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Stellerite-seeded facile synthesis of zeolite X with excellent aqueous Cd^(2+)and Ni^(2+)adsorption performance

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Chinese Journal of Chemical Engineering 2022年第11期51卷 61-74页

作者： Yinchang Pei Shengpeng Mo Qinglin Xie Nanchun Chen Zhongxin Yang lili huang lili Ma College of Environmental Science and Engineering Guilin University of TechnologyGuilin 541006China Collaborative Innovation Center for Water Pollution Control and Water Safety in Karst Area Guilin University of TechnologyGuilin 541006China College of Material Science and Engineering Guilin University of TechnologyGuilin 541006China

Zeolite X was synthesized by a two-step hydrothermal method using natural stellerite zeolite as the silicon seed,and its adsorption performance for Cd^(2+)and Ni^(2+)ions was experimentally and comprehensively *** effects of p H,zeolite X dosage,contact time,and temperature on adsorption performance for Cd^(2+)and Ni^(2+)ions over were *** adsorption process was endothermic and spontaneous,and followed the pseudo-second-order kinetic and the Langmuir isotherm *** maximum adsorption capacitiesfor Cd^(2+)and Ni^(2+)ions at 298 K were 173.553 and 75.897 mg.g-1,*** exchange and precipitation were the principal mechanisms for the removal of Cd^(2+)ions from aqueous solutions by zeolite X,followed by electrostatic *** exchange was the principal mechanisms for the removal of Ni^(2+)ions from aqueous solutions by zeolite X,followed by electrostatic adsorption and *** zeolite X converted from stellerite zeolite has a low n(Si/Al),abundant hydroxyl groups,and high crystallinity and purity,imparting a good adsorption performance for Cd^(2+)and Ni^(2+)*** study suggests that zeolite X converted from stellerite zeolite could be a useful environmentally-friendly and effective tool for the removal of Cd^(2+)and Ni^(2+)ions from aqueous solutions.

关键词： Zeolite X Stellerite zeolite Adsorption mechanism Cd^(2+)adsorption Ni^(2+)adsorption Ion exchange

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Learning deep representations for semantic image parsing： a comprehensive overview

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Frontiers of Computer Science 2018年第5期12卷 840-857页

作者： lili huang Jiefeng PENG Ruimao ZHANG Guanbin LI Liang LIN School of Data and Computer Science Sun Yat-sen University Guangzhou 510006 China

Semantic image parsing, which refers to the pro- cess of decomposing images into semantic regions and constructing the structure representation of the input, has re- cently aroused widespread interest in the field of computer vision. The recent application of deep representation learning has driven this field into a new stage of development. In this paper, we summarize three aspects of the progress of research on semantic image parsing, i.e., category-level semantic segmentation, instance-level semantic segmentation, and beyond segmentation. Specifically, we first review the general frameworks for each task and introduce the relevant variants. The advantages and limitations of each method are also discussed. Moreover, we present a comprehensive comparison of different benchmark datasets and evaluation metrics. Finally, we explore the future trends and challenges of semantic image parsing.

关键词： semantic image segmentation deep learning onvolutional neural networks image parsing

Investigation on P-Glycoprotein Function and Its Interacting Proteins under Simulated Microgravity

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Space(Science & Technology) 2021年第1期2021卷 195-207页

作者： Yujuan Li lili huang Javed Iqbal Yulin Deng School of Life Sciences Beijing Institute of TechnologyBeijing 100081China Department of Biology Government College MankeraUniversity of SargodhaSargodhaPakistan

P-glycoprotein(P-gp)could maintain stability of the nerve system by effluxing toxins out of the blood-brain *** it plays a very important role in drug brain distribution during space travel is not yet *** present study was aimed at investigating P-gp function,expression,and its interacting proteins in a rat brain under simulated microgravity(SMG)by comparative proteomics *** were tail-suspended to induce short-(7-day)and long-term(21-day)microgravity.P-gp function was assessed by measuring the P-gp ATPase activity and the brain-to-plasma concentration ratio of rhodamine 123.P-gp expression was evaluated by Western blot.21d-SMG significantly enhanced P-gp efflux activity and expression in ***-free proteomics strategy identified 26 common differentially expressed proteins(DEPs)interacting with P-gp in 7d-and 21d-SMG *** of the DEPs mainly regulated ATP hydrolysis coupled transmembrane transport and so *** analysis showed that P-gp might potentially interact with heat shock proteins,sodium/potassium ATP enzyme,ATP synthase,microtubule-associated proteins,and vesicle fusion *** present study firstly reported P-gp function,expression,and its potentially interacting proteins exposed to simulated *** findings might be helpful not only for further study on nerve system stability but also for the safe and effective use of P-gp substrate drugs during space travel.

