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急性白血病患者焦虑抑郁与生活质量间的关系:家庭韧性的中介作用与教育程度的调节作用

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空军军医大学学报 2024年第9期45卷 1018-1022,1027页

作者：穆赫孜王黎红任国平柳琴陈唱唱崔怡张翠燕张银玲空军军医大学护理系陕西西安710032 空军军医大学唐都医院血液内科陕西西安710038

目的考察急性白血病(AL)患者焦虑抑郁对生活质量的影响和作用机制,探讨家庭韧性的中介作用以及教育程度的调节作用。方法采用白血病特异性生活质量量表、医院焦虑抑郁量表、中文版家庭韧性量表对286名AL患者进行测量。结果生活质量与家... 详细信息

目的考察急性白血病(AL)患者焦虑抑郁对生活质量的影响和作用机制,探讨家庭韧性的中介作用以及教育程度的调节作用。方法采用白血病特异性生活质量量表、医院焦虑抑郁量表、中文版家庭韧性量表对286名AL患者进行测量。结果生活质量与家庭韧性(r=0.482,P1)呈显著正相关,与焦虑抑郁(r=-0.706,P1)呈显著负相关。家庭韧性在AL患者焦虑抑郁和生活质量的关系中起部分中介作用,教育程度在焦虑抑郁对生活质量的影响路径中发挥调节作用。结论研究有助于了解AL患者焦虑抑郁对生活质量的影响机制,对干预和改善患者的生活质量具有一定的现实意义。

关键词：急性白血病焦虑抑郁家庭韧性教育程度生活质量

Melatonin enhances radiofrequency-induced NK antitumor immunity,causing cancer metabolism reprogramming and inhibition of multiple pulmonary tumor development

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Signal Transduction and Targeted Therapy 2021年第10期6卷 3019-3032页

作者： Ming Li Bingjie Hao Menghuan Zhang Russel J.Reiter Shumeng Lin Tiansheng Zheng Xiangyun Chen Yanbei ren Liduo Yue Baigenzhin Abay Guojie Chen Xiao Xu Yufeng Shi lihong Fan Department of Respiratory Medicine Shanghai Tenth People's HospitalTongji University School of MedicineShanghaiChina Institute of Energy Metabolism and Health Shanghai Tenth People's HospitalTongji University School of MedicineShanghaiChina Tongji University Cancer Center Shanghai Tenth People's Hospital of Tongji UniversitySchool of MedicineTongji UniversityShanghaiChina Clinical Center For Brain And Spinal Cord Research Tongji UniversityShanghaiChina Department of Cell Systems and Anatomy University of Texas Health San AntonioSan AntonioTexasUSA National Scientific Medical Research Center AstanaKazakhstan State Key Laboratory of Molecular Biology Shanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceChinese Academy of SciencesShanghaiChina

Surgery is the comm on treatme nt for early lung cancer with multiple pulm onary no dules,but it is often accompanied by the problem of significant malignancy of other nodules in non-therapeutic *** this study,we found that a combined treatment of local rad iofreq ue ncy ablati on(RFA)and melatonin(MLT)greatly improved clinical outcomes for early lung cancer patie nts with multiple pulmonary nodules by minimizing lung function injury and reducing the probability of malignant transformation or enlargement of nodules in non-ablated ***,as demonstrated in an associated mouse lung tumor model,RFA not only effectively remove treated tumors but also stimulate antitumor immunity,which could inhibit tumor growth in non-ablated *** enhanced RFA-stimulated NK activity and exerted synergistic antitumor effects with *** and proteomics analyses of residual tumor tissues revealed enhanced oxidative phosphorylation and reduced acidification as well as hypoxia in the tumor microenvironment,which suggests reprogrammed tumor metabolism after combined treatment with RFA and *** of residual tumor further revealed the depressed activity of MAPK,NF-kappa B,Wnt,and Hedgehog pathways and upregulated P53 pathway in tumors,which was in line with the inhibited tumor *** RFA and MLT treatment also reversed the Warburg effect and decreased tumor *** findings thus demonstrated that combined treatment of RFA and MLT effectively inhibited the malignancy of non-ablated nodules and provided an innovative non-invasive strategy for treating early lung tumors with multiple pulmonary *** registration:***,identifier ChiCTR2100042695,http://***/***?proj=120931.

