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Proceedings of Anticancer Research 2024年第1期8卷 66-70页

作者： Chunyu Duan Gang Wang Bei Wang Man Xu lijuan gao Anesthesiology Department of Xi’an Chest Hospital Xi’an 710100China

Objective:This study aims to investigate the impact of combining general anesthesia with bronchial intubation and thoracic paravertebral nerve block during surgery for patients with tuberculous pyothorax.Methods:Eighty patients diagnosed with tuberculous pyothorax,admitted to the hospital between January 2023 and September 2023,were randomly selected for this study.The patients were divided into control and study groups using a numerical table method.The control group underwent general anesthesia with bronchial intubation,while the study group received general anesthesia with bronchial intubation in conjunction with thoracic paravertebral nerve block.Subsequently,the patients were monitored to assess mean arterial pressure,heart rate variations,and adverse reactions to anesthesia.Results:The study group exhibited significantly lower mean arterial pressure and heart rate levels during the post-surgical incision,immediate end of surgery,and immediate extubation periods compared to the control group(P<0.05).Furthermore,the Ricker and Ramsay scores in the study group were significantly lower than those in the control group(P<0.05).Conclusion:The combined use of general anesthesia via bronchial intubation and thoracic paravertebral nerve block has been found to stabilize mean arterial pressure and heart rate while providing effective sedation for surgical treatment in patients with tuberculous septic thorax.

关键词： General anesthesia and bronchial intubation Thoracic paravertebral nerve block Tuberculous pyothorax Surgical treatment effect

A Light and Simplified Branch Bending Method for Young Pear Trees

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Plant Diseases and Pests 2024年第2期15卷 19-21页

作者： Jintao XU Longfei LI Minghui JI Huan LIU lijuan gao Baofeng HAO Changli Institute of Pomology Hebei Academy of Agriculture and Forestry SciencesChangli 066600China

Aiming at high cost and low efficiency of conventional branch bending method in the modern intensive planting and labor-saving cultivation mode of young pear trees,this paper provides a new branch bending method with wide source of raw materials,cheap price and simple operation,which is also suitable for the management of low-age branches in the process of high grafting and upgrading of traditional big trees.

关键词： Pear tree Light and simplified Branch bending Method

Advances in Molecular Regulatory Mechanisms of Fruit Trees under Low Temperature Stress

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Plant Diseases and Pests 2024年第3期15卷 46-48页

作者： Huan LIU lijuan gao Minghui JI Longfei LI Jintao XU Baofeng HAO Changli Institute of Pomology Hebei Academy of Agriculture and Forestry SciencesChangli 066600China

The most recent research findings on the tolerance of fruit trees to cold stress are reviewed from a molecular perspective,including the perception and transduction of low temperature calcium signaling,CBF-dependent molecular regulatory mechanisms,non-CBF-dependent molecular regulatory mechanisms,and so forth.The objective is to provide a reference basis for further improving the cold resistance of fruit trees and cultivating new varieties of hardy plants.

关键词： Low temperature stress Fruit trees Growth and development Molecular mechanism Research progress

Evaluation of Cold Resistance and Semi-lethal Low Temperature(LT 50)of Nine Pear Cultivars

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Asian Agricultural Research 2024年第6期16卷 45-47页

作者： Huan LIU lijuan gao Jintao XU Minghui JI Longfei LI Baofeng HAO Changli Institute of Pomology Hebei Academy of Agriculture and Forestry SciencesChangli 066600China

[Objectives]To evaluate the cold resistance and semi-lethal temperature of pear cultivars,and provide a theoretical basis for the regional extension and breeding of cold-resistant pear cultivars.[Methods]Nine pear cultivars were used to study the changes in relative conductivity and cell injury rate of pear branches under low temperature stress,and the semi-lethal temperature(LT 50)of pear branches was analyzed by fitting Logistic equation.[Results]The relative conductivity and cell injury rate of pear branches took on the trend of slow increase,rapid increase,and slow increase the decrease of treatment temperature.The LC 50 of the nine pear cultivars were as follows:Nanguo pear-33.9℃,Wanyu-32.3℃,Red D Anjou-31.8℃,Jinfeng-31.3℃,Wujiuxiang-29.2℃,20 th Century Pear-29.1℃,Hanxiang-35.1℃,Yuluxiang-27.9℃and Korla Fragrant Pear-29.2℃.[Conclusions]The semi-lethal temperature could reflect the cold resistance of pear trees,and Wanxiang had better cold resistance.The evaluation of cold resistance and semi-lethal temperature of pear cultivars can provide theoretical basis for regional extension and breeding of cold-resistant pear cultivars.

