检索结果-南通市图书馆

中国口腔颌面外科杂志 2005年第2期3卷 97-100页

作者： CHENWei-liang lijin-song YANGZhao-hui HUANGZhi-quan ZHANGBin DepartmentofOralandMaxillofacialSurgery TheSecondAffiliatedHospitalofSUNYat-senUniversity.Guangzhou510120GuangdongProvinceChina

PURPOSE: To evaluate the results of facial-cervico-pectoral rotation flap (FRF) and temporalis myofascial flap (TMF) in the repair of large soft tissue defect in oral and maxillofacial regions. METHODS: Six patients with malignant orbital tumors and/or maxillofacial tumors invading the orbital regions were treated with extensive resection. The major midfacial soft tissue defects were repaired by temporalis myofascial flap and facial-cervico-pectoral rotation flap. RESULTS: All flaps were successfully transferred; the result of facial aesthetics was satisfactory in all patients. Follow-up periods varied from 9 to 20 months (mean follow up period: 13.2 months) and all of the patients were alive during the follow-up period with one recurrence. CONCLUSIONS: The TMF and the FRF are easy to harvest, have low donor site morbidity, and are compatible with the principles of oncologic resection. It is the method of choice for repairing major orbito-maxillofacial skin defects following resection of the tumors.

关键词：上颌面损失手术切除肺肿瘤胸腔疾病

在线全文

学校读者我要写书评

暂无评论

家校合作下的德育改革

科教文汇 2014年第16期 14-14,27页

作者：宋丽瑾扬州大学教育科学学院江苏扬州225002

在教育改革进程中,如何实现德育的改革一直备受关注。近年来,走出单一的学校德育,走向家校合作的德育共育已成为众多学者的共识。本文从家校合作的角度出发,探讨家校德育共育中存在的问题,并提出相关的实施建议和策略。

关键词：家校合作德育共育德育改革

在线全文

学校读者我要写书评

暂无评论

接收机线性动态范围的分析与设计

科学技术与工程 2009年第6期9卷 1556-1559页

作者：宋里瑾中国空空导弹研究院洛阳471009

论述了接收机线性动态范围的理论,并对接收机非线性失真产生的原因及其对整个系统所产生的影响进行分析。介绍1dB压缩点、三阶截点和三阶互调三个最常用的接收机线性度衡量指标。结合工程实际,给出了接收机线性动态范围的设计方法和扩... 详细信息

论述了接收机线性动态范围的理论,并对接收机非线性失真产生的原因及其对整个系统所产生的影响进行分析。介绍1dB压缩点、三阶截点和三阶互调三个最常用的接收机线性度衡量指标。结合工程实际,给出了接收机线性动态范围的设计方法和扩大系统动态范围的方法。

关键词：动态范围线性自动增益控制

Patients with breath test positive are necessary to be identified from irritable bowel syndrome:a clinical trial based on microbiomics and rifaximin sensitivity

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2022年第14期135卷 1716-1727页

作者： Zuojing Liu Shiwei Zhu Meibo He Mo Li Hui Wei Lu Zhang Qinghua Sun Qiong Jia Nan Hu Yuan Fang lijin song Chen Zhou Heqing Tao John Y Kao Huaiqiu Zhu Chung Owyang Liping Duan Department of Gastroenterology Peking University Third HospitalHaidian DistrictBeijing 100191China Department of Ultrasound Peking University Third HospitalHaidian DistrictBeijing 100191China Institute of Systems Biomedicine School of Basic Medical SciencesPeking University Health Science CenterBeijing 100191China Department of Biomedical Engineering College of EngineeringPeking UniversityBeijing 100187China Division of Gastroenterology Department of Internal MedicineUniversity of Michigan Health System6520 MSRB ISPC 56821150 West Medical Center DriveAnn ArborMI 48109USA

