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Benefit of aerosol reduction to winter wheat during China's clean air action:A case study of Henan Province

Journal of Environmental Sciences 2024年第7期141卷 90-101页

作者： Yang Bai Pengfei Zhao Xueyang Chen lijun wang Wenjuan Chang Jianzhong Guo Jiayao wang College of Geography and Environmental Science Henan UniversityKaifeng 475004China Henan Industrial Technology Academy of Spatio-Temporal Big Data Henan UniversityZhengzhou 475000China Henan Technology Innovation Center of Spatio-Temporal Big Data Henan UniversityZhengzhou 450046China Key Laboratory of Geospatial Technology for the Middle and Lower Yellow River Regions(Henan University) Ministry of EducationKaifeng 475000China

A strongly declining aerosol radiative effect has been observed in China since 2013 after implementing the clean air action,yet its impact on wheat(Triticum aestivum L.)production remains *** use satellite measures and a biophysical crop model to assess the impact of aerosol-induced radiative perturbations on winter wheat production in the agricultural belt of Henan province from 2013 to *** calibrating parameters with the extended Fourier Amplitude Sensitivity Test(EFAST)and the generalized likelihood uncertainty estimation(GLUE)method,the DSSAT CERES-Wheat model was able to simulate crop biomass and yield more *** found that the aerosol negatively impacted wheat biomass by 21.87%and yield by 22.48%from 2006 to 2018,and the biomass effects from planting to anthesis were more significant compared to anthesis to *** to the strict clean air action,under all-sky conditions,the surface solar shortwave radiation(SSR)in 2018 increased by about 7.08%over 2006-2013 during the wheat growing *** a result of the improvement of crop photosynthesis,winter wheat biomass and yield increased by an average of 5.46%and 2.9%,*** findings show that crop carbon uptake and yield will benefit from the clean air action in China,helping to ensure national food and health security.

关键词： Haze pollution Clean air action Aerosol-induced radiative perturbation Wheat production DSSAT model

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Cryptococcus splenic abscess in primary biliary cholangitis: a case report

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World Journal of Emergency Medicine 2024年第4期15卷 319-321页

作者： Yuxin Dong Qing Tang lijun wang Songtao Shou Department of Emergency Medicine Tianjin Medical University General HospitalTianjin 300052China

Chronic liver diseases,including primary biliary cholangitis(PBC),are recognized as immunosuppressive conditions due to the impaired functionality of hepatic sinusoidal Kupffer cells.[1]PBC is specifically characterized by cholangitis and progressive liver pathology,which may eventually lead to *** compromised liver function and reduced efficacy of Kupffer cells in patients with PBC weaken their cell-mediated immune responses,increasing their susceptibility to opportunistic pathogens such as Cryptococcus.[2]Cryptococcosis is an infectious disease caused by pathogenic encapsulated yeasts of the genus Cryptococcus,which is distributed worldwide and exhibits diverse clinical presentations.[3]Most case reports on cryptococcal infections are associated with HIV infection or other conditions that compromise the immune system.[4]Case reports related to primary biliary cholangitis are ***,this case report underscores a rare cryptococcal infection in a patient with primary biliary cholangitis,emphasizing the need to consider opportunistic infections in those with compromised liver function and immune dysregulation.

关键词： cholangitis impaired diseases

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Mitochondrial genomes of Tapes dorsatus and Cardita variegata:insights into Heteroconchia phylogeny

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Journal of Oceanology and Limnology 2024年第3期42卷 943-959页

作者： Xumin wang Hua ZHANG Xindong TENG Wenhui SUN Zhikai XING Shuang wang Xiumei LIU Jiangyong QU lijun wang College of Life Science Yantai UniversityYantai 264005China Qingdao International Travel Healthcare Center Qingdao 266071China

Heteroconchia,a widespread and abundant aquatic invertebrate,is an important clade of bivalve *** relationship between the three branches of Heteroconchia,Palaeoheterodonta,Archiheterodonta,and Euheterodonta has become a main controversy in molecular studies of the relationships between *** the present study,we assembled the complete mitochondrial genomes of Tapes dorsatus(Veneridae)and Cardita variegata(Carditidae)using high-throughput *** is the first mitochondrial genome belonging to the family Carditidae to be *** used 12 protein coding genes(excluding atp8)from the complete mitochondrial genomes of 146 species to recover the internal relationships of *** results support the traditional view of early branching of Palaeoheterodonta and the recovery of the monophyly of Palaeoheterodonta,Anomalodesmata,*** analysis show that gene arrangement within Venerida was highly ***-calibrated phylogenetic studies based on a relaxed molecular clock model suggested that Veneridae originated approximately 337.62 million years ago(Ma)and split into two major clades,whereas Carditidae originated approximately 510.09 *** results provide evidence of the internal relationships of Heteroconchia.

