuring 30 mm×25 mm×20 mm in size was grown using the improved top seeded solution growth ***-doped KTN exhibited better piezoelectric properties than pure KTN,and the full matrix parameters were *** dielectric,piezoelectric,and electromechanical coupling responses(ε^(T)_(11)-2,136,d_(33)∼303 pC/N,k_(t)∼0.515,and k33∼0.672)were successfully *** realize the optimized orientation of the piezoelectric properties,the orientation dependence of the single domain properties was investigated,and the mechanism of Cu doping to improve piezoelectric properties was *** found that 0.36%(in mass)Cu doped crystal consisted of A-site substitution,following ferroelectric and domain *** small ferroelectric domain sizes led to a large domain wall mobility rate and high domain wall density,which contributed to high piezoelectric *** work revealed the effect of A-position doping on piezoelectric properties and provided a theoretical and experimental foundation for the performance optimization of KTN-based materials.

关键词： Solid solution material Lead-free piezoelectric Enhanced piezoelectricity

Irrigation and nitrogen fertiliser optimisation in protected vegetable fields of northern China:Achieving environmental and agronomic sustainability

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Journal of Integrative Agriculture 2024年第3期23卷 1022-1033页

作者： Bingqian Fan Yitao Zhang Owen Fenton Karen Daly Jungai Li Hongyuan Wang limei Zhai Xiaosheng Luo Qiuliang Lei Shuxia Wu Hongbin liu State Key Laboratory of Efficient Utilization of Arid and Semi-arid Arable Land in Northern China/Key Laboratory of Nonpoint Source Pollution Control Ministry of Agriculture and Rural Affairs/lnstitute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 100101China Teagasc Environmental Research CentreWexford Y35Ireland Institute of Plant Nutrition Resources and Environmental SciencesHenan Academy of Agricultural SciencesZhengzhou 450002China

Globally,sub-optimal use of nitrogen (N) fertiliser and elevated N irrigation groundwater have led to high leached nitrate (NO_(3)^(–)) losses from protected vegetable field *** fertiliser and irrigation management in different soil types is crucial to reduce future N loads from such *** present 4-year study examined leached N loads from lysimeter monitoring arrays set up across 18 protected vegetable system sites encompassing the dominant soil types of northern *** treatments applied at each field site were:1) a high N and high irrigation input treatment (HNHI);2) a low N but high irrigation input treatment (LNHI) and 3) a low N with low irrigation input treatment (LNLI).Results showed that the mean annual leached total nitrogen loads from the HNHI,LNHI and LNLI treatments were 325,294 and 257 kg N ha^(–1) in the fluvo-aquic soil,114,100 and 78 kg N ha^(–1) in the cinnamon soil and 79,68 and 57 kg N ha^(–1) in the black soil,*** N dissolved in irrigation water in the fluvo-aquic soil areas was 8.26-fold higher than in the cinnamon areas.A structural equation model showed that N fertiliser inputs and leaching water amounts explained 14.7 and 81.8%of the variation of leached N loads,***,reducing irrigation water by 21.5%decreased leached N loads by 20.9%,while reducing manure N and chemical N inputs by 22 and 25%decreased leached N loads by only 9.5%. This study highlights that protected vegetable fields dominated by fluvo-aquic soil need management to curtail leached N losses in northern China.

关键词： agriculture water quality nitrate groundwater irrigation management

Enhancing electrical conductivity and strength in Al alloys by combination of deformation and ageing

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Enhancing electrical conductivity and strength in Al alloys ...