关键词： metabolism immunity inhibited

Particle-associated polycyclic aromatic hydrocarbons in a desert region

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Particle-associated polycyclic aromatic hydrocarbons in a de...

Fault-sand combination modes and hydrocarbon accumulation in Binhai fault nose of Qikou Sag, Bohai Bay Basin, East China

第七届海峡两岸气胶技术研讨会暨第二届空气污染技术研讨会

作者： Yang Xiaoyang1、Zhang Wenjie1、Wang Xinhua1、ren lihong1、Chen Jianhua1 1.Chinese Research Academy of Environmental Sciences (CRAES)

＜正＞Airborne particulate matter （PM） samples for PM10 and PM2.5 were collected at five sites （one urban site,two rural sites and two industrial sites） in the Ordos District of Inner Mongolia,a desert area of Nor... 详细信息

关键词： PAH、Asian Dust、airborne particulate matter

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Petroleum Exploration and Development 2019年第5期46卷 919-934页

作者： ZHOU lihong HAN Guomeng DONG Yueqi SHI Qianru MA Jianying HU Jinnan ren Shichao ZHOU Kejia WANG Jincheng SI Weiliu Dagang Oilfield Company PetroChinaTianjin 300280China

Based on seismic and logging data,taking the downthrow fault nose of Binhai fault in Qikou Sag as the object of study,we analyzed fault characteristics,sand body distribution,fault-sand combinations and hydrocarbon accumulation to reveal the hydrocarbon enrichment law in the fault-rich area of fault depression lake *** results show that the Binhai Cenozoic fault nose is characterized by east-west zoning,the main part of the western fault segment is simple in structure,whereas the broom-shaped faults in the eastern segment are complex in structure,including several groups of *** difference of fault evolution controls the spatial distribution of sand *** sand bodies are in continuous large pieces in the downthrow fault trough belt along the Gangdong Fault in the middle segment of the fault nose,forming consequent fault-sand combination;whereas the fault activity period of the eastern part of the fault nose was later,and the sand bodies controlled by paleogeomorphology are distributed in multi-phase north-south finger-shaped pattern,forming vertical fault-sand combination pattern matching with the *** configuration between faults and sand bodies,and oil sources and caprocks determine the vertical conductivity,plane distribution and vertical distribution of oil and *** oil and gas accumulation modes,*** main fault hydrocarbon supply-fault sand consequent matching-oil accumulation in multi-layers stereoscopically and fault system transportation-fault sand vertical matching-oil accumulation in banded overlapping layers occur in the middle and eastern segments of the fault nose respectively,and they control the difference of oil and gas distribution and enrichment degree in the Binhai fault nose.

关键词： Bohai Bay Basin Qikou Sag Binhai fault nose sandstone development mechanism fault-sand combination oil and gas accumulation reservoir control mechanism

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Influence of ren and Du meridian electro-acupuncture on neural stem cell proliferation and extracellular signal-regulated kinase pathway in a rat model of focal cerebral ischemia injury

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Neural Regeneration Research 2010年第6期5卷 433-438页

作者： Wenshu Luo Haibo Yu Zhuoxin Yang Min Pi lihong Diao Xiaodan Rao Department of Acupuncture and Moxibustion Shenzhen Municipal Hospital of Traditional Chinese Medicine Shenzhen 518033 Guangdong Province China Department of Rehabilitation Shekou People's Hospital Shenzhen 518000 Guangdong Province China

