检索结果-南通市图书馆

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德国纽伦堡医院儿科护理学习见闻与启示

护理研究 2018年第21期32卷 3484-3486页

作者：陈丽莲深圳市妇幼保健院

介绍了笔者在德国纽伦堡医院进修学习时的见闻,包括德国的医保制度、护士培养模式、纽伦堡医院儿科的护理理念、护士管理以及临床护理模式等,为国内的护理工作开辟新思路。

关键词：儿科护理德国纽伦堡医院护理管理医保制度护士培养模式学习见闻

IMpower210:A phase Ⅲ study of second-line atezolizumab vs. docetaxel in East Asian patients with non-small cell lung cancer

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Chinese Journal of Cancer Research 2024年第2期36卷 103-113页

作者： Yi-Long Wu Shun Lu Gongyan chen Jianxing He Jifeng Feng Yiping Zhang Liyan Jiang Hongming Pan Jianhua Chang Jian Fang Amy Cai lilian Bu Jane Shi Jinjing Xia Guangdong Lung Cancer Institute Guangdong Provincial Key Laboratory of Translational Medicine in Lung CancerGuangdong Provincial People's Hospital&Guangdong Academy of Medical SciencesSouthern Medical UniversityGuangzhou 510080China Shanghai Lung Cancer Center Shanghai Chest HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200025China Department of Respiration Harbin Cancer HospitalHarbin Medical UniversityHarbin 150081China Department of Thoracic Oncology and Surgery the First Affliated Hospital of Guangzhou Medical UniversityGuangzhou 510120China Department of Medical Oncology Jiangsu Cancer HospitalNanjing 210009China Department of Medical Oncology Zhejiang Cancer HospitalHangzhou 330022China Department of Pulmonary Medicine Shanghai Chest HospitalShanghai Jiao Tong UniversityShanghai 200030China Department of Medical Oncology Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Department of Medical Oncology Shenzhen HospitalCancer Hospital of Chinese Academy of Medical SciencesShenzhen 518116China Department of Thoracic Oncology Beijing Cancer HospitalBeijing 100142China Product Development Shanghai Roche Pharmaceutical LtdShanghai 201203China

Objective: IMpower210(NCT02813785) explored the efficacy and safety of single-agent atezolizumab *** as second-line treatment for advanced non-small cell lung cancer(NSCLC) in East Asian ***: Key eligibility criteria for this phase Ⅲ, open-label, randomized study included age ≥18 years;histologically documented advanced NSCLC per the Union for International Cancer Control/American Joint Committee on Cancer staging system(7th edition);Eastern Cooperative Oncology Group performance status of 0 or 1;and disease progression following platinum-based chemotherapy for advanced or metastatic NSCLC. Patients were randomized 2:1 to receive either atezolizumab(1,200 mg) or docetaxel(75 mg/m^(2)). The primary study endpoint was overall survival(OS) in the intention-to-treat(ITT) population with wild-type epidermal growth factor receptor expression(ITT EGFR-WT) and in the overall ITT ***: Median OS in the ITT EGFR-WT population(n=467) was 12.3 [95% confidence interval(95% CI),10.3-13.8] months in the atezolizumab arm(n=312) and 9.9(95% CI, 7.8-13.9) months in the docetaxel arm[n=155;stratified hazard ratio(HR), 0.82;95% CI, 0.66-1.03]. Median OS in the overall ITT population was 12.5(95% CI, 10.8-13.8) months with atezolizumab treatment and 11.1(95% CI, 8.4-14.2) months(n=377) with docetaxel treatment(n=188;stratified HR, 0.87;95% CI, 0.71-1.08). Grade 3/4 treatment-related adverse events(TRAEs) occurred in 18.4% of patients in the atezolizumab arm and 50.0% of patients in the docetaxel ***: IMpower210 did not meet its primary efficacy endpoint of OS in the ITT EGFR-WT or overall ITT populations. Atezolizumab was comparatively more tolerable than docetaxel, with a lower incidence of grade3/4 TRAEs.