关键词： Tapes dorsatus Cardita variegata mitochondrial genome phylogeny

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The landscape of epigenetic regulation and therapeutic application of N^(6)-methyladenosine modifications in non-coding RNAs

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Genes & Diseases 2024年第5期11卷 236-251页

作者： Gui-e Xu Xuan Zhao Guoping Li Priyanka Gokulnath lijun wang Junjie Xiao Institute of Geriatrics(Shanghai University) Affiliated Nantong Hospital of Shanghai University(The Sixth People’s Hospital of Nantong)and School of Life SciencesShanghai UniversityNantongJiangsu 226011China Cardiac Regeneration and Ageing Lab Institute of Cardiovascular SciencesShanghai Engineering Research Center of Organ RepairSchool of Life ScienceShanghai UniversityShanghai 200444China Cardiovascular Division of the Massachusetts General Hospital and Harvard Medical School BostonMA 02114USA

RNA N^(6)-methyladenosine(m^(6)A)methylation is the most abundant and conserved RNA modification in *** participates in the regulation of RNA metabolism and various pathophysiological ***-coding RNAs(ncRNAs)are defined as small or long transcripts which do not encode proteins and display numerous biological regulatory *** to mRNAs,m^(6)A deposition is observed in *** RNA m^(6)A modifications on ncRNAs is of great importance specifically to deepen our understanding of their biological roles and clinical *** this review,we summarized the recent research findings regarding the mutual regulation between RNA m^(6)A modification and ncRNAs(with a specific focus on microRNAs,long non-coding RNAs,and circular RNAs)and their *** also discussed the challenges of m^(6)A-containing ncRNAs and RNA m^(6)A as therapeutic targets in human diseases and their future perspective in translational roles.

关键词： Circular RNA Epigenetic regulation Long non-coding RNA MicroRNA Non-coding RNA RNA m^(6)A modification

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Gene characterization and phylogenetic analysis of four mitochondrial genomes in Caenogastropoda

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Acta Oceanologica Sinica 2024年第2期43卷 137-150页

作者： Jiangyong Qu Wanqi Yang Xindong Teng Li Xu Dachuan Zhang Zhikai Xing Shuang wang Xiumei Liu lijun wang Xumin wang College of Life Science Yantai UniversityYantai 264005China Qingdao International Travel Healthcare Center Qingdao 266071China Qingdao Dagang Customs Qingdao 266071China

Caenogastropoda is a highly diverse group,containing~60%of all existing *** in this subclass predominantly inhabit marine environments and have a high ecological and economic *** to the increase in relevant phylogenetic studies,our understanding of between species relatedness in Caenogastropoda has ***,the biodiversity,taxonomic status,and phylogenetic relationships of this group remain *** the present study,we performed next-generation sequencing of four complete mitochondrial genomes from three families(Buccinidae,Columbellidae,and Cypraeidae)and the four mitogenomes were classical circular structures,with a length of 16177 bp in Volutharpa ampullacea,16244 bp in Mitrella albuginosa,16926bp in Mauritia arabica asiatica and 15422 bp in Erronea *** composition analysis indicated that whole sequences were biased toward A and *** compared them with 171 complete mitochondrial genomes of *** phylogenetic relationship of Caenogastropoda derived from Maximum Likelihood(ML)and Bayesian Inference(BI)trees constructed based on CDS sequences was consistent with the results of traditional morphological analysis,with all three families showing close *** study supported Caenogastropoda at the molecular level as a separate clade of *** to our divergence time estimations,Caenogastropoda was formed during the middle Triassic period(~247.2–237 Ma).Our novel mitochondrial genomes provide evidence for the speciation of Caenogastropoda in addition to elucidating the mitochondrial genomic evolution of this subclass.

关键词： mitochondrial genome phylogenetic analysis Caenogastropoda

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Progress in the diagnosis and treatment of graft fibrosis after liver transplantation

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Portal Hypertension & Cirrhosis 2024年第1期3卷 22-30页

作者： Youwei Zhao lijun wang Man Xie Wei Rao Department of Gastroenterology Medical College of Qingdao UniversityQingdaoShandongChina Department of Gastroenterology The Affiliated Hospital of Qingdao UniversityQingdaoShandongChina Division of Hepatology Liver Disease CenterThe Affiliated Hospital of Qingdao UniversityQingdaoShandongChina Department of Organ Transplantation Center The Affiliated Hospital of Qingdao UniversityQingdaoShandongChina

