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二维导流管喷动床的流动特征

化工冶金 2000年第4期21卷 369-374页

作者：罗保林 Freitas L A P lim c j Grace j R 中国科学院化工冶金研究所北京100080 加拿大不列颠哥伦比亚大学化工系

带导流管的二维喷动床(2-DSBDP)是传统喷动床的改进型式，矩形床内设置的与床同厚的垂直导流管可以控制固体颗粒的循环速率, 同时使下行区中的气固移动床维持平推流. 本文实验测定了不同表观气速、床层高度、固体颗粒与气体入口尺寸时,... 详细信息

带导流管的二维喷动床(2-DSBDP)是传统喷动床的改进型式，矩形床内设置的与床同厚的垂直导流管可以控制固体颗粒的循环速率, 同时使下行区中的气固移动床维持平推流. 本文实验测定了不同表观气速、床层高度、固体颗粒与气体入口尺寸时, 二维导流管喷动床的床压降及相应的空隙率，藉以阐述2-DSBDP的流动特征.

关键词：二维喷动床导流管流动特征

Prediction of Minimum Spouting Velocity at Elevated Pressures and Temperatures

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Petroleum Science 2006年第2期3卷 81-84页

作者： Wei Weisheng Bao Xiaojun lim c. j. Bi H. T. Key Laboratory of catalys＆ China National Petroleum Corporation China University of Petroleum Beijing 102249 China Department of chemical and Biological Engineering University of British Columbia Vancouver V6T 1Z4 Canada

Minimum spouting velocity （Ums） is one of the most important flow characteristics for proper design and operation of spouted bed reactors. Many correlations for Ums have been published since spouted bed technology was initiated in 1955. In this paper, a new correlation is developed for Ums based on 767 published experimental data covering both high pressure and high temperature conditions. The calculated and the measured results of Ums are in better agreement than other published correlations.

关键词： Spouted bed minimum spouting velocity high temperature high pressure

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矩形导流管喷动床下行区的床层压降

过程工程学报 2004年第Z1期4卷 551-557页

作者：罗保林宗祥荣 lim,c.j. 中国科学院过程工程研究所北京100080 烟台大学化工系山东烟台264005 加拿大不列颠哥伦比亚大学化学与生物技术系温哥华V6T 1Z4

带导流管的矩形喷动床是传统喷动床的改进型式,矩形床内设置的与床同厚的垂直导流管,可以控制固体颗粒的内循环速率,同时使下行区中的气固移动床维持平推流.本文实验测定了不同表观气速、床层重量、不同固体颗粒与气体入口形式与尺寸时... 详细信息

带导流管的矩形喷动床是传统喷动床的改进型式,矩形床内设置的与床同厚的垂直导流管,可以控制固体颗粒的内循环速率,同时使下行区中的气固移动床维持平推流.本文实验测定了不同表观气速、床层重量、不同固体颗粒与气体入口形式与尺寸时,矩形导流管喷动床下行区的床层压降,以考察其流动特征.实验结果表明,下行区存在床层压降的轴向分布,气固流动处于负压差下移上流区,且气固滑移速度自下而上是逐渐下降的.下行区颗粒床层的压降以及颗粒的移动下输,受到喷动床表观气速、床高、喷嘴尺寸、物料种类和颗粒直径的不同影响.

关键词：矩形喷动床导流管下行区床层压降

Single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： Muhammad junaid Eun jeong Lee Su Bin lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

Status and prospects for symmetric organic redox flow batteries

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journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon c.Daeschler Katelyn j.W.So Konstantin Feinberg Marina Manoraj jenny cheung jennifer Zhang Kaveh Mirmoeini jPaul Santerre Tessa Gordon Gregory HBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

Is a nanorod (or nanotube) with a lower Young’s modulus stiffer? Is not Young’s modulus a stiffness indicator?

