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Clinical features, treatment strategies and outcomes of craniocervical junction arteriovenous fistulas: a cohort study of 193 patients

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Stroke & Vascular Neurology 2024年第1期9卷 18-29页

作者： Yongjie Ma Zihao Song Yinqing Wang Jiachen Wang Chuan He Guilin Li peng Zhang Tao Hong Liyong sun peng Hu Ming Ye Hongqi Zhang Department of Neurosurgery Xuanwu Hospital Capital Medical University

Background Craniocervical junction(CCJ)arteriovenous fistulas(AVFs)are *** current treatment strategies for AVFs with different angioarchitecture need to be *** present study aimed to analyse the correlation between angioarchitecture and clinical characteristics,share our experience in treating this disease and identify risk factors associated with subarachnoid haemorrhage(SAH)and poor *** A total of 198 consecutive patients with CCJ AVFs from our neurosurgical centre were retrospectively *** patients were grouped according to their clinical manifestations,and their baseline clinical characteristics,angioarchitecture,treatment strategies and outcomes were *** The patients’median age was 56 years(IQR 47–62 years).The majority of patients were men with 166(83.8%)*** most common clinical manifestation was SAH(52.0%),followed by venous hypertensive myelopathy(VHM)(45.5%).The most common CCJ AVFs type was dural AVF,with 132(63.5%)*** most frequent fistula location was C-1(68.7%)and dural branch of vertebral artery(70.2%)was the most involved arterial feeders for *** most common direction of venous drainage was descending intradural drainage(40.9%),followed by ascending intradural drainage(36.5%).Microsurgery was the most common treatment strategy applied for 151(76.3%)patients,15(7.6%)patients were treated with interventional embolisation only,and 27(13.6%)received both interventional embolisation and microsurgical *** learning curve for microsurgery only was analysed by cumulative summation method,and the turning point was the 70th case,and blood loss in post-group was lower than that in pre-group(p=0.034).At the last follow-up,there were 155(78.3%)patients with favourable outcomes(modified Rankin Scale(mRS)<3).Age≥56(OR 2.038,95%CI 1.039 to 3.998,p=0.038),VHM as the clinical manifestation(OR 4.102,95%CI 2.108 to 7.982,p<0.001)and pretreatment mRS≥3(OR 3.127,95%CI 1.617 to 6.047,p<0

关键词： patients treatment hypertensive

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Advancing flood susceptibility modeling using stacking ensemble machine learning: A multi-model approach

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Journal of Geographical Sciences 2024年第8期34卷 1513-1536页

作者： YANG Huilin YAO Rui DONG Linyao sun peng ZHANG Qiang WEI Yongqiang sun Shao AGHAKOUCHAK Amir School of Geography and Tourism Anhui Normal UniversityWuhu 241002AnhuiChina Changjiang River Scientific Research Institute Wuhan 430015China Advanced Interdisciplinary Institute of Environment and Ecology Beijing Normal UniversityZhuhai 519087GuangdongChina Hunan Institute of Water Resources and Hydropower Research Changsha 410007China State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China Department of Civil and Environmental Engineering University of California IrvineIrvineCA 92697USA

Flood susceptibility modeling is crucial for rapid flood forecasting, disaster reduction strategies, evacuation planning, and decision-making. Machine learning(ML) models have proven to be effective tools for assessing flood susceptibility. However, most previous studies have focused on individual models or comparative performance, underscoring the unique strengths and weaknesses of each model. In this study, we propose a stacking ensemble learning algorithm that harnesses the strengths of a diverse range of machine learning models. The findings reveal the following:(1) The stacking ensemble learning, using RF-XGBCB-LR model, significantly enhances flood susceptibility simulation.(2) In addition to rainfall,key flood drivers in the study area include NDVI, and impervious surfaces. Over 40% of the study area, primarily in the northeast and southeast, exhibits high flood susceptibility, with higher risks for populations compared to cropland.(3) In the northeast of the study area,heavy precipitation, low terrain, and NDVI values are key indicators contributing to high flood susceptibility, while long-duration precipitation, mountainous topography, and upper reach vegetation are the main drivers in the southeast. This study underscores the effectiveness of ML, particularly ensemble learning, in flood modeling. It identifies vulnerable areas and contributes to improved flood risk management.