关键词： Atezolizumab East Asia non-small cell lung cancer programmed death-ligand 1 inhibitors monoclonal antibody

惠安女服饰文化的衰微与保护初探——以小岞惠安女服饰为例

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武夷学院学报 2018年第1期37卷 63-68页

作者：陈丽恋黎明职业大学图书馆福建泉州362000

惠安女因其独特的服饰而闻名海内外,然而在现代化进程中,惠安女服饰文化的传承面临着断层危机。小岞惠安女服饰作为惠女服饰的一支,以艳丽而不失古朴的韵味散发着浓郁的地域气息,通过其发型、头饰、服饰的色彩款式,布料材质以及用途功... 详细信息

惠安女因其独特的服饰而闻名海内外,然而在现代化进程中,惠安女服饰文化的传承面临着断层危机。小岞惠安女服饰作为惠女服饰的一支,以艳丽而不失古朴的韵味散发着浓郁的地域气息,通过其发型、头饰、服饰的色彩款式,布料材质以及用途功能等历史演变情况的阐述;从传统工艺流失、文化认知偏颇和相关史料缺失方面指出惠女服饰走向衰微的原因;提出加强惠女服饰保护、宣传、创新和数字化建设的对策和建议,呼吁各界重视保护和传承惠安女服饰文化。

关键词：小岞惠安女服饰文化传承保护

新媒介下高校对惠女编织腰带活态传承及传播利用探究

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武夷学院学报 2021年第4期40卷 52-57页

作者：陈丽恋黎明职业大学图书馆福建泉州362000

很多优秀的传统技艺、文化,由于受时间和空间的限制,外界无法领略到它们独有的魅力和精髓,加之新时代大环境的不断变化,这些优秀文化(如惠女编织腰带)经受了巨大的冲击,已面临着消失的困境。立足本土高校,通过对惠女编织腰带技艺、文化... 详细信息

很多优秀的传统技艺、文化,由于受时间和空间的限制,外界无法领略到它们独有的魅力和精髓,加之新时代大环境的不断变化,这些优秀文化(如惠女编织腰带)经受了巨大的冲击,已面临着消失的困境。立足本土高校,通过对惠女编织腰带技艺、文化现状的梳理,分析高校传承地方优秀文化的优势和意义;运用多种形式对编织腰带进行“活态”传承及改良创新,积极探究新媒介传播和“活用”传统文化(腰带编织技艺文化)的策略方式,希望为编织腰带在新时期的传承和发展提供新的生机和动力,同时促进和推动中华文化软实力的发展。

关键词：新媒介编织腰带活态传承文化传播

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高校图书馆藏书丢失损毁状况及对策

黎明职业大学学报 2008年第2期 73-77页

作者：陈丽恋黎明职业大学图书馆福建泉州362000

揭示了高校图书馆藏书丢失损毁现象的严重性,对高校学生在图书馆借阅中存在的偷书、污损图书以及撕毁图书等不良行为进行阐述,对读者的不良阅读心理原因和图书馆制度不完善、管理不规范进行了分析,并就此情况提出了加强教育宣传、建立... 详细信息

揭示了高校图书馆藏书丢失损毁现象的严重性,对高校学生在图书馆借阅中存在的偷书、污损图书以及撕毁图书等不良行为进行阐述,对读者的不良阅读心理原因和图书馆制度不完善、管理不规范进行了分析,并就此情况提出了加强教育宣传、建立图书质量状况核对制度、完善图书损毁丢失的赔偿制度等若干对策和建议。

关键词：高校图书馆学生阅读心理

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基于数学核心素养的“深度学习”教学实践

当代教研论丛 2020年第12期7卷 20-20,22页

作者：陈立廉福建省莆田市秀屿区第三实验小学福建莆田351100

随着课程标准的改革,学校各学科教学模式也做出相应调整。如何帮助小学生更好地理解数学这门课程,从而建立起长远的研究兴趣是当今教师要慎重思考的问题。本文针对数学核心素养下"深度学习"教学实践进行深入研究。

关键词：数学核心素养深度学习教学

泉州高校图书馆助力本土渔女服饰文化传承的探究

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黎明职业大学学报 2021年第1期 34-38,44页

作者：陈丽恋黎明职业大学图书馆福建泉州362000

惠安女服饰、蟳埔女服饰是泉州市重要的非物质文化遗产,地方高校图书馆在推进本土渔女服饰文化传承工作中,要实现文化传播与育人的融合,在乡土人文教育、服饰技艺传承与美育、“海丝”人才素质培养方面把握好方向。通过黎明职业大学图... 详细信息