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Science china(Physics,Mechanics & Astronomy) 2010年第4期53卷 712-724页

作者： lim c. W. Department of Building and construction City University of Hong Kong

It has been a known fact in classical mechanics of materials that Young’s modulus is an indicator of material stiffness and materials with a higher Young’s modulus are stiffer. At the nanoscale, within the scope and under specific circumstances described in this paper, however, a nanorod (or a nanotube) with a smaller Young’s modulus (smaller stress-strain rate) is stiffer. In such a scenario, Young’s modulus is not a stiffness indicator for nanostructures. Furthermore, the nonlocal stress-strain rate is dependent on types of load, boundary conditions and location. This is likely to be one of the many possible reasons why numerous experiments in the past obtained significantly varying values of Young’s modulus for a seemingly identical nanotube, i.e. because the types of loading and/or boundary conditions in the experiments were different, as well as at which point the property was measured. Based on the nonlocal elasticity theory and within the scope of material and geometric linearity, this paper reports the strange and hitherto unrealized effect that a nanorod (or a nanotube) with a lower Young’s modulus (smaller stress-strain rate) indicates smaller extension in tensile analysis. Similarly, it is also predicted that a nanorod (or a nanotube) with a lower Young’s modulus results in smaller bending deflection, higher critical buckling load, higher free vibration frequency and higher wave propagation velocity, which are at all consequences of a stiffer nanostructure.

关键词： nanorod nanotube nonlocal stress nonlocal elasticity stiffness tensile Young’s modulus

On the truth of nanoscale for nanobeams based on nonlocal elastic stress field theory:equilibrium,governing equation and static deflection

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Applied Mathematics and Mechanics(English Edition) 2010年第1期31卷 37-54页

作者： c. W. lim Department of Building and construction City University of Hong Kong

This paper has successfully addressed three critical but overlooked issues in nonlocal elastic stress field theory for nanobeams：（i） why does the presence of increasing nonlocal effects induce reduced nanostructural stiffness in many, but not consistently for all, cases of study, i.e., increasing static deflection, decreasing natural frequency and decreasing buckling load, although physical intuition according to the nonlocal elasticity field theory first established by Eringen tells otherwise？（ii） the intriguing conclusion that nanoscale effects are missing in the solutions in many exemplary cases of study, e.g., bending deflection of a cantilever nanobeam with a point load at its tip; and （iii） the non-existence of additional higher-order boundary conditions for a higher-order governing differential equation. Applying the nonlocal elasticity field theory in nanomechanics and an exact variational principal approach, we derive the new equilibrium conditions, do- main governing differential equation and boundary conditions for bending of nanobeams. These equations and conditions involve essential higher-order differential terms which are opposite in sign with respect to the previously studies in the statics and dynamics of nonlocal nano-structures. The difference in higher-order terms results in reverse trends of nanoscale effects with respect to the conclusion of this paper. Effectively, this paper reports new equilibrium conditions, governing differential equation and boundary condi- tions and the true basic static responses for bending of nanobeams. It is also concluded that the widely accepted equilibrium conditions of nonlocal nanostructures are in fact not in equilibrium, but they can be made perfect should the nonlocal bending moment be replaced by an effective nonlocal bending moment. These conclusions are substantiated, in a general sense, by other approaches in nanostructural models such as strain gradient theory, modified couple stress models and experim

关键词： bending effective nonlocal bending moment nanobeam nanomechanics,nanoscale nonlocal elastic stress strain gradient

Asymptotic analysis of a vibrating cantilever with a nonlinear boundary

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Science china(Physics,Mechanics & Astronomy) 2009年第9期52卷 1414-1422页

作者： c. W. lim Department of Building and construction City University of Hong Kong

Nonlinear vibration of a cantilever in a contact atomic force microscope is analyzed via an asymptotic approach. The asymptotic solution is sought for a beam equation with a nonlinear boundary condition. The steady-state responses are determined in primary resonance and subharmonic resonance. The relations between the response amplitudes and the excitation frequencies and amplitudes are derived from the solvability condition. Multivaluedness occurs in the relations as a consequence of the nonlinearity. The stability of steady-state responses is analyzed by use of the Lyapunov linearized stability theory. The stability analysis predicts the jumping phenomenon for certain parameters. The curves of the response amplitudes changing with the excitation frequencies are numerically compared with those obtained via the method of multiple scales. The calculation results demonstrate that the two methods predict the same varying tendencies while there are small quantitative differences.

关键词： asymptotic analysis vibration nonlinear boundary condition beam contact