Background:As a non-invasive and effective diagnostic method for small intestinal bacterial overgrowth(SIBO),wild-use of breath test(BT)has demonstrated a high comorbidity rate in patients with diarrhea-predominant irritable bowel syndrome(IBS-D)and *** overlapping with SIBO respond better to rifaximin therapy than those with IBS-D *** microbiota plays a critical role in both of these two *** aimed to determine the microbial difference between IBS-D overlapping with/without SIBO,and to study the underlying mechanism of its sensitivity to ***:Patients with IBS-D were categorized as BT-negative(IBSN)and BT-positive(IBSP).Healthy volunteers(BT-negative)were enrolled as healthy *** patients were clinically evaluated before and after rifaximin treatment(0.4 g bid,4 weeks).Blood,intestine,and stool samples were collected for cytokine assessment and gut microbial ***:Clinical complaints and microbial abundance were significantly higher in IBSP than in *** contrast,severe systemic inflammation and more active bacterial invasion function that were associated with enrichment of opportunistic pathogens were seen in *** symptoms of IBSP patients were relieved in different degrees after therapy,but the symptoms of IBSN rarely *** also found that the presence of IBSN-enriched genera(Enterobacter and Enterococcus)are unaffected by rifaximin ***:IBS-D patients overlapping with SIBO showed noticeably different fecal microbial composition and function compared with IBS-D *** better response to rifaximin in those comorbid patients might associate with their different gut microbiota,which suggests that BT is necessary before IBS-D diagnosis and use of ***:Chinese Clinical Trial Registry,ChiCTR1800017911.

关键词： Irritable bowel syndrome Small intestinal bacterial overgrowth Breath test Gut microbiota Rifaximin

在线全文

学校读者我要写书评

暂无评论

基于ADS的多通道下变频器仿真设计

遥测遥控 2011年第2期32卷 29-32页

作者：宋里瑾海森宋小勇中航工业空空导弹研究院洛阳471009

重点讨论L波段多通道下变频器的设计与仿真。采用自上向下的方法,以Agilent ADS软件为平台建立仿真模型,选用S参数和谐波平衡仿真工具对多通道下变频器信道进行设计仿真,经过优化得到低噪声、高动态的仿真指标,实现多通道变频方案的可... 详细信息

重点讨论L波段多通道下变频器的设计与仿真。采用自上向下的方法,以Agilent ADS软件为平台建立仿真模型,选用S参数和谐波平衡仿真工具对多通道下变频器信道进行设计仿真,经过优化得到低噪声、高动态的仿真指标,实现多通道变频方案的可行性论证。

关键词：多通道下变频 S参数谐波平衡

集成萌芽期生长和苗期生理指标高通鉴选番茄耐盐品种

在线全文

学校读者我要写书评

暂无评论

植物生理学报 2022年第4期58卷 733-745页

作者：宋立金丁日升曹荷莉郭悦霍礼琪王嫣然武凝楠中国农业大学中国农业水问题研究中心北京100083 甘肃武威绿洲农业高效用水国家野外科学观测研究站甘肃武威733009

确定最优耐盐指标并鉴选耐盐番茄品种对提高盐碱地作物用水效率至关重要,但集成萌芽期生长和苗期生理指标高通鉴选耐盐品种的研究还较少。本文选用10个不同番茄品种,分别在萌芽期和苗期设置了4个盐分水平(0、50、100、150 mmol·L^(-1)... 详细信息

确定最优耐盐指标并鉴选耐盐番茄品种对提高盐碱地作物用水效率至关重要,但集成萌芽期生长和苗期生理指标高通鉴选耐盐品种的研究还较少。本文选用10个不同番茄品种,分别在萌芽期和苗期设置了4个盐分水平(0、50、100、150 mmol·L^(-1)盐水灌溉,S1~S4)。测定了萌芽期芽长、根长、鲜重和干重,计算了发芽势、发芽率和发芽指数;苗期气孔导度、叶水势、叶绿素、株高、茎粗、地上鲜重和干重。结果表明,耐盐品种在受到盐分胁迫后,发芽指数和芽长、气孔导度和叶水势变化幅度较小。因此,它们可以分别作为萌芽期和苗期耐盐指标。通过对集成萌芽期生长和苗期生理指标鉴选得出‘京丹8号’是10个番茄品种中最耐盐的品种。总之,本文提出的集成萌芽期和苗期耐盐性评价方法,具有周期短、准确性高的特点,可用于耐盐品种的高通鉴选。