BACKGROUND： Studies have shown that electro-acupuncture at the ren meridian could improve proliferation of subventricular zone neural stem cells in cerebral-ischemic rats. However, there are few reports on the influence of electro-acupuncture at the Du meridian on neural stem cell proliferation. OBJECTIVE： To observe the influence of electro-acupuncture at ren and Du meridians on neural stem cell proliferation in the subventricular zone and altered signal transduction in cerebral ischemia rats. DESIGN, TIME AND SETTING： A randomized, controlled, animal experiment was performed at the Laboratory of Human Anatomy, Medical College of Sun Yat-sen University from May 2006 to February 2008. MATERIALS： Mouse anti-rat bromodeoxyuridine （BrdU） monoclonal antibody was provided by Sigma, USA; mouse anti-rat nestin monoclonal antibody and extracellular signal-regulated protein kinase （ERK） specific inhibitor PD98059 were provided by Calbiochem, Germany; acupuncture needle was provided by Suzhou Acupuncture Supplies, China. METHODS： A total of 126 rats were randomly assigned to four groups： model （n = 36）, Du meridian （n = 36）, ren/Du meridian （n = 36）, and ren/Du meridian ＋ PD98059 （n = 18）. Rats in the ren/Du meridian ＋ PD98059 group were observed on days 7 （n = 6） and 14 （n = 12） after cerebral ischemia injury. Rats in the model, Du meridian, and ren/Du meridian groups were observed on days 7, 14, and 28 after cerebral ischemia injury, with 12 rats per group at each time point. Thread occlusion was used to establish middle cerebral artery occlusion models. Electro-acupuncture was performed at renzhong （DU 26） and Baihui （DU 20） acupoints in the Du meridian group, as well as Chengjiang （RN 24）, Guanyuan （RN 4）, renzhong, and Baihuiacupoints in the ren/Du meridian and ren/Du meridian ＋ PD98059 groups 2 days after model establishment. In addition, electro-acupuncture stimulation with disperse-dense waves was performed, with 30 Hz disperse wave, 100 Hz dense wave, and 5 V intensi

关键词： cerebral ischemia electro-acupuncture extracellular signal-regulated protein kinase middle cerebral artery occlusion brain injury neural regeneration cerebral infarction

基于3DMax的城市道路路灯三维自动建模方法

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测绘与空间地理信息 2024年第5期47卷 93-95,99页

作者：赵全哲王飒任达梁笑语曲洋宏王美玲石丽红纪博文侯宁辽宁宏图创展测绘勘察有限公司辽宁沈阳110000

针对传统手工三维建模存在的效率低、成本高、精度低等不足,在进行上海道路实景三维项目时,提出一种基于3DMax的城市道路路灯三维自动建模方法。首先在3DMax中建立不同类型的路灯模型,之后通过脚本程序筛选道路采集提供的二维矢量数据... 详细信息

针对传统手工三维建模存在的效率低、成本高、精度低等不足,在进行上海道路实景三维项目时,提出一种基于3DMax的城市道路路灯三维自动建模方法。首先在3DMax中建立不同类型的路灯模型,之后通过脚本程序筛选道路采集提供的二维矢量数据以确定路灯的尺寸和方向等属性信息,最后实现路灯在相应位置上的批量自动建模。经过项目试验,将自动建模方法与手工建模方法进行比较,结果表明,自动建模方法提高了建模效率、节约了成本,且可保证道路附属设施数据的完整性。

关键词： 3DMax 道路附属设施路灯三维自动建模

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中国首例拉沙热病例报道

新发传染病电子杂志 2024年第4期9卷 1-5页

作者：冉启惠陈红黄亮孟令彬陈竹任利红杜清张钉山李晨曦郑永利成都市公共卫生临床医疗中心重症医学科四川成都610066 成都市公共卫生临床医疗中心科研教学部四川成都610066 成都市公共卫生临床医疗中心放射科四川成都610066 成都市公共卫生临床医疗中心药物临床试验机构四川成都610066

拉沙热(Lassa fever)是一种由拉沙病毒(Lassa virus,LASV)引起的发热性传染病。该疾病于1969年在尼日利亚首次被报告,后在西非地区流行。LASV主要通过大鼠的尿液或粪便传播给人类,也可能通过接触感染者的血液、粪便或其他身体分泌物在... 详细信息