关键词： flood susceptibility assessment machine learning stacking ensemble learning flood drivers XiangjiangRiverBasin

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Low-concentration and multi-component NMHCs capture from oil field exhaust using porous ZIF-8/iso-hexadecane slurry

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Green Chemical Engineering 2024年第2期5卷 245-256页

作者： Kun Li Han Tang Jin Cai Chun Deng Bei Liu Yunlei peng Changyu sun Guangjin Chen State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing102249China

Non-methane hydrocarbons(NMHCs)are a common type of volatile organic compounds(VOCs)pollutant in the petrochemical industry and have attracted widespread attention because of their adverse health effects and environmental *** this paper,we report a new porous slurry formed with zeolitic imidazolate framework-8(ZIF-8)and iso-hexadecane to capture the low-concentration and multi-component NMHCs(mainly ethane(C_(2)H_(6)),propane(C_(3)H_(8)),and n-butane(n-C_(4)H_(10)))from the oil field *** sorption capacity of C_(2)H_(6)in the slurry is significantly higher than that of nitrogen(N_(2))and methane(CH_(4)).Moreover,the slurry demonstrated a clear advantage for C_(2)H_(6)over N_(2)and CH_(4)in competitive adsorption through the pressure-drop *** the NMHCs capture experiments,the C_(3)H_(8)and n-C_(4)H_(10)concentrations after purification can be reduced to below 100 ppm,while the C_(2)H_(6)concentration can reach approximately 180 *** encouragingly,in the breakthrough tests,the slurry exhibits a perfect kinetic separation selectivity for multi-component ***,to avoid structural collapse of ZIF-8 material during long-term use in acidic and wet environments,a certain amount of 2-methylimidazole was retained in the slurry as a protective agent in the material synthesis *** this way,the ZIF-8 materials in the slurry can retain the stable characteristic structure in an aqueous and acidic environment and keep the capture capacity for NMHCs without *** believe the porous ZIF-8/iso-hexadecane slurry is a promising capture agent for low-concentration and multi-component NMHCs with strong purification capacity and stability.

关键词： VOCs capture NMHCs capture MOFs ZIF-8 Porous slurry

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South China Sea Typhoon Hagibis enhanced Xinfengjiang Reservoir seismicity

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Earthquake Science 2024年第3期37卷 210-223页

作者： peng Zhang Xinlei sun Yandi Zeng Zhuo Xiao Runqing Huang State Key Laboratory of Isotope Geochemistry Guangzhou Institute of GeochemistryGuangzhou 510640China University of Chinese Academy of Sciences Beijing 100049China College of Geosciences Chengdu University of TechnologyChengdu 610059China College of Artificial Intelligence Guangxi Minzu UniversityNanning 530006China

There was an evident increase in the number of earthquakes in the Xinfengjiang Reservoir from June to July 2014 after the landing of Typhoon *** understand the spatial and temporal evolution of this microseismicity,we built a high-precision earthquake catalog for 2014 and relocated 2275 events using recently developed methods for event picking and catalog *** occurred in the southeastern part of the reservoir,with the preferred fault plane orientation aligned along the Heyuan *** total seismic energy peaked when the typhoon passed through the reservoir,and seismicity correlated with typhoon *** contrast,a limited seismic response was observed during the later Typhoon *** data regarding the water level in the Xinfengjiang Reservoir and seismicity frequency changes in the Taiwan region during these two typhoon events,we suggest that typhoon activity may increase microseism energy by impacting fault stability around the Xinfengjiang *** a fault can be activated also depends on how close the stress accumulation is to its failure point.

关键词： typhoon seismicity analysis earthquake detection spatio-temporal evolution characteristics microseisms

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Theoretical investigations of population trapping phenomena in atomic four-color,three-step photoionization scheme

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Chinese Physics B 2024年第3期33卷 333-340页

作者：卢肖勇孙亚鹏 Science and Technology on Particle Transport and Separation Laboratory Tianjin 300180China Department of Engineering Physics Tsinghua UniversityBeijing 100084China

The four-color three-step selective photoionization process of atom is very important in laser isotope separation *** population trapping phenomena and their influences are studied theoretically in monochromatic and non-monochromatic laser fields based on the density matrix theory in this *** evolutions of the photoionization properties of the four-color,three-step process are *** population trapping effects occur intensely in monochromatic excitation,while it gradually turns weak as the laser bandwidth *** effects of bandwidth,Rabi frequency,time delay,and frequency detuning on the population trapping effect are investigated in monochromatic and non-monochromatic laser *** effects of laser process parameters and atomic parameters on the effective selective photoionization are also *** ionization probability and selectivity factors,as evaluation indexes,are difficult to improve synchronously by adjusting systematic ***,the existence of metastable state may play a negative role when its population is low enough.