关键词： drugs travel maintain

Plasmon-enhanced broad-band quantum-cutting of NaBaPO4:Eu^2+,Er^3+phosphors with silver nano-particles

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Journal of Rare Earths 2020年第11期38卷 1151-1157,I0001页

作者： Jinquan Hong Lin Lin Xiaoyan Li Zhuohong Feng lili huang Qing Qin Zhiqiang Zheng College of Physics and Energy Fujian Normal UniversityFuzhou 350117China Department of Physics and Electronic Information Engineering Minjiang UniversityFuzhou 350121China Fujian Provincial Collaborative Innovation Center for Optoelectronic Semiconductors and Efficient Devices Xiamen 361005China

NaBaPO4:Eu^2+,Er^3+phosphors and Ag nano-particles(NPs)were prepared by the solid-state reaction and chemical reduction method,*** fluorescence spectra and decay curves demonstrate the effective energy transfer from Eu^2+to Er^3+and the existence of three-photon quantum-cutting through two-step cross-relaxation of Er^3+.The quantum-cutting emission is peaked at 1534 nm with a broad excitation band centered at 352 nm,Plasmon-enhanced quantum-cutting of NaBaPO4:Eu^2+,Er^3+phosphors was realized by decorating Ag *** largest enhancement factor is *** is hopeful to improve the photovoltaic conversion efficiency of Ge solar cells by using this phosphor.

关键词： Luminescence Localized surface plasmon resonance Broad-band quantum-cutting Rare-earth doped phosphors

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Characteristic Investigation of Nano-Crystal Hydrogen Storage Alloys

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Journal of Rare Earths 2004年第z1期22卷 232-234页

作者： Xiao Fangming huang lili Tang Renheng Lu Qiyun Peng Neng Wang Ying Rare Earth Materials Research Center Guangzhou Research Institute of Nonferrous Metals Guangzhou 510651 China

A Ml (NiCoMnA1)5 hydrogen storage alloys was prepared by double-roller rapid *** microstructure, electrochemically and kinetic characteristic were studied.A uniform crystal phase with CaCu5 structure could be detected by XRD analyses, whose average grain size is 30 ~ 50 nm and the ratio of c/a of nano-crystal hydrogen storage alloy is *** hydrogen absorption/desertion p - C isotherms of alloy show that its fiat-performance is perfect and the magnetic stagnant effect is very *** simulate cell is used for electrochemical *** is 10C, the capacity decreasing rate via the 450 cycles at 7C is less than 20%.

关键词： nano-crystal hydrogen storage alloys electrochemically characteristic

Microstructure improvement related coercivity enhancement for sintered NdFeB magnets after optimized additional heat treatment

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Journal of Rare Earths 2018年第4期36卷 379-384页

作者： Qing Zhou Wei Li Yuan Hong Lizhong Zhao Xichun Zhong Hongya Yu lili huang Zhongwu Liu School of Materials Science and Engineering South China University of TechnologyGuangzhou 510640China Guangdong Research Institute of Rare Metals Guangzhou 510651China

The micro structure, especially the Nd-rich phase and the grain boundary, in sintered NdFeB magnets plays an important role in magnetic reversal and coercivity mechanism. To better understand the effects of the microstructure on the coercivity, we investigated the microstructure and properties improvements of a commercial sintered NdFeB magnet after optimized additional heat treatment. The coercivity is enhanced from 1399 to 1560 kA/m. This enhancement has been explained in terms of the evolution of the grain boundary structure, and the formation of continuous thin layers of Nd-rich phase is important for high coercivity. The micromagnetic simulation together with the numerical analysis based on the nucleation model suggest that the reversed magnetic domains nucleate mainly at the interface of multijunctions of Nd_2 Fe_（14）B grains with high stray fields during the demagnetization process. Both improved anisotropy fields at grain boundaries and reduced stray fields at multi-junction Nd-rich phases contribute to the coercivity enhancement. This work has importance in understanding the crucial micro structure parameters and enhancing the obtainable properties for sintered NdFeB magnets.

