检索结果-南通市图书馆

Study of Nanoskin ECM-Bacterial Cellulose Wound Healing/United Arab Emirates

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biomaterials and Nanobiotechnology 2016年第2期7卷 109-117页

作者： Saqer Al Mualla Raed Farahat Pierre Basmaji Gabriel Molina de Olyveira ligia maria manzine costa José Domingos da costa Oliveira Gino Bruno Francozo Al Qassimi Hospital/Kuwait Hospital Sharjah United Arab Emirates Innovatec’s-Biotechnology Research and Development S&atilde o Carlos Brazil Department of Physical Chemistry Universidade Estadual Paulista (UNESP) Araraquara Brazil Materials Engineering Department S&atilde o Carlos School of Engineering University of S&atilde o Paulo S&atilde o Carlos Brazil

Natural extracellular matrices (ECMs) perform the tasks necessary for tissue formation, maintenance, regulation and function, providing a powerful means of controlling the biological performance of regenerative materials. In addition, biomedical materials have claimed attention because of the increased interest in tissue engineering materials for wound care and regenerative medicine. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization, cell support and Natural Extracellular Matrix (ECM) Scaffolds. In this work, we present the extracellular matrix (ECM) using the bacterial cellulose (Nanoskin®) which regulates cell behavior by influencing cell proliferation, survival, shape, migration and differentiation. Bacterial cellulose fermentation process is modified before the bacteria are inoculated for mimicking ECM to cells support and built new local material for wound healing. Chemical groups influences and thermal behavior in bacterial cellulose were analyzed using transmission infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA), respectively. Besides, In vivo analysis was evaluated with clinical study at Sharjah Kuwait Hospital.

关键词： Bacterial Cellulose (Nanoskin) Natural Nanocomposites Regenerative Medicine Stem Cells

Novel LDPE/EVA Nanocomposites with Silver/Titanium Dioxide Particles for Biomedical Applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

材料科学与工程（中英文B版） 2011年第4期1卷 516-522页

作者： Gabriel Molina de Olyveira ligia maria manzine costa Ant6nio Joss Felix de Carvalho Pierre Basmaji Luiz Antonio Pessan Department of Materials Engineering-Polymers Federal University of S6o Carlos-UFSCar 13565-905 S6o Carlos SP Brazil Department of Materials Engineering S6o Paulo University 13566-590 S6o Carlos SP Brazil Innovatec ＇s-Biotechnology Research and Development Sao Carlos SP Brazil

Natural ECM-Bacterial Cellulose Wound Healing—Dubai Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biomaterials and Nanobiotechnology 2015年第4期6卷 237-246页

作者： Safwat Mohd. El-Hoseny Pierre Basmaji Gabriel Molina de Olyveira ligia maria manzine costa Abdulwahid M. Alwahedi José Domingos da costa Oliveira Gino Bruno Francozo Al Qassimi Hospital Sharjah United Arab Emirates Innovatec’s-Biotechnology Research and Development S&atildeo Carlos Brazil Department of Physical Chemistry UNESP Araraquara Brazil Department of Chemistry USP FFCLRP Ribeir&atildeo Preto Brazil

Bacterial cellulose (BC) can be used in wide area of applied scientific, especially for tissue regeneration and regenerative medicine, lately, bacterial cellulose mats are used in the treatment of skin conditions such as burns and ulcers, because of the morphology of fibrous biopolymers serving as a support for cell proliferation, its pores allow gas exchange between the organism and the environment. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization, cell support and Natural Extracellular Matrix (ECM) Scaffolds. In this scope, Natural ECM is the ideal biological scaffold since it contains all the components of the tissue. The development of mimicking biomaterials and hybrid biomaterial can further advance directed cellular differentiation without specific induction. The extracellular matrix (ECM) contains several signals that are received by cell surface receptors and contribute to cell adhesion and cell fate which control cellular activities such as proliferation, migration and differentiation. As such, regenerative medicine studies often rely on mimicking the natural ECM to promote the formation of new tissue by host cells, and characterization of natural ECM components is vital for the development of new biomimetic approaches. In this work, the bacterial cellulose fermentation process is modified by the addition of vegetal stem cell to the culture medium and natural materials before the bacteria are inoculated. In vivo behavior using natural ECM for regenerative medicine is presented.