关键词：番茄萌芽期苗期耐盐指标品种鉴选集成方法

在线全文

学校读者我要写书评

暂无评论

具核梭杆菌灌胃对大鼠肠道菌群的影响

山东大学学报（医学版） 2018年第7期56卷 7-14页

作者：宋立锦顾湘李理想李铭左秀丽李延青山东大学齐鲁医院消化内科山东济南250012

目的探究具核梭杆菌(Fusobacterium nucleatum)灌胃对健康大鼠肠道菌群的影响。方法将16只SD雄性大鼠随机分为2组(每组8只),处理组在大鼠第4、5、6、7、8周龄分别用具核梭杆菌灌胃1次,对照组在相同时间点以等量生理盐水灌胃。在大鼠第3... 详细信息

目的探究具核梭杆菌(Fusobacterium nucleatum)灌胃对健康大鼠肠道菌群的影响。方法将16只SD雄性大鼠随机分为2组(每组8只),处理组在大鼠第4、5、6、7、8周龄分别用具核梭杆菌灌胃1次,对照组在相同时间点以等量生理盐水灌胃。在大鼠第3、8、12周末收集粪便,提取DNA后通过Illumina Miseq平台进行16S rRNA基因高通量测序。应用蛋白印迹法检测大鼠粪便中针对具核梭杆菌的特异性IgA。结果第3周时,两组在菌群多样性、主要菌门水平方面的差异无统计学意义。第8周时,处理组菌群多样性明显低于对照组(P=0.009);处理组的厚壁菌门、变形菌门含量低于对照组,拟杆菌门含量高于对照组,差异均有统计学意义(P<0.05)。第12周时,处理组菌群多样性明显高于对照组(P=0.021),两组大鼠肠道菌群的主要菌门水平差异无统计学意义。同时,具核梭杆菌灌胃刺激机体产生了特异性IgA。结论具核梭杆菌通过未定植方式,对肠道菌群产生了影响,并可持续一定时间。具核梭杆菌刺激产生的特异性IgA可能是其不能在肠道定植的原因之一。

关键词：具核梭杆菌肠道菌群高通量测序大鼠

A Symplectic Based Neural Network Algorithm for Quantum Controls under Uncertainty

在线全文

学校读者我要写书评

暂无评论

Communications in Computational Physics 2022年第5期31卷 1525-1545页

作者： Jingshi Li song Chen lijin Wang Yanzhao Cao Department of Mathematics and Statistics Nanjing University of Information Science and TechnologyNanjingJiangsu210044P.R.China Department of Mathematics&Statistics University of Wisconsin–La CrosseLa CrosseWI54601USA School of Mathematical Sciences University of Chinese Academy of SciencesBeijing100049P.R.China Department of Mathematics&Statistics Auburn UniversityAuburnAL36830USA

Robust quantum control with uncertainty plays a crucial role in practical quantum *** paper presents a method for solving a quantum control problem by combining neural network and symplecticfinite difference *** neural network approach provides a framework that is easy to establish and *** the same time,the symplectic methods possess the norm-preserving property for the quantum system to produce a realistic solution in *** construct a general high dimensional quantum optimal control problem to evaluate the proposed method and an approach that combines a neural network with forward Euler’s *** analysis and numerical experiments confirm that the neural network-based symplectic method achieves significantly better accuracy and robustness against noises.

关键词： Quantum(noise)control neural network symplectic methods norm-preservation

Frequency and Distribution of Microsatellites in the Genome of Filamentous Fungus,Neurospora crassa

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2005年第2期4卷 118-124页

作者： LICheng-yun lijin-bin ZHOUXiao-gang ZHANGShao-song XUMing-hui PlantProtectionCollege YunnanAgriculturalUniversityKunming650201PR.China PlantProtectionResearchInstitute YunnanAcademyofAgriculturalSciencesKunming650205PR.China BiotechnologyResearchInstitute YunnanAcademyofAgriculturalSciencesKunming650223P.R.China