关键词： population trapping metastable state selective photoionization laser bandwidth

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Morphology effect on catalytic performance of ebullated-bed residue hydrotreating over Ni-Mo/Al_(2)O_(3)catalyst:a kinetic modeling study

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Green Chemical Engineering 2024年第1期5卷 60-67页

作者： Zhe Liu Juncong Yuan Zongzhuang sun Xiang Feng Yibin Liu Huihong Zhu Chong peng Chaohe Yang State Key Laboratory of Heavy Oil Processing China University of PetroleumQingdao266580China Dalian Research Institute of Petroleum and Petrochemicals SINOPECDalian116045China State Key Laboratory of Fine Chemicals Dalian University of TechnologyDalian116024China

Upgrading of vacuum residue is of prime industrial significance due to the increasing demand for light *** the effect of catalyst morphology on vacuum residue hydrotreating performance by kinetic modeling is therefore of great ***,kinetic analysis of hydrodemetallization(HDM)and hydrodeconradsoncarbon-residue(HDCCR)performances on industrial Ni-Mo/Al_(2)O_(3)catalysts with spherical and cylindrical morphologies in ebullated-bed were evaluated for more than 1600 *** was found that the percentage of light impurities easier to be removed on spherical catalysts were 78.20%and 39.43%in HDM and HDCCR reactions,respectively,higher than 65.20%and 17.50%on cylindrical *** suggests that catalyst morphology affects the impurity removal ability and the impurity properties,resulting in better hydrotreating performance of spherical *** work not only combines catalyst morphology with impurity removal capability through kinetic modeling,but also provides new insights into the design of efficient hydrotreating catalysts.

关键词： Morphology effect Kinetic analysis Vacuum residue Hydrotreating

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Graphene-anchored sodium single atoms:A highly active and stable catalyst for transesterification reaction

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Nano Research 2024年第6期17卷 4979-4985页

作者： Song-Song peng Yao Nian Xing-Ru Song Xiang-Bin Shao Chen Gu Zhi-Wei Xing Shi-Chao Qi peng Tan You Han Xiao-Qin Liu Lin-Bing sun State Key Laboratory of Materials-Oriented Chemical Engineering Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM)College of Chemical EngineeringNanjing Tech University30 South Puzhu RoadNanjing 211816China School of Chemical Engineering and Technology Tianjin UniversityTianjin 300072China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192China

Solid strong base catalysts have received considerable attention in various organic reactions due to their facile separation,neglectable corrosion,and environmental *** great progress has been made in the preparation of solid strong base catalysts,it is still challenging to avoid basic sites aggregation on support and active sites loss in reaction ***,we report a tandem redox strategy to prepare Na single atoms on graphene,producing a new kind of solid strong base catalyst(Na1/G).The base precursor NaNO_(3)was first reduced to Na2O by graphene(400℃)and successively to single atoms Na anchored on the graphene vacancies(800℃).Owing to the atomically dispersed of basicity,the resultant catalyst presents high activity toward the transesterification of methanol and ethylene carbonate to synthesize dimethyl carbonate(turnover frequency(TOF)value:125.7 h^(−1)),which is much better than the conventional counterpart Na2O/G and various reported solid strong bases(TOF:1.0-90.1 h^(−1)).Furthermore,thanks to the basicity anchored on graphene,the Na1/G catalyst shows excellent durability during *** work may provide a new direction for the development of solid strong base catalysts.

关键词： solid strong base catalyst basic sites redox graphene single Na atoms

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Effect of cytochrome P4502C19(CYP2C19)gene polymorphism and clopidogrel reactivity on long term prognosis of patients with coronary heart disease after PCI

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Journal of Geriatric Cardiology 2024年第1期21卷 90-103页

作者： Cheng-Yan HU Yan-Ling WANG Zhen-Xing FAN Xi-peng sun Shuai WANG Zhi LIU Department of Geriatrics Fu Xing HospitalCapital Medical UniversityBeijingChina Department of Cardiology Xuanwu Hospital Capital Medical UniversityBeijingChina Emergency Department of Xuanwu Hospital Capital Medical UniversityBeijingChina