关键词： Pear Cold resistance Semi-lethal temperature (LT 50 ) Low temperature

A method for Improving the Efficiency of Pear Tree Crossbreeding

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Agricultural Biotechnology 2024年第2期13卷 25-26,42页

作者： Jintao XU Longfei LI Minghui JI Huan LIU lijuan gao Yong GUO Yingjie WANG Baofeng HAO Changli Institute of Pomology Hebei Academy of Agriculture and Forestry SciencesChangli 066600China

In view of the short blooming period of pear tree crossbreeding and the complexity of pollination process, a method that can improve the efficiency of crossbreeding of pear trees was provided. Meanwhile, this method can also be applied to the study of pollen xenia effect, pollination tree selection and pure pollen collection in pear tree cultivation.

关键词： Pear tree Cross breeding Efficiency Method

TRDMT1 exhibited protective effects against LPS-induced inflammation in rats through TLR4-NF-κB/MAPK-TNF-αpathway

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Animal Models and Experimental Medicine 2022年第2期5卷 172-182页

作者： Zhengguang Li Xiaolong Qi Xu Zhang Lei Yu lijuan gao Weining Kong Wei Chen Wei Dong Lijun Luo Dan Lu Lianfeng Zhang Yuanwu Ma Key Laboratory of Human Disease Comparative Medicine National Health Commission of China(NHC)Institute of Laboratory Animal ScienceChinese Academy of Medical SciencesPeking Union Medicine CollegeBeijingChina National Human Diseases Animal Model Resource Center and Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases Institute of Laboratory Animal SciencePeking Union Medicine CollegeChinese Academy of Medical SciencesBeijingChina Neuroscience Center Chinese Academy of Medical SciencesBeijingChina

Background:Inflammation is a complex physiological and pathological process.Although many types of inflammation are well characterized,their physiological func-tions are largely unknown.tRNA aspartic acid methyltransferase 1(TRDMT1)has been implicated as a stress-related protein,but its intrinsic biological role is unclear.Methods:We constructed a Trdmt1 knockout rat and adopted the LPS-induced sepsis model.Survival curve,histopathological examination,expression of inflammatory fac-tors,and protein level of TLR4 pathway were analyzed.Results:Trdmt1 deletion had no obvious impact on development and growth.Trdmt1 de-letion slightly increased the mortality during aging.Our data showed that Trdmt1 strongly responded in LPS-treated rats,and Trdmt1 knockout rats were vulnerable to LPS treat-ment with declined survival rate.We also observed more aggravated tissue damage and more cumulative functional cell degeneration in LPS-treated knockout rats compared with control rats.Further studies showed upregulated TNF-αlevel in liver,spleen,lung,and serum tissues,which may be explained by enhanced p65 and p38 phosphorylation.Conclusions:Our data demonstrated that Trdmt1 plays a protective role in inflamma-tion by regulating the TLR4-NF-κB/MAPK-TNF-αpathway.This work provides useful information to understand the TRDMT1 function in inflammation.