Liver transplantation(LT)is considered one of the best treatments for patients with end-stage liver ***,some patients with no significant clinical manifestations or abnormal laboratory tests still experience graft fibrosis during postoperative follow-up,which is often recognized by graft *** fibrosis can lead to graft dysfunction,thereby reducing the survival time of the recipient and even requiring ***,noninvasive methods are widely applied in the assessment of hepatic and allograft *** both noninvasive diagnostic models based on laboratory examination indicators and elastography technology that can quantify liver stiffness have some value in the evaluation of fibrosis,the diagnostic accuracy and characteristics of these various methods vary and cannot replace liver biopsy *** recent years,some liver-protective drugs and proprietary Chinese traditional medicines have been proven to delay or reverse chronic liver ***,their efficacy and safety for LT recipients need to be further *** article reviews the diagnosis and treatment of graft fibrosis after LT to provide a reference for improving the overall survival rate of LT recipients.

关键词： diagnosis fibrosis liver transplantation therapeutics

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MiR-30a-5p alleviates LPS-induced HPMEC injury through regulation of autophagy via Beclin-1

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BIOCELL 2024年第3期48卷 431-441页

作者： RAN PAN JIAYAN MAO YUELIANG ZHENG WEI CHEN JUNPING GUO lijun wang Rainbowfish Rehabilitation and Nursing School Hangzhou Vocational&Technical CollegeHangzhou310018China Cancer Institute of Integrated Traditional Chinese and Western Medicine Key Laboratory of Cancer Prevention and Therapy Combining Traditional Chinese and Western MedicineZhejiang Academy of Traditional Chinese MedicineHangzhou310012China Geriatric Medicine Center Department of EndocrinologyZhejiang Provincial People’s Hospital(Affiliated People’s Hospital)Hangzhou Medical CollegeHangzhou310015China

Background:Sepsis,a type of systemic disease,can impact nearly all organs,tissues and *** them,endothelial cells are amongst theﬁrst to be affected and respond to the *** this study,we investigated the protective effects of microRNA-30a-5p(miR-30a-5p)on human pulmonary microvascular endothelial cells(HPMECs)treated with lipolysaccharide(LPS).Methods:An in vitro model of sepsis was established in HPMECs with the use of *** with different tools(mimetic and inhibitor)to modify miR-30a-5p *** viability,proliferation and apoptosis were detected by the CCK-8 assay,the EdU kit andﬂuorescence staining,*** autophagy-related protein and mRNA expression,the number of autophagosomes were separately examined through Western blot analysis,qPT-PCR and confocal *** and the luciferase reporter assays were used to probe target genes interacting with ***:LPS caused a reduction in the viability and proliferation of HPMECs,as well as an elevation in the number of apoptotic ***,we observed that miR-30a-5p might play a role in preventing LPS-induced inhibition of cell damage and decreasing HPMEC apoptosis,suggesting the potential function of miR-30a-5p in this injury ***,we conﬁrmed that miR-30a-5p exerts its protective effect by regulating cell autophagy,possibly by targeting ***:Our study provided evidence that autophagy is a crucial aspect in the protective role of miR-30a-5p against LPS-induced HPMEC injury,identifying a promising target for sepsis-related endothelial cell injury.

关键词： Sepsis Endothelial cells MicroRNA Systemic inflammatory response syndrome

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HyperArc performance in radiotherapy and its correlations with number and volume of multiple brain metastases

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Radiation Medicine and Protection 2024年第2期5卷 139-144页

作者： Hongtao Chen Zihuang Li Guixiang Liao lijun wang Xiaonian Deng Heli Zhong Department of Radiation Oncology Shenzhen People's HospitalThe Second Clinical Medical CollegeJinan UniversityThe First Affiliated HospitalSouthern University of Science and TechnologyShenzhen518020China

Objective:To assess the performance and advantages of HyperArc for radiotherapy of multiple brain metastases with dosimetric parameters with respect to coplanar volumetric modulated arc radiotherapy(c-VMAT),and characterize implicit correlations between tumor features and dosimetric ***:This retrospective study involved 40 patients with multiple brain metastases(4–16 tumors,12.8–240.8 cm3)who received simultaneous radiotherapy at the Department of Radiation Oncology,Shenzhen People's Hospital from January 2019 to December *** HyperArc and c-VMAT plans were designed by the same and qualified physicist using the Eclipse system with Truebeam.A single isocenter and a 6 MV flattening filter-free(6FFF)photon beam were used for radiotherapy of multiple brain metastases in each *** parameters of tumors and organs at risk(OARs)were compared between HyperArc and c-VMAT ***-lations between tumor features(number and volume)and dosimetric parameters were revealed and ***,monitor units(MUs)of both plan types were recorded to assess rays utilization and delivery ***:Compared to c-VMAT plans,HyperArc plans achieved higher maximum dose(D_(max))(5.23%,t=7.87,P<0.01),but lower minimum dose(Dmin)(3.94%,t=-2.12,P=0.04)and mean dose(D_(mean))(1.05%,t=-3.29,P<0.01)for planning gross tumor volumes(PGTVs).The conformity index(CI),homogeneity index(HI),gradient index(GI)and R50%of PGTVs with HyperArc were better than those with c-VMAT,with the improve-ments of 20.78%,1.68%,19.83%and 36.20%,respectively(P<0.01).The dosimetric parameters of OARs were significantly improved in HyperArc plans compared to c-VMAT ***,the D_(max)and the D_(mean)to the brainstem decreased by 16.14%and 11.37%,*** D_(max)for eye_L decreased by 16.88%,for eye_R decreased by 11.67%,for optical nerve_L decreased by 12.56%,and for chiasm decreased by 18.12%.Few correlations were observed between the differences of CI/HI/GI