拉沙热(Lassa fever)是一种由拉沙病毒(Lassa virus,LASV)引起的发热性传染病。该疾病于1969年在尼日利亚首次被报告,后在西非地区流行。LASV主要通过大鼠的尿液或粪便传播给人类,也可能通过接触感染者的血液、粪便或其他身体分泌物在人与人之间传播。拉沙热常见症状包括发热、头痛、呕吐、腹痛和咳嗽。本文报道了中国首例确诊拉沙热病例,该病例发病前曾在西非几内亚工作,发病后LASV血清荧光定量PCR检测和IgG抗体检测均为阳性,确诊拉沙热。确诊后,患者接受了利巴韦林联合对症支持治疗,病情逐渐好转。本研究全面回顾了该病例的流行病学史、临床症状、诊断过程、治疗措施及转归,以提高医务人员对拉沙热的认识和防治水平。通过对本病例的深入分析,为未来类似病例的快速识别与有效应对提供科学依据,促进公共卫生体系对输入性传染病防控能力的提升。

关键词：拉沙热临床症状流行病学诊断治疗预防

吻合血管腓骨瓣治疗股骨头缺血性坏死的疗效观察

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骨科临床与研究杂志 2024年第2期9卷 72-77页

作者：魏建伟蒋颖良李开虎刘立宏张理军陶世斌熊珏铭任珍锐董忠根中南大学湘雅二医院骨科长沙410011

目的分析吻合血管腓骨瓣治疗股骨头缺血性坏死(ONFH)的临床疗效。方法2016年3月至2022年9月中南大学湘雅二医院骨科收治股骨头缺血性坏死患者23例(26髋),按照国际骨循环协会(ARCO)分期:Ⅱ期6例、ⅢA期15例、ⅢB期5例。术前髋关节Harris... 详细信息

目的分析吻合血管腓骨瓣治疗股骨头缺血性坏死(ONFH)的临床疗效。方法2016年3月至2022年9月中南大学湘雅二医院骨科收治股骨头缺血性坏死患者23例(26髋),按照国际骨循环协会(ARCO)分期:Ⅱ期6例、ⅢA期15例、ⅢB期5例。术前髋关节Harris评分为(60.9±9.0)分。所有患者均采用吻合血管的腓骨瓣进行治疗,腓骨瓣近端距离腓骨头约10 cm,腓骨瓣长度约7 cm。除少数早期病例外,其余病例术中均未使用植骨材料或内固定装置。术后定期随访,进行影像学检查评估腓骨瓣愈合及股骨头坏死区域变化情况,评价髋关节功能。结果术后无伤口感染、下肢深静脉血栓形成等并发症。患者均获得随访,随访时间13~93个月。末次随访患髋Harris评分为(90.9±4.5)分,与术前相比差异有统计学意义(P=0.000)。影像学未见腓骨瓣移位,均愈合良好,无坏死区域进展。结论吻合血管的腓骨瓣治疗股骨头缺血性坏死能够有效改善患者髋关节功能。改良的手术方法和技术,使得腓骨瓣的切取、植入、固定等更加精准、有效。

关键词：股骨头坏死动静脉吻合吻合血管的游离腓骨移植

综合性护理在蠕形螨睑缘炎病人中的应用效果观察

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护理研究 2021年第6期35卷 1114-1116页

作者：任丽红山西省眼科医院山西030002

目的:探讨综合性护理应用于蠕形螨睑缘炎病人的效果。方法:选取2019年2月—2020年2月我院收治的70例蠕形螨睑缘炎病人作为研究对象,按照首诊顺序将病人随机分为对照组和观察组,每组35例。对对照组病人进行睑板腺按摩的常规护理及用药指... 详细信息

目的:探讨综合性护理应用于蠕形螨睑缘炎病人的效果。方法:选取2019年2月—2020年2月我院收治的70例蠕形螨睑缘炎病人作为研究对象,按照首诊顺序将病人随机分为对照组和观察组,每组35例。对对照组病人进行睑板腺按摩的常规护理及用药指导,对观察组病人进行综合性护理,比较两组病人护理2个月后的治疗效果、护理满意度及治疗依从性。结果:护理后观察组病人治疗总有效率为97.14%,满意率为94.29%,治疗依从性得分为(96.65±2.21)分,均高于对照组[治疗总有效率为88.57%,满意率为77.14%,治疗依从性得分为(78.28±3.94)分],两组比较差异均有统计学意义(P<0.05)。结论:将综合性护理应用于蠕形螨睑缘炎病人有利于提高病人治疗效果、满意度及治疗依从性。

关键词：综合性护理蠕形螨睑缘炎疗效满意度依从性护理