惠安女服饰、蟳埔女服饰是泉州市重要的非物质文化遗产,地方高校图书馆在推进本土渔女服饰文化传承工作中,要实现文化传播与育人的融合,在乡土人文教育、服饰技艺传承与美育、“海丝”人才素质培养方面把握好方向。通过黎明职业大学图书馆的工作实例,阐明地方高校图书馆如何助力本土渔女服饰文化传承:构建知识信息港、实践教育、海丝文化活动等传承载体;大力推进数字化保护与传承,为本土渔女服饰文化建档立库,以此生成教育活动、文化活动的重要资源。

关键词：渔女服饰文化高校图书馆 “非遗”传承泉州市

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创建高校图书馆休闲文化服务的探讨

情报探索 2016年第4期 111-113页

作者：陈丽恋黎明职业大学图书馆福建泉州362000

[目的/意义]创建高校图书馆休闲文化服务,对高校营造健康休闲环境有重要意义。[方法/过程]阐述了创建高校图书馆休闲文化服务的必要性,以黎明职业大学图书馆为例,探讨了图书馆营造休闲环境、开展形式多样休闲服务的具体措施。[结果/结论... 详细信息

[目的/意义]创建高校图书馆休闲文化服务,对高校营造健康休闲环境有重要意义。[方法/过程]阐述了创建高校图书馆休闲文化服务的必要性,以黎明职业大学图书馆为例,探讨了图书馆营造休闲环境、开展形式多样休闲服务的具体措施。[结果/结论]创建高校图书馆休闲文化服务可以增强图书馆对学生吸引力,提高文献资源利用率,促进读者健康休闲娱乐养成,体现图书馆人文关怀。

关键词：高校图书馆大学生休闲文化图书馆服务

维普期刊数据库博看期刊

A Cost-Utility Analysis Comparing Oncoplastic Breast Surgery to Standard Lumpectomy in Large Breasted Women

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Advances in Breast Cancer Research 2018年第2期7卷 187-200页

作者： Abhishek Chatterjee Anaeze C. Offodile II Ammar Asban Raquel A. Minasian Albert Losken Roger Graham lilian chen Brian J. Czerniecki Carla Fisher Department of Surgery Tufts University Medical Center Boston MA USA Johns Hopkins Bloomberg School of Public Health Baltimore MD USA Department of Surgery University of Alabama at Birmingham Birmingham AL USA Division of Plastic and Reconstructive Surgery Department of Surgery Emory University School of Medicine Atlanta GA USA Department of Breast Oncology H Lee Moffitt Cancer Center Tampa FL USA Department of Surgery University of Pennsylvania Philadelphia PA USA

Purpose: Ablative options, beyond mastectomy, for large breasted patients with breast cancer include oncoplastic resection via reduction pattern and standard lumpectomy. Oncoplastic resection also entails a contralateral procedure for symmetry and the potential benefit of a superior cosmetic outcome. Our aim was to examine the cost-effectiveness of this treatment strategy comparing it to standard lumpectomy in treating breast cancer patients. Methods: A literature review was performed of the probabilities and outcomes related to treatment of unilateral breast cancer via oncoplastic resection or unilateral lumpectomy. Utility score surveys were used to estimate the quality adjusted life years (QALYs) associated with a successful procedure, additional margins excision and post-operative complications. A decision analysis tree was developed to highlight the more cost-effective strategy. An Incremental Cost-Utility Ratio (ICUR) was calculated. Sensitivity analysis was performed to check the robustness of our data. Results: Oncoplastic resection was associated with fewer positive margins relative to standard lumpectomy (10.0% versus 18%). In cases with positive margins, a greater percentage of oncoplastic resection patients chose a mastectomy compared to the lumpectomy patients (72% versus 19%). Utility scores for a successful operation favored oncoplastic resection (92.6 versus 86.55), but in instances of positive margins, favored the lumpectomy patients (74.2 versus 70.2). Decision tree analysis revealed that oncoplastic resection was more cost-effective with an ICUR of $2609.66/QALY gained. Conclusion: Oncoplastic resection represents a cost-effective strategy for the large breasted patient and provides the surgical team yet another reasonable option for the appropriate patient.

关键词： Breast Cancer Lumpectomy Mastectomy Cost-Utility Analysis