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Effects of ultrasonic-assisted extraction on bioactive compounds,volatile flavors and antioxidant activities of vine tea water extracts

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Traditional Medicine Research 2025年第1期10卷 73-81页

作者： Xiao-Long Zhou wei-Jin Jiang Ji Yu Mao-Jun Yao yun-Tong Li Hunan Provincial Key Laboratory of Research Resource Mining and High-valued Utilization on Edible&Medicinal PlantCollege of Chemistry and Chemical EngineeringJishou UniversityJishou 416000China Hunan Gaoge Dairy Co. Ltd.Changsha 410000China

Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in *** vine tea processing,a large amount of broken tea is produced,which has low commercial ***:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea ***:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid *** chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted ***,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE *** vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant ***:The findings suggest that extraction methods signi

关键词： vine tea dihydromyricetin ultrasonic-assisted extraction volatile aroma components

Master equation approach to transient quantum transport in nanostructures

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Frontiers of physics 2017年第4期12卷 43-78页

作者： Pei-yun yang wei-Min Zhang Department of Physics and Centre for Quantum Information Science Cheng Kung University Tainan 70101

In this review article, we present a non-equilibrium quantum transport theory for transient electron dynamics in nanodevices based on exact Master equation derived with the path integral method in the fermion coherent-state representation. Applying the exact Master equation to nanodevices, we also establish the connection of the reduced density matrix and the transient quantum transport current with the Keldysh nonequilibrium Green functions. The theory enables us to study transient quantum transport in nanostructures with back-reaction effects from the contacts, with non-Markovian dissipa- tion and decoherence being fully taken into account. In applications, we utilize the theory to specific quantum transport systems, a variety of quantum decoherence and quantum transport phenomena involving the non-Markovian memory effect are investigated in both transient and stationary scenarios at arbitrary initial temperatures of the contacts.

关键词： quantum transport Master equation open systems nanostructures

A new characterization of Willmore submanifolds

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Applied Mathematics(A Journal of Chinese Universities) 2011年第4期26卷 453-463页

作者： XU Hong-wei yang Deng-yun Center of Mathematical Sciences Zhejiang University Hangzhou 310027 China.

Let M^n be a compact Willmore submanifold in the unit sphere Sn＋p. In this note, we investigate the first eigenvalue of the SchrSdinger operator L = -△ - q on M, where q is some potential function on M, and present... 详细信息

关键词： Willmore submanifolds Schrodinger operator eigenvalue fiat normal bundle Willmore torus.

Revisiting the event rate of short GRBs and estimating their detectable number within the Advanced LIGO horizon

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Research in Astronomy and Astrophysics 2019年第8期19卷 123-130页

作者： Hao-yang Liu yun-wei Yu Institute of Astrophysics Central China Normal University

The redshift and luminosity distributions of 36 Swift short gamma-ray bursts(GRBs) are fitted by connecting their event rates with cosmic star formation rates using power-law distributed delay times f(τ) ∝τ-1, where a broken-power-law luminosity function is assumed and some empirical observational selection effects are taken into account. As a result, the most-likely model parameters are constrained to be ν1 = 0.91, ν2 = 1.66 as power-law indices, with a break at Lb= 2.51 × 1051 erg s-1 for the luminosity function and τc= 6.0 Gyr for a typical gravitational wave decay timescale of the binary orbit. The corresponding local rate of short GRBs is found to be 3-4 Gpc-3 yr-1. With these parameters, the detectable numbers of short GRBs are estimated within the horizon of Advanced LIGO.

关键词： gamma-ray burst:general luminosity function stars:neutron

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang Ju-yun Ma Peng-Peng Li Hai-wei Pu Xin-Yian Guo Jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

Validation of EMMS-based drag model using lattice Boltzmann simulations on GPUs

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Particuology 2011年第4期9卷 365-373页

作者： yun Zhang wei Ge Xiaowei Wang Chaohe yang State Key Laboratory of Heavy Oil Processing China University of Petroleum Qingdao 266555 China The EMMS Croup State Key Laboratory of Multi-phase Complex Systems Institute of Process Engineering Chinese Academy of Sciences Beijing 100190 China