关键词： Bacterial Cellulose (Nanoskin) Natural Nanocomposites Regenerative Medicine Stem Cells

Special Nanoskin-ACT-Biological Membranes from Deep Wounds

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biomaterials and Nanobiotechnology 2018年第1期9卷 79-88页

作者： Saqer Al Mualla Mashael Al Nabooda Noura Salim Salman Pierre Basmaji Gabriel Molina De Olyveira ligia maria manzine costa Jose Domingos Da costa Oliveira Gino Bruno Francozo Al Qassimi Hospital/Kuwait Hospital SharjahUnited Arab Emirates Biotechnology Research and Development Sao CarlosBrazil Department of Nanomedicine and Nanotoxicology IFSC-USPSao CarlosBrazil Materials Engineering Department Sao Carlos School of EngineeringUniversity of Sao PauloSao PauloBrazil

Bacterial cellulose (BC) is established as a newest biomaterial, and it can be used for medical and odontology applications. In addition, it has called attention for uses such as membrane for wound care and tissue engineering. In this work, the bacterial cellulose fermentation process is modified by the addition of natural materials before the bacteria are inoculated. In vivo behavior using natural ECM for regenerative medicine is presented and completed wound healing process is 3 months.

关键词： Bacterial Cellulose(Nanoskin^(█))&ACT(Advanced Cell Therapy) Natural Nanocomposites Tissue Engineering

Fecal calprotectin and endoscopic scores: The cornerstones in clinical practice for evaluating mucosal healing in inflammatory bowel disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第24期30卷 3022-3035页

作者： Marcia Henriques de Magalhães costa ligia Yukie Sassaki Júlio maria Fonseca Chebli Department of Clinical Medicine Fluminense Federal UniversityRio de Janeiro 24210-200Brazil Department of Internal Medicine Medical SchoolSão Paulo State University(Unesp)Botucatu 18618-686São PauloBrazil Division of Gastroenterology Department of MedicineUniversity Hospital of The Federal University of Juiz de ForaUniversity of Juiz de Fora School of MedicineJuiz de Fora 36036-247Minas GeraisBrazil

Managing inflammatory bowel disease(IBD)is becoming increasingly complex and personalized,considering the advent of new advanced therapies with distinct mechanisms of *** mucosal healing(MH)is a pivotal therapeutic goal in IBD management and can prevent IBD progression and reduce flares,hospitalization,surgery,intestinal damage,and colorectal *** proactive disease and therapy assessment is essential to achieve better control of intestinal inflammation,even if subclinical,to alter the natural course of *** monitoring of fecal calprotectin(FC)levels and interval endoscopic evaluations are cornerstones for evaluating response/remission to advanced therapies targeting IBD,assessing MH,and detecting subclinical ***,we comment on the article by Ishida et al Moreover,this editorial aimed to review the role of FC and endoscopic scores in predicting MH in patients with ***,we intend to present some evidence on the role of these markers in future targets,such as histological and transmural *** prospective multicenter studies with a stricter MH criterion,standardized endoscopic and histopathological analyses,and virtual chromoscopy,potentially including artificial intelligence and other biomarkers,are desired.

关键词： Fecal calprotectin Endoscopic scores Mucosal healing Histological healing Ulcerative colitis Inflammatory bowel diseases

Effect of Solution Concentration on the Electrospray/Electrospinning Transition and on the Crystalline Phase of PVDF

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Materials Sciences and Applications 2010年第4期1卷 247-252页

作者： Lígia maria manzine costa Rosário Elida Suman Bretas Rinaldo Gregorio 不详

A study was conducted regarding the effect of concentration of poly (vinylidene fluoride) (PVDF)/N,N-dimethylformamide (DMF) and PVDF/DMF/acetone solutions on the transition between electrospray and electrospinning and on the formation of the ? and ? crystalline phases of PVDF. The crystalline phases present in the samples, crystallinity and morphology were determined by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and scanning electron microscopy (SEM), respectively. Low concentration solutions resulted in films consisting of small droplets (electrospray) containing predominantly the ? phase. High concentration solutions resulted in a non-woven mesh of nano-to-micron diameter fibers (electrospinning) containing exclusively the ? phase. These results showed that, the formation of this phase in the electrospinning is related mainly to the solvent evaporation rate, and not to drawing experienced by the polymer during the process. Solvent type affected the amount of crystalline phase present, the boundary concentration between the two processes and the average diameter of fibers. Meshes processed by electrospinning display a degree of crystallinity higher than the films obtained by electrospray.

关键词： Poly(Vinylidene Fluoride) (PVDF) Electrospinning Electrospray Crystalline Phase Fibers Morphology