关键词： Sintered NdFeB magnets Microstructure Coercivity Micromagnetic simulation Heat treatment Rare earths

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Molecular mechanisms of cisplatin resistance in ovarian cancer

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Genes & Diseases 2024年第6期11卷 221-236页

作者： Chenying Jiang Chenjun Shen Maowei Ni lili huang Hongtao Hu Qinhui Dai Huajun Zhao Zhihui Zhu School of Pharmaceutical Sciences Zhejiang Chinese Medical UniversityHangzhouZhejiang 311402China The Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital) Institute of Basic Medicine and Cancer(IBMC)Chinese Academy of SciencesHangzhouZhejiang 310005China

Ovarian cancer is one of the most common malignant tumors of the female repro-ductive *** majority of patients with advanced ovarian cancer are mainly treated with cisplatin-based *** the most widely used first-line anti-neoplastic drug,cisplatin produces therapeutic effects through multiple ***,during clinical treat-ment,cisplatin resistance has gradually emerged,representing a challenge for patient outcome *** mechanism of cisplatin resistance,while known to be complex and involve many processes,remains *** hope to provide a new direction for pre-clin-ical and clinical studies through this review on the mechanism of ovarian cancer cisplatin resis-tance and methods to overcome drug resistance.

关键词： Cisplatin Drug resistance Molecular mechanisms Ovarian cancer Therapeutic strategies

Engineering SIRPα cellular membrane-based nanovesicles for combination immunotherapy

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Nano Research 2023年第5期16卷 7355-7363页

作者： Mingyue Wang Yanfang Wang Yeteng Mu Fuxu Yang Zebin Yang Yuxuan Liu lili huang Shi Liu Xingang Guan Zhigang Xie Zhen Gu School of Medicine Taizhou UniversityTaizhou 318000China College of Medical Technology Beihua UniversityJilin 132013China Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Jinhua Institute of Zhejiang University Jinhua 321299China State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China Department of General Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016China Zhejiang Laboratory of Systems&Precision Medicine Zhejiang University Medical CenterHangzhou 311121China MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310027China

Immune checkpoint inhibitors(ICIs)have revolutionized cancer treatment for their unprecedented clinical *** regulatory proteinα(SIRPα)is a phagocytic checkpoint expressed on macrophages,dendritic cells,other myeloid *** cells inhibit macrophage phagocytosis through the interaction of the CD47-SIRPα*** the CD47-SIRPαaxis has therefore been a promising strategy in restoring the immune attack against ***,we engineered cellular membrane nanovesicles(NVs)presenting SIRPαreceptors for phagocytosis checkpoint blockade to augment the antitumor immune ***,zebularine(Zeb),an inhibitor of DNA methyltransferase,was encapsulated into SIRPαNVs to reprogram the immunosuppressive tumor microenvironment together with blockade of phagocytosis *** is demonstrated that SIRPα@Zeb can improve tumor immunogenicity,the polarization of tumor-associated macrophages to the M1 phenotype,increase the infiltration of CD8^(+)T lymphocytes in *** robust antitumor immune response induced by SIRPα@Zeb significantly suppressed tumor growth and extended mice-bearing melanoma xenograft survival.

关键词： drug delivery signal regulatory proteinα nanovesicle tumor-associated macrophages cancer immunotherapy

Two NIS1-like proteins from apple canker pathogen(Valsa mali)play distinct roles in plant recognition and pathogen virulence

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Stress Biology 2022年第1期2卷 606-620页

作者： Jiajun Nie Wenjing Zhou Yonghui Lin Zhaoyang Liu Zhiyuan Yin lili huang State Key Laboratory of Crop Stress Biology for Arid Areas College of Plant ProtectionNorthwest A&F University3 Taicheng RoadYangling 712100ShaanxiChina College of Plant Protection China Agricultural UniversityBeijing 100193China

Conserved effectors produced by phytopathogens play critical roles in plant-microbe ***1-like proteins represent a newly identified family of effectors distributed in multiple fungal ***,their biological functions in a majority of pathogenic fungi remain largely elusive and require further *** this study,we characterized two NIS1-like proteins VmNIS1 and VmNIS2 from Valsa mali,the causal agent of apple Valsa *** of these two proteins were predicted to be *** agroinfiltration,we found that VmNIS1 induced intense cell death,whereas VmNIS2 suppressed INF1 elicitin-triggered cell death in Nicotiana *** of *** with VmNIS1 recombinant protein produced by Escherichia coli activated a series of immune responses and enhanced plant disease resistance against Phytophthora *** contrast,VmNIS2 suppressed plant immune responses and promoted *** infection when transiently expressed in *** VmNIS1 and VmNIS2 were shown to be highly induced at late stage of *** *** individually knocking out of these two genes in ***,however,only VmNIS2 was shown to be required for pathogen virulence as well as tolerance to oxidative ***,we further showed that C-terminal extension of VmNIS1 was essential for plant recognition and VmNIS2 may escape plant detection via sequence *** data collectively indicate that VmNIS1 and VmNIS2 play distinct roles in plant recognition and pathogen virulence,which provided new insights into the function of NIS1-like proteins in plant-microbe interactions.

关键词： Valsa mali Effector protein Cell death Plant immunity Virulence