A total of 38.0 Mb of publicly available DNA sequence in Neurospora crassa was researched for mono- to hexanucleotide simple sequence repeats (SSR or microsatellite) to determine the type, size and frequency. A total of 14 788 SSRs were observed in the whole genomic DNA sequence, about one every 2.57 kb, with the criteria of SSR length >15 bp and 80% matches. The most abundant microsatellite was trinucleotide repeat, the number was 4 729, followed by hexanucleotide and mononucleotide repeats, the numbers were 2 940 and 2 489 respectively, and the least abundance was dinucleotide repeat, only 691 were found. Among the 10 082 ORFs, 4 094 SSRs were harbored in 2 373 ORF (no intron) of the organism. One thousand and fifty six ORFs harbored only one SSR. Similar with other organisms, tri- and hexanucleotide repeats were predominant in ORFs, 54.1 and 48.8% of tri- and hexanucleotide repeats were distributed in ORF region. The density of these two motifs was overpresented in coding regions, because ORF region and coding region constitutes only 46 and 38.3% of genomic sequence, respectively. Upstream and downstream 300 bp of regulatory regions were high density regions of SSRs, particularly density of pentanucleotide SSR in upstream region was as high as five times of average density in genomic DNA, density of di- and tetranucleotide SSR was also more than two times of average density. The density of penta-, tetra-, di- and mononucleotide SSRs was relatively higher than average density. There were 47 SSRs in mitochondria 64 840 bp DNA sequence, their distribution is similar with genomic DNA sequence. These results suggested that SSRs were clustered in regulatory regions of genomic DNA.

关键词： Neurospora crassa Genome Microsatellite or SSR (Simple sequence repeat) Frequency Distribution Genetic marker

不同分子质量大豆蛋白和鸡肉酶解物的美拉德反应产物风味特征分析

在线全文

学校读者我要写书评

暂无评论

食品科学技术学报 2023年第3期41卷 148-162页

作者：汤龙宋焕禄王丽金北京工商大学食品与健康学院北京100048

为了研究不同分子质量的肽在美拉德反应后的风味特征,以大豆蛋白和鸡肉为原料酶解得到蛋白酶解物。对酶解物超滤分离得到小于1 000 Da、1 000~5 000 Da和大于5 000 Da的不同分子质量肽组分,并对大豆蛋白和鸡肉酶解物完全酸水解得到复合... 详细信息

为了研究不同分子质量的肽在美拉德反应后的风味特征,以大豆蛋白和鸡肉为原料酶解得到蛋白酶解物。对酶解物超滤分离得到小于1 000 Da、1 000~5 000 Da和大于5 000 Da的不同分子质量肽组分,并对大豆蛋白和鸡肉酶解物完全酸水解得到复合氨基酸。在得到的肽段和氨基酸中添加一定量的木糖,构建美拉德反应模型。对美拉德反应产物感官特性进行评价,再采用气相色谱-质谱联用、高效液相色谱对挥发性和不挥发性化合物进行分析。结果表明:在2种不同蛋白来源的酶解物的美拉德反应产物中,共鉴定出挥发性化合物69种,其中吡嗪和呋喃硫醇等肉香味化合物的含量最高。统计分析表明:不同分子质量的肽和游离氨基酸的挥发性化合物存在明显差异。小于1 000 Da的肽在美拉德反应过程促进了吡嗪类化合物的生成,其中包括了吡嗪、5-甲基-2-乙基吡嗪、2,5-二甲基-3-乙基吡嗪、三甲基吡嗪、2-乙酰基吡咯等挥发性化合物。与肽相比,游离氨基酸有利于含硫化合物如呋喃硫醇类和噻吩类物质的生成。有29种挥发性化合物的相对气味活性值大于1。偏最小二乘回归研究了气味化合物与感官评价之间的相关性,发现小于1 000 Da的肽与基本的肉味和浓厚味密切相关,而大于5 000 Da的肽与苦味和焦煳味密切相关。在美拉德反应后,分子质量大于5 000 Da的肽数量显著减少;分子质量1 000~5 000 Da的肽降解可以补充消耗的游离氨基酸;分子质量小于1 000 Da的肽容易发生交联和聚合现象而含量增加,其产物对风味的影响明显增强,能更好地体现基本的肉味、鲜味和浓厚味。希望研究可以为利用蛋白质酶解物生产美拉德反应产物的应用提供理论支撑和指导。

关键词：蛋白水解物肽段游离氨基酸美拉德反应大豆蛋白鸡肉