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Fluctuating Potential Barrier System with Correlated Spatial Noises

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Communications in Theoretical Physics 2004年第6期41卷 899-902页

作者： lijing-Hui CenterforNonlinearStudies InstituteofAppliedPhysicsandComputationalMathematicsP.O.Box8009（28）Beijing100088China

In this paper, we study a fluctuating potential barrier system with correlated spatial noises. Study shows that for this system, there is the resonant activation over the fluctuating potential barrier, and that the co... 详细信息

关键词： spatial noise resonant activation

Imaging supermassive black hole shadows with a global very long baseline interferometry array

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Frontiers of physics 2022年第4期17卷 1-4页

作者： lijing Shao Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China National Astronomical Observatories Chinese Academy of SciencesBeijing 100012China

The imaging of two supermassive black holes by the Event Horizon Telescope Collaboration proved to a new level the correctness of Einstein's general relativity,regarding its prediction of black hole shadows in the hig... 详细信息

关键词： Event Horizon Telescope very long baseline interferometry,black hole black hole shadow

CRISPR-Cas系统在动物及植物中不同的递送方式研究进展

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解剖学杂志 2022年第2期45卷 153-156页

作者：范杏飞顾晶雯顾晓燕杜丽晶蒋俊锋王越海军军医大学组织学与胚胎学教研室上海200433

CRISPR-Cas系统的发现彻底改变了基因编辑技术领域,在多方面都有着广阔的前景。该系统主要有Cas蛋白和单链向导RNA组成,其功能的发挥高度依赖于各组分的有效递送。本篇综述对目前动植物中该系统组分的常用递送方式进行详细总结,并分析... 详细信息

CRISPR-Cas系统的发现彻底改变了基因编辑技术领域,在多方面都有着广阔的前景。该系统主要有Cas蛋白和单链向导RNA组成,其功能的发挥高度依赖于各组分的有效递送。本篇综述对目前动植物中该系统组分的常用递送方式进行详细总结,并分析其目前仍存在的问题。

关键词： CRISPR-Cas 基因编辑递送方式

Tests of gravitational symmetries with radio pulsars

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Science China(Physics,Mechanics & Astronomy) 2016年第9期59卷 10-32页

作者： lijing Shao Norbert Wex Max Planck Institute for Gravitational Physics (Albert Einstein Institute) Potsdam-Golm D-14476 Germany School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking University Beijing 100871 China Max-Planck-Institut fur Radioastronomie Bonn D-53121 Germany

Symmetries play important roles in modern theories of physical laws. In this paper, we review several experimental tests of important symmetries associated with the gravitational interaction, including the universality of free fall for self-gravitating bodies,time-shift symmetry in the gravitational constant, local position invariance and local Lorentz invariance of gravity, and spacetime translational symmetries. Recent experimental explorations for post-Newtonian gravity are discussed, of which, those from pulsar astronomy are highlighted. All of these tests, of very different aspects of gravity theories, at very different length scales, favor to very high precision the predictions of the strong equivalence principle(SEP) and, in particular, general relativity which embodies SEP completely. As the founding principles of gravity, these symmetries are motivated to be promoted to even stricter tests in future.

关键词： gravitation radio pulsars spacetime symmetry

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硫普罗宁对急性肝损害保护作用的实验研究

同济医科大学学报 1999年第4期28卷 338-339,349页

作者：唐望先虞涤霞杜荔菁但自力张文英李绍白同济医科大学附属同济医院肝病研究所武汉430030 武汉市第七医院肝病科武汉430071

为了研究硫普罗宁（Ｔｉｏｐｒｏｎｉｎ）对急性肝损害是否有保护作用，应用Ｄ－氨基半乳糖（Ｄ－ＧａｌＮ）造成大鼠急性肝损伤模型。实验分成正常组（Ｎ）、模型组（Ｄ－ＧａｌＮ）、模型＋硫普罗宁组（Ｄ－ＧａｌＮ＋Ｔ）、模型... 详细信息

为了研究硫普罗宁（Ｔｉｏｐｒｏｎｉｎ）对急性肝损害是否有保护作用，应用Ｄ－氨基半乳糖（Ｄ－ＧａｌＮ）造成大鼠急性肝损伤模型。实验分成正常组（Ｎ）、模型组（Ｄ－ＧａｌＮ）、模型＋硫普罗宁组（Ｄ－ＧａｌＮ＋Ｔ）、模型＋肝得健组（Ｄ－ＧａｌＮ＋Ｅ）。观察血清中丙氨酸转氨酶（ＡＬＴ）、肿瘤坏死因子（ＴＮＦ－α）、肝细胞及血浆中脂质过氧化物（ＬＰＯ）和肝组织及红细胞超氧化物歧化酶（ＳＯＤ）以及相关的病理变化。结果表明：模型＋硫普罗宁组（Ｄ－ＧａｌＮ＋Ｔ）及模型＋肝得健组（Ｄ－ＧａｌＮ＋Ｅ）血清中ＡＬＴ、ＴＮＦ－α及ＬＰＯ与模型组相比明显下降（Ｐ＜０．０１），而Ｄ－ＧａｌＮ＋Ｔ和Ｄ－ＧａｌＮ＋Ｅ两组的ＳＯＤ活性明显高于模型组（Ｄ－ＧａｌＮ）（Ｐ＜０．０１）。提示：硫普罗宁能降低血清中ＡＬＴ、ＴＮＦ－α的含量及肝组织中氧自由基的产生，降低血浆和组织中ＬＰＯ水平，并能提高细胞ＳＯＤ活性，从而减轻肝损伤。其对肝细胞的保护作用与肝得健一致。

关键词：硫普罗宁肝损害保护作用实验研究 D-GalN SOD

Flux Induced by Correlation Between Spatial Noises

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Communications in Theoretical Physics 2004年第5期41卷 715-718页

作者： lijing-Hui CenterforNonlinearStudies InstituteofAppliedPhysicsandComputationalMathematicsP.O.Box8009（28）Beijing100088China

In this paper, we study a spatially periodic system with spatial noises. Study shows that the correlation between the spatial noises can produce the nonzero flux, even in the absence of the asymmetry of the system.