关键词： HyperArc Radiotherapy Multiple brain metastases Conformity

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Epidemiological characteristics of centenarian deaths in China during 2013-2020:A trend and subnational analysis

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Chinese Medical Journal 2024年第13期137卷 1544-1552页

作者： Fan Mao Weiwei Zhang Peng Yin lijun wang Jinling You Jiangmei Liu Yunning Liu Maigeng Zhou National Center for Chronic and Non-Communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijing 100050China

Background:Studies that comprehensively address the characteristics of centenarian deaths are *** present study aimed to depict the characteristics of centenarian deaths in China and their changing ***:Data on centenarian deaths between 2013 and 2020 were obtained from the national mortality surveillance system of China,including date,place of death(PoD),and underlying cause of death(CoD).Descriptive analyses were performed to understand the epidemiological characteristics,and a joinpoint regression model was adopted to examine the changing trends in the proportions of different PoDs,CoDs among centenarians,and centenarian deaths accounting for all deaths and deaths among people aged 65 years and ***:There were 46,938 registered centenarian deaths between 2013 and 2020 that included 34,311 females(73.10%)and 12,627 males(26.90%).January(12.05%),February(9.99%),and December(9.74%)were the top three months with the highest number of *** proportions of deaths that occurred in homes,hospitals,and nursing homes were 81.71%,13.63%,and 2.68%,*** proportion of deaths in nursing homes increased by 9.60%(95%confidence intervals[CIs],6.4-12.9%)from 2014 to *** disease(35.72%)was the leading cause of death,followed by respiratory diseases(17.63%),cerebrovascular disease(15.60%),and old age(11.22%).The proportion of respiratory diseases decreased by 4.8%(95%CI,-8.8 to-0.7%),and the proportion of deaths from old age decreased by 2.3%(95%CI,-4.4 to-0.1%)per *** had the highest proportions of deaths in hospitals(39.38%)and nursing homes(14.68%).Sichuan had the highest proportion of deaths attributed to respiratory diseases(32.30%),while Jiangsu(26.58%)and Zhejiang(23.61%)had the highest proportions of deaths from old ***:Unlike other countries,centenarian deaths in China are characterized by a higher proportion of home and heart disease deaths,and this death pattern differs across provinces.

关键词： Centenarians Death Aging Cardiovascular diseases Respiratory tract diseases Place of death Cause of death

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Mode-switchable dual-color infrared quantum cascade detector

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Photonics Research 2024年第2期12卷 253-259页

作者： YIXUAN ZHU SHENQIANG ZHAI KUN LI KAI GUO QIANGQIANG GUO JINCHUAN ZHANG SHUMAN LIU lijun wang FENGQI LIU JUNQI LIU Key Laboratory of Semiconductor Materials Science Beijing Key Laboratory of Low Dimensional Semiconductor Materials and DevicesInstitute of SemiconductorsChinese Academy of SciencesBeijing 100083China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

In this paper,a patch-antenna-array enhanced quantum cascade detector with freely switchable operating modes among mid-wave,long-wave,and dual-color was proposed and *** dual-color absorption occurs in a single active region through an optimized coupled miniband diagonal-transition subbands arrangement,and a successful separation of the operation regimes was realized by two nested antenna arrays with different patch sizes up to room *** 77 K,the 5.7-μm channel achieved a peak responsivity of 34.6 mA/W and exhibited a detectivity of 2.0×10^(10)Jones,while the 10.0-μm channel achieved a peak responsivity of 87.5 mA/W,giving a detectivity of 5.0×10^(10)*** a polarization modulation of the incident light,the minimum cross talk of the mid-wave and the long-wave operating modes was 1:22.5 and 1:7.6,*** demonstration opens a new prospect for multicolor infrared imaging chip integration technology.

关键词： antenna polarization quantum

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