lnterphase momentum transport in heterogeneous gas-solid systems with multi-scale structure is of great importance in process engineering. In this article, lattice Boltzmann simulations are performed on graphics processing units （GPUs）, the computational power of which exceeds that of CPUs by more than one order of magnitude, to investigate incompressible Newtonian flow in idealized multi-scale particle-fluid systems. The structure consists of a periodic array of clusters, each constructed by a bundle of cylinders. Fixed pressure boundary condition is implemented by applying a constant body force to the flow through the medium. The bounce-back scheme is adopted on the fluid-solid interfaces, which ensures the no-slip boundary condition. The structure is studied under a wide range of particle diameters and packing fractions, and the drag coefficient of the structure is found to be a function of voidages and fractions of the clusters, besides the traditional Reynolds number and the solid volume fractions. Parameters reflecting multi-scale characters are, therefore, demonstrated to be necessary in quantifying the drag force of heterogeneous gas-solid system. The numerical results in the range 0.1 〈 Re 〈 10 and 0 〈 Ф 〈 0.25 are compared with Wen and Yu＇s correlation, Gibilaro equation, EMMS-based drag model, the Beetstra correlation and the Benyahia correlation, and good agreement is found between the simulations and the EMMS-based drag model for heterogeneous systems.

关键词： EMMS Drag model Lattice Boltzmann method GPU

Novel synthesis of a strained para-cyclophane derivative

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Chinese Chemical Letters 2007年第4期18卷 397-399页

作者： Zhi Hao Shi yun yang wei Institute of Chemical Engineering Nanjing University of Science and Technology Nanjing 210094 China

A [P. Rajakumar, A.M.A. Rasheed, Tetrahedron 61（22）（2005） 5351] para-cyclophane derivative was synthesized via intramolecular esterification of a dipeptide surrogate containing asparagine to form tetrahydropyrimi... 详细信息

关键词： Asparagine Cyclization Para-cyclophane

Crowdsourcing intelligent design

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Frontiers of Information Technology & Electronic Engineering 2018年第1期19卷 126-138页

作者： wei XIANG Ling-yun SUN wei-tao YOU Chang-yuan yang State Key Lab of CAD & CG Zhejiang University Hangzhou 310058 China Modern Industrial Design Institute Zhejiang University Hangzhou 310027 China International User Experience Business Unit Alibaba Group Hangzhou 310000 China

Design intelligence,namely,artificial intelligence to solve creative problems and produce creative ideas,has improved rapidly with the new generation artificial ***,existing methods are more skillful in learning from data and have limitations in creating original ideas different from the training *** offers a promising method to produce creative designs by combining human inspiration and machines' computational *** propose a crowdsourcing intelligent design method called ‘flexible crowdsourcing design'.Design ideas produced through crowdsourcing design can be unreliable and inconsistent because they rely solely on selection among participants' submissions of *** contrast,the flexible crowdsourcing design method employs a cultivation procedure that integrates the ideas from crowd participants and cultivates these ideas to improve design quality at the same *** introduce a series of studies to show how flexible crowdsourcing design can produce original design ideas ***,we will describe the typical procedure of flexible crowdsourcing design,the refined crowdsourcing tasks,the factors that affect the idea development process,the method for calculating idea development potential,and two applications of the flexible crowdsourcing design ***,it summarizes the design capabilities enabled by crowdsourcing intelligent *** method enhances the performance of crowdsourcing design and supports the development of design intelligence.

关键词： Crowdsourcing Flexible crowdsourcing design Design intelligence

Emergency response facility location in transportation networks: A literature review

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Journal of Traffic and Transportation Engineering(English Edition) 2021年第2期8卷 153-169页

作者： yang Liu yun Yuan Jieyi Shen wei Gao College of Artificial Intelligence Nanjing Agricultural UniversityNanjing 210031China College of Transportation Engineering Dalian Maritime UniversityDalian 116026China College of Engineering University of UtahSalt Lake CityUT 84112USA

Emergency response activity relies on transportation networks. Emergency facility location interacts with transportation networks clearly. This review is aimed to provide a combined framework for emergency facility location in transportation networks. The article reveals emergency response activities research clusters, issues, and objectives according to keywords co-occurrence analysis. Four classes of spatial separation models in transportation networks, including distance, routing, accessibility, and travel time are introduced. The stochastic and time-dependent characteristics of travel time are described. Travel time estimation and prediction method, travel time under emergency vehicle preemption,transportation network equilibrium method, and travel time in degradable networks are demonstrated. The emergency facilities location models interact with transportation networks, involving location-routing model, location models embedded with accessibility,location models embedded with travel time, and location models employing mathematical program with equilibrium constraints are reviewed. We then point out the-state-of-art challenges: ilities-oriented, evolution landscape and sequential decision modelling, datadriven optimization approach, and machine learning-based algorithms.

关键词： Transportation engineering Emergency facility location Transportation networks Travel time Machine learning

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