关键词： flux spatial noise asymmetry

Efficient iterative adaptive pole placement algorithm

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Journal of Systems Engineering and Electronics 2004年第4期15卷 636-642页

作者： LiJunmin lijing YangLei DepartmentofAppliedMathematics XidianUniversityXi'an710071P.R.China

An iterative adaptive pole placement algorithm is presented. The stability and the convergence of the algorithmare respectively established. Since one-step iterative formulation in computing controller's parameters is used, the on-line computation cost is greatly reduced with respected to the traditional algorithm. The algorithm with the feed-forward can follow arbitrarily bounded output. The algorithm is also extended to multivariate case. Simulation examples show the efficiency and robustness of the algorithm.

关键词： Mathematical model Iterative algorithms Convergence Adaptive control Adaptation models Stability analysis Robustness

CHEMICAL WEATHERING PROCESSES AND ATMOSPHERIC CO_2 CONSUMPTION OF HUANGHE RIVER AND CHANGJIANG RIVER BASINS

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Chinese Geographical Science 2005年第1期15卷 16-21页

作者： lijing-ying ZHANGJing SchoolofMaterialsandEnvironmentalSciences QingdaoUniversityofScience＆TechnologyQingdao266042P.R.China ChemistryandChemicalEngineeringCollege OceanUniversityofChinaQingdao266003P.R.China／／StateKeyLaboratoryofEstuarineandCoastalResearchEastChinaNormalUniversityShanghai200062P.R.China

Rock weathering plays an important role in studying the long-term carbon cycles and global climatic change. According to the statistics analysis, the Huanghe (Yellow) River water chemistry was mainly controlled by evaporite and carbonate weathering, which were responsible for over 90% of total dissolved ions. As compared with the Huanghe River basin, dissolved load of the Changjiang (Yangtze) River was mainly originated from the carbonate dissolution. The chemical weathering rates were estimated to be 39.29t/(km(2).a) and 61.58t/(km(2).a) by deducting the HCO3- derived from atmosphere in the Huanghe River and Changjiang River watersheds, respectively. The CO2 consumption rates by rock weathering were calculated to be 120.84 x 10(3)mol/km(2) and 452.46 x 10(3)mol/km(2) annually in the two basins, respectively. The total CO2 consumption of the two basins amounted to 918.51 x 10(9)mol/a, accounting for 3.83% of the world gross. In contrast to other world watersheds, the stronger evaporite reaction and infirm silicate weathering can explain such feature that CO2 consumption rates were lower than a global average, suggesting that the sequential weathering may be go on in the two Chinese drainage basins.

关键词： Huanghe River basin Changjiang River basin chemical weathering rate CO2 consumption

Mechanistic insights into the adsorption and bioactivity of fibronectin on surfaces with varying chemistries by a combination of experimental strategies and molecular simulations

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Bioactive Materials 2021年第10期6卷 3125-3135页

作者： lijing Hao Tianjie Li Lin Wang Xuetao Shi Yan Fan Chang du Yingjun Wang School of Materials Science and Engineering South China University of TechnologyGuangzhou510640China Department of Physics The Chinese University of Hong KongShatinN.T.Hong Kong National Engineering Research Center for Tissue Restoration and Reconstruction Guangzhou510006China Key Laboratory of Biomedical Engineering of Guangdong Province Guangzhou510006China Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education Guangzhou510006China Innovation Center for Tissue Restoration and Reconstruction Guangzhou510006China Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) Guangzhou510005China

Fibronectin(Fn)is significant to the performance of biomaterials,and the chemistry of biomaterial surface play important roles in Fn adsorption and subsequent cell ***,the“molecular scale”mechanism is still ***,we combined experimental strategies with molecular simulations to solve this *** prepared self-assembled monolayers with varying chemistries,i.e.,SAMs-CH3,SAMs-NH2,SAMs-COOH and SAMs-OH,and characterized Fn adsorption and cell behaviors on ***,Monte Carlo method and all-atom molecular dynamics simulations were employed to reveal the orientation/conformation of Fn on *** found that SAMs-CH3 strongly adsorbed Fn via hydrophobic interactions,but show poor bioactivity as the low exposure of RGD/PHSRN motifs and the deformation of ***-NH2 and SAMs-COOH could adsorb Fn efficiently via vdW interactions,electrostatic interactions,hydrogen bonds and salt *** exhibited excellent bioactivity for cell adhesion,proliferation and osteogenic differentiation as high exposure of bioactive motifs on SAMs-NH2,or as the activation of other inferior cell-binding motifs on ***-OH showed poor Fn adsorption as the water ***,the adsorbed Fn displayed non-negligible bioactivity due to high exposure of PHSRN motif and large degree of protein *** believe that the revealed mechanism presents great potential to rationally design Fn-activating biomaterials.

关键词： Fibronectin Self-assembled hBMSCs Molecular dynamics simulation Orientation