Objective To investigate the impact of CYP2C19 gene polymorphism on clopidogrel reactivity and its association with longterm clinical outcome in patients with coronary heart disease(CHD)undergoing percutaneous coronary intervention(PCI).Methods In total,675 patients were *** on the platelet inhibition rate,patients were categorized into two groups:clopidogrel low responsiveness(CLR)and normal clopidogrel responsiveness(NCR).The CLR group was divided into ticagrelor and clopidogrel group based on the antiplatelet drugs used in the follow-up *** were classified into three groups(normal metabolizer,intermediate metabolizer,and poor metabolizer)based on the CYP2C19 *** aimed to evaluate the impact of CYP2C19 gene polymorphism on clopidogrel *** cumulative rates of 12-month all-cause deaths,major adverse cardiovascular events(MACCEs),and bleeding events were *** CLR was observed in 44.4%of the overall *** differences were observed in the platelet inhibition rate of clopidogrel among the three metabolic genotypes(P0.05).Conclusions Low response to clopidogrel in CHD patients is correlated with CYP2C19 gene ***2C19 genotyping combined with platelet reactivity is an independent predictor of 12-months MACCEs in patients with clopidogrel treatment after PCI,which is better than either test alone.

关键词： CYP2C19 drugs PCI

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Thermal comfort in a building with Trombe wall integrated with phase change materials in hot summer and cold winter region without air conditioning

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Energy and Built Environment 2024年第1期5卷 58-69页

作者： Jie Li Yuan Zhang Ziyang Zhu Jiangtian Zhu Jing Luo Fen peng Xiaoqin sun School of Energy and Power Engineering Changsha University of Science and TechnologyChangshaHunan 410114PR China

Trombe wall and phase change materials(PCMs)are two effective ways to regulate indoor thermal ***,Trombe wall surfers from overheating in summer and PCMs suffer from low heat transfer rate caused by the limited thermal *** compensate the shortcomings of the two methods,this paper proposed a Trombe wall system integrated with *** on a light-weight building envelope in Changsha,China,the thermal comfort of 10 kinds of Trombe wall systems with PCMs with a melting temperature of 18-28℃ were *** the integrated indoor discomfort duration(I_(D)),integrated indoor discomfort degree-hour(I_(DH)),indoor air temperature(T_(in)),PCM liquid fraction(γ)and heat flux across wall(q)as evaluation indexes,the indoor thermal comfort was assessed in hot summer and cold winter *** show that the Trombe wall helped PCMs complete the phase change process *** wall with PCM25 next to the wall inner surface possessed the lowest annual I_(D) and I_(DH),as 2877 h and 12,974℃·h,*** with the values in a traditional building,the I_(D) and I_(DH) were reduced by 7.01% and 14.14%.In order to give full play to the heat storage and heat release of the Trombe wall with PCMs,PCMs with phase change temperature 7℃ lower than the peak ambient temperature in summer or 8℃ higher than the winter night temperature was recommended according to regional climate conditions.

关键词： Trombe wall Phase change materials Integrated indoor discomfort duration Integrated discomfort degree-hour Liquid fraction

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Mitochondria at the Crossroads of Cholestatic Liver Injury:Targeting Novel Therapeutic Avenues

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Journal of Clinical and Translational Hepatology 2024年第9期12卷 792-801页

作者： Xutao Li Tianyin Ruan Siyuan Wang Xin sun Chenghai Liu Yuan peng Yanyan Tao Institute of Liver Diseases Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChina Shanghai Key Laboratory of Traditional Chinese Clinical Medicine ShanghaiChina Key Laboratory of Liver and Kidney Diseases Ministry of EducationShanghaiChina

Bile acids are byproducts of cholesterol metabolism in the liver and constitute the primary components of *** of bile flow leads to cholestasis,characterized by the accumulation of hydrophobic bile acids in the liver and *** accumulation can exacerbate liver *** review discussed recent developments in understanding how bile acids contribute to liver damage,including disturbances in mitochondrial function,endoplasmic reticulum stress,inflammation,and autophagy *** play a pivotal role in cholestatic liver injury by influencing hepatocyte apoptosis and *** findings linking bile acids to liver damage highlight new potential treatment targets for cholestatic liver injury.

关键词： Bile acids Mitochondria Endoplasmic reticulum Inflammatory Cholestatic liver injury Review

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