关键词： inflammation knockout rat TLR4 pathway TNF-α Trdmt1

Recent developments of miniature ion trap mass spectrometers

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Chinese Chemical Letters 2018年第11期29卷 1578-1584页

作者： Qi Guo lijuan gao Yanbing Zhai Wei Xu School of Life Science Beijing Institute of Technology Beijing 100081 China Beijing Center Physical and Chemical Analysis Beijing 100089 China

With outstanding analytical performance and portability, miniature mass spectrometer is one of the most powerful tools for in-situ analysis. The miniaturization of mass spectrometers has lasted for more than ten years, during which a number of miniature mass spectrometers employing different techniques have been developed. Small-in-size, working at relatively high pressure region and capable of performing tandem mass spectrometry, ion trap is the most widely used mass analyzer in miniature mass spectrometer systems. The recent development of miniature ion trap mass spectrometer systems in the last ten years was reviewed in this paper. These instruments adopt different atmospheric pressure interfaces （APIs）, which are membrane inlets （MIs）, discontinuous atmospheric pressure interface （DAPI） and continuous atmospheric pressure interface （CAPI）. This review emphasizes on the mini mass spectrometry （MS） system that can be handheld by one person, but not the field-able ones that are too large to be hand-portable.

关键词： Miniature mass spectrometer lon trap Membrane inlet Discontinuous atmospheric pressure interface Continuous atmospheric pressure interface

Occurrence and Integrated Control of Psylla chinensis in Eastern Hebei Province

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Plant Diseases and Pests 2023年第1期14卷 14-16页

作者： lijuan gao Longfei LI Minghui JI Jintao XU Baofeng HAO Changli Institute of Pomology Hebei Academy of Agriculture and Forestry SciencesChangli 066600China

The paper introduces the damage characteristics and occurrence regularity of Psylla chinensis in pear orchards in eastern Hebei Province,and summarizes the integrated prevention and control techniques of P.chinensis,i... 详细信息

关键词： Eastern Hebei Province Psylla chinensis Occurrence Control

布地奈德联合肺表面活性物质预防呼吸窘迫综合征早产儿支气管肺发育不良的疗效观察

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中外医药研究 2024年第8期3卷 75-77页

作者：高丽娟郯城县第一人民医院山东临沂276100

目的:分析布地奈德联合肺表面活性物质(PS)预防呼吸窘迫综合征早产儿支气管肺发育不良(BPD)的效果。方法:选取2021年5月—2023年5月郯城县第一人民医院收治的呼吸窘迫综合征早产儿90例,依据随机数字表法分为对照组和研究组,各45例。对... 详细信息

目的:分析布地奈德联合肺表面活性物质(PS)预防呼吸窘迫综合征早产儿支气管肺发育不良(BPD)的效果。方法:选取2021年5月—2023年5月郯城县第一人民医院收治的呼吸窘迫综合征早产儿90例,依据随机数字表法分为对照组和研究组,各45例。对照组采用PS治疗,研究组采用布地奈德联合PS治疗。比较两组治疗效果。结果:治疗后,研究组动脉血二氧化碳分压(PaCO_(2))低于对照组,动脉血氧分压(PaO_(2))、pH值高于对照组,差异有统计学意义(P<0.05)。研究组BPD发生率显著低于对照组,差异有统计学意义(P<0.05)。研究组使用呼吸机时间、吸氧时间均短于对照组,差异有统计学意义(P<0.05)。研究组并发症发生率为8.88%,低于对照组的24.44%,差异有统计学意义(P<0.05)。结论:布地奈德联合PS治疗呼吸窘迫综合征早产儿的效果较好,能够对BPD进行有效预防,可改善患儿血气指标,降低并发症发生率,促进其早日康复。

关键词：早产儿呼吸窘迫综合征布地奈德肺表面活性物质

Occurrence and Control of Pear Rust in Eastern Hebei Province

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Plant Diseases and Pests 2022年第1期13卷 13-14页

作者： Longfei LI lijuan gao Jintao XU Minghui JI Baofeng HAO Changli Institute of Pomology Hebei Academy of Agricultural and Forestry SciencesChangli 066600China

In recent years, pear rust sometimes occurs in eastern Hebei area, resulting in early defoliation, fruit abscission and loss of fruit commodity value. In this paper, the incidence symptoms, regularity and causes of pear rust are summarized, and the comprehensive prevention and control measures of pear rust in eastern Hebei are put forward.

关键词： Pear Rust Incidence regularity Comprehensive prevention and control